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> pars cutanea (covered by skin) > anterior palpebral surface > derivatives of skin: hair follicles, sebaceous gll., eccrine sweat gll. > layers of striated muscles > orbicularis oculi m. (& levator palpebrae superior m.) > tarsus / tarsal plate > dense fibro-elastic plate > tarsales gll. / Meibomian gll. > elongated holocrine gll. (modified sebaceous gll.) > compound gland, which opens freely (separate from hair follicles) > tarsal muscles are anchored onto the plate > smooth muscle (!!!), innervated by sympathetic nerves > pars conjunctivalis (covered by conjunctiva) > facies posterior palpebrae > conjunctival epithelium > towards the limbus palpebralis posterior > non-keratinized stratified squamous epithelium > close to the fornix conjunctivae > stratified columnar epithelium > goblet cells in the surface layer > conjunctival mucous secretion > accessory lacrimal glands (gll. lacrimales accessoriae) > e.g. glands of Krause > in the vicinity of the superior conjunctival fornix

Histology of the Eyelid

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Page 1: Histology of the Eyelid

> pars cutanea (covered by skin)> anterior palpebral surface

> derivatives of skin: hair follicles, sebaceous gll., eccrine sweat gll.> layers of striated muscles

> orbicularis oculi m. (& levator palpebrae superior m.)> tarsus / tarsal plate

> dense fibro-elastic plate> tarsales gll. / Meibomian gll.

> elongated holocrine gll. (modified sebaceous gll.)> compound gland, which opens freely (separate from hair follicles)

> tarsal muscles are anchored onto the plate> smooth muscle (!!!), innervated by sympathetic nerves

> pars conjunctivalis (covered by conjunctiva)> facies posterior palpebrae

> conjunctival epithelium> towards the limbus palpebralis posterior

> non-keratinized stratified squamous epithelium> close to the fornix conjunctivae

> stratified columnar epithelium> goblet cells in the surface layer

> conjunctival mucous secretion> accessory lacrimal glands (gll. lacrimales accessoriae)

> e.g. glands of Krause> in the vicinity of the superior conjunctival fornix

Page 2: Histology of the Eyelid

pars conjunctivalis

orbicularis oculi m.

tarsal plate

Meibomian glandexcretory duct

conjunctival epithelium

pars cutanea (skin)

gland of Zeisseyelash

Page 3: Histology of the Eyelid

pars cutanea

hair follicle

orbicularis oculi m.

tarsal plate

Meibomian gland (secretory acinus)

Page 4: Histology of the Eyelid

> limbus palpebralis anterior (anterior edge of the free margin of the eyelid)

> (in its vicinity)

> eyelashes (cilia)

> is devoid of arrector pili m.

> glands that open into the pilosebaceus duct of eyelashes

> glands of Zeiss

> ordinary sebaceous glands

> ciliary glands of Moll

> apocrine sweat gll.

> wide lumen

> simple colied tubules

> limbus palpebralis posterior (posterior edge of the free margin of the eyelid)

> (in its vicinity)

> tarsal glands of Meibom

> 12-30 glands in each eyelid

Page 5: Histology of the Eyelid

pars cutanea (cutaneous surface)

orbicularis oculi m.

hair follcicle

eccrine sweat gland

limbus palpebralis anterior

gland of Zeiss

eyelash

Page 6: Histology of the Eyelid

tubulo-alveolar gland> serous secretory portions (acini)

> lumens are wide> secration of tears

> watery fluid containing lysozyme> electrolites of similar concentration to the plasma> moistens and lubricates the eyeball and eyelids

> myoepithelial cells around> excretory duct

> dozen or more small ducts into the superior fornix> tears drain into the nasal cavity via the nasolacrimal duct

comparison of the lacrimal gland with other serous glandsthe lacrimal gland lacks the following items:

> intercalated tubules> striated ducts> centroaciner cells> islets of Langerhans

Page 7: Histology of the Eyelid

secretory portions excretory duct

plasma cell

lymphocytes