Achievements and future plan on development of good

9th IFDC, Norwich, UK 14-16 September 20111

Achievements and future plan on development of good quality food analysis laboratories among ASEANFOODS

Prapasri Puwastien*, Kunchit Judprasong, Pongtorn Sungpuag, Naruemon Pinprapai

ASEANFOODS Regional Centre, Institute of Nutrition, Mahidol University, Putthamonthon 4, Salaya,

Nakhon Pathom 73170, THAILAND*[email protected]

9th IFDC, Norwich, UK14-16 September 2011


• Brief introduction of ASEANFOODS

• How quality control system was developed in ASEANFOODS?

• How the system has been progressed?

• What are our achievements?

• Activities in the future.

Outline


ASEANFOODS: established in 1986

ASEAN Network of Food Data System

Regional Centre: Institute of Nutrition, Mahidol University

Coordinator: Prof. Dr. Aree Valyasevi (1986-1991),

INMU Director: Prof. Dr. Kraisid Tontisirin (1992-1999);

Assoc. Prof Dr. Songsak Srianyjata (2000-2002),

Assoc. Prof. Dr. Prapasri Puwastien (2003-present)

Member countries:

Indonesia, Malaysia, Philippines,Singapore, Thailand, Vietnam,Myanmar, Cambodia

Brunei Darussalam; Laos


Ultimate goals of ASEANFOODS

To develop national and regional food composition

database with high quality, adequate quantity and

accessibility to the users

Use of food composition data

food composition data

Agriculture

Experimental/clinical,& public health nutrition

Health

epidemiology

Foodproduction

Product testing

Product/processdevelopment

recommendation Nutritionists

Dietaticians

Medical doctors


Food samples & characteristics

Fresh Cooked/processed foods

Identify food items and nutrients to be analysed

Sampling plan and sampling

• Select analytical methods• Check method performance:

method verification or validation• Check analyst’s performance –

precision and accuracy• Quantitative measurement of

nutrients

Good quality food composition data

General process for FCD development

Nutrient analysis in a laboratory

InternalExternal

QC systems

RMs

Samples preparation


How quality control system was developed in ASEANFOODS?

International linkages and collaborations: key factors

- OCEANIAFOODS: since 1989 - attending regional conferences (the 2nd to 5th and the 8th OCEANIAFOODS), presenting activities, exchanging idea, and forming collaboration with various laboratories in Australia, New Zealand and Fiji

- Asia Pacific Food Analysis Network (APFAN): since 1991 (QHSS is the coordinator)APFAN organised 7 hand-on training courses on nutrient analysis for ASEANFOODS and other regions

- AusAID programme 1 (1997-1998): one year project (Australia-Indonesia-Thailand) on “Development of Analytical Quality Assurance for Indonesian Food Laboratories”Thailand was a counterpart country, providing lectures, workshops and hand-on trainings on internal and external quality control system.

Outcome: create collaborations between regions, create awareness on QC system in ASEANFOODS, strengthen analytical performance of laboratories.


“Laboratory quality standards towards global competition: Management Systems, Reference Materials, and Proficiency Testing”

Activities: organising 3 Workshops for ASEANFOODS members in Indonesia, Thailand and Philippines,

using different theme that matched to the main objective

WS in Thailand 17- 21th July, 2006: “Production of reference materials, proficiency testing (PT) and statistical evaluation”*

* Theory and practices: - internal and external quality control system, - hand-on training on test material preparation, - organising PT programme- intensive training on statistical evaluation

*The training strengthened human resources in ASEANFOODS on development of internal and external quality assurance system based on various ISO (ISO/IEC 13528, ISO Guide 34 and 35, ISO 17043 and ISO 5725).

- AusAID programme 2 (2006): “Australasian Workshop”

How quality control system was developed in ASEANFOODS? (continued)


Laboratories in • USA (USDA)

• EUROPE (e.g., UK, Netherlands, Austria, Sweden, Germany)• Canada

ASEANFOODS Laboratories

Internal QC system

Proficiency testing(PT)

Food reference materials AS-FRM

ASEANFOODS

Manual on methods for food analysis

• OCEANIAFOODS• APFAN• AUSAID counterpart

International linkage

Workshop 2002

Other regions

External QC system

How quality control system was developed in ASEANFOODS? (continued)


How the QC system has been progressed?

• Internal quality control system:Self-evaluation of analytical performance using of in-house QC sample tocheck daily analytical performance and monitoring by a control chart

• External quality control system:Evaluation of laboratory performance (Proficiency testing, PT) by an external organisation (ASEANFOODS Regional Centre, being external evalator or PT provider)

Two types of quality control system:


Source of information

% laboratories using

No. Labs

in-house QC

PT RMs CRMsAccredited LabISO/IEC 17025

1998 (PT-3) 18 28 39 6 22 17 (3 lab)

2003 (PT-7) 25 56 100 24 36 36 (9 lab)

2005 (PT-8) 31 77 61 35 45 42 (13 lab)

2010 (PT-9) 23 87 91 74 74 (17 lab)

Analytical quality control system used amongASEANFOODS laboratories

PT: proficiency study; RMs: reference material; CRMs: certified RMs;

How the QC system has been progressed? continued


General process, following ISO standards protocols of ISO

• Test materials – selection, sample preparation,

checking homogeneity & stability

• Estimating assigned values of test materials

• Organising proficiency testing

• Evaluating submitted data and interpreting the results (appropriate

statistics & professional judgment)

• Establishing reference materials with reference values

External quality control system: PT programme

ASEANFOODS PT: food-based PT, using different food matrix as test materials: rice flour, soybean flour, milk powder, weaning food, cereal-soy, fish powder, snack: salted broad bean, whole wheat cracker

� different ways for sample preparation

How the QC system has been progressed? continued

9th IFDC, Norwich, UK 14-16 September 201112Grinder/milling machine

Food processor/meat mincer/Blenders

Instrument for test materials preparation

Ball mill

<125 mm

Changed from kitchenware to laboratory instrument: supported by IAEA

Ball mill-IAEAIAEA

Lyophiliser

From 1989 to 2008


Rotating mixer

Instrument for mixing test materials

V-shape mixer

Manual mixing

Sample preparation: instruments from AusAID

AusAID

PT sample is prepared in a room with controlled temperature and humidity.


Samples packed in can and laminated aluminum foil

Instrument for packing & containers

Vacuum sealing machine

Plastic sealing machine

PT sample is prepared in a room with controlled temperature and humidity.


1. Selection and preparation of candidate materials*

Analysis of required nutrients

Computation and statistical evaluation

Test material with assigned values of nutrients + documents

2. Testing for homogeneity and stability of representative nutrients*

Sample preparation sub-samples, packed in sealed containers

Rice flour, soybean flour, weaning food, fish powder, milk powder,….

1) Expert/outstanding laboratories[OCEANIAFOODS, Europe, USA, Canada]

2) PT participants

*Followed ISO Guide34,35, ISO 17043, ISO 5725, ISO 13528 3. Establishing assigned values of nutrients**

Proficiency testing programme

4. Proficiency Testing***

5. Evaluation of lab performance using robust z- score

Reference materials with reference values of nutrients

Values from good performance laboratories

Followed ISO 17043***

**Robust statistics and ISO 13528


1. Achievements on PT programme at ASEANFOODS Regional Centre (and at national level)

The nutrient parameters for evaluating performance included:

• Proximate composition

• Dietary fibre

• Minerals: Na, Ca, Fe, Zn

• Vitamins: vitamin A, vitamin B1, B2, folate

• Saturated fat, cholesterol, sugars

ASEANFOODS PT: food-based PT studies

What are our achievements?


Round Year Nutrients covered Level

I 1989 Main nutrients,,,, minerals Regional

II 1993-4 Main nutrients,,,, minerals Regional

III 1998-9 Mandatory nutrients for NL Regional

IV 1999-2000 Mandatory nutrients for NL National

V 2001 Proximate composition National

VI 2001-2 Total folate International

VII 2002-3 Mandatory nutrients for NL Regional

VIII 2005-6 Main nutrients, Fe, Zn, vit B1 International

IX 2009-10 Mandatory nutrients for NL National

X 2010-11 Mandatory nutrients for NL National

1. PT programme at ASEANFOODS Regional Centre

What are our achievements?


Main nutrients and 8 minerals

1989

1994

1998Mandatory nutrients for NL (Main nutrients, 3 mineralsCholesterol, Sat. FA, Sugars)

AS-FRM 1 Rice flourAS-FRM 2 Soybean flour

AS-FRM 3 Cereal-soy

AS-FRM 4 Fish flour-1

AS-FRM 5 Weaning foodAS-FRM 6 Fish flour-2

2003 AS-FRM 7 Milk powder

AS-FRM 8 Rice powder

FRM 17 Broad bean powder

Main nutrients and some minerals2005-6

2009 Mandatory nutrients for NL

2. Development of ASEAN food reference materials (AS-FRM)

Mandatory nutrients for NL

What are our achievements? continued


3. Conducting teaching, training, workshop

At national level: 1-3 times per year

Participants from

• Laboratory performance studies

• Accreditation Bodies, government and private

institutes and laboratories

At regional and international levels:

- APFAN training programme: QHSS, Australia

- AusAID programme: Indonesia, Thailand, Philippines

- FoodComp Courses: ASEAN, India, Australia____________________________________________________________________________________

*

~ 30 times, about 1500 participants

internal and external quality control system, test material preparation, proficiency testing, statistical evaluation,



4. Publications

4.1 PT Reports 9 x (8 English, 1 Thai)

4.2. Proceedings: ASEANFOODS, OCEANIAFOODS Conferences

4.3. Journals: 5 papers



5. Organising The 8th International Food Data Conference (8-IFDC) 1-3 October 2009, Thailand

Theme: “Quality Food Composition Data: key for health and Trade”

Website: http://www.inmu.mahidol.ac.th/8ifdc/


No. participants ~ 140 from 43 countries


Future activities of ASEANFOODS

2. Other activities of ASEANFOODS:

2.1 Revise, update and document National FCD of the ASEANFOODS members

2.2 Organise the 7th ASEANFOODS Workshop in 2013

2. 3 Develop the second version of the ASEAN FCD in 2013

2.4 Revise ASEAN Manual of Food Analysis

(http://www.inmu.mahidol.ac.th/aseanfoods/Activities.htm)

2.5 Harmonise and prepare guidelines or protocols for food composition data

generation and compilation system

2.6 Revise and update ASEANFOODS Website regularly

(http://www.inmu.mahidol.ac.th/aseanfoods.)

2.7 Collaborate other Regional Centres and INFOODS activities

1. Development of good quality Food analysis laboratories

1.1 Organising proficiency testing by ASEANFOODS Regional Centre and the member Countries

a. Analysis of problematic nutrients for nutrition labelling: dietary fiber, sugars, vitamin B1, B2

b. Analysis of iodine in iodised salt and in food samples1.2 Continue providing training and workshop on internal and external quality

control system (on request) at regional and national levels


Financial support:National agencies: INMU

• National Science and Technology Development (1993, 2005) • Thailand Research Fund (2009-2010)

International agencies: AusAID, FAO, INF, IAEA

Collaborators and contributors: expert laboratories, ASEANFOODS membersand all participants

Technical advisors:Dr. William Horwitz, Dr. Pieter Scheelings, David Mugford, Dan Tholen, Paul Armishaw, staff from IAEA and IRMM

Thank you for your attention

INMU-PTPWorking team

AOAC-TDRM award 2008

ReferenceReference Materials Achievement AwardMaterials Achievement Award

Documents

Achievements and future plan on development of good