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Integrated Electroencephalography and Transcranial Direct Current Stimulation Device
Matthew Gray, Aaron Sears and Savannah DewberryUniversity of Alabama at BirminghamClient: Dr. Franklin Amthor
Background: EEG and tDCS● Electroencephalogram (EEG)
○ Measurement of electrical activity in brain
○ Surface electrodes placed on scalp
○ Freq: 1-100 Hz
● Transcranial Direct Current Stimulation (tDCS)
○ DC Current applied to the brain through electrodes
○ Modulates cortical excitability
Higgins (2008)EEG 10/20 Electrode Placement Diagram
Clients• Dr. Franklin Amthor
• Interim Director of Behavioral Neuroscience Graduate Program
• PhD. Biomedical Engineering• Original idea for simultaneous, same-site
recording during tDCS stimulation
• Dr. Mary Boggiano• Associate Professor of Psychology• Studying effects tDCS on cravings• Currently using TCT tDCS Stimulation Kit
• tDCS Only• Behavioral Feedback
Dr. Amthor Dr. Boggiano
Design Need • Transcranial Direct Current Stimulation (tDCS)
• Possible treatment for many various neurological conditions • Depression• Anxiety• Binge-eating
• Physiological effect with respect to neurological conditions not well understood
• Current pharmaceutical treatment isn’t always effective and has many unwanted side effects
Picture?
TCT tDCS Transcranial Stimulation Kit - $349
Existing Solutions• StarStim Neuro Electrics: $10,000+
• Research-class multichannel transcranial current stimulator
• EEG and accelerometry• Contains simultaneous EEG recording during
tDCS.
• Soterix Medical tDCS: $4,500+• Simple Interface• Out-source EEG capability Soterix tDCS
Starstim Neuroelectrics
Device Novelty • Our device goals:
• Provides same-site, simultaneous electroencephalography (EEG) and transcranial Direct Current Stimulation (tDCS)
• Reasonably cheap (<$1000)• EEG Addon capability for TCT tDCS device
• Targeted Users:• Researchers conducting clinical studies
Constraints
Component CostsPart Cost
Arduino Uno $24.95
Electrodes + sponge sleeves $32.27
ADC – ADS1015 $9.95
Ethernet cable $5.89
Operational amplifiers $0.94
Instrumentational Amplifier $20.74
Resistor Kit $7.99
TCT TDCS $349.00
Total $451.73
Overall Device
Data Acquisition Subsystem - Arduino• Switch • Converter - ADS1015• Voltage Offset Circuit• The Arduino has
dedicated SCL (clock) and SDA (data) connections
EEG Subsystem - Circuit DesignStage 1:Filter: 1 Hz High-Pass
Stage 3:Gain: 161xFilters: 1Hz-100Hz Bandpass
Stage 4:Filter: 60Hz Notch
Stage 5:Buffer
Inpu
t
Out
put
Grounding
Stage 2:Instrumentation AmplifierGain: 206.8x
Validation• Comparison
between signals acquired with a commercial EEG (Grass) device and our circuit
Figure 2: PSD plot of signal acquired with Grass EEG machine (right) and our (NeuroVolt) EEG circuit (left).
Figure 1: Raw EEG signal acquired from NeuroVolt EEG circuit (red) and Grass 7D Polygraph (white).
Future Work
• tDCS voltage changes with perspiration, movement, etc. & causes change in voltage.• Some AC Noise from 1 to 18 Hz
• Project is being further developed by Dr. Amthor’s lab for use in Dr. Boggiano’s lab
Figure 3: PCB Layout for our EEG circuit w/ AC Coupling
Acknowledgements• Dr. Amthor• Dr. Boggiano• Dr. Eberhardt• Dr. Dobbs• Mary Katherine Osborne• Carl Stephens
• NIH, NSF, and VentureWell grants