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Understanding Mental Illness
Types of DisordersObsessive-compulsive behaviors,
psychosomatic ailments, panic disorders
Psychosis: Person loses contact with realityExamples: schizophrenia, bipolor affective disorder
Treatment Before 1950
Options very limited
Electroconvulsive therapy (ECT) used to treat depression and psychosis
ANTIDEPRESSANTS
TRICYCLICS: Similar to PhenothiazinesMECHANISM OF ACTION: BLOCKS
REUPTAKE OF NOREPINEPHRINE AND SEROTONIN MOOD REFLECTS A BALANCE BETWEEN
NOREPINEPRINE AND SEROTONIN
EFFECTS OF TRICYCLICS
ELEVATION IN MOOD INCREASED PHYSICAL ACTIVITY INCREASED MENTAL ALERTNESS INCREASED APPETITE INCREASED ABILITY TO SLEEP
Zoloft Most popular Antidepressant Used for depression and obsessive-
compulsive disorders, and panic disorders
Approved for use with children
PAXIL
The most heavily advertised antidepressant drug between 1999-2003.
Excellent patient response-59% believed that the drug was beneficial
Paxil negtive responses include
-21% felt drowsiness or disorientation-53% experienced decreased sexual interest-22% gained weight
FDA has concerns that children taking Paxil are 3.2 times more likely to attempt suicide
PaxilCR
PaxilCR is a derivative of Paxil with a a positive patient response especially for social anxiety disorder, panic disorder and premenstrual syndrome.
PaxilCR is about 1/3 of the cost of Paxil
Lithium
Lithium is effective for acute mania and for preventing mania and depression from recurring
Lithium has multiple side effects including nausea, thirst, excessive perspiration and hand tremors
Few withdrawal symptoms
MAJOR TRANQUILIZERS
“ANTI-PSYCHOTIC DRUGS” Phenothiazines (Thorazine)MENTAL HOSPITAL ADMISSIONS
DECREASED SIGNIFICANTLY AFTER THE INTRODUCTION OF MAJOR TRANQUILIZERS
MEDICAL BENEFITS
DECREASED ANXIETY DECREASED MANIA DECREASED DEPRESSION DECREASED STAY IN MENTAL
HOSPITALS