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Introducing the EVOQ LC-Triple Quadrupole

The New Game Changing LC Triple Quad from

Bruker

Bradley Duruttya

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Introducing the EVOQ LC-TQ

EVOQ QubeTM

EVOQ Elite

• Bruker Triple Quadrupole MS• VIP Heated-ESI• Active Exhaust• IQ Dual Ion Funnel• PACER Software• Mass Range: 10-1250 amu

• Bruker Analytical LC• Advance HPLC (8000 psi)• Advance UHPLC (15000 psi)• Advance UHPLC with OLE (15000 psi)

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One Mission

EVOQ was designed for a singular purpose – to reliably quantify thousands of real samples in the fastest ‘sample-to-report’ time possible.

Food Testing

Environmental Testing

Toxicology

Discovery PK

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Keys to Achieving Mission

Sustained High-Sensitivity• Orifice interface, Active Exhaust, IQ Dual Ion Funnel and VIP-HESI

Increased Capacity through Higher Robustness• High-sensitivity, Flat-tuning IQ Dual Ion Funnel

Fastest ‘Sample-to-Report’ time• Pacer software with Exception Based Data Review

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Active Exhaust vs Equine Plasma – NO DIVERT VALVE USED

• 500 equine plasma samples analyzed with four calibration curves, two bracketing, two spread between samples.

• No divergence between calibration curves run before and after samples were run.

Picture of ion source after running 500 equine plasma samples and 4 calibration

curves.

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A Picture is Worth a Thousand Words

Picture of the EVOQ LC-TQ ion source after running 500 equine plasma samples and 4 calibration

curves.

Game-Changing Performance

Stays cleaner maintains Sensitivity

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Improved Dual Ion Funnel Design

Inter-laced Quadrupole Dual Ion Funnel• Linear, on-axis design of the IQ dual ion funnel virtually eliminates

instrument-to-instrument tune variability.• IQ dual ion funnel does not require DC; no impact on tuning

parameters after running hundreds of matrix rich samples.• Less tuning, Less cleaning, Less maintenance equals more

robustness and more samples

User benefit provided by Bruker• Effortlessly transfer methods between EVOQ instruments.• Save time by eliminating re-tuning.

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Sustained Sensitivity: 5-1000fg Alprazolam in Rat Plasma On Column

5-50fg curve (n=3)

Full Calibration Range

Resp.Factor

EVOQ Elite with Advance HPLC500uL/min LC flow rate 5-90% Acetonitrile (0.1% Formic) in 1.8min C-18, 3u, 2.1x50, ACE column2uL injected

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PACER Software allows Faster Review

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See more on our Microsite

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Game Changing Performance for the Business of Quantitation

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Questions

Thank you