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Global J Res. Med. Plants & Indigen. Med. | Volume 6, Issue 5 | May 2017 | 75–88
Global Journal of Research on Medicinal Plants & Indigenous Medicine || GJRMI ||
ISSN 2277-4289│ www.gjrmi.com │International, Peer reviewed, Open access, Monthly online Journal
A CRITICAL REVIEW ON PRAMEHA MANAGEMENT
FROM VARIOUS COMPENDIA
Kavita Kumari1, Suman Singh2, Bhupesh Patel3
1M.D. Scholar, Department of Dravyaguna, I.P.G.T & R.A., Gujarat Ayurved University, Jamnagar, Gujarat,
India -361 008 2 PhD Scholar, Department of Dravyaguna, I.P.G.T & R.A., Gujarat Ayurved University, Jamnagar, Gujarat,
India -361 008 3Assistant Professor, Department of Dravyaguna, I.P.G.T & R.A., Gujarat Ayurved University, Jamnagar,
Gujarat, India -361 008
*Corresponding Author: Email: kavitasohu702@gmail.com; Mobile: +91-7284021574
Received: 09/04/2017; Revised: 24/05/2017; Accepted: 30/05/2017
ABSTRACT
Prameha is defined as a disease, with excessive urination and turbidity. 20 types of Prameha is
described by Acharyas, 4 are due to Vata, 6 due to Pitta and 10 are caused by Kapha. Though it is
Yapya (not totally curable / difficult to cure) disease, but the prolonged Ayurvedic treatment will
help the person to prevent its complication and lead a healthy life. This review work is an attempt to
compile and present Prameha management in systematic manner with scientific observations from
various compendia and web searches. In present study, different formulations as well as single drugs
were compiled from 10 different compendia, for the treatment of Prameha. Analysis of the compiled
data shows that, about 150 formulations (Rasa-43, Kwatha-41, Vati-15, Ghrita-12, Churna-11,
Avleha-10, Taila-6) has been described and 40 single drugs are being used, among them maximum
drugs are of plants origin (28) followed by minerals (10) and animal origin (1). Some of these drugs
are reported for various pharmacological activities like antidiabetic (13), anti-hyperlipidaemic (4),
antioxidant (10), immune-modulatory activity (7) etc. Prameha can be correlated with the disease
Diabetes mellitus of modern science. Different properties and mode of action of these drugs
compiled, may give a lead to find out new approaches for the treatment of Prameha and helpful to
prevent its complications.
KEYWORDS: Antidiabetic, Diabetes, Madhu, Prameha, Yapya
Review Article
Cite this article:
Kavita Kumari*, Suman Singh, Bhupesh Patel (2017), A CRITICAL REVIEW ON
PRAMEHA MANAGEMENT FROM VARIOUS COMPENDIA,
Global J Res. Med. Plants & Indigen. Med., Volume 6 (5): 75–88
Global J Res. Med. Plants & Indigen. Med. | Volume 6, Issue 5 | May 2017 | 75–88
Global Journal of Research on Medicinal Plants & Indigenous Medicine || GJRMI ||
INTRODUCTION:
Ayurvedic classics have laid importance
upon the etiological factors, their role in
vitiations of Dosha (body humour) and Dushya
(body tissues) which manifest disease
conditions. Besides this, some conditions are
also considered due to Beeja dushti (defects in
the gametes) i.e. Prameha (urinary disorder)
and Arsha (piles). Prameha are categorized into
two types based upon its origin i.e. Sahaja
(congenital) and Apathyanimittaja (due to over
eating and poor habits). In these two categories,
former occurs due to Beeja dushti and latter
one due to improper diet and lifestyle. In
Ayurvedic classics, detail description of
etiological factors like excessive intake of
heavy, unctuous and saline foods, new cereals
and fresh wine consumption in large quantity,
sedentary life style, not indulging in any sort of
physical and mental exercise and not
undergoing bio-purification of body are
mentioned for Prameha (Acharya YT, 2011).
These etiological factors aggravate Kapha
(watery element), Pitta (fiery elements or bile),
Meda (fatty tissue), Mamsa (muscles) and
obstruct the normal pathway of Vata (air
elements), agitated Vata carries the Ojas
(immunity) to Basti (urinary bladder) and
causes Prameha. Which ultimately leads to
Madhumeha (Acharya YT, 2011). Prameha is
defined to be characterized with excessive
urination (both in frequency & quantity) and
turbidity (Acharya YT, 2009). Acharya
Vagbhata further clarifies that nature of the
turbidity may vary depending upon the body
reaction with the Doshas (Shashtri
Harisadashiva, 2010). Acharyas have classified
Prameha into two categories on management
basis, first who are Sthula (obese) and strong
and second one those who are emaciated
(Krisha) and weak. The patient belonging to
the latter category should be given Brimhana
(nourishing) and Shamana chikitsa (pacifying
therapy) while patients of the former category
have more Dosha in the body, should be
administered Shodhana Chikitsa (elimination
therapy) (Acharya YT, 2011). Seers of
Ayurveda have considered that every Prameha
with passage of time is converted into
Madhumeha. Therefore, Prameha can be
correlated with the early stage of diabetes
mellitus. Diabetes describe as a metabolic
disorder of multiple etiologies characterized by
chronic hyperglycemia with disturbance of
carbohydrate, fat and protein metabolism
resulting from defects in insulin secretion,
insulin action or both. Diabetes is a growing
public health problem in both developed and
developing countries. Globally, an estimated
422 million adults are living with diabetes
mellitus, according to the latest 2016 data from
the World Health Organization (WHO) (WHO,
2016). Diabetes prevalence is increasing
rapidly; the number is projected to almost
double by 2030 (Wild S, 2004). Type 2
diabetes makes up about 85–90% of all cases
(Shlomo Melmed, Kenneth Polonsky, P.Reed
Larsen, Henry Kronenberg, 2011). Until
recently, India had more diabetics than any
other country in the world, according to the
International Diabetes Foundation (Gale,
2010), although the country has now been
surpassed China to the top spot (BBC, 2010).
Diabetes currently affects more than 62 million
Indians, which is more than 7.1% of the adult
population (IANS, 2014). Nearly one million
Indians die due to diabetes every year (Gale,
2010). The high incidence is attributed to a
combination of genetic susceptibility plus
adoption of a high-calorie, low-activity lifestyle
by India's growing middle class (Kleinfield
NR, 2006).
Though patho-physiology of diabetes
remains to be fully understood, experimental
evidences suggest the involvement of free
radicals in the pathogenesis of diabetes
(Matteucci E, 2000) and more importantly in
the development of diabetic complications
(Oberley LW, 1988, Lipinski B, 2001). In
search of natural origin medicines for
combating such metabolic syndromes with
fewer side effects, there has been an
exponential growth in the field of herbal
medicine and these drugs are gaining
popularity both in developing and developed
countries. Many traditional medicines in use
are derived from medicinal plants, minerals and
organic matter (Grover JK et al., 2002). Hence,
Global J Res. Med. Plants & Indigen. Med. | Volume 6, Issue 5 | May 2017 | 75–88
Global Journal of Research on Medicinal Plants & Indigenous Medicine || GJRMI ||
present review is an attempt to update
information regarding management of Prameha
from various compendia of medieval period
with evidence based experimental and clinical
studies on diabetes mellitus.
MATERIAL AND METHODS
In present study, compound formulations as
well as single drugs, indicated for Prameha
management were compiled from
Vaidyajeevana (Sharma PV, 2013),
Bhavaprakashasamhita (Mishra Brahmasankar,
2005), Basvarajeeyam (Pandey Gyanedra,
2010), Vyadhinigraha (Giri Kapildev, 1999),
Chamatkara chintamani (Brahmananda
Tripathi, 2006), Yogachintamani (Dattaram,
2003), Yogaratnakara (Shashtri Lakshmipati,
2010), Vaidyarahasya (Tripathi Indradev,
2000), Bhaishjyaratanavali (Mishra
Siddhinandan, 2011), Sahasrayoga (Arya
mahendrapalsingh, 1990). Various research
journals and books were referred to gather the
update information regarding scientific
documentation of the role of these drugs in the
prevention and management of Prameha. The
recorded data are presented in a scientific
manner with regards to their Sanskrit name,
dosage form, dose, vehicle and reported
research activity.
RESULTS & DISCUSSION
Analysis of the compiled data shows that,
about 150 compound formulations (Rasa-43,
Kwatha-41, Vati-15, Ghrita-12, Churna-11,
Avleha-10, Taila-6) and 40 single drugs has
been described, among them maximum drugs
are of herbal origin (28) followed by mineral
(10) and animal origin (1). Mainly used dosage
form is Kwatha (decoction) and Anupana
(vehicle) is Madhu (Honey) among the
observed data (Table 1). Honey possesses
Kapha-Medanashaka property and it is best
vehicle described in Ayurvedic classics as they
aid in channelizing the drugs to every Dhatu
(body tissues) and Srotas (channels of the
body) of the body (Acharya YT, 2011). Honey
has been shown to scavenge reactive oxygen
species, ameliorate oxidative stress and reduce
hyperglycaemia. (Beretta G et al., 2007,
Erejuwa OO et al., 2010a). While honey
supplementation in diabetic rats ameliorates
renal oxidative stress independent of the dose,
its hypoglycaemic effect is dose-dependent
(Erejuwa OO et al., 2010b). It is hypothesized
that the fructose and oligosaccharides present
in honey might in some way contribute to the
observed hypoglycaemic effect. (Erejuwa OO
et al., 2012, Erejuwa OO et al., 2011a). In
addition, honey supplementation ameliorates
several metabolic derangements commonly
observed in diabetes. These include reduced
levels of hepatic transaminases, triglycerides
and glycosylated haemoglobin (HbA1c) as well
as increased HDL cholesterol. (Erejuwa OO et
al., 2011b, Chepulis L, 2008, Busserolles J,
2002). Most of these drugs possess Rasayana
(rejuvenator) action which is followed by
Deepana (appetizer), Chakshushya (good for
eye health), Balya (improves strength) etc.
Some of these drugs are reported for various
pharmacological activities like antidiabetic
(13), anti-hyperlipidaemic (4), antioxidant (10),
immunomodulatory (7) etc. (Table 1) One of
the etiologic factors implicated in the
development of diabetes and its complications
is the damage induced by free radicals. Free
radicals are capable of damaging cellular
molecules, DNA, proteins and lipids leading to
altered cellular functions. Natural antioxidants
strengthen the endogenous antioxidant defenses
from reactive oxygen species (ROS) and
restore the optimal balance by neutralizing the
reactive species. Many recent studies reveal
that antioxidants capable of neutralizing free
radicals are effective in preventing
experimentally induced diabetes in animal
models (Kubisch HM, et al.,1997, Naziroglu M
et al., 2001) as well as reducing the severity of
diabetic complications (Lipinski B, 2001)
hence an anti-diabetic compound with
antioxidant properties would be more
beneficial. Components of the immune system
are altered in type-2 diabetes (T2D), with the
most apparent changes occurring in adipose
tissue, liver, pancreatic islets, in vasculature
and circulating leukocytes. These
immunological changes include altered levels
of specific cytokines and chemokines, changes
in the number and activation state of various
Global J Res. Med. Plants & Indigen. Med. | Volume 6, Issue 5 | May 2017 | 75–88
Global Journal of Research on Medicinal Plants & Indigenous Medicine || GJRMI ||
leukocyte populations and increased apoptosis
and tissue fibrosis. Preliminary results from
clinical trials with salicylates and interleukin-1
antagonists (Claus ML et al., 2007) support this
notion and have opened the door for immune-
modulatory strategies for the treatment of T2D
that simultaneously lower blood glucose levels
and potentially reduce the severity and
prevalence of the associated complications of
this disease (Marc YD and Steven ES, 2011).
Hence, drugs like Haridra (Curcuma longa)
(Jennifer RA et al., 2012), Guduchi (Tinospora
cordifolia) (K. Salkar et al., 2014), Amalaki
(Phyllanthus emblica) (Chatterjee A, 2011),
Bala (Sida cordifolia) (Meera Sumanth and SS
Mustafa, 2009), Shatavari (Asparagus
racemosus) (Gautam M et al., 2009) etc.
possess immune-modulatory activity which can
be helpful in preventing various associated
complications of diabetes thereby maintains
quality of life. (Table 1)
Table 1 – Single drugs of plant origin indicated in the management of Prameha
S.n
o.
Drugs Botanical
source
Dosage
form
Vehicle Actions Reported activity
1. Haritaki Terminalia
chebula Linn.
(Combretaceae)
Churna
(Powder)
Madhu
(Honey)
Deepana
(appetizer), Medhya
(nootropic),
Rasayana
(rejuvenator),
Chakshushya,
Anulomana
Hypolipidaemic (V.
Maruthappan and K.
Sakthi Shree, 2010),
Antioxidant
(Bibhabasu Hazra et
al., 2010),
Antidiabetic
(MuraliYK et al.,
2007)
2. Haridra Curcuma longa
Linn.
(Zingiberaceae)
Kwatha
(Decocti
on)
Raktashodhaka,
Twakdoshahara,
Shothahara,
Deepana
(appetizer), Grahi,
Vishaghna
Antioxidant
(R.Selvam et al.,
1995),
Immunomodulator
(Jennifer RA et al.,
2012), Anti-diabetic
(Rai PK et sal.,
2010),
Hypolipidaemic
(Faizal IP et al.,
2009)
3. Palasha
pushpa
(flower)
Butea
monosperma
(Lamk.)Taub.
(Fabaceae)
Kwatha
(Decocti
on)
Sugar Deepana
(appetizer), Vrishya
(aphrodisiac), Sara
Anti-oxidant (Prasad
GJ et al., 2013),
Antidiabetic (Chusri
Talubmook and
Nopparat B, 2012)
4. Guduchi Tinospora
cordifolia
Willd. (Menispermaceae)
Swarasa
(Juice)
Madhu
(Honey)
Tridoshahara,
Deepana
(appetizer),
Rasayana
(rejuvenator),
Grahi,
Chakshushya,
Medhya (nootropic)
Immunomodulator
(K. Salkar et al.,
2014),Antidiabetic
and hyperglycemic
(Wadood N et al.,
1992), Antioxidant
(Methew S and
Kuttan G, 1997)
Global J Res. Med. Plants & Indigen. Med. | Volume 6, Issue 5 | May 2017 | 75–88
Global Journal of Research on Medicinal Plants & Indigenous Medicine || GJRMI ||
5. Guduchi
satva
Tinospora
cordifolia
Willd. (Menispermaceae)
Satva Madhu
(Honey)
Tridoshahara,
Deepana
(appetizer),
Rasayana
(rejuvenator),Grahi,
Chakshushya,
Medhya (nootropic)
Immunomodulator
(Bhatnagar SP et al.,
2010), Antioxidant
(Rachana Dwivedi
et al., 2014)
6. Kataka Strychnos
potatorum
Linn.f.
(Loganiaceae)
Seed
powder
Chakshushya Antidiabetic
(Dhasarathan P,
2011), Antioxidant
(Sanmugapriya E
and Venkataraman,
2006)
7. Aamalaki Phyllanthus
emblica Linn. (Euphorbiaceae)
Swarasa
(Juice)
Madhu
(Honey)and
haridra
churna
(turmeric
powder)
Rasayana(rejuvenat
or),
Vrishya(aphrodisiac
), Chakshushya,
Deepana (appetizer)
Antioxidant (Satio
K et al., 2008),
Antidiabetic
(Suryanarayana P et
al., 2007),
Hypocholesteromic
(Kim HJ et al.,
2005),
Hypolipidaemic
(Mathur R et al.,
1996),
Immunomodulatory
(Chatterjee A, 2011)
8. Bala Sida cordifolia
Linn.
(Malvaceae)
Kwatha
(Decocti
on)
Lodhra
churna
(lodhra
powder)and
Madhu
(Honey)
Balya(improves
strength), Vrishya
(aphrodisiac),
Grahi, Brimhana,
Prajasthapana
Antioxidant
(Sharma HM et
al.,1992),
Antidiabetic (Kanth
VR and Diwan PV,
1999) and
Hypercholesteromic
(Kaur G et al.,
2011), Adaptogenic
(Meera Sumanth
and SS Mustafa,
2009),
Immunomodulator
(Meera Sumanth
and SS Mustafa,
2009)
9. Shatavari Asparagus
racemosus
Willd.
(Liliaceae)
Swarasa
(Juice)
Milk Balya (improves
strength), Rasayana
(rejuvenator),
Netrya, Shukrala,
Stanyakara
Antioxidant (Lalana
Kongkaneramit et
al., 2011),
immunomodulator
(Gautam M et al.,
2009)
Global J Res. Med. Plants & Indigen. Med. | Volume 6, Issue 5 | May 2017 | 75–88
Global Journal of Research on Medicinal Plants & Indigenous Medicine || GJRMI ||
10. Bhumiama
laki
Phyllanthus
amarus
Schum.et.Thon
n (Euphorbiaceae)
Churna
(Powder)
Maricha
churna
(Piper
powder)
Kasahara,
Shwasahara,
Rasayana
(rejuvenator)
Hypoglycemic (AA
Adeneye et al,
2006), Antidiabetic
(AA Shetti et al.,
2012), Antioxidant
(Lim Y and
Murtijaya, 2007)
11. Bilvapatra Aegle marmelos
Linn.(Rutaceae)
Swarasa
(Juice
Sugar Balya (improves
strength),Grahi,
Deepana
(appetizer),
Pachana
Antidiabetic (M.
C.Sabu and
Ramadasan Kuttan,
2004),Antioxidant
(Sharmila upadhya
et al.,
2004),Immuno-
modulator (HV
Govinda and SMB
Asdaq, 2011)
12. Parijata Nyctanthes
arbortristis
Linn. (Nyctanthaceae)
Kwatha
(Decocti
on)
Madhu
(Honey)
Anulomana Antioxidant (Rathee
JS et al., 2007),
Antidiabetic
(Pattanayak C et al.,
2012),
Immunomodulator
(Marikani kannan
and Ranjit Singh
AJA, 2010)
13. Agnimanth
a
Clerodendrum
phlomidis Linn.
(Verbenaceae)
Kwatha
(Decocti
on)
- Anti-hyperlipidemic
(MJ Patel and JK
Patel, 2012),
Antioxidant (Gokani
RH et al., 2010)
14. Nimba Azadirachta
indica A. Juss.
(Meliaceae)
Kwatha
(Decocti
on)
- Deepana
(appetizer), Netrya
Antioxidant(Rao
AD et al., 1998),
Immuno-stimulant
(Ujjwal KD and
Mukherjee R, 2009)
Antidiabetic
(Rasheda Akter, et
al., 2013)
Minerals and herbo-mineral preparations
are fewer in Samhita period with succession of
time their uses are increased which reflects in
compendia of medieval periods. It is observed
that herbo-mineral complexes are more stable
and more interactive which results in faster
therapeutic action and have a longer shelf life.
In the management of Prameha, individual uses
of 9 different minerals were found in referred
compendia (Table 2). These minerals were
prescribed with various Anupana (vehicle) like
Madhu (honey), milk, Triphala etc. In classical
texts, a great emphasis is laid on dosage and
Anupana (vehicle) with which a Bhasma
should be administered. Anupana may possibly
play the key role in the safety of the Bhasma. In
absence of such caution, adverse reaction is
likely (Kapoor R, 2010). Madhu (honey) as
Global J Res. Med. Plants & Indigen. Med. | Volume 6, Issue 5 | May 2017 | 75–88
Global Journal of Research on Medicinal Plants & Indigenous Medicine || GJRMI ||
Anupana (vehicle) brings about quick action
due to its Yogavahi (super-advenient) property
(Chunekar KC, 2004). Minerals were reported
for their antioxidant activity, antidiabetic
activity, immunomodulatory effect etc. in
experimental studies mentioned in table 2.
Frequently used 30 important compound
formulations described in table 3, were found
in referred compendia with different dosage
forms and vehicles. These formulations are
indicated in Prameha, its various types and
many other conditions.
Table 2-Single drugs of mineral origin indicated in the management of Prameha.
S.N Drug Botanical
/English
Name
Anupana (Vehicle) Reported activity
1. Lauha
Bhasma
Iron Madhu (Honey) -
2. Vanga
Bhasma
Calx of Tin Pure Shilajitu Antidiabetic (Soni Chandan et al., 2011)
3. Naga
Bhasma
Lead Calx Madhu,Haridra,Amalaki Antidiabetic (Deshmukh SM, 2013)
4. Shilajitu Asphaltum Milk,Sugar,Honey Immunomodulatory (Ghosal S, 2009),
Hypolipidemic (Trivedi NA, 2004),
Antidiabetic (Trivedi NA, 2004)
5. Abhraka
Bhasma
Calx of Mica Honey,Triphala,Haridra Hypoglycemic activity (Raghava Rao
Gundimeda, 2010)
6. Gandhaka
yoga
Sulphur Puranaguda
(Jaggery),Milk
-
7. Swarna
Makshika
Copper Pyrite Madhu,Guduchisatva Antidiabetic (Singh Neetu et al., 2014)
8. Roupya
Makshika
Iron Pyrite Saradiganabhavna
(Levigation)
Antioxidant
9. Sphatika
Churna
Quartz Stone - -
Table 3-Compound formulations indicated in Prameha
S.no Name Dose & Vehicle Indication Referenc
es of
books*
1. Mehantaka rasa Kshnamatravati,
Mushali, Shatavari rasa,
Navneeta
Vinshati Prameha 7,9
2. Harishankara rasa
1,2
Honey Vinshati Prameha 7,9
3. Pramehakalanala
rasa
250 mg, Gunjakwatha Vinshati Prameha 9
4. Pramehakulantaka
rasa
Milk,Amalakiswarasa Vinshati Prameha,Pandu,Kamla,
Mutrakricchra, Ashmari
9
5. Vasantakusumakara
rasa
Ghrita, Madhu(Honey) Prameha,Ekadasakshaya, Soma roga 7,9
6. Vangeshwara rasa
1,2,3,4
Pippalichurna,Madhu Vinshati Prameha 7,8,9
Global J Res. Med. Plants & Indigen. Med. | Volume 6, Issue 5 | May 2017 | 75–88
Global Journal of Research on Medicinal Plants & Indigenous Medicine || GJRMI ||
7. Maha Vangeshwara
rasa
- Vinshati Prameha, Pandu,
Somaroga, Mutrakricchra, Ashmari
7
8. Jalajamrita rasa Sugar Mutrakricchra, Vinshati Prameha
7
9. Pramehasetu rasa 3 rati (415), with
Triphalachurna-Honey
Vinshati Prameha 9
10. Phalatrikadikwatha Honey(Madhu) All chronic Prameha 2,7,9
11. Triphaladikwatha Honey (Madhu) Vinshati Prameha 4,6,7,9
12. Aakulyadikwatha Honey (Madhu) Vinshati Prameha 10
13. SarjadiKwatha Honey (Madhu) Udakameha 9
14. Manjisthadikwatha Honey (Madhu) Shukra, Raktameha 9
15. Chandraprabhavati
1,2
Karsha, with Ghrita-
Madhu(Honey)
Mutradosha,Pradara, Prameha,
Arsha, Ashmari, Vidradhi,
Pandu,Udararoga
6,7,8,9
16. Gokshuradivati/gug
gulu
- Vataroga, Vatarakta, Mutradosha,
Pradara
2,6,7
17. Induvati 60mg,Honey Madhumeha 8
18. Panchananavati 1 Rati (125mg) Vinshati Prameha, Kushtha, Shoola,
Gulma, Jwara
8
19. Eladi Churna With Rice water Vinshati Prameha 9
20. Sinhamritaghrita - Madhumeha, Kushtha, Bhagandara 2,7
21. Dhanvantraghrita 6-12gm,With hot milk or
hot water
Prameha, Kushtha,
Bhagandara,Unmada, Apasmara
2,9,10
22. Shalmalighrita 12 gm, With hot milk or
hot water
Vinshati Prameha (Shukrameha),
Napuskata, Dhatukshya,Kasa
9
23. Arjunadyaghrita - Pittaja Prameha 2,7
24. Dadimadyaghrita
1,2,3
6-12gm,With hot milk or
hot water
Prameha, Kushtha, Kasa, Shwasa,
Hikka, Ashmari
2,9
25. Ashvagandhapaka - Prameha,JeernaJwara, Shotha,
Gulma,Vata-Pitta roga
6,7
26. Gokshuradyavleha 4 Tola(96gm) Ashmari, Madhumeha, Mutradaha,
Vibandha
2,7
27. Drakshapaka 2 Karsha(48gm) Prameha,Vibandha,Pittajaroga 7
28. Ashwagandhapaka Prameha, Jwara, Shotha,
Agnideepaka
7
29. Lodhrasava 1 Pala (96gm) Kapha-Pitta prameha, Grahani,
Arsha,Pandu
7
30. Devdarvyadiarishta - Prameha, Vataroga, Grahani, Arsha,
Dadru
7,9
*Vaidyajeevana (1), Bhavaprakashasamhita (2), Basvarajeeyam (3), Vyadhinigraha (4), Chamatkarachintamani (5),
Yogachintamani (6), Yogaratnakara (7), Vaidyarahasya (8), Bhaishjyaratanavali (9), Sahasrayoga (10)
CONCLUSION
Plants have always been an important
source for finding new remedies for human
diseases. Among hundreds of plants that have
been studied for diabetes, only a small fraction
has been tested in animal studies and is under
clinical trials. The drugs described in this
paper, particularly Terminalia chebula, Butea
monosperma, Shilajatu and Vanga Bhasma had
some clinical evidence for their antidiabetic
effects. Therefore, it seems that physicians can
rely on these single drugs as well as
formulation, at least as complementary
therapeutics, along with current hypoglycemic
drugs to improve management of diabetic
patients. The observed result may be helpful in
planning further scientific studies about the
efficacy of these drugs on prevention as well as
management of Prameha (Diabetes).
Global J Res. Med. Plants & Indigen. Med. | Volume 6, Issue 5 | May 2017 | 75–88
Global Journal of Research on Medicinal Plants & Indigenous Medicine || GJRMI ||
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