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PMC fulltext: Dtsch Arztebl Int. Feb 2009; 106(7): 100105.Publishe !nline Feb 1"# 2009. !i: 10."2"$%&rztebl.2009.0100

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Table 2

Checklist to evaluate the quality of scientific publications

Questions on methodology

Is the study design suited to fulll the aims of the study?

Is it stated whether the study is conrmatory, exploratory or descriptive in

nature?

What type of study was chosen, and does it permit the aims of the study to

be addressed?

Is the studys endpoint precisely dened?

What statistical measure is employed to characterize the endpoint?

Do epidemiological studies, for instance, give the incidence rate of new

cases!, prevalence current number of cases!, mortality proportion of the

population that dies of the disease concerned!, lethality proportion of those

with the disease who die of it! or the hospital admission rate proportion of

the population admitted to hospital because of the disease!?

"re the geographical area, the population, the study period including

duration of follow#up!, and the intervals between investigations described in

detail?

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696241/http://dx.doi.org/10.3238%2Farztebl.2009.0100http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696241/table/T2/http://www.ncbi.nlm.nih.gov/pmc/about/copyright.htmlhttp://dx.doi.org/10.3238%2Farztebl.2009.0100http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696241/table/T2/http://www.ncbi.nlm.nih.gov/pmc/about/copyright.htmlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696241/

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Yes Unclea

r

N

o

Design

Is the &i/ ! the stu cle&rl escribe

Are the stu !ul&ti!n(s) &n the inclusi!n &n e3clusi!n criteri& escribe in et&il

4ere the &tients &ll!c&te r&n!/l t! the ierent &r/s ! the stu

I es:

Is the /eth! ! r&n!/iz&ti!n escribe

&. Is the nu/ber ! c&ses iscusse

b. 4ere suicient c&ses enr!lle (e.*. P!er 50)

Are the /eth!s ! /e&sure/ent (e.*. l&b!r&t!r e3&/in&ti!n# uesti!nn&ire# i&*n!stic

test) suit&ble !r eter/in&ti!n ! the t&r*et 8&ri&ble (ith re*&r t! sc&le# ti/e !

in8esti*&ti!n# st&n&riz&ti!n)

Is there in!r/&ti!n re*&rin* &t& l!ss (res!nse r&tes# l!ss t! !ll!u# /issin* 8&lues)

Stuy inception an i!ple!entation

Are tre&t/ent &n c!ntr!l *r!us /&tche ith re*&r t! /&!r rele8&nt ch&r&cteristics

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Yes Unclea

r

N

o

(&*e# se3# s/!in* h&bits etc.)

Are the r!!uts &n&lze !r ierences beteen the tre&t/ent &n c!ntr!l *r!us

Are sie eects &n &8erse e8ents urin* the stu eri! escribe

"nalysis an evaluation

usin* & checlist such &s this# the st&tistic&l &n /eth!!l!*ic&l s!unness ! & stu c&n be &ssesse &n

i/r!8e/ents c!nsiere.

?!t &ll ! the !ints in this checlist c&n be use t! e8&lu&te &ll stu tes; !r e3&/le# r&n!/iz&ti!n is

&rticul&rl &lic&ble t! clinic&l stuies.

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