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Research Retreat Current Overview. Tom Hostetter Vice Chairman for Research. Some Outcomes of Last Retreat 2009. Agre Society solidified Annual Research Day Distribution of CTSC resources Meeting with SOM and UH leaders regarding research issues. Research Award Costs ( $ millions). - PowerPoint PPT Presentation
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Research RetreatCurrent Overview
Tom Hostetter
Vice Chairman for Research
Some Outcomes of Last Retreat 2009
• Agre Society solidified
• Annual Research Day
• Distribution of CTSC resources
• Meeting with SOM and UH leaders regarding research issues
Research Award Costs ( $ millions)
Year 07- 08 08- 09 09- 10 10- 11 11- 12
DOM 47.2 51.0 64.4 62.5 55.2
SCC 5.3 5.2 4.9 4.9 6.5
Research Cost 2011- 2012
Federal StateFoundatio
n Industry Total
CV Medicine 7,046,710 0 2,515,492 1,080,523 10,642,725
Clinical Pharm 446,135 0 0 0 446,135
Endocrinology 1,175,716 0 2,500 49,005 1,227,221
GI 3,635,636 0 0 238,013 3,873,649
Gen Med 313,600 0 0 0 313,600
Geriatrics 70,229 0 0 0 70,229
Heme/Onc 4,574,093 0 781,040 998,973 6,354,106
ID/HIV/Medicine 23,857,151 192,541 636,169 107,611 24,793,472
Nephrology/Hyp 4,837,604 0 0 70,302 4,907,906
Pulmonary/CC/Sleep 2,238,545 0 100,000 260,480 2,599,025
Rheumatology 0 0 0 0 0
Sources of Awards 2011- 2012($ millions)
Federal State Foundation Industry
48.2 .2 4.0 2.8
Selected Highlights 2012
• VAMC- Highly Funded Programs in Implementation, Quality and Education Research Basic and applied studies of antibiotic resistance GREC revitalized• CV- High impact papers in Science and Nature 6 new RO1s and a DARPA grant Mukesh Jain elected VP of ASCI• Endo- NIH trials ACCORDION,EDIC Studies in diabetic retinopathy• GI- NIH funded Network for study of Barrett’s PPG for IBD
Over 40 new or competing renewal grants, one half from NIH
Selected Highlights 2012
• Heme/Onc- Cancer Center renewed High impact papers in NEJM, PLOS Genetics, JBC, PNAS• ID- Progress in HIV and TB research Creation of ID and Immunology Institute Expansion of work in Uganda including CV Neuro, & Genetics• Renal/Htn- Leadership in NIH SPRINT and CRIC trials Ongoing participation in NIH Clinical Trials in Organ Transplantation 2 endowed faculty positions from Centers for Dialysis Care
Underrepresented Areas
• Topics
- Human/Population Genetics
- Outcome/Health Care Delivery - Comparative Effectiveness Research - Geriatrics
• Grant Types - K grants - for early career - P and U grants – for multiple investigators - Industry
Threats to Funding
•NIH budget has been declining in constant dollars about 10 years ( ARRA funds in 2009 and 2010 excepted)•Sequestration of 5- 10% of NIH budget will lead to about 2500 fewer new grants funded
FASEB
Responses To Funding Threats
• Industry support- now about 6 % of total
Responses To Funding Threats
• Industry support
• Philanthropy
Examples: Harrington Discovery Institute
Centers for Dialysis Care
Responses To Funding Threats
• Industry support
• Philanthropy
• Widen range of Federal Sources CTSC cores and pilot grants
AHRQ
DOD
PCORI
Patient Centered Outcomes Institute (PCORI)
• Part of the Affordable Care Act
• 2013 Budget $390 million
• PCORI approved 25 awards, totaling $40.7 million over three years, to fund patient-centered comparative clinical effectiveness research projects
PCORI’sResearch Budget Distribution
Responses To Funding Threats
• Industry support• Philanthropy• Widen range of Federal Sources CTSC cores and pilot grants AHRQ DOD PCORI
• Better grants to Traditional Federal Sources Multi PI / Team
Collaboration with other departments / institutions
Training
• Med Students Theses
• Residency short track
• Grad Students Tuitions
• F, T and K NIH Grants
Medical Student Theses
• Students are required to write a thesis.• They have 4 months of committed time and an
optional summer block after 1st year.• About 8% work in the DOM for their theses• To let students know of your research, update
your info on the ePortfolio site. https://casemed.case.edu/ePortfolioFaculty08/
• Also send email to Todd Fennimore, Director of the Office of Medical Student Research, txf80@case.edu.
Arrive at CWRU
School of Medicine
Year 1 Year 2 Year 3 Year 4
Begin investigating
areas of research interest
Contact potential mentors for the
summer with the idea of a project
that leads into the research block in
year 3.
Decide on a mentor for
the summer and submit
IRB applications & funding
applications.
Medical Student Research Timeline
SUMMER RESEARCH
Schedule Yr 3 including the
research block
Submit the research proposal
and submit IRB
application
4 mo.
Research progress
reports due at 1 and 2 month
points
Research summary due
the Friday after the end of the research block
Work on M.D. thesis
M.D. thesis due by
January 15th of the 4th
year
Lepow Medical Student
Research Day
Lepow Medical Student
Research Day
RESEARCH BLOCK
Lepow Medical Student
Research Day
29%
48%
The value of a research continuum including the summer between years 1 & 2 as well as the research block in year 3.
Courtesy of Jim Bruzik
Percent of Published Student Research
Training
• Med Students Theses
• Residency Short Track
• Grad Students Tuitions
• F, T and K NIH Grants
Graduate Student Support by DOM
•Selected PhD students enrolled in SOM with a DOM PI
•DOM will pay their tuition
•PI must pay their stipend from grant, etc and division guarantee support for the term of the student’s course.
•About 20 students are being supported
Break Outs• Breakout #1: Evolving NIH/Federal Funding Landscape Leaders: Richard Walsh, MD & Fabio Cominelli, MD
• Breakout #2: Mentoring and Career Development Leaders: Mukesh Jain, MD & Aaron Proweller, MD
• Breakout #3: Team Science and Multidisciplinary Research Leaders: Amitabh Chak, MD, Stanton Gerson, MD & Robert Salata, MD
• Breakout #4: Enhancing Industry-sponsored Research Opportunities Leaders: Neal Meropol, MD, & Marco Costa, MD, PhD
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