Upload
others
View
8
Download
2
Embed Size (px)
Citation preview
Healing & Repair
Dr Sameh Abou-Beih Lecturer of Pathology
Fayoum University
Types of Cells
• Labile
• Stable
• Permanent
• Stem cells
Factors affecting repair
• General – Age – Debilitating conditions – Ptn deficiency – Vitamin & trace element deficiency – Drugs
• Local – Severity – Cell type – Bl supply – Infection & FB
Growth factors
Healing by fibrosis
• Angiogenesis
• Fibrogenesis
• Maturation of scar
• Remodelling of fibrous tissue
Examples of healing
Complication of Wound Healing
• Ulcer
• Fistula
• Sinus
• Implantation
• Keloid
• Contractures
• Carcinoma
Causes of Malunion
• Local
– Infection
– Poor opposition
– Mobilization
– Poor bl supply
• General
– Old age
– Malnutrition
Thank You