A Next-Generation Platform Disrupting Healthcare by Maximizing Patient Outcomes and Care Delivery While Profoundly Reducing the Cost of Healthcare

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Beyond patient support & medication adherence…

Maximizing patient happiness & outcomes…via patient engagement & empowerment

www.rxandyou.comWWW.BIOINFORMATIX.IOOCTOBER 2016

http://www.rxandyou.com/

The Problem: Three Core Issues in Medication Delivery +

Medication Non-Adherence

Poly-Provider & Poly-Pharmacy

Drug Interactions & Adverse Events

Medication Non-Adherence – On average, 50% of Americans do not take their drug regimens as prescribed and fall off their treatment path, costing payers $5K each per year; 60% simply forget how to follow the path.

Drug Interactions & Adverse Events – Prescription drug interactions kill 180,000 Americans yearly; it is the 4th leading cause of death.

Poly-Provider – The average American adult sees 18 providers, 28 providers for older or sicker Americans; many don’t know of each others’ existence, let alone what they’re doing.

2OCTOBER 2016 BIOINFORMATIX.IO - STRICTLY CONFIDENTIAL

Three preventable health-management issues cost approximately 420,000 lives and US$664 billion per year:

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Introducing: A Complete Patient Engagement And Safety System A Single Solution with 8 Modules that Engage Patients in Real-time on Preferred Devices to Prevent Issues, Monitor and Report Events, and Coordinate Care

OCTOBER 2016 BIOINFORMATIX.IO - STRICTLY CONFIDENTIAL

AdverseDrug

Interactions

Interaction Screener

Medication Non-

Adherence

Regimen Reminder

Adherence Barriers

Non-adherence

query, reporting

Confused Patients

Micro-targeted Patient

Education

Complex Healthcare

System

Interchange for all

Docs/Meds Info

Adverse Drug

Events

Direct e-reporting

of AEs

Lack of Cross

Provider Visibility

Cross Provider

Care Coordinatio

n

Failure to Surface Adverse

Outcomes

Predictive Analytics

Problems

Solutions

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What does it do for patients? Engage in Real-time on Preferred Devices to Monitor Medication Events & Alert Providers to Prevent Medical Consequences


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What does it do for providers? Engage Patients in Real-time on Preferred Devices to Monitor Medication Events & Alert Providers to Prevent Medical Consequences


Gaining Traction & Ready to Scale Rx&You is complete, with a scalable architecture and AI innovations that are attracting customers and earning national award nominations

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1. Built and Tested 2. Starting Pilots 3. IP Locked

Counsel to…

4. Deep AI 5. Super Scalable

+

= Personalized Medicine

B2B2C +Payers +

Pharma +Providers =

Largest Medication

Big Data Repository

In 18-24 mo

7BIOINFORMATIX.IO - STRICTLY CONFIDENTIALOCTOBER 2016

GTM: Scalable, Innovative Sales Model Offer: To only charge a % of savings generated -- at 20%, that is potentially $10B/yr.

Medical Insurers

Workers’ Comp.

Insurers

Medical Research Centers

Pharmas

National Health

Services

Patients: 20-80M EachSavings: $1-4B yearNPV: $200-800M year

Patients: 20-80M EachSavings: $1-4B yearNPV: $200-800M year

TBD Value TBD Value

Patients: 1-4M EachSavings: $5-20M yearNPV: $200-800M year

x30

x12

x12

x100 x12

OCTOBER 2016

What could this mean? Lives Saved One US Payer = 25,000 lives saved per yearOne Country NHS = 23,000 lives saved per year

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10 Largest Medical Insurers:

1. Zurich2. Express Scripts3. United4. Aviva5. Axa6. Anthem (BC/BS)7. Aetna8. AIA9. Allianz10. Humana

= up to $4 billion in annual licensing fees at 20% of cost savings

What could this mean? Billions Saved Billions in New Profits for US Insurers –charts below model one insurer’s savings

OCTOBER 2016 9BIOINFORMATIX.IO - STRICTLY CONFIDENTIAL

10 of top 30 National Health Services:

1. Norway2. Japan3. United Kingdom4. Sweden5. Saudi Arabia6. Canada7. Italy8. Portugal9. Spain10. UAE, Kuwait & Bahrain

= Up to $1.6 billion in annual licensing fees at 20% of projected cost savings

Optimal for National Health Services Billions in Savings for National Health Services – below is a typical model


Appendix


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Scale of these problemsMedication Adherence + Pharmacovigilance + Care Coordination


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Our Intentions & TrajectoryDo Well while Doing Good

$40m net earnings$200m valuation50m patients engaged25,000 lives savedAugust 2017

$150m recurring revenue$1.4B payer savings100m patients engaged1m AE identifiedAugust 2018 $1B valuation

$3B in payer savings#1 Big Data med dbDecember 2018


A Competitively Superior Solution

Delivers Big Data

Regimen reminders

E-reports adverse events ?

Patient Education ?

Poly-provider ?

Care coordination ?

Mobilized (iPad, iPhone)

Drug interaction screens ?

AI to Detect & Prevent Risks ?

Licensees – Who pays? Patients Patients & Providers Patients Providers Payers & Pharma

Ability to Pay


The Pharma Problems we SolveAn Inter-departmental Enterprise Intelligence Platform

Clinical Trial Departments1. Creates single-view to disparate clinical trials data in real-time;2. Standardizes data types and meanings across clinical trials and stores for long-term re-use and

R&D;3. Maximizes clinical trial outcomes by maximizing medication adherence;4. Using TSQ measurements attached to each patient regimen, creates data to comparatively rank

every med by effectiveness, value, and safety;Clinical Care or Patient Support Departments5. Engages patients in real-time to always know how to take meds eliminating up to 60% of non-

adherence;6. Could prevent nearly 100% of drug-drug interactions;7. Can predict patients’ probability of becoming non-adherent and intervene to prevent;Marketing Departments8. Freely distributes and tracks patient ed, micro-targeting on preferred device to ensure every

patient gets all materials regimen-wide;9. Learn how getting the right info to the right patient at the right time improves clinical outcomes;Regulatory Departments10. Maximizes the percentage of adverse-events that get timely reported;11. Maximizes the qualitative information (e.g., other meds) associated with adverse events; and,12. Maximizes the timeliness of AE reporting to all healthcare teams, manufacturers, and public

health agencies.OCTOBER 2016 17BIOINFORMATIX.IO - STRICTLY CONFIDENTIAL

Technology

A Next-Generation Platform Disrupting Healthcare by Maximizing Patient Outcomes and Care Delivery While Profoundly Reducing the Cost of Healthcare