Patents at Mach 2: Technology on the Cutting Edge

Drexel Experience in a Biomedical Engineering classJay Bhatt, Drexel UniversityJune 22, 2008

American Society for Engineering Education

Drexel’s Engineering Programs

All major engineering disciplinesBiomedical engineering, Science, and

Health systemsInterdisciplinary focus is increasing

(Nanotechnology, Biomaterials, Bionanotechnology, Biomechanics, etc.)

Undergraduate ResearchGraduate Research

Case Study - Biomaterials

Course Sequence3 Quarters = 2 Semesters

Challenges Interdisciplinary FieldDiverse Student BackgroundLack of appropriate textbooks

Biomaterials courses – Biomaterials I – Fall Term

Prof. Papazoglou teaches the three course sequence

60-70 students Biomaterials propertiesVarious types of materials such as

polymers, hydrogels, ceramics, and glasses

Controlled Drug Release systems

Biomaterials courses – Biomaterials II – Winter Term

Patents and Intellectual propertyStudents needed to use what they

learned in the Fall term as well as search for patents

Cancer nanotechnology as an exampleGroup ProjectsBlog site for patents

Biomaterials courses – Biomaterials II – Winter Term

Student Assignment List and briefly describe 5 patented technologies for controlled drug delivery in cancer chemotherapy (last 7 years)

List and briefly describe any patent on drug delivery based on nanotechnology for drug delivery of cancer chemotherapy (last 5).

Determine uniqueness of each patentFind research literature using sources

learned during the Fall term

Patent searching

Using US Patents-Advanced Feature ABST/(Cancer and Drug and Delivery) ABST/(controlled and drug and delivery) and (cancer and

chemotherapy) ABST-Abstract field that contains brief summary of patent invention The abstract contains many of the relevant words of a patent

United States Patent 7,303,739Erion,   et al. December 4, 2007 Prodrugs for liver specific drug delivery. See handout.

Patent Searching

Patent ClassificationCurrent U.S. Class:424/9.1 ; 424/1.11; 424/1.65; 424/600; 424/601; 424/9.2; 514/7

Observe U.S. Classes. What is a classification schedule?

Patents are classified (organized) in the U.S. by a system using a 3 digit class and a 3 digit subclass

They describe every similar grouping of patent art. A single invention may be described by multiple classification codes For example, Class:424/9.1 ; 424/1.11; 424/1.65; 424/600; 424/601;

424/9.2; 514/7

See Classification Help and Glossary

How does classification help in searching for patents?

Patent Searching using classes and subclasses

United States Patent 7,303,739Prodrugs for liver specific drug delivery. See handout

Current U.S. Class:424/9.1 ; 424/1.11; 424/1.65; 424/600; 424/601; 424/9.2; 514/7

From USPTO site, go to Class Numbers Only Page

(Path: Patents > Guidance, Tools, and Manuals > Classification US Classes by Number Menu)

Class   424: DRUG, BIO-AFFECTING AND BODY TREATING COMPOSITIONSSubclass 9.1          IN VIVO DIAGNOSIS OR IN VIVO

TESTING

Clicking on ‘P’ retrieves all patents for class 424 subclass 9.1.

Similarly other patents in different classes can be found

   

Patent Searching

European Patent Office – World PatentsEuropean Patent Office - Advanced Search

‘Cancer Drug Delivery’ as a keyword

NANOPARTICLES FOR CYTOPLASMIC DRUG DELIVERY TO CANCER CELLS Inventor: RADOSZ MARCIEJ (US); SHEN YOUQING (US); (+1) Applicant: UNIV WYOMING (US); RADOSZ MARCIEJ (US); (+2)  EC:  A61K9/51IPC: A61K9/14; A61K9/14  Publication info: WO2007001356 - 2007-01-04

Complex drug delivery composition and method for treating cancer Inventor: MINKO TAMARA (US); SINKO PATRICK J (US); (+1) Applicant:   EC:  A61K47/48H4P; A61K47/48RIPC: A61K47/48; A61K47/48; (IPC1-7): A61K38/17  Publication info: US2005043215 - 2005-02-24

Thank You!

Jay Bhatt

Drexel Universitybhattjj@drexel.edu

With special thanks toDr. Elisabeth Papazoglou,

Drexel University