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    Evidence-Based Nursing

    PracticePaolo D. Vega, RN

    Critical Care Services Manager

    Chong Hua HospitalJanuary 22, 2014

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    Objectives

    Describe evidence-based practice (EBP)

    Identify levels of evidence using the EBPpyramid

    Learn where to find the best evidence

    Understand why evidence-based practice isimportant and should be integrated in scholarly

    work Learn the importance of EBP, QI and NR in the

    Nursing Practice.

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    What is Evidence-Based Nursing

    Practice?

    "Evidence-based nursing (EBN) means using the bestavailable evidence from research, along with patientpreferences and clinical experience, when makingnursing decisions.

    (Cullum N. Users' guides to the nursing literature: an introduction. Evid Based Nurs 2000Jul;3(3):71-2. doi:10.1136/ebn.3.3.71)

    Integrated components:

    clinical expertise (best practice) external evidence from systematic research

    patient preferences(Sackett, et al., 1996)

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    The EBM Triad

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    Process of Evidence-Based

    Nursing Practice

    Assess and define problem.

    Formulate specific question.

    Locate and evaluate appropriate evidence.

    Integrate evidence into planning and

    implementing interventions.

    Evaluate process and results.

    (Sackett, et al., 1996)

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    Process of Evidence-Based Nursing

    Practice is also the Nursing Process

    Evidence-based Nursing

    Assess and define problem.

    Formulate specific question. Locate and evaluate

    appropriate evidence.

    Integrate evidence intoplanning and implementing

    interventions. Evaluate process and results.

    Nursing Process

    Assessment

    Diagnosis Planning

    Intervention

    Evaluation

    We just have to emphasize the EVIDENCE!!!

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    Is Evidence-Based

    Nursing Practice the same

    as Nursing Research?

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    What makes good evidence?

    Good

    Based on scientific

    research Randomized Control

    Trials

    Systematic review

    Meta-analysis

    Clinical guidelines

    Shoddy

    Opinion

    Consensus

    Because its been donethis way for 100 years

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    Chocolate decadence

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    Searching for Evidence Pyramid: Basic

    Systematic

    Reviews,

    Meta-

    Analyses

    Evidence Summaries,

    Evidence Guidelines

    Randomized Controlled Trials (RCTs),

    Cohort Studies, Qualitative Studies

    Background Information, Expert Opinion

    ex. Cochrane

    ex. DynaMed, Nursing

    Reference Center, NGC

    ex.

    MEDLINE/PubMed,

    CINAHL

    ex.Textbooks,

    UptoDate

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    Pyramid of Evidence

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    Where do you look for

    evidence?

    Wikipedia?

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    Search for the Best Evidence to

    answer the Question MEDLINE or PubMed www.pubmed.gov

    CINAHL/CINAHL Plus Cumulative Index to Nursing andAllied Health Literature www.cinahl.com

    E-Journals

    Clinical Practice Guidelines National GuidelineClearinghouse www.guideline.gov

    Nursing Reference Centerwww.ebscohost.com/pointOfCare/evidence-based-information

    Advanced Google or Google Scholar

    http://www.pubmed.gov/http://www.cinahl.com/http://www.guideline.gov/http://www.ebscohost.com/pointOfCare/evidence-based-informationhttp://www.ebscohost.com/pointOfCare/evidence-based-informationhttp://www.ebscohost.com/pointOfCare/evidence-based-informationhttp://www.ebscohost.com/pointOfCare/evidence-based-informationhttp://www.ebscohost.com/pointOfCare/evidence-based-informationhttp://www.ebscohost.com/pointOfCare/evidence-based-informationhttp://www.guideline.gov/http://www.cinahl.com/http://www.pubmed.gov/
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    CINAHL vs MEDLINE

    CINAHL

    Coverage: 1982+

    Indexes 1700 journals

    Focuses on nursing andallied health literature

    CINAHL Thesaurus withmore nursing terms

    Has peer-reviewed limit

    Includes cited referencesat end of many refs

    MEDLINE

    Coverage: late 1940s+

    Indexes 5000 journals

    Focuses on biomedicalliterature

    Uses MeSH as itscontrolled vocabulary

    No peer-reviewed limit

    No cited references

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    Why Evidence Based Practice?

    Knowledge explosion+

    Nursing shortage

    Timely research evidence translation intobest practice.

    (Melnyk & Fineout-Overholt, 2005; Salmon, 2007)

    Mandate

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    Why Evidence Based Practice?

    Traditional practice Knowledge gained in school

    Pathophysiological rationale

    Intuition

    Experiences (past & usual practice)

    Workplace colleagues

    (Melnyk & Fineout-Overholt, 2005; Salmon, 2007)

    17-year lag between research findings andpractice application

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    Why Evidence Based Practice?

    Results in better patient outcomes Failure to use evidence results in lower

    quality, less effective, more expensive

    care(Berwick DM, 2003)

    EBP can lead to:

    Increased practitioner satisfaction Decreased burnout and turnover

    Third party reimbursement

    (Melnyk & Fineout-Overholt, 2005; Salmon, 2007)

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    Why do nurses need to do EBP?

    Keeps practice current and relevant

    Increases confidence in decision making

    Experience greater autonomy in practice Increases level of job satisfaction

    Berwick DM. Disseminating innovations in health care. JAMA 2003 Apr16;289(15):1969-75

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    Barriers to Nurses using EBP

    Lack of TIME

    Lack of value of research in practice

    Lack of understanding of electronicdatabases to find evidence

    Lack of computer skills

    Lack of EBP mentors at point of care Difficulty understanding research articles

    Pravikoff DS, Tanner AB, Pierce ST. Readiness of U.S. nurses for

    evidence-based practice. Amer J Nurs 2005 Sep;105(9): 40-52.

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    Why Evidence Based Practice?

    Evidence continually evolves

    Evidence-based practice

    Opinion-based

    Melnyk & Fineout-Overholt, 2005; Salmon, 2007

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    WARNING!!!!!

    EBP does not replace clinical reasoning orjudgment.

    20% medical practice

    Primary Research

    (Salmon, 2007)

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    What is Evidence Based Practice?

    Conscientious use of best evidence inclinical decision making:

    Systematic search for best evidence

    Critical appraisal of most relevant evidence toanswer clinical question

    Clinical context or circumstances

    Ones own clinical experience Patient preferences and values

    (Melnyk & Fineout-Overholt, 2005; Salmond,2007)

    EBP is more than research utilization

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    History of EBP Movement

    Dr. Archie Cochrane, British epidemiologist In 1972 criticized medical profession for lack

    of systematic review of available evidence to

    direct clinical decision making Landmark caseseveral RCTs supporting

    effectiveness of corticosteroid therapy to haltpremature labor in high risk women had not beensystematically analyzed 1,000s of low-birth-weight premature infants continued

    to die needlessly

    Review data showed therapy decreased death from 30%to 50%

    Melnyk & Fineout-Overholt, 2005

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    History of EBP Movement

    2000 IOM report, To Err is Human

    Preventable medical errors were 8thleadingcause of death in US

    2002 IOM report, Crossing the QualityChasm

    Major lag between medical science andtechnology advancements and healthcaredelivery

    (Salmon, 2007)

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    5 (7) Steps for EBN Practice

    1. Convert your information into an answerablequestion (PICO) Population; Intervention; Comparison; Outcome

    2. Search the literature for the best available evidence

    3. Critically appraise the evidence for validity andusefulness

    4. Apply the findings to your clinical practice alongwith clinical expertise and patients perspective to plan

    care5. Evaluate the outcomes of your practice decisions orchanges based on evidence.

    Melnyk & Fineout-Overholt, 2005

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    2 Additional Steps for EBP=7 Steps

    Step 0: Cultivate a spirit of inquiry

    Step 6: Disseminate EBP results

    Melnyk BM, Fineout-Overholt E, Stillwell SB, Williamson KM. Evidence-basedpractice: step by step: the seven steps of evidence-based practice. Am J Nurs2010 Jan;110(1):51-3. PMID: 20032669.

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    Levels and Grades of Evidence

    REPROLINE, Johns Hopkins University www.reproline.jhu.edu

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    Additional Point of Care Evidence-

    Based Resources for Nursing:[have some level of evidence-based information]

    Clini-eguide Nursing Advisorwww.clineguide.com/nursing-standards-care-plan.aspx

    Lippincotts Nursing Procedures & Skillswww.healthstream.com/Lippincott/

    Mosbys Nursing Consultwww.nursingconsult.com

    Mosbys Nursing Skills mosbysnursingskills.com

    UptoDate www.uptodate.com

    http://www.clineguide.com/nursing-standards-care-plan.aspxhttp://www.clineguide.com/nursing-standards-care-plan.aspxhttp://www.healthstream.com/Lippincott/http://www.nursingconsult.com/http://www.uptodate.com/http://www.uptodate.com/http://www.nursingconsult.com/http://www.healthstream.com/Lippincott/http://www.clineguide.com/nursing-standards-care-plan.aspxhttp://www.clineguide.com/nursing-standards-care-plan.aspxhttp://www.clineguide.com/nursing-standards-care-plan.aspxhttp://www.clineguide.com/nursing-standards-care-plan.aspxhttp://www.clineguide.com/nursing-standards-care-plan.aspxhttp://www.clineguide.com/nursing-standards-care-plan.aspxhttp://www.clineguide.com/nursing-standards-care-plan.aspx
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    Cochrane Database of

    Systematic ReviewsGold standard for high quality systematic

    reviews

    Includes full-text reviews and protocols

    Cochrane Abstracts available in CINAHLand MEDLINE/PubMed

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    So, you want to use Google?

    Not a problem!!! Google www.google.com

    Largest search engine: over 25 billionpages

    Relevance ranking based on link analysis

    Google Advanced Search

    www.google.com/advanced_search?hl=en Google Scholar

    www.scholar.google.com

    http://www.google.com/http://www.google.com/advanced_search?hl=enhttp://www.scholar.google.com/http://www.scholar.google.com/http://www.google.com/advanced_search?hl=enhttp://www.google.com/
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    But use Google Scholar!!!

    www.scholar.google.com Searches for scholarly literature, including peer-

    reviewed papers, theses, books, abstracts andtechnical reports

    Finds articles from academic publishers, professionalsocieties, universities, etc. as well as scholarlyarticles on the web

    "Cited by" link identifies # that have cited the

    original Access to full text only available with subscription

    Caution: Not a reliable sole source for searchingscholarly literature

    http://www.scholar.google.com/http://www.scholar.google.com/
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    Criteria for Evaluating Web Siteswww.healthlinks.washington.edu/howto/navigating/criteria.pdf

    Authority

    Accuracy

    Objectivity

    Currency

    Coverage

    Design

    http://www.healthlinks.washington.edu/howto/navigating/criteria.pdfhttp://www.healthlinks.washington.edu/howto/navigating/criteria.pdf
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    Questions???

    Lets hear from

    Prof. Sharon Hewner, PhD, RNAsst. Professor of Nursing

    State University of New York at Buffalo

    School of Nursing

    on her discussion on HOW

    EVIDENCE-BASED PRACTICE, QUALITY and NURSINGRESEARCH form the bench-stool of Nursing practice.

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    Hungry for more???

    We invite you to the 1stEvidence-basedResearch Workshop here in Cebu..

    WHEN: April 25-26, 2014 (2-day Workshop)

    WHERE: Chong Hua Hospital, AB Conf. Room

    SPEAKER: Ms. Lee Banguilan, RN, MAN

    Head, Nursing Research Dept.Philippine Heart Center, QC

    PRICE: Php 1,200 (inclusive of kit, ID and lunch)

    FREE for Chong Hua Hospital employees

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    Thank you!!!!

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    1. Ask the burning question using

    PICO

    P: Patient, population, or problem beingaddressed

    I: Intervention or dimension of interest

    C: Comparison intervention O: Outcome

    Format helps focus the question bydetermining the important concepts

    Not necessary to follow above order

    (Melnyk & Fineout-Overholt, 2005; Salmon, 2007)

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    PICO Examples

    Intervention focused clinical question: In teenagers (patient population), how effective is

    Depo-Provera (intervention) in the prevention ofpregnancy (outcome)?

    Non-intervention focused question: What is the duration of breast feeding (outcome) in

    new mothers (population) who have breast-related-

    complications (area of interest) in the first 3 monthsafter the infants birth versus those who do not havebreast related complications (comparison)?

    (Salmon, 2007)

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    2. Collect most relevant and

    best evidence1. Systematic review/meta-analysis of all RCTs or

    evidence-based clinical practice guidelines2. At least one well-designed RCT3. Well-designed controlled trials without

    randomization4. Well designed case-control and cohort studies5. Systematic review of descriptive and qualitative

    studies6. Single descriptive or qualitative study7. Opinion of authorities and/or reports of expert

    committees

    (Melnyk & Fineout-Overholt; 2005)

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    2. Collect most relevant and

    best evidence

    Evidence Based Clinical Practice Guideline

    Based on scientific literature

    Explicitly documents process used to develop

    statement

    Grades strength of evidence used

    (www.chestnet.org/education/guidelines/currentGuidelines.php; cited in Melnyk

    & Fineout-Overholt, 2005)

    http://www.chestnet.org/education/guidelines/currentGuidelines.phphttp://www.chestnet.org/education/guidelines/currentGuidelines.php
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    2. Collect most relevant and

    best evidence

    Systematic Review:

    Rigorous systematic review of primary studies

    Preplanned comprehensive search strategy

    Relevant articles

    appraised

    data synthesized

    results interpreted summary of best available evidence provided

    (Salmon, 2007)

    Precise; minimizes error & bias

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    2. Collect most relevant and

    best evidence

    Meta-analysis:

    Integrates results of similar descriptive orqualatitative studies

    Meta-synthesis:

    Statistical method

    Integrates results of several independent studies

    addressing a set or related research hypotheses Objective appraisal

    Precise estimate of treatment effect

    (Salmon, 2007)

    C

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    2. Collect most relevant and

    best evidence

    RCT: Gold Standard for intervention studies

    Most reliable

    Treatment randomization eliminates large amount ofbias

    Cohort Study:

    Observational longitudinal study with 2 patient groups One group receives treatment

    Groups measured over time for development ofoutcomes

    (Salmon, 2007)

    2 C ll l d

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    2. Collect most relevant and

    best evidence

    Case-control studies:

    Compares patients who have a specificcondition to people who do not

    Uses medical records and/or patient recall

    Less reliable than RCTs and cohort studies

    showing a statistical relationship does notnecessarily mean clinical causal relationship

    (Salmon, 2007)

    2 C ll t t l t d

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    2. Collect most relevant and

    best evidence

    Qualitative Research: Collects data through observations and interviews

    Generates ideas and hypotheses through inductive

    Descriptive Studies:

    Can be quantitative or qualitative

    Describe what is going on

    Expert Opinion

    (Salmon, 2007)

    S h St t

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    Search Strategy

    1. Determine appropriate data base for question

    2. Determine type of study design that would bestanswer question

    3. Enter a subject heading (e.g., MeSH in PubMed)and/or textword search guided by the PICOcomponents of the question

    4. Combine searches to find relevant evidence

    5. Further restrict combined searches for study design,methods, indicators of clinical meaningfulness, English,human

    6. Apply pre-established inclusion & exclusion criteria tostudies gathered by the search

    (Salmon, 2007)

    Pre-appraised literature is golden

    3 C iti ll A i E id

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    3. Critically Appraise Evidence

    RCT

    Rapid Screening

    Random allocation of interventions?

    Blindness to interventions by

    Researchers?

    Participants?

    Involved health care professionals?

    (Melnyk & Fineout-Overholt; 2005)

    3 C iti ll A i E id

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    3. Critically Appraise Evidence

    Systematic Review

    Rapid Appraisal

    Relevant papers identified?

    Method of assessing quality of papers?

    Method of summarizing results?

    (Melnyk & Fineout-Overholt; 2005)

    3 C iti ll A i E id

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    3. Critically Appraise Evidence

    Qualitative Research

    Lincoln & Gubas Evaluative Criteria:

    Trustworthiness

    Credibility (internal validity)

    Transferability (external validity) Dependability (reliability)

    Confirmability (objectivity)

    (Melnyk & Fineout-Overholt; 2005)

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    4.Integrate Evidence/Patient

    Preferences/Values/Clinical Experience

    Evidence assists but does not replacesound clinical reasoning.

    EvidenceAnalogy

    Experience

    Meaning Theory

    Salmon, 2007)

    4 I t t E id /P ti t

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    4.Integrate Evidence/Patient

    Preferences/Values/Clinical Experience

    Is evidence useful for this particularpatient?

    Cost effective? Patient values and preferences?

    Clinician expertise?

    Best clinical decision makingis

    integrative and collaborative!

    Salmon, 2007)

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    5. Implement & Evaluate Impact

    Track outcomes

    Include patients evaluations

    Requires informatics for imputing & tracking

    Patient

    Treatment

    Outcome