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Presentation given by Teresa Sardon from Anaxomics Biotech SL in the framework of the Emergence Forum Barcelona Biocat organized the Barcelona Emergence Forum (April 10-11th, 2014, Congress Palace, Montjuïc) supported by the TRANSBIO SUDOE, a translational cooperation project dedicated to innovation in life sciences in South-West Europe. The Barcelona Emergence Forum contributed to bringing together Academics, Companies, Investment Entities, Technology Platforms and Technology Transfer Offices from Spain, France and Portugal to set up collaborative projects on Human Health & Agro-food Innovation. More information at: http://www.b2match.eu/emergenceforum2014
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System Biology Approaches to Personalized Medicine
© Anaxomics 2014
Teresa Sardon MSc, PhD Head of BU - Analytical Services
Member of eight EU 7th Framework Programme research consortia Finalist in 2011 Red Herring Top 100 Europe 4th place in IMPROVER Challenge 2012
Founded in 2007 – Private capital Based in Barcelona 20 Experts (Pharmacology, Physiology, Artificial Intelligence) Proprietary technology: Therapeutic Performance Mapping System (TPMS)
Company Profile
Academic Researchers Pharmaceutical companies Nutraceuticals Clinical Researchers CROs Cosmetics Biotechnology companies Venture Capital Veterinary Industry
© Anaxomics 2014
OUR CLIENTS:
ACHIEVEMENTS:
OUR GOAL: “Applying Systems Biology to Health & Life Science to provide solutions
to the most challenging biological and medical needs“
Systems Biology + data from different sources → Mathematical Models
Systems Biology
© Anaxomics 2014
Efficacy and safety assessment
Molecular and clinical model
Mechanism of action
Target discovery
Combination therapies
Drug repositioning – New indications
Biomarkers discovery
© Anaxomics 2014
Shared characteristics
Clinical data
Omics • Genomics • Proteomics • Transcriptomics • Metabolomics
…
+ Experimental data
From Systems Biology to Personalized Medicine
Cohort 1 Cohort 2
Responders Non-responders
© Anaxomics 2014
MoA
Biomarkers
Treatment Selection
Case Study: Treatment Responders and Non Responders
MoA Reversion
How do you get it?
© Anaxomics 2014
Consulting Services: Fee for Service
Partnership Agreements: -Service Platforms -Research Instituts -Other companies
CONTACT US: [email protected] [email protected] Thanks for your attention!
