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Sigma and Sigma-Aldrich are registered trademarks belonging to Sigma-Aldrich Co. and its a�liate Sigma-Aldrich Biotechnology, L.P.

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GE HealthcareLife Sciences

It’s all the convenience you want in a spectrophotometer, packaged in a portable,

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Experience the NanoVue Plus first hand.

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CLONING & MAPPINGDNA AMPLIFICATION

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PROTEIN EXPRESSION

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GENE EXPRESSION

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UNDERSTANDING CHANGE

New tools to advance epigenetics researchFor over 35 years, New England Biolabs has been committed to understanding the mechanisms of restriction and

methylation of DNA. This expertise in enzymology has recently led to the development of a suite of validated

products for epigenetics research. These unique solutions to study DNA methylation are designed to address some

of the challenges of the current methods. EpiMark™ validated reagents simplify epigenetics research and expand the

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EpiMark™ validated products include:

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• Methyltransferases

• Histones

• Genomic DNAs

To learn how these products can help you to better

understand epigenetic changes, visit neb.com/epigenetics.

Simplify DNA methylation analysis with MspJI

MspJI recognizes methylated and hydroxymethylated DNA and cleaves

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Since 1886 the National Academy of Sciences has presented

awards to honor outstanding contributions to science and to

encourage new and innovative research.

National Academy of Sciences

Congratulates the

RECIPIENTS OF ITS2O11 AWARDS

NAS Public Welfare Medal

Ismail Serageldin

Bibliotheca Alexandrina

Arctowski Medal (Solar Physics)

John W. Harvey

National Solar Observatory

Arthur L. Day Prize and Lectureship (Physics of the Earth)

R. Lawrence Edwards

University of Minnesota

Richard Lounsbery Award (Biology and Medicine)

Bonnie L. Bassler

Princeton University

NAS Award in Chemical Sciences

Stephen J. Benkovic

Pennsylvania State University

NAS Award for Chemistry in Service to Society

Paul J. Reider

Amgen, Inc.

NAS Award for the Industrial Application of Science

(Agricultural Science)

H. Boyd Woodruff

Soil Microbiology Associates, Inc.

NAS Award for Initiatives in Research (Optical Science)

Martin T. Zanni

University of Wisconsin-Madison

NAS Award in Molecular Biology

James M. Berger

University of California, Berkeley

NAS Award for Scientific Reviewing (Economics)

Thomas J. Sargent

New York University

Troland Research Awards (Psychology)

Elizabeth A. Buffalo

Emory University School of Medicine

Joshua B. Tenenbaum

Massachusetts Institute of Technology

Selman A.Waksman Award in Microbiology

Carol A. Gross

University of California, San Francisco

Nominations for the 2012 awards will be accepted through

September 15, 2011. For details visit:

www.nasonline.org/awards

MemberCentral.aaas.org

AAASMemberCentralINTRODUCING

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The exclusive new website for the AAAS member community.

481www.sciencemag.org/products SCIENCE VOL 331 28 JANUARY 2011

Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are

featured in this space. Emphasis is given to purpose, chief characteristics, and availability of products and materials. Endorsement by Science or AAAS of any products or

materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

Electronically submit your new product description or product literature information! Go to www.sciencemag.org/products/newproducts.dtl for more information.

LIFE SCIENCE TECHNOLOGIES

NEW PRODUCTS

AAAS/Science Business Office Feature LIFE SCIENCE TECHNOLOGIES

NEW PRODUCTS

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5-hmC DETECTION KITSThe Quest 5-hmC Detection Kits are the fi rst available products for

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hmC) within DNA. The optimized 5-hmC Glucosyltransferase enzyme

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COMPOUND LIBRARIES Two new compound libraries target areas that are of specifi c interest

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HIGH-PERFORMANCE PIPETTESBenchmarked against leading pipettes, the Transferpette S pipette

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For info: 888-522-2726 www.brandtech.com

EPIGENETIC MAPPING The new CpGenome Turbo kit provides rapid bisulfi te conversion—a

critical fi rst step in mapping the differences in genomic DNA

methylation patterns. Aberrant DNA methylation can result in

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onset of diabetes, cancer, cardiovascular, and other diseases.

The kit reliably converts unmethylated cytosines to uracil in 90

minutes, which is twice as fast as commonly used bisulfi te kits

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the CpGenome Turbo kit allows researchers to examine DNA

from more samples in less time. The kit features a proprietary

conversion reagent that reduces incubation times while retaining

high effi ciency, converting more than 99.9 percent of unmethylated

cytosines to uracil. The kit is also highly sensitive, requiring as little

as 1 ng of DNA. The resulting, modifi ed DNA is pure and ready for

epigenetic mapping by sequencing, microarray hybridization, or

quantitative polymerase chain reaction.

EMD Millipore

For info: 800-645-5476 www.millipore.com

HPLC COLUMNSKinetex XB-C18 and Kinetex C8 bring the advantages of ultrahigh

liquid chromatography performance (UHPLC) within standard HPLC

operating pressures to a growing list of applications. Kinetex core-

shell technology meets researchers’ need to improve results and

increase productivity without large capital expenditures. The new

Kinetex XB-C18 provides a unique selectivity, incorporating two iso-

butyl side chains at the base of the C18 ligand to reduce secondary

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umns, this new Kinetex phase has produced differences in peak

elution order and improved separation of co-eluting compounds.

The new Kinetex C8 phase meets the United States Pharmacopeia

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nology while staying compliant with USP-allowable adjustments.

The new Kinetex core-shell columns are available in two particle

sizes—2.6 µm and 1.7 µm—and in variety of column dimensions.

Phenomenex

For info: 310-212-0555 www.phenomenex.com

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Science Mobile AppNow Available for Android Phones

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Above: Confocal IF analysis of rat cerebellum using β3-Tubulin (D71G9) XP™ Rabbit mAb

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