HunterMeeting2015 Program

Crowne Plaza Hunter ValleyLovedale NSW Australia

Australias Premier Systems, Cell and Developmental Biology Meetings

Convenor:Rohan TeasdaleCo-convenor:Patrick Humbert

Hunter Systems Meeting | 15th Hunter Meeting | 8th National Imaging Workshop | March 16-20, 2015 | 3

Table of ContentsGeneral Information .......................................................... 2-3

Society Sponsors ...................................................... 4-5, 8

Echibitors .......................................................... 6-7

Posters ........................................................ 9-14

Hunter Systems Program ...................................................... 15-18

Hunter Cell Program ...................................................... 18-29

Imaging Workshop ................................................ 22-24, 26

Social events

Dinner - the West Terrace and Gallery ............................... 16

Dinner on The 1st Tee ........................................................ 20

Dinner in The Lovedale Room ........................................... 24

Conference Dinner the Pergola .......................................... 27

Author index ...................................................... 30-33

Contact address list ...................................................... 34-40

Exhibition and Poster Layout ...............................................back page

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The Hunter Meeting convenors and committee are pleased to welcome all international guests, speakers, delegates and sponsors to the 2015 Hunter Meeting Week and thank you for your presentations, attendance and support.

CBMI Executive | wwwPresident: Professor David James Vice-President: Professor Peter GunningTreasurer: A/Professor Rohan Teasdale Secretary/Public Officer: Professor Sally Dunwoodie

Hunter Meeting Committee | wwwA/Professor Rohan Teasdale, Convenor Professor Patrick Humbert, co-ConvenorProfessor Wanjin Hong, International MemberProfessor Natasha Harvey Professor Edna HardemanProfessor Patrick Humbert Professor Sharad Kumar Professor Christina Mitchell Professor Linda RichardsProfessor Sarah Russell A/Professor Paul Thomas

Conference organisation and Desktop publishing | Magic Touch Consultancies | www.mtci.com.au

GENERAL INFORMATION

8TH NATIONAL IMAGING WORKSHOPIn 2015, the Workshop is included in the conference registration fee. It is held over two afternoons, Wednesday and Thursday.

Wednesday sessions consist of talks and presentations from 1:15-5:30pm, with breaks taken with the Exhibition and Posters. Company sponsors presenting in the Workshop are: Coherent Scientific and Life Technologies. The Imaging Plenary Lecture sponsored by LasTek, La Lavision rounds out the Imaging Workshop sessions for Wednesday.

The Thursday afternoon segment is Demonstrations and Exhibition, held in the Exhibition Suite. Lasers can be used in the demonstration booths and delegates will see the scope configuration. The demo will use fixed material. Demo movies, perhaps from users, will provide the details of live cell uses. A light Tea will be served both afternoons.

ACCOMMODATIONAccommodation in the conference hotel includes breakfast, which is taken in Red Salt Restaurant from 7am. All incidentals are at the delegates expense and should be paid directly to the hotel at check-out.

ATM/BANKING An ATM is located near Reception and at the Pokolbin Village and Hunter Valley Gardens. Full banking services in Cessnock.

AV | DATA PROJECTIONThose speaking first, perhaps eMail in advance, or bring immediately upon your arrival to Semillon 3. You may also use your own computer, which can be controlled from the lectern. Please bring your talk/laptop to Semillon 3 at your earliest convenience, and at least two sessions in advance of your presentation slot. Any special connections for your laptop, bring early to the AV desk.

CHECK-IN/OUTIf your room is not ready when you arrive, leave your luggage with Concierge. Those driving up might like to fit in some wine-tasting in the morning (Pokolbin wineries are the closest. Saddlers Creek...).

For those sharing accommodation, please check out together to facilitate the process for the Reception Staff. Those on the Sydney Airport bus, may store luggage with Concierge at Reception.

CONFERENCE HOTEL | PARKINGCrowne Plaza Hunter Valley,430 Wine Country Drive,Lovedale, NSW, 2325, Australia | T: +61 2 4991 000Parking is free and located near your hotel room/villa. You will receive a map on check-in with those details. Concierge has suggestions for pre/post conference activities.

DRESS CODEA jacket or jumper/sweater for evening dinners (outdoors) and sitting in air-conditioned conference rooms is advisable. Neat and casual dress; comfortable footwear. Bring swimmers, sunscreen, hat. Something sparkly for the Conference Dinner? Brolly - there may be showers and you will be walking to breakfast etc.

ELECTRICITYAustralia uses 240V mains power, and 3-point power sockets. I have a few limited-country adaptors, TO BORROW if you are desperate.

EXHIBITION AND LAYOUTThe Exhibition starts earlier in the meeting and finishes on Thursday after Tea. It is located with the Poster display in the Exhibition Suite and is open from morning until the close of the evening Poster sessions. Be sure to visit the Exhibitors in the breaks and particularly at Poster and Exhibition times.

EXHIBITORS AND WEBSITE LINKSBIO-RAD | CARL ZEISS | COHERENT SCIENTIFICEPPENDORF | GE HEALTHCARE | IN VITRO TECHNOLOGIES | LASTEK - LA VISION BIOTECLEICA MICROSYSTEMS | LIFE TECHNOLOGIESMERCK MILLIPORE | MILTENYI BIOTECNEWSPEC | SIGMA-ALDRICHTHERMO FISHER SCIENTIFIC

Exhibitors covered table is 1.8m long and 0.75m wide; there is power to your table. Backboards if ordered are placed behind your numbered table. Plans are at the entrance doors to the area during set-up, and on the back page. Pack-up is immediately after Tea on Thursday.

The 2015 Hunter Meeting Week | March 16-20, 2015 | Crowne Plaza Hunter Valley, Lovedale NSW Australia Hunter Systems Meeting | 15th Hunter Meeting | 8th National Imaging Workshop | March 16-20, 2015 | 54

INTERNETWireless Internet connection is available at Crowne Plaza. Code is available from Reception.

NAME BADGESPlease wear yours at all times. We are not the only guests in the hotel and it is important for Staff to be able to recognise those in our group.

NETWORKINGCrowne Plaza has grounds and public spaces around the venue where you can meet and talk - or use your room or villa.

NO-SMOKINGHotel rooms, restaurants and public spaces are smoke-free in Australia.

POSTERS AND WINEThere are 3 Poster sessions: Posters hung for the whole meeting; Posters hung in the Systems Meeting; and posters hung in the Cell Meeting.

Check the final program for when to set yours up and which session you are in. Posters are numbered in THIS Program and correspondingly numbered boards are located with the Exhibition in the Exhibition Suite. Posters should be portrait in orientation; and are A0, A1 or in the suggested dimensions of 1.2 m high by 1m wide. Velcro dots are provided on the numbered boards.

Posters should be hung at the commencement of your meeting. Posters are viewed in the designated evening and afternoon sessions and in the breaks. Wine is served with the evening Poster Sessions from the designated Exhibitor tables. Posters to be removed by the end of your meeting, or end of Tea on Thursday - no responsibility taken for Posters not removed by then.

REGISTRATION DESKLocated in the Exhibition Suite. Collect name badge from here.

PROGRAMThe program is provided as a PDF file. Programs are not printed. Notepads are provided by the hotel, however if you wish to make extensive annotations, please print off your own copy and bring with you.

REFRESHMENTS | CONFERENCE DINNERA platter lunch is served before the meetings commence. Coffee, lunch, afternoon teas and dinner as per the conference program. All teas and lunches are served with the Exhibition and posters in the Exhibition Suite.

Wine with dinner: Monday, Tuesday and Thursday nights: a bottle of red and white wine on each table, and then cash bar. Beverages may be put on your room account.

Wednesday evening in the Lovedale Bar and Restaurant: one complimentary beverage, then cash bar.

The conference dinner is held on Thursday evening under the Pergola.

SYDNEY AIRPORT COACHESRemember: if you arrive at T1 or T2, you must make your way to T3, Qantas Domestic Terminal to meet the bus driver INSIDE near the Hertz Rental Car counter. Schedule | Notes

RETURNWednesday 18th March departing Crowne Plaza Hunter Valley @ 9:30am, after breakfast. Collect your packed morning tea from the Pre-Function Foyer.

Friday 20th March departing Crowne Plaza Hunter Valley @ 1:00pm, immediately after sessions conclude. Collect your packed lunch from Reception. VENUECrowne Plaza Hunter Valley is a stylish hotel, set amongst the rolling greens of the golf course. Guests may organise to play on the course. Book at the Pro-shop or through Reception. Leisure activities include: a pool; tennis, basketball and volleyball courts; beauty and rejuvenation facilities, including sauna, spa and fitness gym.

We conference in Semillon 3, located in the Main building to the left of the Main entrance as you come in. The Exhibition Suite houses the Exhibition, Demonstrations, Posters and refreshments and is located on the ground floor. Signs/Staff will direct you.

Welcome to the 2015 Hunter Meeting Week!

We are delighted to introduce EMBO Member

Jean Gruenberg presenter of the prestigious EMBO Plenary Lecture in the 2015 Hunter Meeting Week

Since 1999, EMBO Members have been provided with financial support to give plenary lectures at

major international scientific meetings. While the support allows EMBO Members to intensify exchange

and collaboration between scientists from associated fields, it also draws attention to EMBO programmes

and activities within the scientific community worldwide.

EMBO Courses: Biannual selection by a committee of EMBO Members ensures the consistent high quality and novelty of EMBO-funded courses, workshops and conference series. The commitment of the scientific organizers guarantees the long-term success of the programme to inform and train

researchers at all career stages. EMBO runs a series of courses, supports lectures such as Prof Sansonettis at the Hunter Meeting and organises the annual EMBO Meeting.

The EMBO Meeting 20155-8 September, 2015 | Birmingham, UK

www.the-embo-meeting.org/

EMBO events Calendar ( www.embo.org/events ) Lists 2015 supported meetings

The Hunter Meeting Executive and Convenors are grateful for EMBOs continuing support of the Hunter Meetings.

The 2015 Hunter Meeting Week | March 16-20, 2015 | Crowne Plaza Hunter Valley, Lovedale NSW Australia6

ANZSCDB, the Australia and New Zealand Society for Cell and Developmental Biology, promotes Australian and New Zealand activities and international collaborations in the disciplines of Cell and Developmental Biology through: sponsorship of regional, national and international meetings, advocacy with Government, and awarding of the prestigious Presidents Medal and Young Investigator Award.

ANZSCDB is a continuing sponsor of the Hunter Meetings, and in 2015 is delighted to suport the attendance of:

Olivier Pourqui (Professor, Department of Genetics at Harvard Medical School and Professor of

Pathology, Brigham and Womans Hospital)

ANZSCDB State Cell and Developmental Biology Meetings www.anzscdb.org/These meetings are held throughout the year. Check out the ANZSCDB website for updates.

We invite new members to join us in growing the Society and our disciplines of Cell and Developmental Biology. Visit the website for on-line membership and renewals. www.anzscdb.org/

ComBio is the Annual Meeting of the ANZSCDB, held jointly with other Societies. It is also the largest Biological Sciences Meeting in Australasia, and as such attracts prestigious international and national presenters.

There are benefits to Members in terms of reduced fees, poster and ECR Prizes and travel awards.

Join us for the 2015 Annual Meeting of the ANZSCDB Melbourne Convention and Exhibition Centre | 27 September to 1 October, 2015

ANZSCDB

ANZSCDB

With grateful thanks to our generous

Academic and Society Sponsors ...

Imaging Workshop Sponsorsincluding Exhibition...

Charles Perkins Centre

Domonstration booth

Hunter Systems Meeting | 15th Hunter Meeting | 8th National Imaging Workshop | March 16-20, 2015 | 9

... and Exhibitors

Domonstration booth

Our grateful thanks to the Institute of Molecular and Cell Biology - IMCB, Singapore

and International Committee member and Executive Director, Professor Wanjing

Hong, for travel sponsorship of Professor Frederic Bard and Dr Daniel Messershmidt

for attendance at the 2015 Hunter Meetings.

To the newly established Charles Perkins Institute, University of Sydney and

Professor David James, we are grateful for sponsorship of the 2015 Hunter Meeting,

supporting Professor Charlie Boone's attendance and presentation at the meeting.

We are grateful to Australian Regenerative Medicine Institute - ARMI and Monash

University for Sponsorship of Professor Hiroaki Kitano's attendance and presentation

at the 2015 Hunter Meetings, presenting the Keith Stanley Lecture.


POSTER SESSIONS AND ABSTRACT NUMBERS

COMBINED MEETING Posters and Wine with Trade display Hung for the entire meetingExhibition Suite

1 Viral and cellular Tumour Necrosis Factor Receptor (TNFR) interactions and implications for inhibition of TNF and TNFR-related biologyGale, A1, 2, Johnson, M1, 2, McDermott, M3 and Sedger, L1,41 Department of Medical and Molecular Biosciences; 2 iThree Institute: Infection, Immunity & Innovation, The University of Technology Sydney. Sydney, Australia.; 3 Experimental Rheumatology, National Institute for Health Research Leeds, Musculoskeletal Biomedical Research Unit (NIHR-LMBRU) and Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM),University of Leeds, UK; 4 Australian School of Advanced Medicine. Faculty of Medicine& Health Sciences, Macquarie University.

2 Alternations in GLUT4 Storage Compartments Induced by Insulin ResistanceBurchfield, JG1, Fazakerley, DJ1, Hughes, WE2 and James, DE11) SMB, The University of Sydney, D17-Charles Perkins Centre, The University of Sydney, The University of Sydney, New South Wales 2006, Australia; 2) The Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW 2010

3 Using subcellular spatial alignment for live-cell CLEM to investigate mitochondrial degradationRamm, G1, 2, 3, Oorschot, V1, 2, 3 and Padman, B2, 31 Cryo EM Facility / Ramaciotti Centre; 2 Monash Micro Imaging; 3 Department of Biochemistry, Monash University, Building 75, Wellington Road, Clayton, Melbourne, VIC 3800, Australia

4 A photoactivation approach reveals ultra fast internalisation of selected components of the T cell receptor signalling pathway upon activationRother, N, Amiezer, M, Pandzic, E, Nicovich, P, Gaus, K and Rossy, JARC CoE in Advanced Molecular Imaging, University of New South Wales, Sydney, NSW 2052, Australia

5 Phosphorylation regulates distinct mitotic functions of Sorting Nexin 9 (SNX9)Ahmadi-Pirshahid, D1, Ma, M1, Rodriguez, N1 and Chircop, M11-Cell Cycle Unit, Children's Medical Research Institute, 214 Hawkesbury Rd, Westmead, Sydney, NSW 2145, Australia

6 A novel actin filament population that regulates ER-to-Golgi traffickingKee, AJ1, Yang, L1, Polishchuk, E2, Polishchuk, R2, Pleines, I3, Kile, B3, Weigert, R4, Gunning, PW1 and Hardeman, EC11School of Medical Sciences, UNSW Australia, Sydney NSW; 2Telethon Institute of Genetics and Medicine, Naples, Italy; 3Walter and Eliza Hall Institute, Melbourne, VIC; 3Intracellular Membrane Trafficking Unit, Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA

7 Tumour suppressive role of the autophagy pathway in Ras-driven epithelial tumourigenesisManent, J1,2, Banerjee, S1,2, Penninger, JM4, Simpson, KJ3, Humbert, PO2 and Richardson, HE11- Cell Cycle and Development and 2- Cell Cycle and Cancer Genetics laboratories, Peter MacCallum Cancer Centre, Australia; 3- Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Australia; 4- Institute for Molecular Biosciences, Austria

8 Comparison of the role of human PI 3-kinase pathway in internalisation of the bacterial pathogens Yersinia enterocolitica and Listeria monocytogenes Dowd, GC1, Kean, B1, Bhalla, M1, Thomas, R1, Akhmanova, A2 and Ireton, K11. The University of Otago, Dunedin, New Zealand; 2. Utrecht University, The Netherlands

9 The role of Rabs, Rab GAPs and Rab GEFs in insulin actionStoeckli, J, Murrow, BA, D'Souza, RC and James, DECharles Perkins Centre, The University of Sydney, D17 - The Hub, The University of Sydney, Sydney, NSW 2006, Australia

10 Investigating biological roles of Dipeptidyl Peptidase 9 enzyme activity in mice using targeted enzyme inactivationGall, M, Chen, Y, Zhang, H, Hamson, E, Keane, F and Gorrell, MCentenary Institute, Sydney Medical School, University of Sydney, NSW, 2006 Australia

11 Intracellular trafficking dynamics of degraded bone matrix in osteoclastsNg, P1, Tran, AN1, Cheng, TS1 and Pavlos, NJ1Cellular Orthopaedic Laboratory, Centre for Orthopaedic Research, School of Surgery, The University of Western Australia, QEII Medical Centre, M Block Level 2, Nedlands, Perth, WA 6009, Australia

12 Host endoplasmic reticulum COPII proteins control cell-to-cell spread of the bacterial pathogen Listeria monocytogenesGianfelice, A1, Le, PH.B.1, Rigano, LA.1, Saila, S1, Dowd, GC.1, McDivitt, T1, Bhattacharya, N2, Hong, W3, Stagg, SM. 2 and Ireton, K11. Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, Otago 9054, New Zealand; 2. Department of Chemistry and Biochemistry, Florida State University, Fl, USA; 3. Institute of Molecular and Cell Biology, Singapore 138673

13 Cellular ImagingYoung, P, Su, Y, Huynh, M, Kable, E and Braet, FAustralian Centre for Microscopy and Microanalysis, Madsen Building F09, University of Sydney, NSW 2006, Australia

14 Vps74p mediates the Golgi retention of the calcineurin-like phosphoesterase Dcr2pTu, L and Banfield, DDivision of Life Science, The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, Hong Kong nil, Hong Kong, P.R.China

15 Systems Analysis Reveals Unique Cardiogenic Transcriptional Network in Adult Heart FibroblastsNim, HT1,2, Furtado, MB1,2, Costa, MW2, Kitano, H1,2, Rosenthal, NA2 and Boyd, SE1,21. Systems Biology Institute (SBI) Australia, EMBL Australia, Level 1, Building 75, Monash University, Clayton, Melbourne, Vic 3800, Australia; 2. Australian Regenerative Medicine Institute, Level 1, Building 75, Monash University, Clayton, Melbourne, Vic 3800, Australia

16 Dipeptidyl peptidase 9 nautral substrates and a role in cell movement invovling focal adhesion kinase and paxillinZhang, H1, Maqsudi, S1, Stephens, A2, Wadham, C3, McCaughan, G1, Keane, F1 and Gorrell, M11 Molecular Hepatology, Liver Injury and Cancer Group, Centenary Institute and Sydney Medical School, University of Sydney, NSW 2006, Australia; 2 Centre for Cancer Research, MIMR-PHI Institute of Medical Research, 27-31 Wright St, Clayton 3168 Australia; 3 Children Cancer Institute Australia, Lowy Cancer Research Centre. University of New South Wales. Sydney, New South Wales, Australia

17 The Role of Receptor-Mediated Endocytosis of H-ferritin in Induction of NFkappaB-dependent Proinflammatory Signalling in Hepatic Stellate CellsFernandez-Rojo, MA1, Burgess, AG1, Glanfield, A1, Hoang-Le, D1 and Ramm, GA1The Hepatic Fibrosis Group, QIMR Berghofer Medical Research Institute, Brisbane, QLD., Australia


SYSTEMS MEETING Posters and Wine with Trade display Hung Monday and TuesdayExhibition Suite

18 Systematic Identification of Ubiquitin Ligase SubstratesSaunders, D, Iconomou, M, Shearer, R, McKenna, J, Uhl, F and Schaefer, EThe Kinghorn Cancer Centre, Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW 2010, Australia

19 Kinetic modelling reveals missing mechanisms in insulin signalling.Wong, MKL1,2,3, Norris, D1,2,3, Burchfield, JG3, Krycer, JR3, Domanova, W1,2,3, Kuncic, Z1,2 and James, DE3,41, Integrative Systems Lab, Charles Perkins Centre, University of Sydney, Camperdown, NSW 2006, Australia; 2, Institute of Medical Physics, School of Physics, University of Sydney, Camperdown, NSW, 2006, Australia; 3, Metabolic Systems Biology Lab, Charles Perkins Centre, University of Sydney, Camperdown, NSW, 2006, Australia; 4, Sydney Medical School, University of Sydney, Camperdown, NSW, 2006, Australia

20 Generalised Enzyme Kinetics Model for Signalling SystemsWong, MKL1,2,3, Krycer, JR1,2,3, Burchfield, JG3, James, DE3,4 and Kuncic, Z1,21, Integrative Systems Lab, Charles Perkins Centre, University of Sydney, Sydney, NSW 2006, Australia; 2, Institute of Medical Physics, School of Physics, University of Sydney, Sydney, NSW, 2006, Australia; 3, Metabolic Systems Biology Lab, Charles Perkins Centre, University of Sydney, Sydney, NSW 2006, Australia; 4, Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia

21 On measurement models for proliferating lymphocyte dataKan, A1, Pavlyshyn, D1, Marchingo, JM.1, Zhou, JH.S.1, Heinzel, S1, Markham, JF.1, Dowling, MR.1 and Hodgkin, PD.1Immunology, Walter and Eliza Hall Institute, 1G Royal Parade, Parkville, Victoria 3052, Australia

22 Systems analysis of basal and insulin stimulated interactome of eIF4E-4EBP1-4EBP2 reveals novel non-redundant functions for the proteins and novel protein-protein interactions.Chaudhuri, R1,2, Yang, G1,2, Ma, X2, Parker, BL1, 2 and James, DE11Charles Perkins Center, D17 Johns Hopkins Drive, University of Syndey, Sydney, Australia; 2Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, Australia. *Authors contributed equally to this work.

23 Molecular modelling reveals the importance of insulin B-chain C-terminal in binding to its receptorPapaioannou, A1,2, Kuyucak, S1,2, James, D2 and Kuncic, Z1,21. School of Physics, University of Sydney, Sydney, NSW 2006, Australia; 2. Charles Perkins Centre, University of Sydney, Sydney, NSW 2006, Australia

24 Harnessing functional genomics to study the role of microRNAs in cancer chemosensitivityNikolic, I1, Elsworth, B1, Gould, K1, Handoko, Y2, Simpson, K2 and Swarbrick, A1The Garvan Institute and The Kinghorn Cancer Centre, 384 Victoria Street, Sydney, NSW 2010, Australia; Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, East Melbourne, Vic, Australia

25 A comprehensive and systematic analysis of miRNA function in neuroblastoma Dodson, E1, 2, Nikolic, I1, 2, Thomas, D3, Simpson, K3 and Swarbrick, A1, 21. The Kinghorn Cancer Centre & Cancer Research Division, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia; 2. St Vincents Clinical School, Faculty of Medicine, UNSW, Sydney, NSW, Australia; 3. Victorian Centre for Functional Genomics , Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

26 Functional screening of melanoma-associated point mutations using high-content imaging and lentviral over-expression vectorsSkalamera, D1, Stevenson, A1, Ainger, SA2, Rizos, H3, Hayward, NK4, Sturm, RA2,5 and Gabrielli, B11-The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia; 2-Institute for Molecular Bioscience, Melanogenix Group, The University of Queensland, Brisbane, Australia; 3-Australian School of Advanced Medicine, Macquarie University, Sydney, Australia; 4-QIMR Berghofer Medical Research Institute, Brisbane, Australia; and 5-Dermatology Research Centre, The University of Queensland, School of Medicine, Translational Research Institute, Brisbane, Australia.

27 A novel tandem-labelling technique to quantify the proteome-wide impact of signalling pathways on the synthesis of specific proteinsKenney, JW2, Genheden, M2, Johnston, HE2, Manousopoulou, A2, Garbis, SD2, Foster, LE3 and Proud, CG1,2,31. Nutrition & Metabolism, South Australian Health & Medical Research Institute, North Terrace, Adelaide, SA SA5000, Australia; 2. University of Southampton, Southampton, SO17 1BJ, United Kingdom 3. Centre for High Throughput Biology, University of British Columbia, Vancouver, BC, Canada

28 Analyzing insulin-stimulated trafficking events using live cell TIRF microscopyNorris, D1, Krycer, J1, Hughes, W2, Burchfield, J1 and James, D1(1) Charles Perkins Centre, D17, The University of Sydney , Camperdown, Sydney, NSW 2006, Australia; (2) The Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, Sydney, NSW 2010, Australia

29 Using a functional screen to identify lethal microRNAs and their possible methods of actionElsworth, B1, Nikolic, I1, Handoko, Y2, Simpson, K2 and Swarbrick, A11 The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Sydney, NSW, Australia; 2 Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia

CELL MEETING Posters and Wine with Trade display Hung Tuesday -ThursdayExhibition Suite

30 Megakaryocyte released factors thrombin cleave osteopontin to negatively regulate haemopoietic stem cellsHeazlewood, SY1,2,*, Storan, MJ1,2,*, Heazlewood, CK1,2, Williams, B1,2, McQualter, RJ1,3, Reitsma, A1,2, Hatwell-Humble, J1,2, Haylock, DN1,2, Oteiza, A4 and Nilsson, SK1,21 CSIRO - Manufacturing Flagship, Bayview Ave / Ring Rd N, Monash University, Clayton, Melbourne, Victoria, 3800, Australia; 2 Australian Regenerative Medicine Institute, Monash University, Melbourne, Australia; 3 Department of Anatomy and Developmental Cell Biology, Monash University, Melbourne, Australia; 4 Department of Medical Biology, University of Troms, Troms, Norway; *Equal contribution.

31 XFM profiling of the bone marrow to improve our understanding of the microenvironment.Cao, B1,2, Heazlewood, CK1,2, Churches, QI1, James, SA1,3 and Nilsson, SK1 Manufacturing Flagship, CSIRO, Level 3, Building 75, Monash University, Clayton, Melbourne, Victoria 3168, Australia; 2 Australian Regenerative Medicine Institute, Monash University, Melbourne, Australia; 3 XFM Beamline, Australian Synchrotron, Melbourne, Australia.


32 Calpains cleave dysferlin to release a synaptotagmin-like module for the calcium-dependent exocytosis of membrane repairRedpath, GMI1,2, Woolger, N1,2, Lek, A1,2, Piper, A1,2, Lemckert, FA1,2, Greer, PA4, North, KN3 and Cooper, ST1,21. Institute for Neuroscience and Muscle Research, Kids Research Institute, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, NSW 2145, Australia; 2. Discipline of Paediatrics and Child Health, The University of Sydney, NSW 2006, Australia; 3. Murdoch Childrens Research Institute, The Royal Children's Hospital, Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, VIC 3010, Australia; 4. Department of Pathology and Molecular Medicine, Queen's University, Division of Cancer Biology and Genetics, Queen's Cancer Research Institute, Kingston, Ontario K7L 3N6, Canada.

33 The role of retromer in Parkinson's diseaseFollett, J1, Yang, Z1, Bugarcic, A1 and Teasdale, RD1Institute for molecular bioscience, University of Queensland, 306 carmody Road, St Lucia, Brisbane, QLD 4072, Australia

34 Cancer-associated PTEN mutants act in a dominant negative manner to suppress PTEN protein functionPapa, APrevious affiliation: Beth Israel Deaconess Medical Center/ Harvard Medical School, Boston, MA, USA. Present address: Department of Biochemistry and Molecular Biology, Monash University, Wellington Road, Melbourne, VIC 3800, Australia

35 Ubiquitin mediated recruitment of BLM helicase to the sites of DNA damage is required to suppress exacerbated homologous recombinationTikoo, S1,3,4, Madhavan, V1,3,4, Hussain, M1, Miller, ES 2, Arora, P1, Zlatanou, A2, Modi, P1, Townsend, K2, Stewart, GS2 and Sengupta, S11. Signal Transduction Lab-2, National Institute of Immunology, New Delhi, India; 2. School of Cancer Sciences, University of Birmingham, Birmingham, United Kingdom; 3. Centenary Institute of Cancer Medicine and Cell Biology,Australia; 4. Sydney Medical School, University of Sydney, Australia

36 An animal model to explain the epidemiological link between sleep aponea and sporadic Alzheimer's diseaseQian, L1, Marks, N1, Shamra, A1, Bellingham, MC2 and Coulson, EJ 11. Queensland Brain Institute, 2. School of Biomedical Sciences, The University of Queensland, Brisbane, Qld 4072, Australia

37 The Neogenin ligand, RGMa, is Required for Adherens Junction AssemblyFok, K, Lee, N, White, A and Cooper, HQueensland Brain Institute, Building 79, Research Lane, St Lucia, Brisbane, Queensland 4072, Australia

38 The guidance receptor neogenin maintains adherens junction integrity by promoting assembly of the actin cytoskeleton Lee, N, Fok, K, White, A, Cox, H and Cooper, HQueensland Brain Institute, University of Queensland, Brisbane, Australia

39 CSF-1 stimulation of macrophage invasionSullivan, AR1, Greenland, EL1 and Pixley, FJ1School of Medicine and Pharmacology, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009, Australia

40 Alternative lengthening of telomeres: controlling crossoverSobinoff, AP.1, Allen, JA.M.1, Cao, Y2, Brygula, ME.1, Reddel, RR.2,3 and Pickett, HA.1,2,31 Telomere Length Regulation Group, Childrens Medical Research Institute, Westmead, New South Wales, Australia; 2 Cancer Research Unit, Childrens Medical Research Institute, Westmead, New South Wales, Australia; 3 Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia

41 A neurogenic perspective of sarcopenia and ageingNambiar, V1, Shavlakadze, T1, Hodgetts, SI1, Harvey, AR1 and Grounds, MD1School of Anatomy Physiology and Human Biology, University of Western Australia, 35 Stirling Highway, Crawley, Perth, Western Australia 6009, Australia

42 Understanding fat storage: the role of SEIPIN in adipogenesis and lipid droplet expansionYang, H1School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Gate 9, High Street, Sydney, NSW 2052, Australia

43 Characterisation of telomere replication in cancer cells using fibre-FISH Allen, JAM1, Sobinoff, AP1, Cesare, AJ2 and Pickett, HA11 Telomere Length Regulation Group, Childrens Medical Research Institute, Westmead, New South Wales, Australia; 2 Genome Integrity Group, Childrens Medical Research Institute, Westmead, New South Wales, Australia

44 Identification of two novel functional domains in Las17p/WASP: a key regulator of the cortical actin cytoskeleton conserved from yeasts to humansHahn, MA, Trinh, AV and Munn, ALSchool of Medical Science and Menzies Health Institute Queensland, Griffith University (Gold Coast Campus), Rm 2.23, Building G05, Parklands Drive, Southport, QLD 4222, Australia.

45 An E-cadherin-FRAP biosensor mouse reveals novel, disease and drug-dependent, dynamic regulation of cell-cell junctions in live tissue Erami, Z1, Herrmann, D2, Nobis, M1, McGhee, E1, Reischmann, N2, Conway, JRW2, Magenau, A2, Gallego-Ortega, D2,3, Anderson, KI1,*,# and Timpson, P2,3,*,#1 Beatson Institute of Cancer Research, Switchback Road, Bearsden, Glasgow, UK; 2 Cancer Division, The Garvan Institute of Medical Research, The Kinghorn Cancer Centre, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia; 3 St Vincents Clinical School, Faculty of Medicine, University of NSW, Australia. * These authors contributed equally. # Corresponding authors.

46 Depdc5 loss of function mice generated by CRISPR-Cas9 mutagenesis are embryonic lethal, while heterozygotes are viableHughes, JN1, Piltz, S1, McAninch, D1 and Thomas, PQ11. Biochemistry, Adelaide Uni, Molecular Life Sciences, Gate 8 Victoria Drive, Adelaide, Adelaide, SA 5005, Australia

47 Mechanism of TRPV4 SensationBaratchi, S1, Almazi, JG1, Darby, W1, Mitchell, A2 and McIntyre, P11School of Medical Sciences, RMIT University, Plenty Road, Bundoora, Melbourne, Victoria 3083, Australia; 2Microplatforms Research Group, School of Electrical and Computer, RMIT University, VIC 3083, Australia

48 Molecular Signatures and Morphology at the Trunk to Tail Transition require microRNA-196 activityCasanova, JC1, Agarwal, V1, Mansfield, JH4,5, Wong, S1, Schwartz, MG4, Prosser, HM6, Bartel, DP2,3, Tabin, CJ4 and McGlinn, E1,41 Australian Regenerative Medicine Institute, Monash University, Level 1, Building 75, Monash University, Clayton, Vic 3800, Australia; 2 Howard Hughes Medical Institute and Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA. 3 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; 4 Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; 5 Barnard College, Department of Biological Sciences, 1306 Altschul Hall, 3009 Broadway, New York, NY, 10027; 6 The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

49 A single-molecule view of assembly pathways underlying the functional specialisation of the actin cytoskeletonObeidy, P1, 2, Pandzic, E1, 2, Sobey, T1, Sobey, T1, Nicovich, PR.1, Coster, A3, Gunning, P2 and Bcking, T11Single Molecule Science and ARC Centre of Excellence in Advanced Molecular Imaging, UNSW, Sydney, Australia. 2School of Medical Sciences, UNSW, Sydney, Australia. 3School of Mathematics & Statistics, UNSW Sydney, NSW, Australia


Monday 16th March, 2015

Inaugural HUNTER SYSTEMS MEETINGCrown Plaza Hunter Valley

09:00 Sydney Airport Coach departs for Crowne Plaza Hunter Valley

Hertz Rental Counter (inside) T3, Qantas Domestic Terminal Sydney Airport

09:00 Full Hunter Meeting and Systems Meeting Exhibitors set-up

Exhibition Suite, Crowne Plaza, Hunter Valley

12:00 Airport Coach arrives at Crowne Plaza, Hunter Valley

Reception, Crowne Plaza Hunter Valley

12:00 - 12:30 Lunch with the Exhibition

Exhibition Suite, Crowne Plaza, Hunter Valley

12:30 - 14:20 Session 1: Proteomics and Protein Networks

Semillon Room 3

Chair: Marc Wilkins

12:30 50 Metabolic CyberneticsJames, DECharles Perkins Centre, The University of Sydney, D17 - Charles Perkins Centre, The University of Sydney, NSW 2006, Australia

13:00 51 Computing variability in the structure of molecular networks and the impact on information transduction in biological systemsDavis, MElectrical and Electronic Engineering, The University of Melbourne, Level 2, Building 193, The University of Melbourne, Parkville, Melbourne, VIC 3010, Australia

13:20 52 Protein Complex Dynamics in Response to Acute StarvationLarance, M1, Pourkarimi, E1, Wang, B1, Gartner, A1 and Lamond, A1Gene Regulation and Expression, University of Dundee, WTB/CLS, University of Dundee, Dow St, Dundee, Angus DD1 5EH, United Kingdom

13:40 53 An integrative network approach for neurodevelopmental geneticsYao, P1, Gokoolparsadh, A1, Assareh, A1, Thang, M2 and Voineagu, I1UNSW - The University of New South Wales, High St, Kensington, NSW 2052, Australia; The University of Queensland

14:00 54 The Saccharomyces cerevisiae intracellular methylation networkHart-Smith, G1 and Wilkins, MR1School of Biotechnology and Biomolecular Sciences, UNSW - The University of New South Wales

14:20 - 15:00 Exhibition | Tea | PostersExhibition Suite

15:00 - 16:50 Session 2: Computational Biology, Modelling, enabling Technologies

Semillon Room 3

Chair: Sarah Boyd

15:00 55 Integrative genomics of cardiovascular diseaseMakinen, VV-PSAHMRI-South Australian Health and Medical Research Institute, North Terrace, Adelaide, South Australia 5000, Australia

15:30 56 Modelling Biological Complexity and Information FlowKuncic, Z1Charles Perkins Centre, University of Sydney, Sydney, NSW 2006, Australia

15:50 57 Regulation of articular cartilage extracellular matrix turnoverGardiner, BS1 , Zhang, L1 , Kar, S1, Woodhouse, FG1, Grodzinsky, AJ3 and Smith, DW11. The University of Western Australia, Crawley, Western Australia 6009, Australia; 2. University of Melbourne, Parkville, Victoria 3010, Australia; 3. Massachusetts Institute of Technology, Massachusetts, USA

16:10 58 Dynamic models of the JNK signalling network predict neuroblastoma patient outcome.Fey, D1, Halasz, M1, Kolch, W1, Kholodenko, BN1 and Croucher, DR1,2,31: Systems Biology Ireland, University College Dublin, Dublin, Ireland 2: The Kinghorn Cancer Centre, Garvan Institute of Medical Research, NSW, 2010 3: St Vincent's Hospital Clinical School, University of New South Wales, Sydney, NSW 2052, Australia.

16:30 59 Cellular Control of Cortical Actin Nucleation and AssemblyBiro, M1,2, Bovellan, M1,2, Romeo, Y4,5, Kroschwald, S1, Boden, A1,6, Tcherkezian, J4, Roux, PP4, Charras, G3 and Paluch, EK1,71: Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany; 2: Cellular Mechanobiology, Immune Imaging Program, Centenary Institute of Cancer Medicine and Cell Biology, Sydney, Australia; 3: London Centre for Nanotechnology, UCL, London, UK; 4: Institute for Research in Immunology and Cancer, Universit de Montral, Montreal, Canada; 5: Laboratoire de Biologie Molculaire Eucaryotes, CNRS, Universit de Toulouse, Toulouse, France; 6: B Cube Centre for Molecular Bioengineering, Technische Universitt Dresden, Dresden, Germany; 7: MRC Laboratory for Molecular Cell Biology, UCL, London, UK

16:50 - 17:00 Bio-Break

17:00 - 18:00 Session 3: Plenary 1: Systems Keynote Lecture:

Charles Boone, University of Toronto

Chair: David James

17:00 60 Modeling the Cell with a Global Genetic Interaction NetworkBoone, CDonnelly Centre, University of Toronto, Donnelly Centre 160 College St, Toronto, ON M5S 3E1, Canada

18:30 - 20:00 Dinner

Wine on the tables, then cash bar West Terrace and the Gallery

20:00 - 22:00 Session 4: Posters and Wine with Trade display

Exhibition Suite

Charles Perkins Centre


Tuesday 17th March, 201507:00 Breakfast

Red Salt Restaurant

08:15 Arrival Tea & CoffeePre Function Lobby

09:00 Sydney Airport Bus departs for Crowne Plaza Hunter Valley

Hertz Rental Counter (inside) T3, Qantas Domestic Terminal Sydney Airport

08:30 - 10:20 Session 5: Human variation

Semillon Room 3

Chair: Paul Gleeson

08:30 61 The MitoExome and Mitochondrial DiseaseThorburn, DRGenetics Research Theme, Murdoch Childrens Research Institute, 50 Flemington Rd, Parkville, Melbourne, VIC 3052, Australia

08:55 62 Phenotypic subclassification of human cancers through phosphoproteomic and kinomic profilingDaly, RJDepartment of Biochemistry and Molecular Biology, Monash University, Level 1, Building 77, Monash University, Clayton, VIC 3820, Australia

09:15 63 Determining mechanisms of genetic susceptibility underlying human diseasePowell, JCentre for Neurogenetics and Statistical Genomics, Queensland Brain Institute, QBI, UQ St Lucia, Brisbane, Qld 4072, Australia

09:35 64 Unbiased multidimensional, cytological profiling of Parkinsons disease patient cells to identify biomarkers.Vial, M1, Murtaza, M1, Tran, T1, Gorse, A2, Mellick, GD1, Quinn, RJ1 and Wood, SA11. Eskitis Institute for Drug Discovery, Griffith University, Brisbane Innovation Park, N75 Don Young Road, Nathan, Brisbane, QLD 4111, Australia; 2. QFAB Bioinformatics, University of Queensland, St Lucia, QLD 4072, Australia

10:05 Open discussion

10:20 - 11:00 Exhibition | Coffee | PostersExhibition Suite

11:00 - 12:50 Session 6: Systems approaches to chronic and infectious diseases

Semillon Room 3

Chair: Graham Mann

11:00 66 Simultaneous transcriptional profiling of bacteria and their host cellsMyers, GThe ithree Institute, University of Technology, Sydney, Cnr Harris and Thomas Streets Ultimo, Sydney, NSW 2007, Australia

11:25 67 Integration of melanoma omics data to find its real driversMann, GCentre for Cancer Research, Westmead Millennium Institute and Melanoma Institute Australia, University of Sydney, 176 Hawkesbury Rd, Westmead, NSW 2145, Australia

11:50 68 Unravelling the dynamic molecular mechanisms of insulin signallingDomanova, W1,2, Krycer, J1,2, Chaudhuri, R1, Vafaee, F1, James, D1 and Kuncic, Z1,21 University of Sydney, D17 Charles Perkins Centre, The University of Sydney, Camperdown, Camperdown, New South Wales 2006, Australia; 2 School of Physics, University of Sydney, Sydney, NSW 2006, Australia

12:10 69 Viral inflammatory diseases: New insights into disease mechanisms, therapeutic approaches and human studiesMahalingam, SInstitute for Glycomics, Griffith University, Gold Coast campus, Parklands Drive, Southport, QLD 4215, Australia

12:30 70 Analysing Tandem Repeats by High Throughput SequencingGanesamoorthy, D1, Cao, M1 and Coin, L1Institute for Molecular Bioscience, The University of Queensland, 306 Carmody Road, Brisbane, Brisbane, Not Applicable 4068, Australia

HUNTER CELL MEETING begins - Combined Systems and Cell Sessions

12:50 - 13:50 Exhibition | Lunch | PostersExhibition Suite

13:50 - 15:50 Session 7: Cell based screens

Semillon Room 3

Chair: Kaylene Simpson

13:50 71 Golgi-X: mapping the genetic networks regulating the Golgi apparatusBard, FInstitute of Molecular and Cell Biology, 61, Biopolis Drive, Singapore, Singapore 138673, Singapore

14:40 72 Restoring E-cadherin mediated cell-cell adhesion in colorectal cancer cellsKing, LE1, Simpson, KJ1, Faux, MC1 and Burgess, AW11 Structural Biology, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Melbourne, VIC 3052, Australia; 2 Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, East Melbourne, VIC 3002, AUSTRALIA


14:55 73 Systematic screening identifies dual PI3K and mTOR inhibition as a conserved therapeutic vulnerability in osteosarcomaWalkley, CR11 St Vincent's Institute of Medical Research, 9 Princes St, Fitzroy, Victoria 3065, Australia

15:15 74 A comprehensive and systematic analysis of microRNA function in cancerNikolic, I1,2, Dodson, E1,2, Thomas, D3, Yang, J1, Simpson, K3 and Swarbrick, A1,2The Kinghorn Cancer Centre & Cancer Research Division, Garvan Institute, 384 Victoria st, Darlinghurst, Sydney, NSW 2010, Australia; St Vincent's Clinical School, Faculty of Medicine, UNSW, Australia; Victorian Cenrre for Functional Genomics, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia

15:35 75 Investigating the mechanism underlying the nucleolar stress response and its role in diseaseGeorge, AJ1,3,4,5, Wong, MS1,3,4,5, Al-Obaidi, S1, Gould, CM3, Madhamshettiwar, P3, Simpson, KJ2,3,4, Pearson, RB1,2,6,7 and Hannan, RD1,2,5,6,71 Oncogenic Signalling and Growth Control Program, Peter MacCallum Cancer Centre, East Melbourne, Victoria, 3002, Australia; 2 Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, 3010, Australia; 3 The Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, East Melbourne, Victoria, 3002, Australia; 4 Department of Pathology, The University of Melbourne, Parkville, Victoria, 3010, Australia; 5 School of Biomedical Sciences, The University of Queensland, St Lucia, Queensland, 4072, Australia; 6 Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, Victoria, 3010, Australia; 7 Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, 3800, Australia.

15:50 - 16:30 Exhibition | Afternoon Tea | PostersExhibition Suite

16:30 - 18:30 Session 8: Biological Systems

Semillon Room 3

Chair: David James

16:30 76 Quantitative determinants of glucose and amino acid metabolismLocasale, JCornell University, Savage Hall 108, Ithaca, NY 14850, USA

17:30 77 Multiscale cardiac modelling reveals the molecular origins of ECG waveforms in health and diseaseHill, AComputational Cardiology, VCCRI, 405 Liverpool Street, Darlinghurst, NSW 2226, Australia

17:50 78 A Systems Microscopy approach to mapping Plasticity in the Cell Migration SystemLock, JG, Shafqat, H, Berge, U, Hernandez-Varas, P, Mamaghani, M, Kowalewski, J, Kiss, A, Gong, X and Stromblad, SBiosciences and Nutrition, Karolinska Institute, Halsovagen 7-9, Huddinge, Stockholm 14183, Sweden

18:10 Open discussion

18:30 - 20:00 Welcome Drinks and Bar-B-Q DinnerThe 1st Tee

20:00 - 21:00 Session 9: Plenary 2: The Keith Stanley Lecture:

Hiroaki Kitano, OIST, Japan

Chair: Roger Daly

20:00 80 The Day AI Wins Nobel Prize: Toward Advanced Intelligence that Transforms the Way We do Biomedical ResearchKitano, HRIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama City, Kanagawa 230-0045, Japan


Exhibition Suite

NOTES


Wednesday 18th March, 201507:00 Breakfast

Red Salt Restaurant

08:15 Arrival Tea & CoffeePre Function Lobby

09:30 Airport Bus departs Crowne Plaza for Sydney Airport.

Collect take-away Morning Tea from Pre-Function Lobby

Pre Function Lobby

8:30 - 10:00 Session 11: Organelle Focus - Mitochondria

Semillon Room 3

Chair: Mike Ryan

08:30 81 Mitochondrial behaviorNunnari, JUniversity of California, Davis, One Shields Avenue , Davis, CA 95616, USA

09:55 82 The role of mitochondrial RNA-binding proteins in health and diseaseFilipovska, A1,21 Harry Perkins Institute of Medical Research, Level 7, QQ Block, QEII Medical Research Centre, 6 Verdun Street, Nedlands, WA 6009, Australia; 2 School of Chemistry and Biochemistry, The University of Western Australia, Crawley 6009 WA Australia

09:25 83 Increasing mitochondrial NAD biosynthesis improves metabolismBentley, N1, Montgomery, M1, Fiveash, C1, Polly, P2 and Turner, N11. Mitochondrial Bioenergetics Laboratory, Department of Pharmacology, School of Medical Sciences, UNSW - The University of New South Wales, High St, Kensington, NSW 2228, Australia; 2. Inflammation and Infection Research Centre, Department of Pathology, School of Medical Sciences, UNSW - The University of New South Wales, High St, Kensington, NSW 2228, Australia

09:45 84 Repertoire of autophagy adaptor function during PINK1/Parkin mediated mitophagyLazarou, MDepartment of Biochemistry and Molecular Biology, Monash University, Clayton, Australia


10:40 - 12:10 Session 12: Regeneration

ANZSCDB Lecture: Olivier Pourqui

Semillon Room 3

Chair: Edwina McGlinn

10:40 85 Development of the musculo-skeletal axisPourqui, OHarvard Medical School Brigham and Women's Hospital, Divinity Avenue, Cambridge, MA 02138, USA

11:15 86 Immune regulation of regenerationRosenthal, NARMI Monash University, Level 1, Building 75, Wellington Road, Clayton, Melbourne, Victoria 3800, Australia

11:35 87 Questioning the premise for stem cell therapy to enhance old muscle regeneration and alleviate sarcopenia Grounds, MDSchool of Anatomy & Human Biology, The University of Western Australia, 35 Stirling Hwy, Crawley, Perth, WA 6009, Australia

11:55 88 Metabolism and growth signals activate stem cell quiscence in regenerating zebrafish tissuesColquhoun, D, Lindsey, B and Kaslin, JAustralian Regenerative Medicine Institute, Monash University, Wellington road, Building 75,

Melbourne, VIC 3800, Australia


8th NATIONAL IMAGING WORKSHOP

13:10 - 14:40 Session 13: Imaging Workshop I

Semillon Room 3

Chair: Jenny Stow

13:10 89 Multiscale electron microscopy: application in the study of membrane microdomainsParton, RG. Institute for Molecular Bioscience, University of Queensland, Queensland Biosciences Precinct, St Lucia, Brisbane, QLD 4072, Australia

13:40 90 Imaging the CD8+ T cell response to Plasmodium in the lymph nodes and liverCockburn, IAJohn Curtin School of Medical Research, The Australian National University, 131 Garran Road, Acton, ACT 2601, Australia

13:55 91 Multiphoton imaging of leukocyte dynamics in vivo in the kidney and skinHickey, MJCentre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical Centre, Clayton, VIC 3168, Australia.

ANZSCDB


14:10 92 Understanding the dynamics of leukocyte sequestration during cerebral malaria pathogenesis.Jain, R1,2, Pai, S1,2, Mitchell, A1,2, Tikoo, S1,2, Hickey, M3, Hunt, N2,4, McMenamin, P5, Grau, G2,6 and Weninger, W1,7,81The Centenary Institute, Newtown, NSW 2042, Australia; 2Sydney Medical School, NSW 2006, Australia; 3Monash University Department of Medicine, Monash Medical Centre, VIC 3168, Australia; 4Molecular Immunopathology Unit, Discipline of Pathology, Sydney Medical School and Bosch Institute, NSW 2006, Australia; 5Department of Anatomy & Developmental Biology, Monash University, Clayton, VIC 3800, Australia; 6Vascular Immunology Unit, Discipline of Pathology, Sydney Medical School, NSW 2006, Australia; 7 Discipline of Dermatology, Sydney Medical School, NSW 2006, Australia; 8 Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia.

14:25 2 Alternations in GLUT4 Storage Compartments Induced by Insulin ResistanceBurchfield, JG1, Fazakerley, DJ1, Hughes, WE2 and James, DE11) SMB, The University of Sydney, D17-Charles Perkins Centre, The University of Sydney, The University of Sydney, New South Wales 2006, Australia; 2) The Garvan Institute of Medical Research, 384 Victoria St, Darlinghurst, NSW 2010

14:40 - 15:20 Exhibition | Tea | Posters Exhibition Suite

15:20 - 16:20 Session 14: Workshop 2: Imaging Workshop II

Semillon Room 3

Chair: Wolfgang Weninger

15:20 93 Temporal regulation of T cell priming during peripheral infectionHor, J1, 2, Heath, WR1, 2 and Mueller, SN1, 21 Dept. Microbiology & Immunology, and the Peter Doherty Institute, The University of Melbourne, Parkville, VIC 3010, Australia; 2 ARC Centre of Excellence in Advanced Molecular Imaging.

15:35 94 Immune cell migration, function and fate uncovered using two-photon microscopy and in vivo photoconversionChtanova, TGarvan Medical Research Institute, 384 Victoria street, Darlinghurst, NSW 2010, Australia

15:50 95 Imaging the diffusive route of transcription factor activity in live cells by fluctuation analysisHinde, E1, Pandzic, E1, Gratton, E2 and Gaus, K11. School of Medical Sciences, The University of New South Wales, Sydney, Australia. 2. Laboratory for Fluorescence Dynamics, University of California, Irvine. USA.

16:05 Whats new at molecular probesEl-Hoss, JLife Technologies

16:20 - 16:30 Bio Break and Sponsored DrinksSemillon Room 3

16:30 - 17:15 Session 15: Plenary 4: Imaging Plenary Lecture:

Hans-Ulrich Dodt, Bioelectronics - Medical University of Vienna, Austria

Semillon Room 3

Chair: Wolfgang Weninger

16:30 96 Light sheet microscopy of cleared mouse brains, embryos and cancer Dodt, H-U Department of Bioelectronics, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, Vienna, A-1090 , Austria

17:15 - 17:20 Bio BreakSemillon Room 3

17:20 - 18:20 Session 16: Plenary 5: Hunter Plenary Lecture:

Sharad Kumar, Centre for Cancer Biology, SA

Semillon Room 3

Chair: Rohan Teasdale

17:20 97 Mechanisms and regulation of programmed cell death: Lessons from the humble flyKumar, SCentre for Cancer Biology, University of South Australia, c/o SA Pathology, Frome Road, Adelaide, SA 5000, Australia

18:30 - 20:00 Dinner: a Drink on arrival, then cash bar

Since we are not the only group in The Lovedale Bar and Restaurant, you will be given a wristband on arrival (just like the Clubbers!)

The Lovedale


Exhibition Suite

NOTES


Thursday 19th March, 201507:00 Breakfast

Red Salt Restaurant

08:15 Arrival Tea & Coffee

Pre Function Lobby

08:30 - 10:30 Session 18: Intracellular Trafficking

Semillon Room 3

Chair: Rob Parton

08:30 98 Receptor localisation shapes the spatiotemporal dynamics of GPCR signallingCanals, M, Halls, ML and Bunnett, NWDrug Discovery Biology, Monash Institute of Pharmaceutical Sciences, 399 Royal Parade, Parkville, Melbourne, Vicotria 3052, Australia

08:50 99 Sorting Nexin 27 Regulates Agonist-dependent Trafficking of the Parathyroid Hormone Receptor for Bone Growth and MetabolismPavlos, N11, Cellular Orthopaedic Laboratory, School of Surgery, The University of Western Australia, Nedlands, Western Australia 6009

09:10 100 Chlamydia selectively subverts host cell trafficking pathways to facilitate intracellular growth and infection.Kerr, MC1 and Teasdale, RD11) Institute for Molecular Bioscience, The University of Queensland, 306 Carmody Road, St. Lucia, Brisbane, QLD 4072, Australia

09:30 101 Molecular Sensors to Understand Cellular TraffickingJohnston, APR1 and Liu, H1Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, 381 Royal Parade, Parkville, Melbourne, Victoria 3052, Australia

09:50 102 Selectively, sensitivity and auto-inhibition in motor-cargo recognitionSanger, A, Pernigo, S, Yip, Y, Steiner, RA and Dodding, MPRandall Division of Cell and Molecular Biophysics, King's College London

10:10 103 Endosomal sorting of -Secretase, BACE1, and Alzheimers disease Toh, W1, Chia, PCheryl1 and Gleeson, PA1Department of Biochemistry and Molecular Biology and Bio21 Mole, University of Melbourne, 30 Flemington Road, Melbourne, VIC 3010, Australia


11:10 - 12:40 Session 19: Organisation of Cell Signalling and Gene Expression

Semillon Room 3

Chair: Carol Wicking

11:10 104 Epigenetic Memory Loss in the Early EmbryoMesserschmidt, DDevelopmental Epigenetics and Disease, Institute of Molecular & Cell Biology, A*STAR, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore

11:45 105 Regulation of phosphoinositide signalling at ciliaMitchell, CA, Dyson, J and Conduit, SDepartment of Biochemistry and Molecular Biology, Monash University, Wellington Road, Clayton, Melbourne, Victoria 3800, Australia

12:05 106 Prion-like domains in RNA binding proteins are essential for building subnuclear paraspecklesFox, AHDr, Hennig, SDr, Bond, CProf and Hirose, TProfCancer Gene Regulation, Harry Perkins Institute of Medical Research, The University of Western Australia, Crawley, WA 6009, Australia

12:25 107 Novel mechanisms of regulation of nuclear import in cancer - targets for therapeutics ?Jans, DADBMB, Monash University, c/- DBMB Building 77 Room 146 Monash Uni, Monash, Melbourne, VIC 3800, Australia


13:10 - 16:00 Session 20: Workshop 3: Imaging Workshop Demonstration

Exhibition Suite

Demonstrations and Exhibition | Tea served

15:45 Remove Posters

Exhibition Suite

16:15 - 17:30 Exhibitor pack-down

Exhibition Suite

NOTES


16:00 - 17:30 Session 21: Cellular polarity and tissue organisation

Semillon Room 3

Chair: Patrick Humbert

16:00 108 Elucidation of T cell fate control by time lapse imaging and quantitative microscopy.Russell, SImmune Signalling Laboratory, Cancer Immunology Division, Peter MacCallum Cancer Institute, St Andrews Place, East Melbourne, VIC 3002, Australia

16:25 109 Feedback control Yap, A, Priya, R, Hamilton, N and Gomez, GInstitute for Molecular Bioscience, University of Queensland, 306 Carmody Road, St. Lucia, Brisbane, QLD 4072, Australia

16:50 110 In situ identification of bipotent stem cells in the mammary glandRios, AC, Fu, N, Lindeman, GJ and Visvader, JEStem cell and cancer, Walter and Eliza Institute, 1G Royal parade, Parkville, Melbourne, VIC 3052, Australia

17:10 111 Dissecting principles governing actin assembly with biomimetic systemsGressin, L1, Planade, J1, Guillotin, A1, Guerin, C1, Blanchoin, L1, du Roure, O2, Heuvingh, J2 and Michelot, A11 Laboratoire de Physiologie Cellulaire et Vgtale, Institut de Recherches en Technologies et Sciences pour le Vivant, Centre National de la Recherche Scientifique/Commissariat lEnergie Atomique et aux nergies alternatives/Institut National de la Recherche Agronomique/Universit Joseph Fourier, Grenoble, France; 2 Physique et Mcanique des Milieux Htrognes, cole Suprieure de Physique et Chimie Industrielle de la ville de Paris, Centre National de la Recherche Scientifique, Universit Pierre et Marie Curie, Universit Paris Diderot, Paris, France

17:30 - 17:40 Bio BreakSemillon Room 3

17:40 - 18:40 Session 22: Plenary 5: EMBO Plenary Lecture:

Professor Jean Gruenberg

Semillon Room 3

Chair: David James

17:30 112 Endosomal lipids in trafficking and signalingGruenberg, JBiochemistry Department, University of Geneva, Department of Biochemistry, 30 quai E. Ansermet, Geneva, Geneva, Geneva/Switzerland 1211, Switzerland

19:00 - 22:00 Conference Dinner. Wine on the tables, then cash barThe Pergola

Friday 20th March, 201507:00 Breakfast and check out. Stow luggage wih Concierge

Red Salt Restaurant

08:15 Arrival Tea & Coffee

Pre Function Lobby

08:30 - 10:25 Session 23: Neuronal Development and Degeneration

Semillon Room 3

Chair: Lizzie Coulson

08:30 113 Structural biology of p75 neurotrophin receptor signalingIbanez, CNeuroscience | Physiology, Karolinska Institute | National University of Singapore, Berzelius vag 35 | 28 Medical Drive, Stockholm | Singapore, n.a. 17177 | 117456, Sweden | Singapore

09:15 114 Neogenin: a new determinant of wave-mediated actin nucleation and adherens junction assembly in neural stem cellsCooper, HM1, Lee, NK1, Nourse, C1, Cox, H1, Foc, K1, White, A1 and O'Leary, C11. Queensland Brain Institute, University of Queensland, St Lucia, Brisbane, QLD 4072, Australia

09:35 115 Two forms of dynamin I and II suggest new rolesRobinson, P and Collett, MCell Signalling Unit, Children's Medical Research Institute, 214 Hawkesbury Road, Westmead, Sydney, NSW 2145, Australia

09:55 116 APP regulates hippocampal neurogenesis in adulthoodWang, S1, Bolos, M1, Southam, K1, Roberts-Thompson, M1, Foa, L2, Small, DH1 and Young, KM 11 Menzies Institute for Medical Research, The University of Tasmania, 17 Liverpool Street, Hobart, Tasmania 7000, Australia; 2 The School of Medicine, The University of Tasmania, 17 Liverpool Street, Hobart, Tasmania 7000, Australia

10:10 117 Neuronal development in tumors: a novel promoter of cancer progression.Jobling, P1, Roselli, S1, Pundavela, J1, Faulkner, S1, Oliveira, SMR1, Demont, Y2, Walker, MM1, Bradshaw, RA3 and Hondermarck, H11) Hunter Medical Research Institute, The University of Newcastle, Callaghan, NSW 2308, Australia; 2) INSERM U872, Centre de Recherche des Cordeliers, 75006 Paris, France; 3) Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158, USA

10:25 - 10:55 CoffeePre-Function Lobby

NOTES


10:55 - 12:25 Session 24: Therapeutics and Disease Models

Semillon Room 3

Chair: Peter Gunning

10:55 118 In vivo imaging of pharmacodynamics in breast and pancreatic cancer using FLIM-FRETNobis, M1, Hermann, D1, McGhee, E1, Blyth, K1, Welch, H2, van Rheenen, J3, Strathdee, D3, Sansom, O1, Timpson, P4 and Anderson, K11 Tumour Cell Mirgation, CRUK Beatson Institute for Cancer Research, Glasgow, United Kingdom; 2 The Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom; 3 Hubrecht Institute, Utrecht, The Netherlands; 4 Garvan Institute, Sydney, Australia

10:55 119 Small Molecule 91/41 Integrin Antagonist Mobilisation of Haemopoietic Stem Cells with Long-Term Multilineage Engraftment PotentialCao, B1, Zhang, Z1, Grassinger, J2, Williams, B1, Alexander, WS3, Papayannopoulou, T4 and Nilsson, SK11 CSIRO/Monash University, Building 75, Monash University, Wellington Rd, Melbourne, Vic 3168, Australia; 2 University Hospital Regensberg, Department of Haematology and Oncology, Regensburg, Germany; 3 Walter and Eliza Hall Institute, Royal Parade, Parkville, VIC 3052, Australia 4 Department of Medicine/Haematology, University of Washington Seattle, WA, USA

11:20 120 CRISPR-mediated gene tagging, mutation and disease modeling in miceBowles, J, Quinn, A, Zhao, L and Koopman, PInstitute for Molecular Bioscience, University of Queensland, Carmody Rd, St Lucia, Brisbane, QLD 4072, Australia

11:40 121 Altered endosome biology in prostate cancer identifies potential biomarkers for patient diagnosis and prognosisJohnson, IRD1, Parkinson-Lawrence, EJ1, Butler, L2, O'Leary, JJ3 and Brooks, DA11. Mechanisms in Cell Biology and Diseases Research Group, School of Pharmacy and Medical Sciences, Sansom Institute for Health Research, University of South Australia, Adelaide SA 5001, Australia; 2. University of Adelaide, Adelaide SA 5005, Australia; 3. Trinity College Dublin/St James Hospital Dublin, Ireland.

12:25 - 12:30 Conference close and announcement of the 2016 Hunter Meeting Week

Semillon Room 3

12:30 Boxed, take Away LunchCollect from Pre Function Lobby

13:00 Coach departs for Sydney Airport

Reception, Crowne Plaza Hunter Valley

2016 Hunter Meeting Week

2016 | March 13-17

AUTHOR INDEXAgarwal, V ....................................................... 48Ahmadi-Pirshahid, D ....................................... 5Ainger, SA ....................................................... 26Akhmanova, A ................................................... 8Alexander, WS .............................................. 119Allen, JAM ................................................ 43, 40Almazi, JG ....................................................... 47Al-Obaidi, S ..................................................... 75Amiezer, M ........................................................ 4Anderson, K .................................................. 118Anderson, KI ................................................... 45Arora, P ........................................................... 35Assareh, A ....................................................... 53Banerjee, S ....................................................... 7Banfield, D ....................................................... 14Baratchi, S ..................................................... 47Bard, F ............................................................ 71Bartel, DP ........................................................ 48Bellingham, MC ............................................... 36Bentley, N ........................................................ 83Berge, U .......................................................... 78Bhalla, M ........................................................... 8Bhattacharya, N .............................................. 12Biro, M ............................................................ 59Blanchoin, L ....................................................111Blyth, K .......................................................... 118Boden, A .......................................................... 59Bolos, M ........................................................ 116Bond, C ......................................................... 106Boone, C......................................................... 60Bovellan, M ..................................................... 59Bowles, J ...................................................... 120Boyd, SE ......................................................... 15Bradshaw, RA ................................................ 117Braet, F ........................................................... 13Brooks, DA ................................................... 121Brygula, ME. .................................................... 40Bugarcic, A ...................................................... 33Bunnett, NW .................................................... 98Burchfield, JG ............................... 19, 20, 28, 2Burgess, AG .................................................... 17Burgess, AW .................................................... 72Butler, L ......................................................... 121Bcking, T ....................................................... 49Canals, M ....................................................... 98Cao, B ..................................................... 31, 119Cao, M ............................................................. 70Cao, Y ............................................................. 40Casanova, JC .................................................. 48Cesare, AJ ....................................................... 43Charras, G ....................................................... 59Chaudhuri, R ............................................ 22, 68Cheng, TS ....................................................... 11Chen, Y ........................................................... 10Chia, PC ........................................................ 103Chircop, M ......................................................... 5Chtanova, T .................................................... 94Churches, QI ................................................... 31

Cockburn, IA .................................................. 90Coin, L ............................................................ 70Collett, M ....................................................... 115Colquhoun, D .................................................. 88Conduit, S ..................................................... 105Conway, JRW .................................................. 45Cooper, HM ...................................... 37, 38, 114Cooper, ST ..................................................... 32Costa, MW....................................................... 15Coster, A .......................................................... 49Coulson, EJ ................................................... 36Cox, H ..................................................... 38, 114Croucher, DR ................................................. 58Daly, RJ .......................................................... 62Darby, W .......................................................... 47Davis, M .......................................................... 51Demont, Y ..................................................... 117Dodding, MP ................................................ 102Dodson, E................................................. 25, 74Dodt, H............................................................ 96Domanova, W........................................... 19, 68Dowd, GC ................................................... 8, 12Dowling, MR. ................................................... 21du Roure, O ....................................................111Dyson, J ........................................................ 105D'Souza, RC ...................................................... 9Elsworth, B............................................... 24, 29Erami, Z ........................................................... 45Faulkner, S .................................................... 117Faux, MC ........................................................ 72Fazakerley, DJ ................................................... 2Fernandez-Rojo, MA ...................................... 17Fey, D .............................................................. 58Filipovska, A .................................................. 82Fiveash, C ....................................................... 83Foa, L ............................................................ 116Foc, K ............................................................ 114Fok, K .............................................................. 38Fok, K ............................................................. 37Follett, J.......................................................... 33Foster, LE ........................................................ 27Fox, AH ......................................................... 106Furtado, MB .................................................... 15Fu, N ............................................................. 110Gabrielli, B ....................................................... 26Gale, A .............................................................. 1Gallego-Ortega, D ........................................... 45Gall, M ............................................................ 10Ganesamoorthy, D .......................................... 70Garbis, SD ....................................................... 27Gardiner, BS .................................................. 57Gartner, A ........................................................ 52Gaus, K ....................................................... 4, 95Genheden, M .................................................. 27George, AJ ..................................................... 75Gianfelice, A .................................................... 12Glanfield, A ...................................................... 17Gleeson, PA ................................................. 103Gokoolparsadh, A ............................................ 53Gomez, G ...................................................... 109Gong, X ........................................................... 78


Gorrell, M................................................... 10, 16Gorse, A .......................................................... 64Gould, CM ....................................................... 75Gould, K .......................................................... 24Grassinger, J ................................................. 119Gratton, E ........................................................ 95Grau, G ........................................................... 92Greenland, EL ................................................. 39Greer, PA ......................................................... 32Gressin, L .......................................................111Grodzinsky, AJ ................................................. 57Grounds, MD ............................................ 41, 87Gruenberg, J ................................................ 112Guerin, C ........................................................111Guillotin, A ......................................................111Gunning, PW ............................................... 6, 49Hahn, MA ........................................................ 44Halasz, M ........................................................ 58Halls, ML ......................................................... 98Hamilton, N ................................................... 109Hamson, E ...................................................... 10Handoko, Y ................................................ 24, 29Hannan, RD .................................................... 75Hardeman, EC .................................................. 6Hart-Smith, G ................................................. 54Harvey, AR ...................................................... 41Hatwell-Humble, J ........................................... 30Haylock, DN .................................................... 30Hayward, NK ................................................... 26Heath, WR ....................................................... 93Heazlewood, CK ....................................... 30, 31Heazlewood, SY ............................................. 30Heinzel, S ........................................................ 21Hennig, S ...................................................... 106Hermann, D ................................................... 118Hernandez-Varas, P ........................................ 78Herrmann, D ................................................... 45Heuvingh, J ....................................................111Hickey, M ......................................................... 92Hickey, MJ ...................................................... 91Hill, A .............................................................. 77Hinde, E .......................................................... 95Hirose, T ........................................................ 106Hoang-Le, D .................................................... 17Hodgetts, SI .................................................... 41Hodgkin, PD. ................................................... 21Hondermarck, H .......................................... 117Hong, W .......................................................... 12Hor, J ............................................................... 93Hughes, JN .................................................... 46Hughes, W ...................................................... 28Hughes, WE ...................................................... 2Humbert, PO ..................................................... 7Hunt, N ............................................................ 92Hussain, M ...................................................... 35Huynh, M ......................................................... 13Ibanez, C ...................................................... 113Iconomou, M ................................................... 18Ireton, K ...................................................... 8, 12Jain, R ............................................................ 92

James, DE .......... 2, 9, 19, 20, 22, 23, 28, 50, 68James, SA ....................................................... 31Jans, DA ....................................................... 107Jobling, P ....................................................... 117Johnson, IRD ................................................ 121Johnson, M ........................................................ 1Johnston, APR ............................................. 101Johnston, HE ................................................... 27Kable, E ........................................................... 13Kan, A ............................................................. 21Kar, S .............................................................. 57Kaslin, J ......................................................... 88Keane, F .................................................... 10, 16Kean, B ............................................................. 8Kee, AJ ............................................................. 6Kenney, JW ..................................................... 27Kerr, MC ....................................................... 100Kholodenko, BN .............................................. 58Kile, B ................................................................ 6King, LE ........................................................... 72Kiss, A ............................................................. 78Kitano, H................................................... 15, 80Kolch, W .......................................................... 58Koopman, P ................................................... 120Kowalewski, J .................................................. 78Kroschwald, S ................................................. 59Krycer, JR ...................................... 19, 20, 28, 68Kumar, S ......................................................... 97Kuncic, Z ................................ 19, 20, 23, 56, 68Kuyucak, S ...................................................... 23Lamond, A ....................................................... 52Larance, M ..................................................... 52Lazarou, M...................................................... 84Lee, N ....................................................... 37, 38Lee, NK ......................................................... 114Lek, A .............................................................. 32Lemckert, FA ................................................... 32Le, PH.B. ......................................................... 12Lindeman, GJ ................................................ 110Lindsey, B ........................................................ 88Liu, H ............................................................. 101Locasale, J ..................................................... 76Lock, JG ......................................................... 78Madhamshettiwar, P ........................................ 75Madhavan, V ................................................... 35Magenau, A ..................................................... 45Mahalingam, S ............................................... 69Makinen, VV-P ................................................ 55Mamaghani, M ................................................ 78Manent, J .......................................................... 7Mann, G .......................................................... 67Manousopoulou, A ........................................... 27Mansfield, JH .................................................. 48Maqsudi, S ...................................................... 16Marchingo, JM. ................................................ 21Markham, JF. ................................................... 21Marks, N .......................................................... 36Ma, M ................................................................ 5Ma, X ............................................................... 22McAninch, D .................................................... 46

McCaughan, G ................................................ 16McDermott, M .................................................... 1McDivitt, T ....................................................... 12McGhee, E .............................................. 45, 118McGlinn, E ...................................................... 48McIntyre, P ...................................................... 47McKenna, J ..................................................... 18McMenamin, P ................................................ 92McQualter, RJ ................................................. 30Mellick, GD ...................................................... 64Messerschmidt, D ....................................... 104Michelot, A ....................................................111Miller, ES ........................................................ 35Mitchell, A .................................................. 47, 92Mitchell, CA .................................................. 105Modi, P ............................................................ 35Montgomery, M ................................................ 83Mueller, SN ..................................................... 93Munn, AL ........................................................ 44Murrow, BA ........................................................ 9Murtaza, M ...................................................... 64Myers, G ......................................................... 66Nambiar, V ...................................................... 41Ng, P ............................................................... 11Nicovich, PR. ............................................... 4, 49Nikolic, I ............................................. 24, 25, 74Nikolic, I ........................................................... 29Nilsson, SK ...................................... 30, 31, 119Nim, HT ........................................................... 15Nobis, M ................................................. 45, 118Norris, D ................................................... 19, 28North, KN ........................................................ 32Nourse, C ...................................................... 114Nunnari, J ....................................................... 81Obeidy, P ........................................................ 49Oliveira, SMR ................................................ 117Oorschot, V ....................................................... 3Oteiza, A .......................................................... 30O'Leary, C ..................................................... 114O'Leary, JJ .................................................... 121Padman, B ........................................................ 3Pai, S ............................................................... 92Paluch, EK ...................................................... 59Pandzic, E ............................................. 4, 49, 95Papaioannou, A ............................................. 23Papayannopoulou, T ..................................... 119Papa, A ........................................................... 34Parker, BL ........................................................ 22Parkinson-Lawrence, EJ ............................... 121Parton, RG. .................................................... 89Pavlos, NJ ................................................ 11, 99Pavlyshyn, D ................................................... 21Pearson, RB .................................................... 75Penninger, JM ................................................... 7Pernigo, S ............................................... 40, 102Pickett, HA ....................................................... 43Piltz, S ............................................................. 46Piper, A ............................................................ 32Pixley, FJ ........................................................ 39Planade, J ......................................................111

Pleines, I ........................................................... 6Polishchuk, E .................................................... 6Polishchuk, R .................................................... 6Polly, P ............................................................ 83Pourkarimi, E ................................................... 52Pourqui, O .................................................... 85Powell, J ......................................................... 63Priya, R ......................................................... 109Prosser, HM .................................................... 48Proud, CG....................................................... 27Pundavela, J ................................................. 117Qian, L ............................................................. 36Quinn, A ......................................................... 120Quinn, RJ ........................................................ 64Ramm, GA .................................................. 3, 17Reddel, RR. ..................................................... 40Redpath, GMI .................................................. 32Reischmann, N ................................................ 45Reitsma, A ....................................................... 30Richardson, HE ................................................. 7Rigano, LA. ..................................................... 12Rios, AC ....................................................... 110Rizos, H ........................................................... 26Roberts-Thompson, M .................................. 116Robinson, P ................................................. 115Rodriguez, N ..................................................... 5Romeo, Y ........................................................ 59Roselli, S ....................................................... 117Rosenthal, NA .......................................... 15, 86Rossy, J ............................................................ 4Rother, N ........................................................... 4Roux, PP ......................................................... 59Russell, S ..................................................... 108Saila, S ............................................................ 12Sanger, A ....................................................... 102Sansom, O .................................................... 118Saunders, D ................................................... 18Schaefer, E ...................................................... 18Schwartz, MG .................................................. 48Sedger, L ........................................................... 1Sengupta, S .................................................... 35Shafqat, H ....................................................... 78Shamra, A ........................................................ 36Shavlakadze, T ................................................ 41Shearer, R ....................................................... 18Simpson, K .................................... 24, 25, 29, 74Simpson, KJ .......................................... 7, 72, 75Skalamera, D .................................................. 26Small, DH ...................................................... 116Smith, DW ....................................................... 57Sobey, T .......................................................... 49Sobey, T .......................................................... 49Sobinoff, AP. ............................................ 40, 43Southam, K ................................................... 116Stagg, SM. ..................................................... 12Steiner, RA .................................................... 102Step

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