Business model of the project «Сabinet of fluorescence

diagnostic andPhotodynamic therapy»

The purpose of the project "Early cervical cancer

screening"

2

Bacterial vaginosisVulvovaginal candidosisTrihomoniasisMixed infectionMore

Romani L., Immunity to Fungal Infection 2010

30-35 %

20-25 %10 %

15-29 %10 %

Valuing the problems The frequency of IHC? in the structure of vulvovaginal infections

3

Project

Creating a "Cabinet of fluorescence diagnostic and photodynamic therapy"

Screeaning of. early effective Cervical Cancer

Treatment of genital warts Treatment of VAGINITIS

4

Treatment of genital warts

1 группа (пероральный прием 5-АЛК) (n=37)

2 группа (нанесение 20% мази 5-АЛК) (n=30)

3 группа (применение солкодерма) (n=18)

0%

20%

40%

60%

80%

100%

54 5039

46 5061

полный отсутствие

Кол

ич

еств

о п

аци

енто

к,%

Currently completed clinical studies evaluating the efficacy of fluorescence diagnostic and photodynamic therapy with photosensitizer "Alasens" in women with Genital warts  in 2007 to 2013

270 patients     cured

5

1 группа (пероральный прием 5-АЛК)

(n=37)

2 группа (нанесение 20%

мази 5-АЛК) (n=30)

3 группа (применение солкодерма)

(n=18)

0

5

10

15

20

25

30

57

27

Кол

ич

еств

о п

аци

енто

к, %

Recurrences of genital warts of the vulva after treatment

p<0,05

6

Decision

The device LED Phototherapy "ASF"                   Ltd. "Polironik"

2007 - The patented device LED "APS" LLC "Polironik“

2011 - The patent for the treatment of genital warts of the vulva

The obvious advantages:

Treatment of warts invisible to the eye

Reduction80% relapse

Reducing the time of rehabilitation to

2 weeks

7

The business model

2007 2014 2015 2016

Potential buyers license -

medical diagostic centers

The project will be

patented method of

diagnosis and treatment

  (2013-2014)

Established service

business B2C - Center FD

and PDT (2014-2016)

2013 2014

8

Financial performance

patentingmethod

Certification

Obtainingarrived

2013 20172014 20162015

Building a team

It is necessary: 1) 30 thousand $ - the registration method of diagnosis and treatment 2) 300 thousand $ - the purchase of medical equipment for                                                           FD and PDT (photodynamic therapy) The first profit since the methods in practical health FD and PDT 1 patient - 500 $. The flow of patients at week 15-20

++

++ + + +

..

9

Market Appraisal

In Europe, the number of reported cases during the year of the disease in 20 years has increased from 118 to 200 per 100 000 women

The prevalence among women   25-40% In the U.S. 13 million cases per year By 25 years of age and 50% of women

suffer at least one episode of the disease The peak incidence of IHC observed in

the 3rd and 4th  decades of women's lives

Estimated cost of one procedure = $ 200The required number of procedures for the

patient = 4

10

Evaluation of competitors

Adverse effects

The cost of treatment

The probability of

relapse

Treatment Period

Solkoderm

Diflukan

PDTdrugAlasens

3-5 day

3-7 day

4 day

Systemimpact

Systemimpact

localapplication

80%

80%

35%

300$

250$

300$

11

Partners papers

Federal State Budget Institution "Research Center for Obstetrics, Gynecology and Perinatology" Ministry of Healthcare and Social Development of the Russian Federation

First Moscow State Medical University I.M. Sechenov Laser Biospectroscopy Lab., NSC A.M. Prokhorov General Physics Institute Russian Academy of Science 

Universite de Lorraiene, CRAN, ENSEM, France

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TEAM

Dr. Gennady T. SUKHIKH, MD, PhD, Professor Director Academician of Russian Academy of Medical Sciences

Doctor- Aslanyan K.O.Maria Kholodtsova

PhD, professor - Apolikhina I.A.

PhD, professor -Loshonov V.B.