Efficacy of tart cherry juice in reducing muscle

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    Efficacy of tart cherry juice in reducing

    muscle pain during running :a randomized controlled trial

    MARNIAR

    C209118041

    Kuehl et al.

    Journal of the International Society of Sports Nutrition 2010, 7:17

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    INTRODUCTION

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    Long distance

    runningacute muscle damage

    acute inflammation

    decreased forceproduction

    can last up to

    1 week

    post-exercise

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    One proposed mechanism :

    extensive myofibril disruption triggers a

    local inflammatory response

    MUSCLE DAMAGE

    NSAIDsadverseeffects >>

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    Tart cherries :

    a good source of phenolic

    compounds withhighlevels of

    antioxidant and antiinflammatory

    activity

    cherry consumption before and

    during strenuous exercise mayhave a protectiveeffect to reduce

    muscle damage andpain

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    Some studies :

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    Consumption of approximately 45 cherries per

    day has been shown to reduce circulating

    concentrations of inflammatory markers in

    health

    y men and wom

    en (Connolly DA et.al., 2006 ;Jacob RA et.al., 2003)

    it is possible that the anti-inflammatory and/or

    the antioxidant effects of cherry juice may

    mediate this secondary response and avoid theproliferation of myofibrillar disruption

    (Connolly DA et.al., 2003)

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    METHODS

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    EXCLUSION

    CRITERIA :

    recent use of other

    pain management

    methods

    ARANDOMIZED, PLACEBO-CONTROLLED,DOUBLE- BLINDTRIAL

    ICLUSIONCRITERIA :

    an ability and

    willingness to abstain

    from anti-inflammatory

    or pain-relieving drugs

    willingness to refrain

    from seeking any othertreatment for symptoms

    of muscle damageuntil

    the completion of the

    study

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    RESULT

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    runners in both groups reported more pain

    upon completion of the race

    participants who drank the tart cherry juice

    twice daily for one week prior to and the

    day of the race reported a significantlysmaller increase in pain after the race

    In this study

    tart cherry juice provideda protective benefit against

    the acute muscle pain

    caused by distance running

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    pain associated with acute muscle injury is most

    likely due to oxidative tissue damage whichleads

    to an inflammatory response, causing furtherproduction of free radicals and augmenting

    secondary muscle soreness

    nutritional antioxidants have been proposed as a

    means of mitigating muscle soreness and strength

    loss caused by damaging exercise

    tart cherries contain flavinoids and

    anthocyanins, withhigh antioxidant

    and anti-inflammatory properties

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    Limitations of this study

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    the subjective of assessment of pain by

    participants

    the possibility of cross contamination of the

    intervention and placebo drinks, as participantsmay have potentially switched drinks to compare

    flavor and effects

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    CONCLUSIONS

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    tart cherries havehighlevels of antioxidant and

    anti-inflammatory compounds, and are promoted in

    lay publications as beneficial for those witharthritis, muscle pain, and fibromyalgia

    the present study suggests that the administration

    of tart cherry juice foreight days reducedsymptoms ofexercise-induced muscle pain among

    runners participating in a vigorous endurance

    event

    further research is needed to examine serum

    biomarkers and the potentialexplanation for the

    reduction in pain and inflammation associated with

    tart che

    rry consu

    mption

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    terima kasih

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    VAS pain scale

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    VAS pain scale