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Technological Innovation for Health
Abdallah S Daar
McLaughlin-Rotman Centre for Global Health
UHN/University of Toronto
• Necessary ingredients
• Failures
• Success stories
• Empirical studies
• Innovative solutions
Necessary Ingredients
1. Operational access to good science2. Identification and prioritizing needs3. Confidence in developing ideas4. Supportive environment (policies, entrepreneurship,
ideology, culture, private sector)5. Tech transfer and IP systems6. Total skill sets available for tech development,
commercialization and marketing7. Provision of capital: proof of principle, valley of death,
venture capital8. Supportive health systems capable of internalizing tech
Failure : Hep B Vaccine
Presentation Title / DateUlmer, J.B. and Liu, M.A. 2002. Ethical Issues for vaccines and immunization. Nat Rev Immunol 2 291-296
• discovered- 1967
• 1st vaccine- 1969
• available- in U.S. 1982
Success: Cuba and Meningitis B Vaccine
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Success and Failure: A to Z
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Stagnant Technologies
1. Natural Products
Extraction of Artemisia Annua: Tanzania
Tanzed: an anti-HIV protein based compound in Tanzania
2. Diagnostics
Dip-stick Schistosomiasis: Ghana
Rapid HIV Diagnostic Kits: Kenya
3. Mosquito Repellants: Nigeria , Kenya
4. Pyrethrum-based Mosquito Nets: Rwanda
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Empirical Studies: Ghana, Tanzania and Rwanda
Key findings based on a 110 interviews
1. Lack of synergy and knowledge flows between various stakeholders
2. Inadequate financial incentives/resources for commercialization
3. Unexploited potential to commercialize innovative products
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Innovative Solutions
1. Held stakeholder workshops in Ghana, Tanzania and Rwanda with over 200 participants • Our preliminary findings were validated
and the concept of Convergence Innovation resonated with all stakeholders
2. Developed business plans and presented them to Science Ministers• Ministers appointed local steering
committees to implement Convergence Platforms
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What is Convergence Innovation?
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How might a convergence centre be funded?
“In particular the Bank should support the
development of national and regional centers
of excellence in the health sciences and in
Energy and environmental technologies. There
are significant potential benefits from
strengthening the linkages between life sciences
and the private sector. These centers would
facilitate and incubate innovation, supporting
entrepreneurship and developing technologies.”
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1. We identified very little venture capital invested into life sciences
2. IFC has announced a health venture fund for Africa
3. Plans to mobilize up to $1B, including an $350M equity vehicle with initial investments of $100M
4. Partnerships will be important to mitigate and tier risk and demonstrate that this market failure can be bridged
How Might Technologies Be Funded?
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Thank You
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Additional funding partners for the McLaughlin-Rotman Centre for Global Health can be found at www.mrcglobal.org
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