Blood

Exercise 29

Composition of whole blood

Typical Erythrocyte

Sickle Cell

Caused by a base pair substitution of a gene for hemoglobin.It results in a deformation of the erythrocyte under low oxygen tension.

Relative leukocyte composition

A : Picture of bone marrow smear (control); Normal granulocytes and erythroblasts are evident. B : Acute lymphoid leukemia (ALL); There is a marked proliferation of small lymphoblasts.

C : Acute myeloid leukemia (AML); There is a marked proliferation of large myeloblasts. D : Chronic myeloid leukemia (CML); There is a marked proliferation of granulocytes at various stages of maturation.

C. D.

Formed elements

The rest of the formed elements

ABO Groups

1. Wear gloves.

2. Handle only your own blood.

3. Dispose of used lancets immediately by placing them in the sharps container. DO NOT LAY USED LANCETS ON THE LAB BENCHES!

4. Contaminated reusable items (microscope slides, glass stir rods, etc) go into the 10% bleach solution. Disposable items (cotton balls, toothpicks, etc) go into the red biohazard bag.

5. Clean up after yourselves using the bleach solution in the squeeze bottles.Your safety and the safety of your fellow students depends upon good lab practices. These are the types of precautions that you will be expected to practice in your future careers. Now is a good time to get started.

Note: Exercise caution during this entire lab!