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Project No. Title Supervisor(s) Student Name PC-1 The synthesis and characterisation of
artemisinin conjugates: an approach to overcoming artemisinin resistance in Plasmodium falciparum
Main-Sup: Prof. Christina Chai Collaborator: Dr. Laurent Renia Executive Director and Principal Investigator, SIgN, A*STAR
ZHANG RUIRUI
PC-2 Exploring synthetic routes to dopamine and L-DOPA adducts and assessing their cytotoxicities in neuronal cell lines
Main-Sup: Prof. Christina Chai TAN YAO XIANG
PC-3 Evaluating the potential of N-substituted indoles for development as inhibitors of the Chikungunya virus
Main-Sup: Prof. Christina Chai Collaborator: Dr. Lisa Ng Senior Principal Investigator, SIgN, A*STAR
DONAVAN MARCUS NEO
PC-4 Structure-based virtual screening for FTO inhibitors
Main-Sup: Asst. Prof. Esther Woon TANG EE FHONG
PC-5 Investigating analogues of 2-oxoglutarate as possible probes in the functional and structural studies of FTO
Main-Sup: Asst. Prof. Esther Woon XIE YIMING
PC-6 Investigation of indirubin analogues as modulators of p-glycoprotein (ABCB1)
Main-Sup: Dr. Sim Hong May Collaborator: Dr. Wee Xi Kai Lecturer, Singapore Polytechnic/School of Chemical & Life Sciences
NGUYEN NGOC TUAN
PC-7 Investigation of indirubin analogues as anti-proliferative agents
Main-Sup: Dr. Sim Hong May Co-Sup: A/Prof. Ho Han Kiat Collaborator: Dr. Wee Xi Kai Lecturer, Singapore Polytechnic/School of Chemical & Life Sciences
NUR ‘ALIAH BINTE DAFIR
PC-8 Synthesis and structure-activity relationships (SAR) of novel anti-cancer indole derivatives
Main-Sup: A/Prof. Brian W Dymock TAN RUI ZHE JOEL
PC-9 Synthesis and biological evaluation of novel dual acting pro-drugs with anti-cancer and chemoprotective properties
Main-Sup: A/Prof. Brian W Dymock PANG XIN XIAN
PC-10 Synthesis of ninhydrin analogues as inhibitors of the SALL4-NuRD complex
Main-Sup: A/Prof. Brian W Dymock DAVID LOW YEE CHUEN
PC-11 Investigating the antimicrobial activity and cytotoxicity of Nε-lysylated analogues of melittin
Main-Sup: A/Prof. Chan Lai Wah Co-Sup: Dr. R. Lakshminarayanan Deputy Head; Principal Research Scientist Singapore Eye Research Institute
XIE QINGXIAO
PC-12 Synthesis and characterization of novel multi-targeting chemical entities for the treatment of Parkinson’s disease
Main-Sup: A/Prof. Giorgia Pastorin TAN SI YUN
PC-16 Cardiovascular drug response-related gene expression profiling in patients with cardiovascular disease
Main-Sup: Prof. Chen Yu Zong CHANG HEMIN
PC-17 Expression analysis of drug response-related genes in type 2 diabetes patients
Main-Sup: Prof. Chen Yu Zong PRATIBHA NAIR D/O PRADEEP RAJ
PC-18 A study of the potential anticoagulant effects and active components of a medicinal plant
Main-Sup: A/Prof. Koh Hwee Ling Assisted by: Ms. Kamonlawan Chomchopbun
QU XIAOJIE
PC-19 Computer-aided design of enzyme inhibitors for the antiproliferation of Mycobacterial tuberculosis
Main-Sup: A/Prof. Chui Wai Keung Assisted by: Mr. Yang Xuan
CHUA JIA JING
PHARMACEUTICAL CHEMISTRY (PC)
PHARMACEUTICAL BIOLOGY AND PHARMACOKINETICS (PK) Project No Title Supervisor(s) Student Name PK-1 Global metabonomics of infant stool in
childhood eczema Main-Sup: A/Prof. Eric Chan Chun Yong Collaborator: Prof. Lee Bee Wah Professor, YLLSOM, Dept of Paediatrics
WOON JIA YUN
PK-2 Plasma nutrikinetics of polyphenolic metabolites in healthy volunteers following consumption of two doses of mixed spices in the PolySPice (PSP) study
Main-Sup: A/Prof. Eric Chan Chun Yong Collaborators: Dr. Sumanto Haldar Senior Research Fellow, Clinical Nutrition Research Centre (CNRC), Singapore Institute for Clinical Sciences (SICS), A*STAR Prof. Christiani Jeyakumar Henry Director, Clinical Nutrition Research Centre (CNRC), Institute for Clinical Sciences (SICS), A*STAR
TAN JUN JIE
PK-3 Inhibition of soluble epoxide hydrolase by amiodarone, dronedarone and their active metabolites
Main-Sup: A/Prof. Eric Chan Chun Yong TRAM DAI THIEN NHAN
PK-4 Production of soluble dectin-1 and dectin-1 Fc
Main-Sup: A/Prof. Eric Chan Chun Yong Co-Sup: Dr. Ng Say Kong
LIM SHI ZONG NIGEL
PK-6 Structural and inhibition analysis of the human AlkB family of demethylases
Main-Sup: Asst. Prof. Esther Woon FRANSISCA PRASETYA
PK-7 Biological evaluation of the anti-inflammatory and cytoprotective properties of ribisin compounds on neuronal cells
Main-Sup: A/Prof. Chew Eng Hui HU JIAYI
PK-8 Biological characterization of the antiproliferative properties of dual targeting compounds containing dihydrotriazine and chalcone pharmacophores
Main-Sup: A/Prof. Chew Eng Hui
CHONG SWEE YUE ADRINA
PK-9 Investigating the basis for differences in efflux efficiencies of PDR5 and PDR15
Main-Sup: Dr. Sim Hong May Collaborator: Dr. Prakash Arumugam Principal Investigator, Bioinformatics Institute, A*STAR
SIN MEI FANG
PK-10 In vitro pharmacodynamics of Fosfomycin against Carbapenem-resistant Enterobacteriaceae
Main-Sup: A/Prof. Andrea Kwa Lay Hoon Co-Sups: Lim Tze Peng, Jocelyn Teo
GOH WEI LING AUDREY
PK-11 Quantification of 3′-hydroxypterostilbene in rat plasma: Application to pre-clinical pharmacokinetic study
Main-Sup: Asst. Prof. Lin Haishu LEE WEN SIN
PK-12 Quantification of desoxyrhapontigenin (4′-methoxyresveratrol) in rat plasma: Application to pre-clinical pharmacokinetic study
Main-Sup: Asst. Prof. Lin Haishu TAN LI CHENG AMANDA
PC-20 Modification of 4,6-diamino-1,3,5-triazine scaffold for potential inhibition of Mycobacterium tuberculosis dihydrofolate reductase
Main-Sup: A/Prof. Chui Wai Keung Assisted by: Mr. Yang Xuan
WANG YANZHEN
PC-21 1-Arylalkyl analogs of Mannich bases of indoles as potential antimycobacterial agents
Main-Sup: A/Prof. Go Mei Lin WONG SIAN LIN
PC-22 Cinnamoyl derivatives of indoles as potential antimycobacterial agents
Main-Sup: A/Prof. Go Mei Lin NGUYEN HUU THANH DUY
PC-23 Evaluation of 4-fluoro-1H-indole and 6-methoxy-1H-indole derivatives as potentially novel tuberculosis agents
Main-Sup: A/Prof. Go Mei Lin LOW YI HAO
PK-13 Anti-tumor effects of KPT-330 (Selinexor®) as monotherapy and in combination with Gemcitabine in nasopharygneal carcinoma.
Main-Sup: Dr. Ong Pei Shi Co-Sup: Dr. Wang Lingzhi Senior Scientist, Cancer Science Institute of Singapore, NUS Collaborator: Prof. Goh Boon Cher Principal Investigator/ Head and Senior Consultant, Cancer Science Institute of Singapore, NUS/ Department of Hematology, NUH
LIM DAH WEI
PK-14 Anticancer mechanisms of single agent aurora-A kinase inhibitor (MLN8237) and its combination with cisplatin against NPC cells
Main-Sup: Dr. Ong Pei Shi Co-Sups: A/Prof. Gautam Sethi Department of Pharmacology Dr. Wang Lingzhi, Senior Scientist, Cancer Science Institute of Singapore
VU TAI ANH
PK-15 Induction of natural killer cell killing by medicinal plant
Main-Sup: A/Prof. Koh Hwee Ling Assisted by: Dr. Neo Soek Ying
TAN WEI XUN
PK-16 Inhibition of sulfotransferase 2A1-catalyzed LCA sulfation by anti-androgens
Main-Sup: Asst. Prof. Lau Aik Jiang NG WAN XIN YVONNE
PK-17 Substrate selectivity of human aldehyde oxidase-1
Main-Sup: Asst. Prof. Lau Aik Jiang XIE JIARONG
PK-18 Inhibition of human aldehyde oxidase-1 by epidermal growth factor receptor tyrosine kinase inhibitors
Main-Sup: Asst Prof. Lau Aik Jiang TAN WEE KIAT
PK-21 Generation of specific cell lines for loss of function analysis of critical regulators of apoptosis signalling using the CRISPR-Cas9 System
Main-Sup: A/Prof. Victor Yu Assisted by: Dr. Tan Chong Teik
LIM CHEONG CHENG
PK-22 Tacrolimus pharmacokinetics before and after conversion from twice-daily Prograf to once-daily Advagraf, with or without Diltiazem, in Asian adult kidney transplant recipients
Main-Sup: Dr. Yau Wai Ping Collaborator: Prof. Anantharaman Vathsala Head, Division of Nephrology, NUHS
LOH WEI TING CHARLENE
PK-23 Evaluation of genetic variants in diabetes susceptibility genes and disposition-related genes as potential risk factors for new-onset diabetes after transplantation in Asian kidney transplant recipients in Singapore
Main-Sup: Dr. Yau Wai Ping Collaborator: Prof. Anantharaman Vathsala Head, Division of Nephrology, NUHS
YEO MIN XIU SHERLIN
PK-24 Combination of silibinin and TiO2 nanoparticles for the treatment of liver fibrosis
Main-Sup: A/Prof. Ho Han Kiat NG WEN WEI
PK-25 Investigating the role of FGFR in liver fibrosis using gene silencing approach
Main-Sup: A/Prof. Ho Han Kiat TEO WEN YA
PK-26 Evaluating the association between vancomycin trough concentration and 24-Hour area under the concentration-time curve in Asian neonates
Main-Sup: Prof. Ho Chi Lui, Paul Co-Sup: Lim Chuan Poh Pharmacist, SGH Pharmacy Collaborators: Kong Sing Teang Pharmacist, SGH Pharmacy Chen Qi Senior Clinical Pharmacist, KKH Pharmacy
TSENG SHENG HSUAN
PK-28 Validation of a rapid and sensitive LC- MS/MS method for the determination of MELK inhibitor OTSSP167 and its application in preclinical pharmacokinetic study
Main-Sup: Prof. Ho Chi Lui, Paul Co-Sup: Dr. Wang Lingzhi Senior Scientist, Cancer Science Institute of Singapore, NUS
EE QIN YING MITCHELL
PK-29 Comparison between the effects of cancer and healthy plasma exosomes in inducing epithelial-meschenchymal transition (EMT) in H460 cells
Main-Sup: Prof. Ho Chi Lui, Paul Co-Sup: Dr. Wang Lingzhi Senior Scientist, Cancer Science Institute of Singapore, NUS
LOH YEOW HOOI EDWARD
PK-30 Verification of the molecular mechanism of carboplatin and LBH589 against NSCLC cells through perturbation of MAPK/ERK signalling pathways
Main-Sup: Prof. Ho Chi Lui, Paul Co-Sup: Dr. Wang Lingzhi Senior Scientist, Cancer Science Institute of Singapore, NUS Collaborator: Prof. Goh Boon Cher Cancer Science Institute of Singapore, NUS
ANG SOON XIN
PK-31 Mitochondrial DNA content in peripheral blood as a biomarker for Cancer Related Fatigue in Early-Stage Breast Cancer Patients: A Prospective Cohort Study
Main-Sup: A/Prof. Alexandre Chan Co-Sup: A/Prof. Ho Han Kiat Collaborator: Dr. Jung-woo Chae Research Fellow, NUS Pharmacy
CHUA PEH SIANG
PK-32 Evaluation of BDNF genetic polymorphism and chemotherapy-associated cognitive impairment in patients with early-stage breast cancer
Main-Sup: A/Prof. Alexandre Chan Co-Sup: A/Prof. Ho Han Kiat Collaborator: Dr. Jung-woo Chae Research Fellow, NUS Pharmacy
CLIVIA YAP YAO HUA
PK-33 Comparison of hair follicle chemotherapeutics concentrations in breast cancer patients with or without cryotherapy for preventing alopecia during chemotherapy
Main-Sup: A/Prof. Alexandre Chan Co-Sup: A/Prof. Ho Han Kiat Collaborator: Dr. Jung-woo Chae Research Fellow, NUS Pharmacy
WU XINYI
PK-34 Autophagy as a molecular mechanism in mediating toxicity of nanomaterials
Main-Sup: A/Prof. Gigi Chiu LOW FOO ENG
PK-35 Identification of polymer based para-phenylenediamine (PPD) derivative as alternative chemical for hair dye
Main-Sup: A/Prof. Giorgia Pastorin AZRITANIA ISKANDER
PK-36 Biological evaluation of sulfonylamide-substituted phenanthrenediones as inhibitors of Wnt signaling pathway
Main-Sup: A/Prof. Rachel Ee CHUA YONG QUAN NEVILLE
PK-37 Investigation of the chemical interactions between short chain fatty acids and human histone deactylases
Main-Sup: A/Prof. Eric Chan Chun Yong Collaborator: Dr. Fan Hao Principal Investigator, Bioinformatics Institute A*STAR Prof. Lee Bee Wah YLLSOM, Dept of Paediatrics
HO ROU HUI
Project No. Title Supervisor(s) Student Name PT-3 An analysis of GMP standards and
regulatory framework in major pharmaceutical exporting countries, the challenges impacting on the quality and safety of finished pharmaceutical products, and future directions
Main-Sup: A/Prof. Chan Lai Wah Co-Sup: Adjunct A/Prof. Sia Chong Hock Director (Quality Assurance Office) Health Sciences Authority (Health Products Regulation Group)
LOO SHANG JUN
PT-4 Investigation of freeze-drying conditions on the properties of freeze-dried mannitol-HPMC cushioning excipients for MUPS tablets
Main-Sup: A/Prof. Chan Lai Wah Assisted by: Carin Siow (postgraduate)
HE RONGHUI
PT-5 Understanding paraffin waxes and their potential application in the development of drug delivery systems by spray congealing
Main-Sup: A/Prof. Chan Lai Wah Assisted by: Ouyang Hongyi (postgraduate)
AUDREY ZHENG YI
DRUG DELIVERY AND PHARMACEUTICAL TECHNOLOGY (PT)
PT-6 Optimization of 3D printable resin for the development of a personalised swellable microneedle array in the treatment of alopecia
Main-Sup: Dr. Kang Lifeng MUHAMMAD HAFIZ B AMIR
PT-7 Optimizing microneedle geometry on varying curvatures for transdermal delivery of small peptides in treatment of facial wrinkles
Main-Sup: Dr. Kang Lifeng TIEW WEN JUN
PT-8 Fabrication of slow-dissolvable microneedle for transdermal immunotherapy
Main-Sup: Dr. Kang Lifeng DENNIS LIM WEI MIN
PT-9 Evaluating mechanical properties of hydrogels on dermal papilla cell gene expressions
Main-Sup: Dr. Kang Lifeng CHOU KEAT ONN
PT-10 Design and development of nano-vesicles for delivery of small molecules and small peptides for skin treatment.
Main-Sup: Dr. Kang Lifeng CHA SAERA
PT-11 3D Printed multichannel devices for skin permeation studies
Main-Sup: Dr. Kang Lifeng YEO SHIH HUI
PT-12 Influence of lubrication methods during dry granulation and tableting on tablet compaction
Main-Sup: Dr. Celine Liew Assisted by: Parthiban Anbalagan
WONG LI TING JOANNE
PT-13 Coat variability in multi-particulate drug delivery systems: A comparative study between mini-tablets and pellets
Main-Sup: Dr. Celine Liew Assisted by: Goh Hui Ping
CHAN HAN KUAN
PT-14 Evaluation of flow and electrostatic properties of pharmaceutical powders
Main-Sup: Dr. Celine Liew Assisted by: Goh Hui Ping
CHAN YU SEN ALVIN
PT-15 Influence of tableting punch face design on powder adhesion during tablet compaction
Main-Sup: A/Prof. Paul Heng Co-Sup: Dr. Celine Liew Assisted by: Parthiban Anbalagan
VIVIAN CHIN HUI MIN
PT-16 Influence of paraffin wax on physical properties of paracetamol compacts
Main-Sup: A/Prof. Paul Heng Co-Sup: Dr. Celine Liew Assisted by: Joanne Teh / Lesley Ooi
ELAINE CHAN YONG SHI
PT-17 Impact of lubricants on powder flowability and compact tensile strength
Main-Sup: A/Prof. Paul Heng Co-Sup: Dr. Celine Liew Assisted by: Justin Tay / Lesley Ooi
CHRISTINA KANG YONG XIN
PT-18 Developing cosmetic facial masks using 3D-printing and pharmaceutical approach
Main-Sup: Prof. Ho Chi Lui, Paul Co-Sup: A/Prof. Yen Ching Chuan, Head, School of Design and Environment Collaborator: Dr. Ma Sha Research Engineer, Department of Mechanical Engineering
CALLY CHEW YIN FANG
PT-19 Using stereolithographic (SLA) and food 3D food printers to fabricate customized paediatric dosage forms
Main-Sup: Prof. Ho Chi Lui, Paul Co-Sup: Prof. Ellen Yi-Luen Do, Interactive & Digital Media Institute, NUS Collaborator: Dr. Yan Liangkun Research Engineer, Interactive & Digital Media Institute, NUS
TAN ENG LEONG
PT-20 Stability of anidulafungin in pharmaceutical solutions
Main-Sup: Prof. Ho Chi Lui, Paul Collaborators: Yeoh Siang Fei Lim Yin Shan Senior Principal Pharmacist, NUHS
YAP CHIEN
PT-21 Lipid-dendrimer hybrid nanosystems: An in vitro study on drug accumulation and cellular interaction
Main-Sup: A/Prof. Gigi Chiu OH WEI JUN
PT-22 Lipid-dendrimer hybrid nanosystem as potential anti-microbial agent
Main-Sup: A/Prof. Gigi Chiu CHUA XING TING AILEEN
PT-23 Addressing the needs of an aging population
Main-Sup: A/Prof. Giorgia Pastorin FAITH HONG SHITING
A novel formulation approach to deliver natural products for arthritis
PT-24 The effect of secondary structures on antimicrobial, anti-biofilm and anti-inflammatory properties of peptide amphiphiles
Main-Sup: A/Prof. Rachel Ee GOH CHENG EE
PT-25 Development and characterization of DNA hydrogels as antimicrobial peptide delivery platforms
Main-Sup: A/Prof. Rachel Ee TAY KAI LIN HILDA
PT-26 In vivo efficacy of phenylboronic acid-functionalized polycarbonate hydrogels for polymyxin B delivery
Main-Sup: A/Prof. Rachel Ee LOW MEI WEN
Project No. Title Supervisor(s) Student Name PP-1 A qualitative study exploring the
interpretation and use of the EQ-VAS amongst Chinese and Malay Singaporeans
Main-Sup: Asst Prof. Wee Hwee Lin Co-Sup: A/Prof. Luo Nan Associate Professor, Saw Swee Hock School of Public Health
JONATHAN KOH ENG TIONG
PP-3 Exploring the content validity of the EQ-5D health descriptive system: a qualitative study of ethnic Chinese and Malays in Singapore
Main-Sup: Asst Prof. Wee Hwee Lin Co-Sup: A/Prof. Luo Nan Associate Professor, Saw Swee Hock School of Public Health
TIMOTHY BEN CHANG KAI SHENG
PP-5 Are preference-based quality of life instruments originated from Western cultures suitable for use in Asia? A systematic review
Main-Sup: Asst Prof. Wee Hwee Lin Co-Sup: A/Prof. Luo Nan Associate Professor, Saw Swee Hock School of Public Health
ONG JIA MIN JOY
PP-6 Use of Linezolid for intra-abdominal enterococcal infections
Main-Sup: A/Prof. Andrea Kwa Lay Hoon Co-Sups: Loo Li Wen, Pharmacist, SGH, Pharmacy Teo Bao Wen, Pharmacist, SGH, Pharmacy
WONG TSEUNG JUN
PP-8 Efficacy and safety of high-dose versus standard-dose Polymyxin B in patients with Carbapenem-resistant gram-negative bacteria infections: A propensity-adjusted and propensity matched study
Main-Sup: A/Prof. Andrea Kwa Lay Hoon Co-Sup: Cai Yiying Pharmacist, SGH, Pharmacy Collaborator: Jocelyn Teo Specialist Pharmacist, SGH, Pharmacy
RAY TAN WEI JIE
PP-9 Clinical outcomes in healthcare-associated pneumonia (HCAP) patients treated with broad-spectrum versus narrow-spectrum antibiotics therapy: A single-centre study in Singapore
Main-Sup: A/Prof. Andrea Kwa Lay Hoon Co-Sup: Lee Hui Ling Winnie Principal Clinical Pharmacist, SGH, Pharmacy Collaborator: Narendran S/O Koomanan Pharmacist, SGH/Inpatient Pharmacy
NGUYEN PHI YEN
PP-10 Association of obesity with patient-reported outcomes in patients with Axial Spondyloarthritis: A cross-sectional study in an urban Asian population
Main-Sup: A/Prof. Chew Eng Hui Collaborators: Dr. Warren Fong Rheumatology and Immunology, SGH Mr. Kwan Yu Heng, Duke-NUS Prof. Julian Thumboo, Singhealth Prof. Truls Ostbye, Duke Durham
LEE YI XUAN
CLINICAL PHARMACY AND PHARMACY PRACTICE (PP)
PP-11 Factors associated with initiation of biologics in patients with Axial Spondyloarthritis in an urban Asian city: A PRESPOND study
Main-Sup: A/Prof. Chew Eng Hui Collaborators: Dr. Warren Fong Rheumatology and Immunology, SGH Mr. Kwan Yu Heng, Duke-NUS Prof. Julian Thumboo, Singhealth Prof. Truls Ostbye, Duke Durham
PNG WAN YU
PP-12 Association between access to health-promoting facilities and participation in cardiovascular disease risk screening among populations with low socioeconomic status in Singapore
Main-Sup: A/Prof. Chan Sui Yung Collaborators: Prof. T Østbye, Mr. Lim Ka Keat, Mr. Kwan Yu Heng, Duke-NUS Mr. Tay Hung Yong Singapore Heart Foundation Dr. Warren Fong, Singapore General Hospital Dr. Tan Chuen Seng Saw Swee Hock School of Public Health
CHARMAINE LIM
PP-13 Analysis of spontaneously reported cutaneous adverse drug reactions reports in Singapore from 2006 to 2015
Main-Sup: A/Prof. Chan Sui Yung Collaborators: Dr. Dorothy Toh Asst Group Director, Post-Market Cluster Health Sciences Authority Singapore Ms. Jalene Poh Director, Vigilance and Compliance Branch Health Sciences Authority Singapore Ms. Tham Mun Yee Regulatory Specialist, Adverse Event Management Unit, Health Sciences Authority Singapore, Health Products Regulation Group A/Prof. Chan Cheng Leng Group Director, Health Sciences Authority Singapore, Health Products Regulation Group Prof. Goh Chee Leok Senior Consultant, National Skin Centre Dr. Cheong Han Hui Department of Pharmacy, KK Women’s and Children’s Hospital
WONG SI XIAN
PP-14 Understanding the future of medication supply for rheumatology patients in Singapore
Main-Sup: A/Prof. Chan Sui Yung Collaborators: Prof. Julian Thumboo Singhealth Health Services Research Centre Mr. Kwan Yu Heng, Duke-NUS Mr. Lim Mun Moon, Director Pharmacy, Singapore General Hospital
HO WEI YANG, TIMOTHY
PP-15 Evaluation of reports of poor quality health products in Singapore and other countries from 2010 to 2016
Main-Sup: A/Prof. Chan Sui Yung Collaborators: Mr. Choong Chih Tzer Senior Regulatory Specialist Health Sciences Authority, Common Vigilance Unit, Health Products Regulation Group Ms. Ang Pei San Health Sciences Authority, Common Vigilance Unit, Health Products Regulation Group Designation: Regulatory Consultant Ms. Jalene Poh Health Sciences Authority, Vigilance and Compliance Branch Dr. Cheong Han Hui KK Women’s & Children’s Hospital, Department of Pharmacy
KOK LI TING
PP-16 Extemporaneous compounding and acceptability of orodispersible films as a paediatric dosage form
Main-Sup: A/Prof. Chan Sui Yung Collaborator: Dr. Cheong Han Hui Department of Pharmacy, KK Women’s and Children’s Hospital Ms. Foo Wen Chin (PhD student)
LIM XINYI, ALETHEA
PP-17 Attitudes and perceptions of complementary/alternative medicine in pre-dialysis chronic kidney disease Patients in a multi-ethnic society
Main-Sup: A/Prof. Priscilla How Co-Sup: Dr. Srinivas Subramanian Consultant, NUH Division of Nephrology
SOON WEI YONG BELINDA
PP-18 A study of the prevalence of dyslipidemia in local hemodialysis (HD) patients
Main-Sup: A/Prof. Priscilla How Co-Sup: Dr. Hersharan Sran Consultant, NUH Division of Nephrology
SOPHIA HENRY GOENAWAN
PP-19 Association of influenza and pneumococcal vaccination with hospitalization in dialysis patients
Main-Sup: A/Prof. Priscilla How Co-Sup: Dr. Hersharan Sran Consultant, NUH Division of Nephrology
KOH YIN WEI
PP-20 Assessing the medication and healthcare utilisation of elderly patients with inflammatory bowel disease in Singapore
Main-Sup: Dr. Ong Pei Shi Collaborator: Mr. Lim Teong Guan Senior Principal Pharmacist, SGH/Pharmacy Collaborators: Ong Wan Chee Senior Clinical Pharmacist, SGH/Pharmacy Chuah Sai Wei Pharmacist, SGH/Pharmacy
SOO ZHENG HAO
PP-21 Appropriateness of medication prescribing for hospitalized elderly cardiovascular patients in National University Hospital using the STOPP criteria
Main-Sup: Dr. Ong Pei Shi Collaborators: Ms. Deborah Chia Miao Hui Senior Pharmacist, NUH Ms. Wan Mei Qi Senior Pharmacist, NUH
CHIA WEI CHUN LESLIE
PP-24 Development and validation of DxD-Info: a tool for assessing the completeness of Drug-Drug interaction-related information in Drug information references
Main-Sup: Dr. Chng Hui Ting LOW KAI XIN
PP-25 Drug-drug interaction-related information in package inserts: how does it compare to other references
Main-Sup: Dr. Chng Hui Ting LOH DE-HOU JOSHUA
PP-26 The completeness of drug-drug interaction-related information of newly approved Drugs: A comparison among different references
Main-Sup: Dr. Chng Hui Ting CHUA ZHIJUN KENNETH
PP-27 Usage of herbal medicine in older adults in Singapore
Main-Sup: A/Prof. Koh Hwee Ling Co-Sup: A/Prof. Tan Chay Hoon
LIM YU TING, PRISCILLA
PP-28 Long term clinical and cost outcomes of pharmacist-managed risk factor management clinics in Singapore: A retrospective cohort study
Main-Sup: A/Prof. Joyce Lee Co-Sup: Ms. Kng Kwee Keng Principal Pharmacist (Clinical), TTSH/Pharmacy Collaborator: A/Prof. Alexandre Chan Associate Professor, NUS, Dept of Pharmacy
TAN SHE HUI
PP-29 The development of retail pharmacist-managed diabetes service in the community
Main-Sup: A/Prof. Joyce Lee Co-Sup: A/Prof. Alexandre Chan Collaborator: Ms. Tan Poh Leng Senior Pharmacist, Pharmacy Department, Watson’s Personal Care Stores Pte Ltd, Singapore Assisted by: Ms. Lim Sze Mian (PhD)
TAN WEI MIN
PP-30 Age bias in clinical trials of type 2 diabetes mellitus
Main-Sup: A/Prof. Grant Sklar LIM WEN XI JOYCE
PP-31 Is meldonium a performance-enhancing drug? A systematic review of the literature
Main-Sup: A/Prof. Grant Sklar MARIE CHEN LI WEN
PP-32 Use of complementary and alternative medicine (CAM) among adult patients with epilepsy in Singapore
Main-Sup: A/Prof. Grant Sklar Co-Sup: Dr. Wong Pei Shieen Principal Pharmacist (Clinical), Singapore General Hospital
CHEN QIANNI
PP-33
Safety and efficacy of aminoglycosides for the treatment of urinary tract infections (UTI) due to multi-drug resistant Escherichia coli and Klebsiella pneumoniae in the elderly population
Main-Sup: A/Prof. Christine Teng Co-Sup: Dr. Michelle Tan Senior Pharmacist, TTSH Assisted by: Aysu Selcuk (PhD)
GOH YI LING ELIZABETH
PP-34 Safety and efficacy of carbapenems for the treatment of urinary tract infection (UTI) due to multi-Drug resistant Escherichia coli or Klebsiella pneumoniae in the elderly population
Main-Sup: A/Prof. Christine Teng Co-Sup: Dr. Michelle Tan Senior Pharmacist, TTSH Assisted by: Aysu Selcuk (PhD)
TAN YU HENG
PP-35 Obtaining the best patient’s medication list: beyond electronic reconciliation
Main-Sup: A/Prof. Christine Teng Co-Sup: Lim Wan Peng Principal Clinical Pharmacist, TTSH/ Pharmacy
HUANG SHULEI
PP-36 Private chain community pharmacist’s knowledge, attitude and practice in performing medication reconciliation and review in Singapore
Main-Sup: A/Prof. Christine Teng Collaborator: Anson Lim Zong Neng Senior Pharmacist Pharmacy Department, Watson’s Personal Care Stores Pte Ltd, Singapore Assisted by: Cheong Yee Yin Pre-registration Pharmacist, Pharmacy Department, Watson’s Personal Care Stores Pte Ltd, Singapore
SEAH XUAN SHI SHERYL
PP-37 Pharmacists interventions of after-hours inpatient medication chart review: a 1-year service evaluation
Main-Sup: A/Prof. Christine Teng Co-Sup: Muhammed Taufiq Collaborator: Goh Lay Hong Principal Pharmacist, TTSH/Pharmacy
ONG KEN KIT BENNETT
PP-38 Impact of round the clock inpatient medication chart review on medication errors and “near-misses”
Main-Sup: A/Prof. Christine Teng Co-Sup: Lim Wan Peng Collaborator: Ng Tat Ming Principal Pharmacist, TTSH/Pharmacy
TEO CHONG JUNN
PP-39 Validation of a DRP classification system for intermediate and long term care setting in Singapore
Main-Sup: Dr. Yap Kai Zhen Co-Sup: Chung Wing Lam Principal Clinical Pharmacist, Pharmacy Department, Watson’s Personal Care Stores Pte Ltd, Singapore Collaborators: Kng Li Lin, Grace, Pharmacist, PSS ILTC Pharmacists Workgroup, PSS, Singapore Yeo Quan Qi, Pharmacist, PSS ILTC Pharmacists Workgroup, PSS, Singapore
LIM XIN YAN
PP-41 A process evaluation of the community pharmacist-led allergic rhinitis management (C-PhARM) service in Singapore
Main-Sup: Dr. Yap Kai Zhen Co-Sup: Joy Chong Principal Clinical Pharmacist, Pharmacy department, Watson’s Personal Care Stores Pte Ltd, Singapore Collaborators: Colin Tang, Pharmacist, Watson’s Personal Care Stores Pte Ltd, Singapore Helena Hor, Pharmacist, Watson’s Personal Care Stores Pte Ltd, Singapore
JOANNE YAP SHI YING
PP-42 Expectations and barriers of patient counselling in the community retail pharmacy settings in Singapore
Main-Sup: Dr. Yap Kai Zhen POH KAR MEN
PP-43 Development of a health supplements database and determining its usefulness to pharmacists in the community setting
Main-Sup: Dr. Kevin Yap Collaborator: Chan Wei, Max Pharmacist, Watson’s Personal Care Stores Pte Ltd
CHO JIE YI
PP-44 Evaluating the use of a serious game in pharmacy practice skills training
Main-Sup: Dr. Kevin Yap Co-Sup: Dr. Yap Kai Zhen
SHAWN IGNATIUS TAN BOON HENG
PP-45 Design and development of a mobile game to educate players on herbal medicines
Main-Sup: Dr. Kevin Yap Co-Sup: Dr. Yap Kai Zhen
RYAN EE WEI XUAN
PP-46 Development of a mobile app for adverse event reporting
Main-Sup: Dr. Kevin Yap LAM THI KHANH NGOC
PP-47 Development of a traditional Chinese medicines mobile app for chronic disease management
Main-Sup: Dr. Kevin Yap VIVIAN TAN
PP-48 Eczema information in the news media – Myths or facts
Main-Sup: Dr. Yau Wai Ping Co-Sups: Ms. Tan Mui Ling Dr. Goh Cheong Hian Health Sciences Authority
CHUA SEOW KOON
PP-49 Effects of central nervous system drugs on post-stroke motor function, cognition, disability and quality of life: A systematic review and meta-analysis of randomized controlled trials
Main-Sup: Dr. Yau Wai Ping Assisted by: Mr. Yeo See Hwee (Graduate Student)
LIM ZHENG JIE IAN
PP-50 Systematic Review on the performance of common genetic variants in breast cancer risk prediction models
Main-Sup: Asst Prof. Wee Hwee Lin LEE SHI XUN
PP-51 Cost-effectiveness of risk-stratified breast cancer screening: A modeling approach
Main-Sup: Asst Prof. Wee Hwee Lin KE YU
PP-52 P2Y12 inhibitors in acute coronary syndrome (PACS)
Main-Sup: A/Prof. Ho Han Kiat Co-Sup: Doreen Tan Collaborator: Kim Ji Heon Associate Consultant & Pharmacist, KTPH/Pharm
LEONG WEI QI
PP-53 Incidence of thromboembolic and bleeding events in patients newly diagnosed with non-Valvular atrial fibrillation: A multicentred retrospective cohort study
Main-Sup: A/Prof. Ho Han Kiat Co-Sup: Dr. Wee Xue Ting Senior pharmacist, Khoo Teck Puat Hospital, Pharmacy
HO LIH MAAN
PP-54 Psychometric properties and measurement equivalence of the Chinese and English version of the multidimensional fatigue symptom inventory-short form (MFSI-SF) in Asian cancer patients
Main-Sup: A/Prof. Alexandre Chan Collaborator: Xiao Jun (Nick) Wang (Graduate Student)
LEW SOOK FUI CLAIRE
PP-55 Psychosocial and symptom burden in adolescents and young adults patients diagnosed with cancer in Singapore
Main-Sup: A/Prof. Alexandre Chan CHUA XING RONG ANNABEL
PP-56 Minimal clinically important difference of the multidimensional fatigue symptom inventory-short form in Asian breast cancer and lymphoma patients
Main-Sup: A/Prof. Alexandre Chan Collaborator: Wang Xiaojun (Graduate Student)
YO ERI TIFFANY
PP-57 Healthcare providers’ perception on cancer survivorship delivery: A qualitative study
Main-Sup: A/Prof. Alexandre Chan NGAI GUO HUI
PP-58 Validation of a vancomycin dosing aid for Chronic kidney disease patients
Main-Sup: A/Prof. Alexandre Chan Co-Sup: Lee Siok Ying Assisted by: Sreemanee Dorajoo (Graduate Student)
CHRYSTAL LEANDR.A WINATA
PP-59 Impact of chemotherapy-induced peripheral neuropathy on health-related quality of life in Asian cancer patients receiving neurotoxic agents: A prospective study
Main-Sup: A/Prof. Alexandre Chan Co-Sup: Prof. Violeta Lopez Assisted by: Mr. Terence Ng (Graduate Student)
EMILY PANG QIAN LING
PP-60 Management of hepatitis B core antibody (anti-HBc) positive lymphoma patients: A retrospective study
Main-Sup: A/Prof. Alexandre Chan Collaborator: Mr. Md Ihtimam Hossain Bhuiyan, Pharmacist, Singapore General Hospital
DENISE YEO JIA QI
PP-61 A comparative study on the adverse drug effects of methotrexate therapy in atopic dermatitis and psoriasis
Main-Sup: Asst. Prof. Wong Li Lian Co-Sup: Mr. Benny Kaihui Li Manager (Pharmacy Quality & Safety), National Skin Centre Collaborator: Dr. Yew Yik Weng Consultant Dermatologist, National Skin Centre Adj A/Prof. Chong Wei Sheng, Senior Consultant Dermatologist, National Skin Care
NICHOLAS ONG DENG YUAN
PP-62 Public perception on self-medication and self-care in Singapore
Main-Sup: Asst. Prof. Wong Li Lian JOELANCE NG
PP-63 Retrospective review of the clinical efficacy of urokinase instillation for the management of occluded haemodialysis catheters
Main-Sup: Asst. Prof. Wong Li lian Co-Sup: Dr. Chuang Shen Hui Clinical Pharmacist, TTSH/Pharmacy
RACHEL CHOO HUI ZHEN
PP-64 Retrospective review of intra-dialytic administration of high dose Ceftazidime in haemodialysis patients
Main-Sup: Asst. Prof. Wong Li lian Co-Sup: Dr. Chuang Shen Hui Clinical Pharmacist, TTSH/Pharmacy
SHAUNA HUANG XIAORONG
PP-65 A study of medication use among cancer patients in hospice settings
Main-Sup: Asst. Prof. Lita Chew Collaborators: A/Prof. Gerald Koh, Jo Lene Leow, Chong Poh Heng, Lisa Chu
ALDO WENEDY
PP-66 Usability Evaluation of a smartphone app-based system for enhancing medication adherence in cancer patients
Main-Sup: Asst. Prof. Lita Chew Co-Sup: Dr. Kevin Yap Collaborator: Eskinder Eshetu Ali (Graduate Student)
CHAN SI LING SHARLENE
PP-67 The pattern of opioids usage by patients in home hospice care in Singapore: A retrospective review from 2013-2016
Main-Sup: Asst. Prof. Lita Chew Collaborators: A/Prof. Gerald Koh Dr. Chong Poh Heng
BOEY THENG HIANG
PP-68 A survey on patient adherence to oral epidermal growth factor receptor tyrosine kinase inhibitor therapy
Main-Sup: Asst Prof. Lita Chew Collaborator: Eskinder Eshetu Ali PhD student, NUS Pharmacy
SHEN QIANYU
PP-69 Febrile neutropenia and sepsis in paediatric ALL: A single instituition report from the Ma-S’pore ALL 2003 and 2010 studies
Main-Sup: Asst. Prof. Lim Siew Woon Co-Sup: Ms. Foo Koon Mian Senior Clinical Pharmacist Collaborator: Amanda Lee Clinical Pharmacist, KKH/Pharmacy
ENG JING JIA
Project No Title Supervisor(s) Student Name PharmD-01 Early therapeutic cyclosporine level
influences the incidence and severity of acute graft versus host disease in Asian patients receiving allogeneic haematopoietic stem cell transplantation
Main-Sup: Dr. Ong Pei Shi HO YING SHI
PharmD-02 Predictors for morbidity and mortality in multiethnic Asian incident hemodialysis patients
Main-Sup: A/Prof. Priscilla How YEO YAN TING
PharmD Projects
PharmD-03 Investigation of multi-drug resistant infection predictors and outcomes of elderly admitted from nursing home
Main-Sup: A/Prof. Teng Bee Choon Christine
HENG JIAN WEI
PharmD-04 Impact of timing between insulin administration and meal consumption on glycemic fluctuation and outcomes in hospitalized patients with type 2 diabetes
Main-Sup: A/Prof. Joyce Lee LIM SHU FANG
PharmD-05 Influence of diltiazem on the pharmacokinetics of tacrolimus in relation to pharmaco-genetics in kidney transplant recipients
Main-Sup: Dr. Yau Wai Ping LIM ROU WEI
PharmD-06 Risk factors and outcomes associated with acquisition of polymyxin B resistance (PBR) in patients with carbapenem-resistant Gram-negative bacteria (CRGNB): A matched case-control study
Main-Sup: A/Prof. Andrea Kwa CHANG WEE TING CASSANDRA
PharmD-07 Gentamicin prescribing patterns in pregnancy: a single centre experience in Singapore
Main-Sup: A/Prof. Teng Bee Choon Christine
LEOW YUMEI CYNTHIA
Project No. Title Supervisor(s) Student Name PhD-02 Trends and predictors of guideline-
recommended drug utilization in incident ischemic stroke patients: A population-based study using the Singapore Stroke Registry
Main-Sup: Dr. Yau Wai Ping YEO SEE HWEE
PhD-03 The investigation of cancer stem cell-targeting properties of metal-based compounds
Main-Sup: A/Prof. Giorgia Pastorin MARIA BABAK
PhD-05 Perturbation of arachidonic acid metabolism by antiarrhythmic drugs: Implications in cardiac safety?
Main-Sup: A/Prof. Eric Chan Chun Yong
ANEESH
PhD-06 The level and determinants of self-reported adherence to oral therapies for common cancers at the National Cancer Centre Singapore
Main-Sup: Asst. Prof. Lita Chew Co-Sup: Dr. Kevin Yap
ESKINDER ESHETU ALI
PhD-07 Co-administration of amiodarone and rivarobaxan: a PBPK guided approach for prospective dose adjustment in the presence of complex drug-drug interactions
Main-Sup: A/Prof. Eric Chan Chun Yong
CHEONG JING YI ELEANOR
PhD-08 Biodegradable polymyxin B-loaded phenylboronic acid-functionalized polycarbonate hydrogels for treatment of Pseudomonas aeruginosa infected burn wounds
Main-Sup: A/Prof. Rachel Ee SYBIL AKUA OKYEREWA OBUOBI
PhD-09 Mechanisms of dronedarone-induced cardiac failure exacerbation: Role of mitochondrial toxicity?
Main-Sup: A/Prof. Eric Chan Chun Yong
ANEESH
PhD-10 A continuous and scalable bottom-up process to produce drug nanoparticle formulation for enhanced oral/pulmonary delivery
Main-Sup: A/Prof. Giorgia Pastorin HU JUN
PhD Projects
No. Title Supervisor(s) Student Name 1 One-pot glovebox-free synthesis,
characterization, and self-assembly of novel amphiphilic poly(sarcosine-beta-caprolactone) diblock copolymers
Main-Sup: Prof. Zhenjiang Li Vice Dean of College of Biotechonology and Pharmaceutical Engineering
RUI CHEN Undergraduate student (Senior) Major: Biochemical Engineering Department of Biochemical Engineering, College of Biotechnology and Pharmaceutical Engineering
2 Metabolic profiling of the Rhizopus ozyrae’s fumaric acid production influenced by xylose
Main-Sup: Prof. Qing Xu
JIAMIN NING Undergraduate student (Junior) Major: Pharmaceutical Engineering Department of Biochemical Engineering, College of Biotechnology and Pharmaceutical Engineering
Posters from Nanjing Tech University:
ORGANIZING COMMITTEE:
Chairperson: Dr. Yap Yi-Lwern, Kevin
Secretariats: Ms. Winnie Wong Ms. Wong Mei Yin Ms. Chew Ying Ying Advisors: Prof. Christina Chai Li Lin A/Prof. Go Mei Lin A/Prof. Ho Han Kiat
Asst. Prof. Wee Hwee Lin Dr. Ong Pei Shi Dr. Liew, Celine Valerie Mr. Lee Sze Han
Student coordinators: Yap Ting Jian Charmaine Goh Mei Xian Goh Zhang-He Vanitha Selvarajan Tran Thi Ngoc Quy
STUDENT ORGANIZING COMMITTEES:
15th Pharmacy Postgraduate Committee
President: Vanitha Selvarajan
Secretary: Tran Thi Ngoc Quy
Treasurer: Sin Jia En Valerie
Event Coordinators: Muthukumar Karuppasamy Cheong Jing Yi Eleanor
56th NUS Pharmaceutical Society
Academic Director: Goh Zhang-He
Academic Vice Directors: Liew Jia Hui Sarah Xing Huiwen
Sharon Goh Pei Xuan Yap Ting Jian
Academic Committee: Amos Lim Boon Hao Annabel Er Wan Zhen Benedict Ang Chen Yee Choy Ying Feng Han Qi En Joyi Lee Yi Jie Kimberly Chong Yen Ling Low San Zeng Neo Kai Sheng Ng Xiang Yun Nicholas Chiam Chia
Kiat Ong Zhang Ting
Pang Yong Xian Sia Ming Kian Tai Jia Ching Tan Aik Edwin Tan Lien Chew Tiang Yi Long Yvonne Ng Wan Xin
Academic Secretary/Treasurer: Aurora Chan Wing Dan
Marketing/Public Relations Director:
Charmaine Goh Mei Xian
Marketing/Public Relations Vice-Director: Tan Jun Jie Soo Wei Marketing/Public Relations Committee: Andre Lee Benjamin Cheng Yue
Xuan Cassandra Yeo Rui Si Wang Han Lu
International Relations Director: Chong Jin Jian
International Relations Vice-Director:
Chan See Kei Lai Wan Lin Angeline Muhammed Siddiq Mashkur Bin Hassan
Emcees: Kamonlawan Chomchopbun
Siow Ru Shan Carin
Stephen Ahenkorah Benjamin Cheng Yue
Xuan
Photographers: Ngai Mun Hong Wee Hai Ning
We wish to thank the following for their support and contributions:
Prof. Chai Li Lin Christina (Head, Department of Pharmacy)
Ms. Chew Ying Ying (Senior Manager)
Ms. Napsiah Binte Suyod (Management Assistant Officer)
Ms. Chan Wei Ling Kelly (Management Assistant Officer)
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