Cardiovascular System-Pathology Lab

3rd year medical studentsDr. Nisreen Abu Shahin

Amniotic fluid embolus: keratin and fetal squamous cells in pulmonary arterioles

Two pulmonary arterioles for women died following delivery Before delivery she developed: (important) 1-DIC 2-coma 3-seizure then she die

lymphedema• Name major

types.• Give examples

on causes

Q1 Primary :congenital Secondary:obstruction Q2: infection(filariasis),fibrosis,radiation,surgical removal of lymph node(breast cancer removal of axillary lymph node)

• Name this vascular condition. Mönckebergmedial calcific sclerosis

• Mention effect on bloodsupply : No affect = doesn't affect the lumen of artery

Purple deposit in the media :classification deposit

AtherosclerosisName the parts of this atheroma.Describe the composition of each part.Intimal lesion with core lipid and fibrous cap (collagen)

Lipid core: whitish needle shape structures =they are cholesterol clusters

Blue color : collagen (fibrous tissue)

Infarction lung infarction (A), and spleen infarction (B).1- what is the type of the lung infarct?2- what is the type of the splenic infarct?3- what are the differences between them?4- describe the microscopic features you expect to see in A and B.

Red infract

White infract

In Red infract must one of five option occurs: Venus obstruction, sluggish circulation, re-perfusion ,congestive tissue ,dual circulation(lung+small intestine+liver)

A case of sudden mesenteric artery occlusion. This is a picture of the small intestines upon surgery.

What type of infarcts is it? Why?

Infarction

Red infract

Aortic aneurysm -What part of the aorta is involved ?

-Picture A, white arrow?

- picture B?Mural thrombus

abdominal aorta

Rupture

Aortic dissection

The special histochemical stain used here shows elastic fibers in black color. -What does the black star represents?

-Name a major precipitating factor -other disorders associated with it?

Blood inside the media

Marfan disease

:Hypertension

Arteriolosclerosis

-A?- B?- causes?

A:benign hypertension, diabetes, aging B: malignant hypertension only

Hyper plastic Arteriolosclerosis

Hayline Arteriolosclerosis

) Giant Cell (Temporal) Arteritis morphology (arrows)A> granuloma; B> fragmented internal elastic lamina

Vasculitis

Complications of MI-what type of complication is seen in this picture (white arrow).

-Mention the consequences that may follow this.

Ventricular free wall rupture

Hemopericardium and cardiac tamponad

-Is this arecent or old MI? (red arrow).

-What is the post-MI complication seen here?

-potential clinical consequences?

Complications of MI

Heart failure, mural thrombus , arrhythmia

Ventricular aneurysm

Scar takes several week(6-8) =so it is old MI

It is true aneurysm because the wall still contact doesn't rupture

Acute rheumatic heart disease

Aschoff bodies are pathognomonic for rheumatic fever (T-lymphocytes, plasma cells, and macrophages)

Inflammatory lesion composed of: 1-T-lymphocytes 2-plasma cells 3-macrophages