Curriculum Vitae

Mr. James Kinross BSc (Hons ), MB BS, PhD , FRCS ( Gen)

Curriculum Vitae Mr. James Kinross BSc (Hons), MBBS, FRCS (Gen), PhD

Address

Date of Birth

38 Kempe road,Queens Park,London NW6 1SJ07989 3442380207 286 5635j.kinross@imperial.ac.uk

19/05/1976

Nationality

GMC no.

CCT date

MDDUS no.

Qualifications

Awards / Prizes

British

6029260

01/10/2014

M212755

FRCS (Gen) (2012) Royal college of surgeons of England

PhD (2011) Imperial College London

MRCS (2005) The Royal College of Surgeons of England

MB BS (2001) Imperial College London

BSc (Hons) (1998) Class 2.1 Pharmacology and Toxicology The University of London

DDW 2018 Poster of Distinction: James Alexander. ASMS Poster Award 2018 – Petra Paizs AACR 2018 Scholar-in-Training Awards ($2K) : Liam R.

Poynter. Modulation of cellular phospholipids correlates with tumor regression grade and radio resistance in rectal cancer.

AACR 2018 Poster of Distinction: Liam Poynter. St. Gallen 2018: Best poster (€2K) Liam Poynter. Gerald Marks Rectal Cancer Prize – SAGES 2016. Ethicon laparoscopic colorectal training award (2013): Training

fellowship involved advanced laparoscopic training in Colchester and ESI, Hamburg.

Association for surgical education (2013): Orlando, USA. Paper of distinction.

International Surgical Week (2011): Yokohama, Japan Highest

Professional bodies and learned societies

Visiting Professorship

Fellowships / Grants

impact paper IASMEN Imperial College NHS trust travelling fellowship award 2011 and

2012. £2000 The Department of Biosurgery and Surgical Technology Research

Meeting (2009) Best poster award: Metabonomic profiling of secondary peritonitis

Imperial College Business Ideas Challenge (December 2007) £1,000 for the creation of a novel patient choice website.

The Department of Biosurgery and Surgical Technology Research Meeting (December 2007) Best Poster Award: Metabonomic profiling of intestinal ischaemia / reperfusion in the rat.

Medical Futures Innovation Award (June 2007) Winner of the ‘Critical Care / Anaesthetics’ category for the design of a novel crash trolley.

Imperial College Innovations Award (July 2006) £14,000 for the development of chest drain surgical appliance.

ACPGBI AACR

I am a visiting Professor at the Royal College of Surgeons of Ireland, where I collaborate with Prof. Jochen Prehn, the director of the systems medicine unit at the RCSI on the bioenergetics of Colon Cancer.

2020 Defence and Security Accelerator Grant (PI) – Hololens for

clinical education - £50K Johnson and Johnson Education award (PI) - PanSurg (£106K)

2018 Horizon 2020 (Co-I) GROWTH – Horizon 2020 network training

grant. € 2.2 million RAC grant (PI) – £100K. Big data analysis of real time road

traffic accidents. BRC (£20K) REIMS FIT (PI) testing augmentation:

Development of novel biomarkers for screening of colorectal cancer based on lipidomic analysis of faecal samples.

NIHR i4i (PI) I Endoscope (PI) £1.2 million

2017 CRUK centre clinical research fellowship (PI) £256,000 CRUK meeting award for 1st International Cancer

Microbiome Consortium Meeting (PI) - £15K Multimodal Mapping for Robotic Surgery (Co-I): Fusing Rapid

Evaporative Ionisation Mass Spectrometry (REIMS) with 3D Ultrasound Imaging in a Robust Tracking Framework. Society of American Gastrointestinal and Endoscopic Surgeons. £40,789.

Metabolic biomarkers for Early Colon cancer and advanced AdeNOma Study (MECANO) PI.  – Commercial study with

UDX. £182,161. Biomedical Research Centre for Gut health, Imperial. Co-I

£346,546 NIHR Translational Patient Safety Research Centre: Co-I.

£7,959,250

2016 NIH - Diet, the microbiota and its metabolites in colon cancer risk

in Alaska Native People (Co-I). £39,571.2015

Bowel Cancer Research: PI £50,000, 24 months. Metagenome-metabonome linked analysis of dysplasia in adenomatous polyps and early colorectal cancer.

2014 Ethicon Laparoscopic Colorectal Fellowship - £40,000. Colchester

University Foundation Trust / ICENI centre. (October 2014 – April 2015)

Imperial BRC – CO-I £40,000 Rapid evaporative ionization mass spectrometry (REIMS) for the analysis of cancer resection margins in locally advanced and recurrent rectal cancer.

Imperial BRC – PI Prof. Tekkis. Imperial / Marsden BRC – CO-I £280,000. Metabonome-microbiome

mapping of colorectal cancer. PI: Prof. Teare2013

Imperial BRC – CO-I £14,600 Multi-Disciplinary Simulator and Virtual Patients for Trauma and Surgery-related Scenario Training

Imperial BRC (PI)– Co-I £22,00 Pilot study of continuous metabolic profile monitoring and immediate neurological injury detection during thoracic aortic repair: P48265. PI Prof. Cheshire.

Academy of medical sciences: PI £42,476 Clinical lecturer starter grant. Chemically augmented imaging of gut microbiome / host interactions.

Imperial BRC: CO-I £127,909 Molecular phenotyping of neuroendocrine tumours – a novel approach in personalised patient journey. PI Prof. Andrea Frilling.

Imperial BRC: CO-I £100,000 PRofiling of Anal Carcinoma to improve outcomes - PrACar study (PI: Mr. Paul Ziprin).

2012

EU FP7-Health innovation: CO-I £2,547,291 Intelligent surgical device PI: Zoltan Takats.

2008-2011 Biomedical Research Centre (BRC) grant: CO-I £380,794

September 2011. A new Molecular Imaging Approach to Augment Histopathological diagnosis in diseases of the colon PI Prof. The Lord Ara Darzi of Denham 31675

Institut Merieux: CO-I £300,808 May 2011. Elucidation of Gut-

Education

Microbial Metabolic Linkage to Blood Pressure and Obesity. PI Prof. Jeremy Nicholson P36760

Biomedical Research Centre (BRC) grant: CO-I £257,045 May 2011. Stratification of intensive care patients: prediction of sepsis risk and improved therapeutic management. (PI Elaine Holmes P33324)

Biomedical Research Centre (BRC) grant: CO-I £434,559 September 2010. Coupling Diathermy to Mass Spectrometry to Develop Real-Time Surgical Diagnostics and New Decision Capabilities (PI Prof. The Lord Ara Darzi of Denham P33320)

Wellcome Trust translational award: CO-I £189,511 July 2008. The development of a smart crash trolley (PI Prof. Charles Vincent)

Training Hub For Operative Technologies In Healthcare (THOTH) CO-I £75,000 January 2008. Creation of a virtual training tool for the use of medical devices in the NHS. PI Prof. Ara Darzi of Denham.

The Royal College of Surgeons of England PI £42,000. August 2007. 1 Year Research Fellowship

I have supported the following grants as a collaborator:

CRUK: CO-I £1,793,5502012. Roles of NF-B in the control of inflammation and BR metabolism in colon cancer. Application Reference: C26587/A15115PI Prof. Guido Franzoso

Science Foundation Ireland: Investigator Programme Grant 2013. €2,266,294. BCL02 family proteins and cellular bioenergetics in the control of cell survival.: Towards novel predictive and prognostic markers of disease progression and therapy response in colorectal cancer patients. PI Prof Jochen Prehn, Royal College of Surgeons of Ireland.

Imperial College School of Medicine at St. Mary’s Hospital, London.1995-2001

Charterhouse School, Godalming, Surrey.1989–1994

Current Employment

Clinical career

Senior Lecturer and consultant in Colorectal Surgery:October 2015 until presentDivision of Surgery, Department of Surgery and cancer, Faculty of Medicine, Imperial College London.

I am an academic colorectal surgeon. My clinical focus is:

1. Laparoscopic surgery for the colon and rectum and colorectal

Commercial and industrial positions

Patents

cancer. This includes Trans Anal Minimally Invasive surgery for early rectal cancer and organ preservation in early rectal cancer.

2. Robotic surgery for rectal cancer: I am involved in the trial and assessment of novel robotic surgical platforms (Transenterix systems).

3. Surgical nutrition for improved peri-operative outcomes.

2020/ Director – Caerulean health. Commercial gut health testing2020/ Director 1 World Medical – Global PPE innovation company2019/20 LNC therapeutics advisory board2017/19 Verb Surgical Robotics Advisory board2018/19 Safeheal Advisory board2017/19 Consultant for Ethicon (Johnson and Johnson)2016- Director Renegade Medical – industrial design company. I am

the chief medical officer. Raised VC funding to develop a commercial smart infusion device. EU and US patent pending.

2010- Director Getwell Media - Raised 75K from Innovate UK for the development of health based games and AI driven peer review.

In Vivo Endoscopic Tissue Identification ToolInventors: Julia Balog, Tamas Karancsi, Steven Derek Pringle, Zoltan Takats, James Kinross, Jeremy K NicholsonPublication date: 2018/2/22Patent office US Application number 15555888

Publications H index: 39Citations: 10227Total peer reviewed full papers: 92Total peer reviewed published abstracts: 28Total conference abstracts: 37Total book chapters: 7

Refereed full papers 1. Zhou J, Otter JA, Price JR, Cimpeanu C, Garcia DM, Kinross J, et al.

Investigating SARS-CoV-2 surface and air contamination in an acute healthcare setting during the peak of the COVID-19 pandemic in London. Clin Infect Dis. 2020.

2. Herzig DO, Ogilvie JW, Chudzinski A, et al. Assessment of a circular powered stapler for creation of anastomosis in left-sided colorectal surgery: A prospective cohort study. Int J Surg. 2020;84:140-146.

3. Lam K, Clarke J, Purkayastha S, Kinross JM. Uptake and accessibility of surgical robotics in England. Int J Med Robot. 2020:e2174.

4. Mason SE, Scott AJ, Markar SR, et al. Insights from a global snapshot of the change in elective colorectal practice due to the COVID-19 pandemic. PLoS One. 2020;15(10):e0240397.

5. Diederen K, Li JV, Donachie GE, et al. Exclusive enteral nutrition mediates gut microbial and metabolic changes that are associated with remission in children with Crohn's disease. Sci Rep. 2020;10(1):18879.

6. Clarke J, Murray A, Markar SR, Barahona M, Kinross J, PanSurg C. New geographic model of care to manage the post-COVID-19 elective surgery aftershock in England: a retrospective observational study. BMJ Open. 2020;10(10):e042392.

7. Denning M, Goh ET, Scott A, et al. What Has Been the Impact of Covid-19 on Safety Culture? A Case Study from a Large Metropolitan Healthcare Trust. Int J Environ Res Public Health. 2020;17(19).

8. Zakka K, Erridge S, Chidambaram S, Kynoch M, Kinross J, Purkayastha S, on behalf of the PanSurg collaborative group. Electrocautery, Diathermy, and Surgical Energy Devices: Are Surgical Teams at Risk During the COVID-19 Pandemic? Annals of Surgery, 2020.

9. Markar SR, Clarke J, Kinross J, PanSurg Collaborative g. Practice patterns of diagnostic upper gastrointestinal endoscopy during the initial COVID-19 outbreak in England. Lancet Gastroenterol Hepatol. 2020;5(9):804-5.

10. Bhangu A, Collaborative RSGobotWMR. Evaluation of appendicitis risk prediction models in adults with suspected appendicitis. Br J Surg. 2020;107(1):73-86.

11. Collaborative CO. Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study. Lancet. 2020;396(10243):27-38.

12. Collaborative CO. Global guidance for surgical care during the COVID-19 pandemic. Br J Surg. 2020;107(9):1097-1103.

13. Tan BYQ, Kanneganti A, Lim LJH, et al. Burnout and Associated Factors Among Health Care Workers in Singapore During the COVID-19 Pandemic. J Am Med Dir Assoc. 2020;21(12):1751-1758 e1755.

14. Martin G, Koizia L, Kooner A, Cafferkey J, Ross C, Purkayastha S, et al. Use of the HoloLens2 Mixed Reality Headset for Protecting Health Care Workers During the COVID-19 Pandemic: Prospective, Observational Evaluation. J Med Internet Res. 2020;22(8):e21486.

15. Zakka K, Chidambaram S, Mansour S, Mahawar K, Salminen P, Almino R, et al. SARS-CoV-2 and Obesity:“CoVesity”-A Pandemic Within A Pandemic. Gastrointestinal Surgery 2020.

16. Chidambaram S, Erridge S, Kinross J, Purkayastha S, on behalf of the PanSurg Collaborative3. An observational study on mobile health applications for COVID-19 in the United Kingdom. Lancet Digital Health 2020

17. Qiu S, Nikolaou S, Zhu J, Jeffery P, Goldin R, Kinross J, et al. Characterisation of the Expression of Neurotensin and Its Receptors in Human Colorectal Cancer and Its Clinical Implications. Biomolecules. 2020;10(8).

18. Mason S, Manoli E, Poynter L, Alexander J, Paizs P, Adebesin A, et al. Mass spectrometry transanal minimally invasive surgery (MS-TAMIS) to promote organ preservation in rectal cancer. Surg Endosc. 2020;34(8):3618-25.

19. Galaiya R, Kinross J, Arulampalam T. Factors associated with burnout syndrome in surgeons: a systematic review. Ann R Coll Surg Engl. 2020:1-8.

20. Markar SR, Martin G, Penna M, Yalamanchili S, Beatty JW, Clarke J, Erridge S, Sounderajah V, Denning M, Scott A et al: Changing the Paradigm of Surgical Research During a Pandemic. Ann Surg 2020.

21. Kinross JM, Mason SE, Mylonas G, Darzi A: Next-generation robotics in gastrointestinal surgery. Nat Rev Gastroenterol Hepatol 2020.

22. Tankel J, Yellinek S, Vainberg E, David Y, Greenman D, Kinross J, Reissman P: Sarcopenia defined by muscle quality rather than quantity predicts complications following laparoscopic right hemicolectomy. Int J Colorectal Dis 2020, 35(1):85-94.

23. Ocvirk S, Wilson AS, Posma JM, Li JV, Koller KR, Day GM, Flanagan CA, Otto JE, Sacco PE, Sacco FD et al: A prospective cohort analysis of gut microbial co-metabolism in Alaska Native and rural African people at high and low risk of colorectal cancer. Am J Clin Nutr 2020, 111(2):406-419.

24. Galaiya R, Kinross J, Arulampalam T: Factors associated with burnout syndrome in surgeons: a systematic review. Ann R Coll Surg Engl 2020:1-8.

25. Duff SE, Battersby CLF, Davies RJ, Hancock L, Pipe J, Buczacki S, Kinross J, Acheson AG, Walsh CJ: The use of oral antibiotics and mechanical bowel preparation in elective colorectal resection for the reduction of surgical site infection. Colorectal Dis 2020, 22(4):364-372.

26. Collaborative CO, Nepogodiev D, Glasbey JC, Li E, Omar OM, Simoes JF, et al. Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study. Lancet (London, England). 2020.

27. Collaborative CO, Bhangu A, Lawani I, Ng-Kamstra JS, Wang Y, Chan A, et al. Global guidance for surgical care during the COVID-19 pandemic. The British journal of surgery. 2020.

28. Aggarwal R, Winter Beatty J, Kinross J, von Roon A, Darzi A, Purkayastha S: Initial Experience With a New Robotic Surgical System for Cholecystectomy. Surg Innov 2020, 27(2):136-142.

29. Hall A, Leff, D , Wojdecka, A, Kinross J, Thompson P, Darzi. Beyond the healthcare paradigm: Co-creating a new model for collaborative transdisciplinary healthcare design education. Design Society, 2019. https://doi.org/10.35199/epde2019.16

30. Scott AJ, Alexander JL, Merrifield CA, et al. International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis. Gut 2019; 68(9): 1624-32.

31. Poynter L, Galea D, Veselkov K, et al. Network Mapping of Molecular Biomarkers Influencing Radiation Response in Rectal Cancer. Clin Colorectal Cancer 2019; 18(2): e210-e22.

32. Mason SE, Poynter L, Takats Z, Darzi A, Kinross JM. Optical Technologies for Endoscopic Real-Time Histologic Assessment of

Colorectal Polyps: A Meta-Analysis. Am J Gastroenterol 2019; 114(8): 1219-30.

33. Lewis J, Kinross J. Mechanical bowel preparation for elective colorectal surgery. Tech Coloproctol 2019; 23(8): 783-5.

34. Cameron SJS, Alexanders J, Bolt F, et al. Evaluation of Direct from Sample Metabolomics of Human Faeces using Rapid Evaporative Ionisation Mass Spectrometry (REIMS). Anal Chem 2019.

35. Martin G, Ghafur S, Kinross J, Hankin C, Darzi A. WannaCry-a year on. BMJ. 2018;361:k2381

36. Jitsumura M, Cunningham AL, Hitchings MD, Islam S, Davies AP, Row PE, Riddell AD, Kinross J, Wilkinson TS, Jenkins GJ, Williams JG, Harris DA. Protocol for faecal microbiota transplantation in ulcerative colitis (FMTUC): a randomised feasibility study. BMJ Open. 2018 Oct 18;8(10):e021987

37. Kinross JM. Precision gaming for health: Computer games as digital medicine. Methods. 2018 Sep 29. pii: S1046-2023(17)30366-3

38. Pouncey AL, Scott AJ, Alexander JL, Marchesi J, Kinross J. Gut microbiota, chemotherapy and the host: the influence of the gut microbiota on cancer treatment. Ecancermedicalscience. 2018 Sep 5;12:868.

39. Alexander JL, Scott AJ, Pouncey AL, Marchesi J, Kinross J, Teare J. Gut microbiota, chemotherapy and the host: the influence of the gut microbiota on cancer treatment. Ecancermedicalscience. 2018 Sep 5;12:865

40.Clift AK, Kornasiewicz O, Drymousis P, Faiz O, Wasan HS, Kinross JM, et al. Goblet cell carcinomas of the appendix: rare but aggressive neoplasms with challenging management. Endocr Connect. 2018;7(2):268-77.

41.Jitsumura M, Kokelaar RF, Kinross J, Hitchings M, Row P, Davies A, et al. Faecal Microbiota Transplant in Ulcerative Colitis (Fmtuc) - a Phase II Single-Blind Randomised Clinical Trial. Brit J Surg. 2018;105:20-.

42.Pawa N, Clift AK, Osmani H, Drymousis P, Cichocki A, Flora R, et al. Surgical Management of Patients with Neuroendocrine Neoplasms of the Appendix: Appendectomy or More. Neuroendocrinology. 2018;106(3):242-51.

43.Galea D, Inglese P, Cammack L, Strittmatter N, Rebec M, Mirnezami R, et al. Translational utility of a hierarchical classification strategy in biomolecular data analytics. Sci Rep. 2017;7(1):14981.

44.Kinross J, Mirnezami R, Alexander J, Brown R, Scott A, Galea D, et al. A prospective analysis of mucosal microbiome-metabonome interactions in colorectal cancer using a combined MAS 1HNMR and metataxonomic strategy. Sci Rep. 2017;7(1):8979.

45.Scott AJ, Merrifield CA, Alexander JL, Marchesi JR, Kinross JM. Highlights from the Inaugural International Cancer Microbiome Consortium Meeting (ICMC), 5-6 September 2017, London, UK. Ecancermedicalscience. 2017;11:791.

46.Wolfer AM, Scott AJ, Rueb C, Gaudin M, Darzi A, Nicholson JK, Holmes E, Kinross JM: Longitudinal analysis of serum oxylipin profile as a novel descriptor of the inflammatory response to surgery. J Transl Med 2017, 15(1):83.

47.Mason SE, Kinross JM, Hendricks J, Arulampalam TH: Postoperative hypothermia and surgical site infection following peritoneal insufflation with warm, humidified carbon dioxide during laparoscopic colorectal surgery: a cohort study with cost-effectiveness analysis.

Surgical endoscopy 2017, 31(4):1923-192948.Martin G, Kinross J, Hankin C: Effective cybersecurity is fundamental

to patient safety. Bmj 2017, 357:j2375.49.Kinross J: Race-specific differences in mucosal sulfidogenic bacteria

modify colon cancer risk. Gut 2017.50.Inglese P, McKenzie JS, Mroz A, Kinross J, Veselkov K, Holmes E,

Takats Z, Nicholson JK, Glen RC: Deep learning and 3D-DESI imaging reveal the hidden metabolic heterogeneity of cancer. Chem Sci 2017, 8(5):3500-3511.

51.Alexander JL, Wilson ID, Teare J, Marchesi JR, Nicholson JK, Kinross JM: Gut microbiota modulation of chemotherapy efficacy and toxicity. Nature reviews Gastroenterology & hepatology 2017.

52.Alexander J, Gildea L, Balog J, Speller A, McKenzie J, Muirhead L, Scott A, Kontovounisios C, Rasheed S, Teare J, Takats Z, Kinross, J: A novel methodology for in vivo endoscopic phenotyping of colorectal cancer based on real-time analysis of the mucosal lipidome: a prospective observational study of the iKnife. Surgical endoscopy 2017, 31(3):1361-1370.

53.Marchesi JR, Adams DH, Fava F, Hermes GD, Hirschfield GM, Hold G, Quraishi MN, Kinross J, Smidt H, Tuohy KM et al: The gut microbiota and host health: a new clinical frontier. Gut 2016, 65(2):330-339.

54.Balog, J.; Kumar, S.; Alexander, J.; Golf, O.; Huang, J.; Wiggins, T.; Abbassi-Ghadi, N.; Enyedi, A.; Kacska, S.; Kinross, J. Hanna, G.B., Nicholson, J.K, Takats, Z. In Vivo Endoscopic Tissue Identification by Rapid Evaporative Ionization Mass Spectrometry (REIMS). Angew Chem Int Ed Engl 2015, 54, (38), 11059-62.

55.Penney, N. C.; Kinross, J. M.; Newton, R. C.; Purkayastha, S., The role of bile acids in reducing the metabolic complications of obesity after bariatric surgery: A systematic review. Int J Obes (Lond) 2015.

56.Tekkis, P.; Tan, E.; Kontovounisios, C.; Kinross, J.; Georgiou, C.; Rasheed, S.; Brown, G., Hand-sewn coloanal anastomosis for low rectal cancer; technique and long term outcome. Colorectal Dis 2015.

57.O’Keefe SJD, Li JV, Lahti L, Ou J, Carbonero F, Mohammed K, Posma JM, Kinross J, Wahl E, Ruder E et al: Fat, fibre and cancer risk in African Americans and rural Africans. Nat Commun 2015, 6, 6342 May 2015.

58.Scott AJ, Mason SE, Arunakirinathan M, Reissis Y, Kinross JM, Smith JJ: Risk stratification by the Appendicitis Inflammatory Response score to guide decision-making in patients with suspected appendicitis. The British journal of surgery 2015, 102(5):563-572.

59.Kontovounisios C, Kinross J, Tan E, Brown G, Rasheed S, Tekkis P: Complete mesocolic excision in colorectal cancer: a systematic review. Colorectal disease, 2015, 17(1):7-16.

60.Golf O, Strittmatter N, Karancsi T, Pringle SD, Speller AV, Mroz A, Kinross JM, Abbassi-Ghadi N, Jones EA, Takats Z: Rapid evaporative ionization mass spectrometry imaging platform for direct mapping from bulk tissue and bacterial growth media. Analytical chemistry 2015, 87(5):2527-2534

61.Villasenor A, Kinross JM, Li JV, Penney N, Barton RH, Nicholson JK, Darzi A, Barbas C, Holmes E: 1H NMR global metabolic phenotyping of acute pancreatitis in the emergency unit. Journal of proteome research 2014, 13(12):5362-5375.

62.Veselkov KA, Mirnezami R, Strittmatter N, Goldin RD, Kinross J, Speller AV, Abramov T, Jones EA, Darzi A, Holmes E et al: Chemo-

informatic strategy for imaging mass spectrometry-based hyperspectral profiling of lipid signatures in colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America 2014, 111(3):1216-1221.

63.Mirnezami R, Spagou K, Vorkas PA, Lewis MR, Kinross J, Want E, Shion H, Goldin RD, Darzi A, Takats Z et al: Chemical mapping of the colorectal cancer microenvironment via MALDI imaging mass spectrometry (MALDI-MSI) reveals novel cancer-associated field effects. Molecular oncology 2014, 8(1):39-49.

64.Mirnezami R, Jimenez B, Li JV, Kinross JM, Veselkov K, Goldin RD, Holmes E, Nicholson JK, Darzi A: Rapid diagnosis and staging of colorectal cancer via high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy of intact tissue biopsies. Annals of surgery 2014, 259(6):1138-1149.

65.Kontovounisios C, Baloyiannis Y, Kinross J, Tan E, Rasheed S, Tekkis P: Modified right colon inversion technique as a salvage procedure for colorectal or coloanal anastomosis. Colorectal disease, 2014, 16(12):971-975.

66.Kinross J, Li JV, Muirhead LJ, Nicholson J: Nutritional modulation of the metabonome: applications of metabolic phenotyping in translational nutritional research. Current opinion in gastroenterology 2014, 30(2):196-207.

67.Dumas ME, Kinross J, Nicholson JK: Metabolic phenotyping and systems biology approaches to understanding metabolic syndrome and fatty liver disease. Gastroenterology 2014, 146(1):46-62.

68.Cesario A, Auffray C, Agusti A, Apolone G, Balling R, Barbanti P, Bellia A, Boccia S, Bousquet J, Cardaci V et al: A systems medicine clinical platform for understanding and managing non- communicable diseases. Current pharmaceutical design 2014, 20(38):5945-5956.

69.Lee H, Beales S, Kinross J, Burns E, Darzi A: The extent of rationing of surgical procedures in England. Lancet 2013, 381(9866):534-535.

70.Kinross JM, Markar S, Karthikesalingam A, Chow A, Penney N, Silk D, Darzi A: A meta-analysis of probiotic and synbiotic use in elective surgery: does nutrition modulation of the gut microbiome improve clinical outcome? JPEN Journal of parenteral and enteral nutrition 2013, 37(2):243-253.

71.Kinross JM, Drymousis P, Jimenez B, Frilling A: Metabonomic profiling: a novel approach in neuroendocrine neoplasias. Surgery 2013, 154(6):1185-1192; discussion 1192-1183.

72. Jimenez B, Mirnezami R, Kinross J, Cloarec O, Keun HC, Holmes E, Goldin RD, Ziprin P, Darzi A, Nicholson JK: 1H HR-MAS NMR spectroscopy of tumor-induced local metabolic "field-effects" enables colorectal cancer staging and prognostication. Journal of proteome research 2013, 12(2):959-968.

73.Balog J, Sasi-Szabo L, Kinross J, Lewis MR, Muirhead LJ, Veselkov K, Mirnezami R, Dezso B, Damjanovich L, Darzi A et al: Intraoperative tissue identification using rapid evaporative ionization mass spectrometry. Science translational medicine 2013, 5(194):194ra193.

74.Takats Z, Denes J, Kinross J: Identifying the margin: a new method to distinguish between cancerous and noncancerous tissue during surgery. Future oncology 2012, 8(2):113-116.

75.Patel V, Lee H, Taylor D, Aggarwal R, Kinross J, Darzi A: Virtual worlds are an innovative tool for medical device training in a simulated environment. Studies in health technology and informatics 2012, 173:338-343.

76.Nicholson JK, Holmes E, Kinross JM, Darzi AW, Takats Z, Lindon JC: Metabolic phenotyping in clinical and surgical environments. Nature 2012, 491(7424):384-392.

77.Nicholson JK, Holmes E, Kinross J, Burcelin R, Gibson G, Jia W, Pettersson S: Host-gut microbiota metabolic interactions. Science 2012, 336(6086):1262-1267.

78.Mirnezami R, Kinross JM, Vorkas PA, Goldin R, Holmes E, Nicholson J, Darzi A: Implementation of molecular phenotyping approaches in the personalized surgical patient journey. Annals of surgery 2012, 255(5):881-889.

79.Markar SR, Karthikesalingam A, Thrumurthy S, Muirhead L, Kinross J, Paraskeva P: Single-incision laparoscopic surgery (SILS) vs. conventional multiport cholecystectomy: systematic review and meta-analysis. Surgical endoscopy 2012, 26(5):1205-1213.

80.Markar SR, Blackburn S, Cobb R, Karthikesalingam A, Evans J, Kinross J, Faiz O: Laparoscopic versus open appendectomy for complicated and uncomplicated appendicitis in children. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2012, 16(10):1993-2004.

81.Markar S, Kinross J: Authors' reply to: single-incision laparoscopic surgery (SILS) vs. conventional multiport cholecystectomy: systematic review and meta-analysis. Surgical Endoscopy and Other Interventional Techniques 2012, 26(10):3000-3001.

82.Kinross J, Nicholson JK: Gut microbiota: Dietary and social modulation of gut microbiota in the elderly. Nature reviews Gastroenterology & hepatology 2012, 9(10):563-564.

83.Holmes E, Kinross J, Gibson GR, Burcelin R, Jia W, Pettersson S, Nicholson JK: Therapeutic modulation of microbiota-host metabolic interactions. Science translational medicine 2012, 4(137):137rv136.

84.Markar SR, Venkat-Raman V, Ho A, Karthikesalingam A, Kinross J, Evans J, Bloom I: Laparoscopic versus open appendicectomy in obese patients. International journal of surgery 2011, 9(6):451-455.

85.Markar SR, Karthikesalingam AP, Venkat-Ramen V, Kinross J, Ziprin P: Robotic vs. laparoscopic Roux-en-Y gastric bypass in morbidly obese patients: systematic review and pooled analysis. The international journal of medical robotics + computer assisted surgery : MRCAS 2011, 7(4):393-400.

86.Li JV, Ashrafian H, Bueter M, Kinross J, Sands C, le Roux CW, Bloom SR, Darzi A, Athanasiou T, Marchesi JR et al: Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk. Gut 2011, 60(9):1214-1223.

87.Kinross JM, Holmes E, Darzi AW, Nicholson JK: Metabolic phenotyping for monitoring surgical patients. Lancet 2011, 377(9780):1817-1819.

88.Kinross JM, Darzi AW, Nicholson JK: Gut microbiome-host interactions in health and disease. Genome medicine 2011, 3(3):14.

89.Kinross JM, Alkhamesi N, Barton RH, Silk DB, Yap IK, Darzi AW, Holmes E, Nicholson JK: Global metabolic phenotyping in an experimental laparotomy model of surgical trauma. Journal of proteome research 2011, 10(1):277-287.

90.Patel V, Aggarwal R, Kinross J, Taylor D, Davies R, Darzi A: Improving informed consent of surgical patients using a multimedia-based program?: results of a prospective randomized multicenter study of patients before cholecystectomy. Annals of surgery 2009, 249(3):546-547; author reply 547-548.

Refereed Published Abstracts

91.Kinross J, Warren O, Basson S, Holmes E, Silk D, Darzi A, Nicholson JK: Intestinal ischemia/reperfusion injury: defining the role of the gut microbiome. Biomarkers in medicine 2009, 3(2):175-192.

92.Kinross J, von Roon AC, Penney N, Holmes E, Silk D, Nicholson JK, Darzi A: The gut microbiota as a target for improved surgical outcome and improved patient care. Current pharmaceutical design 2009, 15(13):1537-1545.

93.Leong JJ, Kinross J, Taylor D, Purkayastha S: Surgeons have held conferences in Second Life. Bmj 2008, 337:a683.

94.Kinross JM, von Roon AC, Holmes E, Darzi A, Nicholson JK: The human gut microbiome: implications for future health care. Current gastroenterology reports 2008, 10(4):396-403.

95.Warren O, Alexiou C, Massey R, Leff D, Purkayastha S, Kinross J, Darzi A, Athanasiou T: The effects of various leukocyte filtration strategies in cardiac surgery. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2007, 31(4):665-676.

96.Rekhraj S, Kinross J, Prabhudesai S, Darzi A, Ziprin P: Intraperitoneal chemotherapy as first-line treatment in the management of epithelial ovarian cancer. Mini reviews in medicinal chemistry 2007, 7(5):509-517.

97.Mangoush O, Purkayastha S, Haj-Yahia S, Kinross J, Hayward M, Bartolozzi F, Darzi A, Athanasiou T: Heparin-bonded circuits versus nonheparin-bonded circuits: an evaluation of their effect on clinical outcomes. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2007, 31(6):1058-1069.

98.Kinross J, Warren O, Silk D, Darzi A: Perioperative synbiotic treatment to prevent postoperative infectious complications in biliary cancer surgery: a randomized control trial. Annals of surgery 2007, 245(6):1000.

99.Warren O, Kinross J, Paraskeva P, Darzi A: Emergency laparoscopy--current best practice. World journal of emergency surgery : WJES 2006, 1:24.

100. Purkayastha S, Chow A, Athanasiou T, Cambaroudis A, Panesar S, Kinross J, Tekkis P, Darzi A: Does serum procalcitonin have a role in evaluating the severity of acute pancreatitis? A question revisited. World journal of surgery 2006, 30(9):1713-1721.

101. Kinross J, Warren O, Darzi A: ATLS versus ETC: time for a decision? Annals of emergency medicine 2006, 48(6):761-762.

102. Aziz O, Athanasiou T, Panesar SS, Massey-Patel R, Warren O, Kinross J, Purkayastha S, Casula R, Glenville B, Darzi A: Does minimally invasive vein harvesting technique affect the quality of the conduit for coronary revascularization? The Annals of thoracic surgery 2005, 80(6):2407-2414.

103. Kinross, J. James A. W. P. DeLany Kathryn, R.Koller, Flora Sapp Gretchen Day, Peter Holck, Alison Morris, Timothy Thomas, Stephen J.O'Keefe, Jeremy K.Nicholson, Grace F. Barker. Sa1860 - Metabolic Phenotyping of African and Alaskan Indigenous Populations Demonstrates that Urbanization Modifies Gut Microbiome Metabolic Functions Associated with Colon Cancer Risk. Gastroenterology, Vol. 154, issue 6, Spp. 1. May 2018. Pages S-422. https://doi.org/10.1016/S0016-5085(18)31683-4

104. Alexander JL, Scott A, Poynter LR, McDonald JA, Cameron S, Inglese P, Doria L, Kral J, Hughes DJ, Susova S, Liska V, Soucek P, Hoyles L, Gomez-Romero M, Nicholson JK, Takats Z, Marchesi J, Kinross JM, Teare JP. The Colorectal Cancer Mucosal Microbiome is Defined by Disease Stage and the Tumour Metabonome. Gastroenterology. 2018;154(6):S-415.

105. Alexander JL, Scott A, Poynter LR, McDonald JA, von Roon AC, Marchesi J, Kinross JM, Teare JP. Tu1876 - The Effect of Bowel Purgative Medication on the Mucosa-Associated Microbiota may be less Significant than we Thought. Gastroenterology. 2018;154(6, Supplement 1):S-1044-S-5.

106. Sonia Mansukhani, Michael Davidson, Angela Gillbanks, Clare Peckitt, Annette Musallam, Ruwaida Begum, Daniel Morganstein, Andrew Wotherspoon, Angela M Riddell, James M Kinross, Julian Marchesi, Katharina von Loga, William H Allum, Sheela Rao, David J Watkins, Ian Chau, David Cunningham, Naureen Starling, Asif Chaudry, Marco Gerlinger. Iconic: Peri-operative immuno-chemotherapy in operable oesophageal and gastric cancer. Journal of Clinical Oncology 2018, 36 (15) TPS4139-TPS4139

107. Scott A, Lewis M, Gomez-Romero M, Cloarec O, Ziprin P, Kennedy R, et al. Longitudinal Analysis of Urinary Metabolic Phenotype after Colorectal Resection Demonstrate Temporal Evolution. Dis Colon Rectum. 2017;60(6):E121-E.

108. *Alexander J, Perdones-Montero A, Scott A, Poynter L, Atkinson S, Soucek P, et al. A Prospective Multi-National Study of the Colorectal Cancer Mucosal Microbiome Reveals Specific Taxonomic Changes Indicative of Disease Stage and Prognosis. Gut. 2017;66:A32-A3.

109. Alexander J, Poynter L, Scott A, Perdones-Montero A, Hughes D, Susova S, et al. A Prospective Multi-Centered Analysis of the Rectal Cancer Mucosal Microbiome during Neoadjuvant Long Course Chemoradiotherapy. Dis Colon Rectum. 2017;60(6):E118-E.

110. Alexander JL, Perdones-Montero A, Cameron S, Scott A, Poynter LR, Inglese P, Atkinson SR, Soucek P, Hughes D, Susova S et al: A Prospective Multi-National Study of the Colorectal Cancer Mucosal Microbiome Reveals Specific Taxonomic Changes Indicative of Disease Stage and Prognosis. Gastroenterology 2017, 152(5):S1010-S1011.

111. Diederen K, Li J, Kindermann A, Benninga MA, De Meij T, De Groot EF, et al. Exclusive Enteral Nutrition Mediates Gut Metabolic Changes in Children with Crohn's Disease. Gastroenterology. 2017;152(5):S617-S.

112. Alexander J, Mroz A, Perdones-Monteiro A, Scott A, Gildea L, Cameron S, Bolt F, Rosini R, R. G, Mckenzie J et al: Targeted Chemical Analysis of the Colon Cancer Microbiome Using Desorption Electrospray Ionisation Mass Spectrometry Imaging (DESI). United European Gastroenterology Journal, UEGW; Vienna; 2016: A67.

113. Kinross J, Muirhead L, Alexander J, Balog J, Guallar-Hoya C, Speller A, Golff O, Goldin R, Darzi A, Nicholson J et al: iKnife: Rapid evaporative ionization mass spectrometry (REIMS) enables real-time chemical analysis of the mucosal lipidome for diagnostic and prognostic use in colorectal cancer. Cancer Research. AACR: New Orleans; 2016: 3977.

114. Alexander JL, Scott A, Mroz A, Perdones-Montero A, McKenzie J, Rees DN, Speller A, Veselkov K, Kinross JM, Takats Z et al: 91 Mass

Published abstracts, international presentations and posters

Spectrometry Imaging (MSI) of Microbiome-Metabolome Interactions in Colorectal Cancer. Gastroenterology 2016, 150(4):S23.

115. Purkayastha S, Penney NC, Kinross JM, Newton RC: The Role of Bile Acids Following Metabolic Surgery. Obesity Surgery 2014, 24(8):1293-1294.

116. Muirhead LJ, Kinross J, Balog J, Guallar-Hoyas C, Speller AV, Goldin RD, Nicholson JK, Takats Z, Darzi AW: Near Real Time Characterisation of Colorectal Cancer and Adenomatous Polyps Using Rapid Evaporative Ionisation Mass Spectrometry (Reims). Gastrointestinal Endoscopy 2014, 79(5):AB554

117. Kontovounisios C, Baloyiannis Y, Kinross J, Tan E, Rasheed S, Tekkis P: Modified right colon inversion technique as a salvage procedure for low colorectal or coloanal anastomosis-long term outcomes. In: Tripartite meeting 2014. vol. 16: Colorectal Disease; 2014 41-68.

118. Kinross J, Muirhead LJ, Mirnezami R, Veselkov K, Jiminez B, Marchesi J, Nicholson JK, Darzi AW: Microbiome-Metabonome Linked Analysis of Ascending Colon Cancer by 1HNMR MAS Spectrometry and 16S rRNA Gene Analysis (Metataxonomics). Gastroenterology 2014, Volume 146(Issue 5):Supplement 1, Page S-688.

119. Jimenez B, Drymousis P, Kinross J, Nicholson J, Frilling A: Metabonomic Profiling: A Novel Approach in Neuroendocrine Neoplasias. In: 11th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease: 2014; 2014: 227-227

120. Muirhead L, Balog J, Kinross J, Guallar-Hoyas C, Veselkov K, Sasi-Szabo L, Dezso B, Damjanovich L, Nicholson JK, Takats Z et al: The intelligent knife: near real time characterisation of colorectal cancer using rapid evaporative ionisation mass spectrometry (REIMS). In: 8th Annual Meeting of the European Society of Coloproctology. vol. 15. Belgrade: Colorectal Disease; 2013: (Suppl. 3), 13–26

121. Kinross J, Mirnezami R, Muirhead L, Takats Z, Nicholson J, Marchesi J, Darzi A: 16S rRNA gene analysis (metataxonomics) of the ascending colonic cancer microbiological ecosystem. In: 8th Annual Meeting of the European Society of Coloproctology: 2013; Begrade: Colorectal Disease; 2013: 15 (Suppl. 13), 13–26.

122. Patel V, Lee H, Taylor D, Aggarwal R, Kinross J, Darzi A: Virtual worlds are an innovative tool for medical device training in a simulated environment. In: Medicine Meets Virtual Reality 19: 2013; Los Angeles: IOS Press; 2013.

123. Mirnezami R, Veselkov K, Strittmatter N, Kinross JM, Goldin RD, Speller A, Jones EA, Holmes E, Abramov T, Nicholson JK et al: Novel data processing and image co-registration algorithm for region-specific lipid profiling in colorectal cancer tissue using DESI imaging mass spectrometry. In: Journal of Clinical Oncology: 2013; 2013: e14620.

124. Li J, Kinross J, Ou JH, Carbonero F, Vipperla K, Ruder EH, Newton K, Naidoo VG, DeLany JP, Zoetendal EG et al: A High Fat Lower Fiber Dietary Intervention Perturbs the Urinary Metabonome and Gut Microbial Co-Metabolic Processes in a Population of African and African Americans. Gastroenterology 2013, 144(5):S348-S348.

125. Lee H, Beales S, Kinross J, Burns E, Darzi A: The extent of rationing of surgical procedures by primary care trusts in england. Brit J Surg 2013, 100:37-37.

126. Hicks L, Walker DG, Eng D, Jiminez B, Kinross J, Holmes E,

Williams HR, Orchard TR: Urinary Metabolic Profiling of Inflammatory Bowel Disease in a South Asian Cohort. Gastroenterology 2013, 144(5):S653-S653.

127. Antcliffe DB, Veselkov K, Pearce JTM, Kinross J, Gordon AC: Trajectory Analysis of Clinical Variables to Improve Diagnosis of Ventilator Associated Pneumonia in Patients Wan Brain Injury. Intens Care Med 2013, 39:S312-S313.

128. Darzi A, Muirhead LJ, Sasi-Szabó L, Balog J, Mirnezami R, Kinross J, Lewis MR, Veselkov K, Damjanovich L, Nicholson JK et al: The iKnife: Analysis of diathermy plumes by high-resolution mass spectrometry provides real-time identification of colorectal cancer liver metastases Qatar Foundation Annual Research Forum Proceedings; 2012.

129. Kinross J, Vernazza J, Holloway P, Holmes E, Darzi A: Metabonomic profiling of plasma in secondary peritonitis: A novel diagnostic and prognostic strategy based on systems metabolism. Brit J Surg 2010, 97:80-80.

130. Kinross J, Seitz A, Prabhudesai S, Roberts G, Kenn H, Nicholson J, Ziprin P, Darzi A: Metabolic profiling of FGF-2 induced chemo-resistance in a sw620 colon cancer cell line. Brit J Surg 2008, 95(7):937-937.

131. Eftychios Manoli; Afeez Adebesin; Zsolt Bodai; Julia Balog; Hiromi Kudo; Steven Pringle; Robert Goldin; Ara Darzi; Jamie Murphy; James Kinross; Zoltan Takats. Near Real-Time Diagnosis of Omental Metastases in Patients with Primary Colorectal Cancer Using Rapid Evaporative Ionisation Mass Spectrometry (REIMS). ASMS, San Diego 2018.

132. Mason SE, Alexander J, White E, Bodai Z, Manoli E, Paizs P, Scott A, Adebesin A, Hoare J, Goldin R, Darzi A, Takats Z, Kinross JM. Prospective observational cohort study of rapid evaporative ionization mass spectrometry (REIMS) for near-real time diagnosis and stratification of colorectal cancer. DDW 2018, Washington.

133. Petra Paizs, Eftychios Manoli, Sam E Mason, James Alexander, Zsolt Bodai, Emma White, Afeez Adebesin, Jonathan Hoare, Robert Goldin, Ara Darzi, James M Kinross, Zoltan Talkats. Rapid evaporative ionisation mass spectrometry (REIMS) analysis of the mucosal lipidome has a high diagnostic accuracy for adenomas and early colorectal cancer. ASMS, San Diego 2018.

134. *Poynter, L. Mirnezami, R. Soares, R. McKenzie, J. Patel, P. Peppa, N. Mirnezami, A. Kinross, J. Darzi, A. Takats, Z. Modulation of cellular phospholipids correlates with tumor regression grade and radio resistance in rectal cancer. 109th Annual AACR meeting, Chicago 2018.

135. Petra Paizs, Eftychios Manoli, Sam E Mason, James Alexander, Zsolt Bodai, Emma White, Afeez Adebesin, Jonathan Hoare, Robert Goldin, Ara Darzi, James M Kinross, Zoltan Talkats. Rapid Evaporative Ionisation mass spectrometry (REIMS) analysis of the mucosal lipidome has a high diagnostic accuracy for adenomas and early colorectal cancer. 109th Annual AACR meeting, Chicago 2018.

136. Manuela Salvucci, Liam Poynter, Reza Minerzami, Steven Carberry, Robert O’Byrne, Mattia Cremona, Bryan T. Hennessy, Kirill Veselkov, James Kinross, Jochen H. M. Prehn. Integrated multi-layer analysis reveals novel insights into the molecular landscape of colorectal cancer (CRC). 109th Annual AACR meeting, Chicago 2018.

137. Mason SE, Alexander J, White E, Bodai Z, Manoli E, Paizs P, Scott A, Adebesin A, Hoare J, Goldin R, Darzi A, Takats Z, Kinross JM. Chemical endoscopy of mucosal lipids permits near real time identification of poor prognostic features in colorectal cancer. EAES, London 2018.

138. Poynter, L. Mirnezami, R. Soares, R. Kinross, J. Mirnezami, A. Peppa, N. Goldin, G. Takats, Z. Darzi, A. Mass Spectrometry Imaging Reveals Lipidomic Biomarkers of Radioresistance in Rectal Cancer. 12th European Colorectal Congress (ECC) 2018, St. Gallen.

139. Huq T, Alexander J, Cameron S, Takats Z, Kinross J. Automated high-throughput colorectal cancer biomarker screening using Rapid Evaporative Ionisation Mass Spectrometry (REIMS). ASGBI –2018, Liverpool.

140. Manuela Salvucci, Irene Llorente-Folch, James Kealey, Federico Lucantoni, Steven Carberry, Natalia Niewidok, Robert O’Byrne, Liam Poynter, Reza Minerzami, Chanthirika Ragulan, Gift Nyamundanda, Caoimhín G. Concannon, Kirill Veselkov, Anguraj Sadanandam, James Kinross, Heiko Düssmann, Heinrich J. Huber, Jochen H.M. Prehn1. “Systems modelling in the decoding and targeting of metabolic programming in cancer”. Cold Spring Harbor Laboratory Cell Death Conference, NY. August 2017

141. * James Alexander, Louise Gildea, Julia Balog, Abigail Speller, James McKenzie, Laura Muirhead, Alasdair Scott PhD, Christos Kontovounisios, Shanawaz Rasheed, Julian Teare MD, Jonathan Hoare PhD, Kirill Veselkov, Robert Goldin, Paris Tekkis, Ara Darzi, Jeremy Nicholson, James Kinross, Zoltan Takats. A novel methodology for in vivo endoscopic phenotyping of colorectal cancer based on real time analysis of the mucosal lipidome: A prospective observational study of the iKnife. SAGES, Boston 2016.

142. Veselkov K, Mirnezami R, Claude E, Kinross J, McKenzie J, Inglese P, Neeson K, Langridge J, Holmes E, Takats Z et al: Translational Data Analytics for Large Mass Spectrometry Imaging Datasets in Clinical Research. ASMS, June 5th to 9th 2016; San Antonio; 2016.

143. Alexander J, Gildea L, Balog J, Speller A, Mroz A, Scott A, McKenzie J, Veselkov K, Goldin R, Kinross J et al: Development of a Novel Rapid Evaporative Ionisation Mass Spectrometry (REIMS) Platform 'iEndoscope' for In Vivo Chemical Histology During Colonoscopy. ASMS, San Antonio; 2016.

144. Veselkov K, Mirnezami R, Strittmatter N, Kinross J, Speller A, Abramov T, McKenzie J, Jones E, Darzi A, Goldin R et al: Translational Bionformatics Platform for Next Generation Histology by Imaging Mass Spectrometry. In: 62nd Conference of the American Society for Mass Spectrometry. Baltimore; 2014.

145. Takats Z, Strittmatter N, Jones EA, Mirnezami R, Speller A, Goldin RD, Muirhead L, Kinross J, Abbassi-Ghadi N, Golf O et al: Celebrating DESI – the First 10 Years and Perspectives for the Next Decade: From Automated Histopathology to Understanding Cancer Lipid Biochemistry. In: 62nd Conference of the American Society for Mass Spectrometry. Baltimore; 2014.

146. Takats Z, Strittmatter N, Balog J, Huang F, Kinross J, Kumar S, Hansel T, Jones E: Keynote: Direct mass spectrometric analysis of mucosal membranes – experimental approaches and applications. In: 20th International Mass Spectrometry Conference. Geneva; 2014.

147. Muirhead L, Balog J, Kinross J, Guallar-Hoyas C, Speller AVM, Goldin R, Nicholson JK, Darzi A, Takats Z: The iknife: near real time

intraoperative identification of colorectal cancer and adenomatous polyps using rapid evaporative ionisation mass spectrometry (REIMS). In: Tripartite Colorectal Meeting 2014. Birmingham; 2014.

148. Golf O, Kermani NZ, Guenther S, Goldin RD, Kinross J, Speller AVM, Takats Z, Veselkov K: Automated Classification and Visualization of Histological Features by Mass Spectrometry Imaging;. In: 62nd Conference of the American Society for Mass Spectrometry. Baltimore; 2014.

149. A.J. S, Mason SE, Arunakirinathan M, Reissi S, Kinross J, Smith J: Risk-stratification of patients with suspected appendicitis can improve the diagnostic value of imaging and reduce the negative exploration rate. In: ASGBI. Harrogate; 2014.

150. Patel V, Lee H, Taylor D, Aggarwal R, Kinross J, Darzi A: Virtual worlds are an innovative tool for medical device training in a simulated environment. In: Medicine Meets Virtual Reality 19: 2013; Los Angeles: IOS Press; 2013.

151. Kinross J, Drymousis P, Jimenez B, Frilling A: Metabonomic profiling - A novel approach in neuroendocrine neoplasms. In: UKI NETS 11th National Conference: 25th November 2013 2013; The Royal College of Physicians of London; 2013.

152. *D Cohen D, Sevdalis N, Favara D, Petrucci A, Prime M, Ilyas U, Kinross J, Howell AM, Bagnall M, Kulendran M et al: Global Trauma Team Leader Training And Assessment Using Virtual Worlds - A Feasibility and Realiability Study Across 3 Continents. In: Association for Surgical Education. Orlando, Florida; 2013.

153. Shion H, A.Vorkas P, Mirnezami R, Lewis MR, Kinross J, Cloarec O, Spagou K, Want EJ, Goldin R, Murrey N et al: Metabolic characterisation of tumour-tumour microenvironment interactions in human colorectal cancer using MALDI mass spectrometry imaging - May 23, 2012. In: 61st Conference of the American Society for Mass Spectrometry. Vancouver; 2012.

154. Sasi-Szabo L, Muirhead L, Kinross J, Dezso B, Balog J, Damjanovich L, Takats Z: Large Scale Clinical Testing of Rapid Evaporative Ionization Mass Spectrometry-based Intraoperative Tissue Identification In: 61st Conference of the American Society for Mass Spectrometry. Vancouver; 2012.

155. Randhawa S, Mirnezami R, Jimenez B, Kinross J, Beckonert O, Merrifield C, Holmes E, Nicholson J, Darzi A: Metabolic Profiling of Urine Reveals Distinct Phenotypic Changes in Patients Undergoing Colorectal Excision. In: SAGES. San Diego; 2012.

156. Kinross J, Deville E, Alkhamesi N, Barton R, Silk D, Holmes E, Goldin R, Gibson G, Nicholson J, Darzi A: A top down systems biology analysis reveals gut microbial modulation influences the metabolic response to intestinal ischaemia / reperfusion injury. In: European Surgical Association. Hamburg; 2012.

157. Kinross J, Deaville E, Barton R, Silk D, Goldin R, Holmes E, Nicholson J, Darzi A: Galactooligosaccharide (GOS) prebiotic supplementation increases the severity of injury after intestinal ischaemia / reperfusion (I/R) injury: analysis by global metabolic profiling in a rat model. In: International Surgical Week. Tokyo. ; 2011.

158. Kinross J, Deaville E, Barton R, Silk D, Goldin R, Holmes E, Gibson G, Darzi A, Nicholson JK: A Global Metabolic Profiling Analysis of the Gut Microbiome after Surgically Induced Gut Injury. In: International Human Microbiome Congress. Vancouver; 2011.

Books and book chapters

159. Jia L, Ashrafian H, Bueter M, Kinross J, Sands C, Le Roux C, Bloom S, Darzi A, Athanasiou T, Marchesi J et al: Metabolic Surgery Profoundly Influences Gut Microbial Host Metabolic Crosstalk. In: International Human Microbiome Conference. Vancouver; 2011.

160. Roon ACv, Maher AD, Wang Y, Swann JR, Kinross J, McLaughlin S, Paraskeva PA, Ara W. Darzi, Nicholson JK, Holmes E et al: Metabonomic Approach Using Proton Nuclear Magnetic Resonance Analysis of Human Blood Plasma Reveals Increased Levels of α-1 Acid Glycoprotein (Orosomucoid) in Pouchitis. In: European Society for Coloproctology. Sorento; 2010.

161. Atkin G, Suleman A, Kinross J, Vaizey CJ: Patient characteristics and treatment outcome in functional anorectal pain. . In: Association of Coloproctologists of Great Britain and Ireland. Bournmouth; 2010.

162. Kinross J, Taylor D, Darzi A: Second Life: The imperial College experience. National Association of Medical Simulators. In: National Association of Medical Simulators Manchester, UK. ; 2009.

163. Kinross J, Umrani I, Taylor D, Woo K, Arora S, Sevdalis N, Aggarwal R, Kneebone R, A. D: The surgical metaverse: Using virtual worlds to enhance medical student training in the operating theatre. In: Society of Academic Research Surgeons (SARS - Patey Prize Session). Bristol 2009.

164. Kinross J, Taylor D, A. D: Second Health: Health Care Strategy In The Virtual World. . In: Medicine Meets Virtual Reality. Los Angeles; 2008.

165. Kinross J, Barton RH, Hunte KD, Tuohy KM, Alkhamesi N, Goldin R, Silk D, Holmes E, Nicholson JK, Darzi A: Surgical Supersystems: Metabonomic Profiling of the Gut Microbiome During Surgically-Induced Ischaemia / Reperfusion Injury. In: 9th International Conference on Systems Biology. Gothenberg; 2008.

166. Kinross J, Barton R, Alkhamesi N, Hunte K, Tuohy K, Silk D, Holmes E, Darzi A, J N: Surgical supersystems: Metabolic profiling of acute intestinal ischaemia / reperfusion (I/R) in the rat. In: The Society of Academic and Research Surgery (SARS) Birmingham, Patey Prize session; 2008.

167. Kinross J, Barton R, Alkhamesi N, Paraskeva P, Holmes E, Nicholson J, Darzi A: Metabonomic analysis of the intestinal microbiome during intestinal ischaemia / Reperfusion (I/R) injury. . In: The Association of Surgeons of Great Britain and Ireland (ASGBI) international surgical congress. Bournemouth; 2008.

168. Kinross J, West J, Halls S, Vincent C, Darzi A: Resuscitation events: The Observational Perspective. In: The Eighth congress of the European Resuscitation Council Stavanger, Norway.; 2006.

* Prize winning abstracts

I am the editor for Clinical Surgery, to be published by Elsevier in 2020.

1. Kinross, J. Clinical diagnosis and prognosis In metabolic phenotyping. The Handbook of Metabolic Phenotyping. Elsevier 2018. Editors Lindon, Nicholson and Holmes.

2. Kinross, J. Muirhead, L. Takats, Z. Precision surgery and surgical spectroscopy. Metabolic phenotyping in personal and public healthcare. Editors, Elaine Holmes, Jeremy Nicholson, Ara Darzi and John Lindon. Feb 2016. Elsevier, Academic Press.

Other publications

Invited talks and keynotes

3. Kinross. J, Marchesi, J. The Aging Superorganism. Metabolic phenotyping in personal and public healthcare. Editors, Elaine Holmes, Jeremy Nicholson, Ara Darzi and John Lindon. Feb 2016. Elsevier, Academic Press.

4. Kinross, j. Darzi, A. An introduction to animal research. Key topics in Surgical Research and Methodology. Editors Athanasiou, A. Debas, H. Darzi, A. Springer. 2010.

5. Kinross, J. Ziprin P. Colorectal cancer. ‘Hospital Surgery, Foundations in surgical practice.’ Editors: Aziz O, Purkayastha S, Paraskevas P. Cambridge university press. 2009.

6. Kinross, J. Ziprin P. Diverticular disease. ‘Hospital Surgery, Foundations in surgical practice.’ Editors: Aziz O, Purkayastha S, Paraskevas P. Cambridge university press. 2009.

7. Kinross, J. Ziprin P. Volvulus. ‘Hospital Surgery, Foundations in surgical practice.’ Editors: Aziz O, Purkayastha S, Paraskevas P. Cambridge university press. 2009.

I have illustrated the following complete surgical and academic textbooks.

1. Hospital Surgery: Foundations in Surgical Practice. Cambridge university press. 2009. Edited by Omer Aziz, Sanjay Purkayastha and Paraskevas Paraskeva

2. An Introduction to Body Sensor Networks. Aziz O, Lo B, Darzi A, Yang GZ. Body Sensor Networks. May 2006. Springer-Verlag London Ltd

I have illustrated the following peer reviewed publications:

1. Prabhudesai SG, Rekhraj S, Roberts G, Darzi AW, Ziprin P. Apoptosis and chemo-resistance in colorectal cancer. J Surg Oncol 2007;96(1): 77-88.

2. Riga C, Bicknell C, Jenkins M, Hamady M. Coil Embolization of an Aneurysmal Type B Dissection Persistent False Lumen after Visceral Hybrid Repair. J Vasc Interv Radiol 2008.

3. Leff DR, Orihuela-Espina F, Atallah L, Athanasiou T, Leong JJ, Darzi AW, Yang GZ. Functional prefrontal reorganization accompanies learning-associated refinements in surgery: A manifold embedding approach. Comput Aided Surg 2008: 1-15.

In addition to the international and national presentations and posters referenced above, I have been an invited speaker or delivered a keynote address at the following conferences:

1. Kinross J. Mixed Reality. CogX, London June 2020. 2. Kinross J. How surgeons will use data to inform intra-operative decision

making. Intelligent Health. London, September 2020. 3. Kinross J. The oncogenic microbiome – defining drivers and passengers

in initiation and progression. The London Microbiome Meeting.

October 2020. 4. Kinross J. Leveraging the gut microbiome to improve clinical outcomes

in cancer. Auckland, New Zealand. October 2020. 5. Kinross J. How the microbiome will change colorectal surgery.

International Bordeaux Colorectal Master Class. October 2020. 6. Kinross J: Leveraging the gut microbiome to improve clinical outcomes

in cancer. New Zealand Society of Oncology. October 2020. 7. Kinross J. The Digital Surgeon. Association of Colorectal and

Proctological Surgery. Edinburgh, September 2020. 8. Kinross J. Listening to the patient’s gut. The power of patient generated

data. Royal Society of Medicine. May 2020. 9. Kinross J. Translational applications of the oncological microbiome in

clinical practice. Stellenbosch University Microbiome Meeting. Stellenbosch, South Africa. November 2019.

10.Kinross J. Translational applications of the gut microbiome in surgery. The Dutch Surgical Society, Edinburgh September 2019.

11.Kinross J: Digital surgery in precision colorectal therapy: Indian Medical Association, November 2019 Cochin, India.

12.Kinross J. Incorporating microbiome sciences into the surgical management of cancer. American College of Surgeons Meeting: San October Francisco 2019.

13.Kinross J. The gut microbiome in the age of personalised medicine. Complexities in coloproctology. RSM, London August 2019.

14.Kinross J. The iKnife – Translational systems biology in the operating room. South African Colorectal Society, Johannesburg. June 2019.

15. Kinross J. African dietary-microbiome interactions and the rising prevalence of colon cancer. South African Colorectal Society, Johannesburg. June 2019.

16.Kinross J: iKnife – towards chemically driven robotic systems. Ai and Medical Robotics. London Feb 2019.

17.Kinross, J. Clinical studies of the gut microbiome and colorectal cancer causation and pharmacomicrobiomics in practice. Microbiome Movement Conference, Paris, Jan 28th 2019.

18.Kinross, J. The gut microbiome and personalized healthcare in surgery. SARS, RSM 8th Jan 2019.

19.Kinross, J. Molecular biology in rectal cancer – the elephant in the room? Controversies in rectal cancer, Cambridge, Dec 12th, 2018.

20.Kinross, J. Is it all about bacteria? The role of the microbiome in the development of rectal cancer St. Mark’s frontier’s conference, 29th

November, 2018. 21.Kinross, J. Preoperative oral antibiotics in elective colorectal surgery.

RSM Coloproctology. Nov 22nd, 2018. 22.Kinross, J. The gut microbiome and colon cancer: Passenger or driver?

Wellcome Genome Campus- Exploring Human Host-Microbiome Interactions in Health and Disease, 6th December, 2018.

23.Kinross, J. Real Time mapping of the Colonic Mucosa Using REIMS. Union Hospital Tongji Medical College Huazhong University of Science and Technology, International Forum of Functional Gastrointestinal Disorders, Wuhan, 2018.

24.Kinross, J. Augmenting Surgical Reality. Microsoft UK Healthcare Innovation Summit - London 6th June

25.Kinross, J. The Surgical Microbiome: How the gut microbiome influences surgical outcomes. The microbiome: manipulation, application and reaction. RSM, June 19th. 2018.

26.Kinross, J. Superorganism surgery: The microbiome and anastomotic

health. J+J Anastomotic Leaks Conference 2018, Hamburg. 27.Kinross, J. Novel methodologies for studying metabolic signaling in gut

inflammation. AMC Gut inflammation and metabolism Symposium – Amsterdam, September 8th 2017

28.Kinross, J. Cybersecurity in the NHS. PETRAS IoT Research Hub Workshop - Securing Health IoT. June 29th, 2017.

29.Kinross, J. Oncomicrobiome: Precision healthcare in cancer. House of Commons Science and Technology Committee, House of Commons, March 5th, 2018.

30.Kinross, J. Precision surgery: Translational applications of ambient mass spectrometry in the operating room. ASMS, Asilomar, California September, 2017

31.Kinross, J. The Gut Microbiome and Personalised Gut Health. AMC gastroenterology meeting

32.Welsh Association of Gastroenterology, Cardiff. May 201733.Kinross, J. The gut microbiome: Colon cancer aetiology and

personalised surgical oncology. Arab Health Week, Dubai. January 2017.

34.Kinross, J. Serious Games for Healthcare in the UK: Its Potential & Challenges. Singapore Health and Biomedical Congress, September 2016.

35.Kinross, J. Translational Systems Medicine And Precision Surgery. London, Feb. 2016. 2016 Chief Scientific Officer's Healthcare Science Event

36.Kinross, J. Gut Microbial Metabolic Signaling In Inflammation And Cancer. DDW, San Diego. May 2016.

37.Kinross, J. The iKnife: Translational metabolic phenotyping for precision surgery. 4th Annual Workshop on Metabolomics. July 19th

2016. University of Alabama, USA.38.Kinross, J. Serious Games for Healthcare in the UK: Its Potential &

Challenges. Singapore Health and Biomedical Congress, September 2016.

39.Kinross, J. Gut Microbial Metabolic Signalling In Inflammation And Cancer. DDW, San Diego. May 2016.

40.Kinross, J. The iKnife: Translational metabolic phenotyping for precision surgery. 4th Annual Workshop on Metabolomics. July 19th

2016. University of Alabama, USA. 41.Kinross J. Molecular Phenotying in Surgical Environments SIASTOK

( Semmelweis University, Department of Anaesthesiology and Intensive Care Medicine) - March 2015.

42.Kinross J. - Operative Systems Medicine: Rapid Evaporative Ionisation Mass Spectrometry (iknife) in Oncological Surgery. Cleveland Clinic Surgical Innovation lectures March 2015.

43.Kinross, J. The Colon Cancer Microbiome. ConMet – Microbiomes and Metagenomes. Shard, London. March 2015.

44.Kinross, J. Surgical Systems Biology: From the iKnife to Augmented Histology. Royal College of Surgeons of Ireland, Charter day. Febuary 2015.

45.Kinross, J. Surgical applications of metabonomics – LAMPS Network (Latin American Metabolic Profiling). Lima, Peru May 2014.

46.Kinross, J. Dysbiosis in Colon Cancer British Society of Gastroenterology Work Shop, London April 2014.

47.Kinross, J. “Surgical applications of systems medicine” Clinical and Pharmaceutical Solutions Through Analysis. 2013, Philadelphia.

48.Kinross, J. Are variations in the metabonome associated with

Research

colon cancer risk? AGA Research Symposium, DDW . May 2013. Orlando Florida.

49.Kinross J. Applying an established technology (metabonomics) in critical care. UK critical care research forum July 2013. London

50.Kinross J. Personalised phenotyping in cancer: ‘The bacteriome and cancer’ National Cancer Research Institute (NCRI) cancer Conference. November 2013, Liverpool.

51.Kinross J. Virtual Worlds Technology Enhances Medical Student Training In The Operating Room. Key note. MMVR, Jan. 2009. Long beach, California.

52.Kinross J (Invited panellist). A virtual world as a healthcare information platform. American Medical Informatics Association, Washington, Nov 2008.

53.Kinross J. Metabonomic profiling of the gut microbiome: Implications for human health. Metagenomics Nov. 2008, University College San Diego.

54.Kinross J. Metabonomic Applications in Food Technology and Nutrition. Nutrigenomics 2008, Combined meeting of The European Nutraceutical Institute (ENI), The International Society of Antioxidants in Nutrition & Health (ISANH), The International Society on Preventive Medicine (ISPM), The French Society for Antioxidants (SFA), The Japanese Society for Antioxidants (JSA) and The University of Malta. March 13-14 2008, Paris.

55.Kinross J, Darzi A. Second Health: Operating in Second Life. The Royal College of Surgeons of England Annual Education Conference September 2007.

I am a clinical scientist with an interest in translational systems medicine. I have experience of laboratory and animal research and of clinical trials. My research has been in the following areas:

PhD 2010 - Metabolic profiling of intestinal ischemia / reperfusion injury. Supervisors, Profs. Darzi and Nicholson.

Primary research interests:1. Translational computational biology and metabonomics. I am PI

on the NIHR i4i iEndoscope project, that is developing a novel methodology for real time adenoma phenotyping based on ambient mass spectrometry. As part of this work, we are developing robotic and minimally invasive applications of this technology for endoluminal and surgical applications.

2. Gut microbiome and colorectal cancer aetiology and therapy: My group is studying the microbiome in three areas: 1) cancer driver / passenger hypothesis in colorectal cancer. Specifically, we are performing both human and animal studies to determine mechanistic relationships between the gut mucosal microbiome and cancer. 2) As part of this work we are also studying the to map the evolution of the gut microbiome in indigenous populations at extreme low risk (rural African) and high risk (native Alaskan people) as they migrate to developed cities and western environments. The aim is to establish gut microbial-nutritional interactions that confer cancer risk and which will serve as biomarkers of early cancer formation in ethnic subgroups. 3) Regulation of mucosal healing and response to therapy after surgery for colon cancer.

Current biomarker trials:1. PI - MECANO Trial: £182,000 Commercially funded multicenter,

prospective observational study for the development of blood based metabolic biomarkers for the early detection of CRC and complex adenomas.

2. PI – Faecal REIMS and the NICE-FIT study – we are analyzing if mass spectrometry analysis of FIT samples in a screening population can improve diagnostic accuracy.

3. Co-I: Tracking mutations in cell free tumour DNA to predict Relapse in eArly Colorectal Cancer (TRACC study). Chief Investigator: Prof. David Cunningham, Royal Marsden NHS Foundation trust.

4. BRC (£20K) REIMS FIT (PI) testing augmentation: Development of novel biomarkers for screening of colorectal cancer based on lipidomic analysis of faecal samples.

Intervention trials:1. Co-I: Diet, the microbiota and its metabolites in colon cancer risk

in Alaska Native People. A fibre supplement dietary interevention trial for reducing adenoma risk.

2. Co-I: Faecal Microbiota Transplant in Ulcerative Colitis (Fmtuc) - a Phase II Single-Blind Randomised Clinical Trial (NIHR funded).

Surgical trials and imaging studies1. VEGAS trial (Local PI) – Commercial trial of powered circular

stapler for rectal anastomosis. Due to start September 20182. STAR-TREC (Local PI) – Management of early rectal cancer. 3. PRESERVE trial (Co-I): MRI staging for organ preservation in

early rectal cancer (PI Prof. Brown).

Secondary research interests:1. Cybersecurity and patient safety: I have lead work to define

vulnerability in the NHS’s digital cybersecurity posture. As part of this analysis we have lead several work shops and published critical analysis of the Wanna Cry attack on NHS performance.

2. Big data and machine learning: I am developing machine learning approaches for the real time analysis of social media platforms for the early detection of road traffic injuries.

3. Virtual worlds for surgical and trauma education: I am coordinating a research collaborative between the UKs centre for defense medicine and the Swedish Armed Forces Centre for Defense Medicine, The Royal College of Surgeons, Karolinska Institutet, University of Gothenburg and Sahlgrenska University Hospital. The aim is to create digital blended learning environments for scalable training in major incident and mass causality scenarios.

4. Augmented reality and surgical education: I am developing AR systems using the HololensTM platform for intra-operative anatomy visualization.

PhD Supervision:

Education and training

1. Primary supervisor James Alexander – AwardedSam Mason (CRUK research fellow, Year 1) – Polyp progression. Nikhil Ladwa (St. Mark’s, Year 1) - intestinal failure.James Lewis – Surgical Microbiome and anastomotic health.

2. PhD Co-Supervisor Reza Mirnezami (Awarded 2014)Laura Muirhead (Awarded 2017)Grace Barker – (Stratigrad, Yr 1) Nutrition, the microbiome and CRC. Duncan Roberts – (Stratigrad Yr 1) IBD Cancer Tanja-Eslamlou – (Stratigrad Yr 1) Microbiome and metastatic colorectal cancer. Rhea Harwood (Amanda Cross, Yr 1), CRC epidemiology.Seema Yalamanchili (S+C Yr 1), Big data and trauma.

MD Co-supervision. Annabel Shaw – PRESERVE trial (co-supervised with Gina Brown).Theo Georgiou-Delisle - NICE FIT study

MSc SupervisionI have supervised two MSc health design students (Philippa Batey, Annie McKirdy)Amanda Stafford – Rectal cancer microbiome (Distinction)

BSc Supervision (9 supervised in total)2018 Petra Paizs – Validation of faecal REIMS for CRC detection2017 Tausif Huq - Method development for faecal REIMS2016 Ryan Preece – iEndoscope method development.

Early and Late stage reviews:I have completed 10 for members of the department.

PhD / MD Examiner:I have examined Dr. Sarah Huff’s PhD at Imperial. MD examiner for Nick Battersby External MD examiner for Anglia Ruskin UniversityExternal MD examiner for Exeter University.

Weekly departmental PhD Group meeting lead – pastoral care for department’s PhD students and CRF.

PGEC Rep I am a full PGEC rep.

Mentorship: Mentoring – I was selected to take part in the Imperial College mentoring pilot run by the Department of Surgery in 2008. As part of this process I was mentored by the Chief Executive of an NHS Foundation trust at the Department of Health, and I was able to attend executive board meetings chaired by the Chief Executive of the NHS at the DH. I currently mentor Alasdair Scott (Post doctoral ACF) and I am mentored by Prof. Clare Lloyd.

Teaching:

Courses and post graduate education

External examiner

Conferences and

1. MSc – surgical innovation. I teach on advances in laparoscopic technology.

2. MEd in Surgical Education – social media and education3. Surgery BSc – advances in laparoscopic surgery4. Health design MSc: Module 1 lectures. 5. Surgical Finals Lectures 2015-186. Ward teaching for Year 3 and Year 6 medical students7. London surgical skills workshops8. Metabonomics short course lectures: 2010 to 2017.9. Basic surgical skills course instructor10. Anastomosis short course 2014: I was part of the faculty on the

surgical anastomosis course at the ICENI centre in Colchester. This involved practical demonstrations on how to perform both stapled and hand sewn anastomoses.

11. GP basic surgical skills course 2014: I was part of the faculty on a basic surgical skills course targeted at GPs at the ICENI centre in Colchester.

Undergraduate and post-graduate education lead for department of surgery: As part of this I server as a clinical and educational supervisor to F1s and I have instigated a weekly journal club and formal educational forum.

Examinations: Examiner, surgical Finals OSCEs 2017, 2018 and 3rd year PACES in 2006, 2008, 2012, 2013 and 2014-18.

ACF /ACL interview panel 2015 to 2018.

Hackathons1. Digital gaming (Microsoft) – founder and coordinator. March

2018. 2. Blockchain – Speaker.

Medical student question time: Chaired the panel session for medical students considering a career in surgery 2017 and 2018.

Prizes: Nominated Student Academic Choice Award - 2018.

Surgery BSc Co-director. This year I coordinated the curriculum and I delivered a module on surgical innovation and the iKnife.

Healthcare Design MSc. I lead Module 1 of this course and I delivered teaching for the design students as part of this opening module.

I am an external examiner for Anglia Ruskin University on their surgery and gynaecology BSc

Faculty: Controversies in Rectal Cancer meeting, ICENI centre, Colchester, October 2017Faculty: Future Horizons: 4th International Colorectal Cancer Symposium,

meetings

Management, administration, policy and leadership

Journal peer review

London, RSM, 26th April 2018Faculty: Johnson and Johnson Anastomotic Leak Conference – Hamburg 2018.

International Cancer Microbiome Meeting: Founder member and director of the inaugural meeting at the RSM September 2017 and round table discussion on position statement of microbiome and cancer.

London Surgical Symposium – LSS. I am the director for this annual free educational meeting for trainees and medical students, now in its 12th year. We have grown registrations from 120 in 2015 to 350 by 2018.

1st Health cybersecurity workshop: Coordinator and founder member. April 2017.

Coordination and organisation of the Department of Surgery and Cancer Christmas Research Meeting 2015-18.

WISH 2012: I was part of a team from the division of surgery that supported the World Innovation Summit for Health (WISH), in London 2012. This is a global healthcare community dedicated to capturing and disseminating the best evidence-based ideas and practice, attended by the Prime Minister.

Council Member – AGA Nutrition, metabolism and obesity council. Imperial - CRUK Centre: Theme 1 Co-Chair. Centre for wound regeneration (CORE): Theme lead, Early diagnosis of

complications. AHSC Prevention and Early Detection of Colorectal Cancer group

member. NIPCOM committee member for the trust. Imperial-NIHR Clinical Phenotyping Centre Strategy and Oversight

Committee. NIHR-MRC National Phenome Centre Analytical committee Committee member: European Network Workshop on Systems Medicine. NIHR Leadership support and development program (2013/14) London General surgery Leadership Group 2014: This multidisciplinary

committee informed the strategic direction of the London General Surgery Clinical Network.

‘Framework for Action’ report commissioned by Healthcare for London in 2006. I was involved in the consultation process and responsible for developing novel approaches for public engagement, communication and visualisation of health policy. Consulting the Capital ran from November 2007 to March 2008 and received over 5,000 responses from individuals and organisations, including a huge number of responses from traditionally under-represented groups. As a direct extension of this work I was also involved in the delivery of the NHS white paper “High Quality Care For All”.

Annals of surgeryGutNature Reviews in Gastroenterology

Grant peer review

Media and public engagement.

Other achievements and interests

Critical Care MedicinePersonalised medicineJournal of Parenteral NutritionJournal of proteome research

The Intensive Care SocietyNIHR – Research for Patient BenefitWellcome trustEPSRC

Channel 4: Live Well For Longer 2018. Interview on Microbiome and probiotics in healthcare.

BBC Click 2018: Magazine piece on Hololense and augmented reality in Surgery

Ecancer TV 2018: https://ecancer.org/video/6329/goals-of-the-international-cancer-microbiome-consortium.php

Imperial Science Festival 2018 – I ran an iknife stand for public engagement

BMJ Podcast - Wannacry: 2018 https://soundcloud.com/bmjpodcasts/james-kinross-and-chris-hankin-wanncry-about-nhs-it

Countercurrent podcast: Roger Kneebone: 2018 https://itunes.apple.com/au/podcast/countercurrent-conversations-professor-roger-kneebone/id1121211583?mt=2

Royal Hospital School, Essex: School outreach. Lecture on how to get into medical school, and judge of year 8 science price.

BBC 2: Trust Me, I'm A Doctor. Interview on health effects of probiotics. To be broadcast October 2013.

Imperial Science festival: Demonstrated of iknife technology to members of the public using a surgical simulation June. 2013.

Cheltenham science festival: Hosted live demonstrations of our technology for the public. June 8th / 9th 2013

BBC 4: Guts, the strange and mysterious world of the human stomach. Michael Mosley. Presented section on intestinal anatomy. Broadcast Nov. 2012.

NHS Expo – 2008. I presented simulation technology to the public and the secretary of state for health.

Head of school Lepape Marmotte Grandfondo Alpes - 2020 London Park’s Half Marathon 2017 / 18 London Marathon 2006, 2007 and 2013 – Raised £12,000 for Interact

Worldwide, Spinal Research and Beating bowel cancer. The Etape de Tour 2008: Complete an open leg of the tour de France. Captained UH cup winning Imperial Medicals 2nd xv rugby team. Social secretary of Imperial Medicals rugby club. Represented Imperial

medics Rugby Football club at all levels up to 1stXV. Chairman of winter ball committee 1996. Directed medical school soiree 1997. Editor of the rag magazine 1997.

Keen sailor and member of I.S.C. Regularly race laser 4000’s and swallows. Have also represented the south of England sailing team in mirror dinghies.

RYA yacht master theory 2004 Sailing instructor Kite surfer Qualified BSAC sports diver.