1. Nolvadex TabletsNolvadex Tablets (Tamoxifen Citrate) is usedfor the treatment of breast cancer. It is alsoused to reduce breast cancer incidence inhigh risk women. The Swiss Pharmacy, Geneva Switzerland

2. Nolvadex TabletsChemical Structure The Swiss Pharmacy, Geneva Switzerland 3. Nolvadex TabletsIndicationsNolvadex Tablets are effective in the treatment ofmetastatic breast cancer in women and men.Adjuvant Treatment of Breast Cancer. Nolvadex isindicated for the treatment of node-positive breastcancer in postmenopausal women following totalmastectomy or segmental mastectomy, axillarydissection, and breast irradiation.In women with Ductal Carcinoma in Situ (DCIS),following breast surgery and radiation, Nolvadex isindicated to reduce the risk of invasive breastcancer. The Swiss Pharmacy, Geneva Switzerland 4. Nolvadex TabletsIndicationsNolvadex (Tamoxifen Citrate) is indicated toreduce the incidence of breast cancer inwomen at high risk for breast cancer.Tamoxifen is used to treat infertility in womenwith anovulatory disorders. Tamoxifen is usedto prevent estrogen related gynecomastia,resulting from elevated estrogenic levels.It is taken as a preventative measure in smalldoses, or used at the onset of any symptomse.g. nipple soreness/sensitivity. The Swiss Pharmacy, Geneva Switzerland 5. Nolvadex TabletsActive Pharmaceutical IngredientThe active pharmaceutical ingredient contained inNolvadex Tablets is Tamoxifen Citrate.Each 10 mg Nolvadex Tablet contains 15.2 mg ofTamoxifen Citrate which is equivalent to 10 mg oftamoxifen.Nolvadex (Tamoxifen Citrate) is a nonsteroidalantiestrogen for oral administration. The Swiss Pharmacy, Geneva Switzerland 6. Nolvadex TabletsHow Does it Work?Nolvadex Tablets contain theactive ingredient tamoxifen whichworks by blocking the actions ofoestrogen, a female sex hormone.It belongs to a group of medicinesknown as non-steroidal anti-oestrogens. The Swiss Pharmacy, Geneva Switzerland 7. Nolvadex TabletsRecommended Adult DosageSwallow the tablets with a glass of water atabout the same time each day. Nolvadextablets can be taken with or without food.Breast Cancer:For patients with breast cancer, therecommended daily dose of Nolvadex is 20mg to 40 mg. Dosages greater than 20 mgper day should be given in divided doses(morning and evening). The Swiss Pharmacy, Geneva Switzerland 8. Nolvadex TabletsRecommended Adult DosageDuctal Carcinoma in Situ (DCIS):The recommended dose is 20 mg of Nolvadexdaily for 5 years.Reduction in Breast Cancer Incidence in HighRisk Women:The recommended dose is 20 mg of Nolvadexdaily for 5 years.Infertility (Anovulatory Disorders):The recommended dosage of Nolvadex is 10mg to 40 mg per day which is administered indays 3 to 7 of a woman's cycle. The Swiss Pharmacy, Geneva Switzerland 9. Nolvadex TabletsContraindicationsNolvadex Tablets are contraindicated inpatients with a hypersensitivity toTamoxifen Citrate or other componentspresent in this medication.It is also contraindicated in patientsthat are pregnant. The Swiss Pharmacy, Geneva Switzerland 10. Nolvadex TabletsSide Effects of Nolvadex (Tamoxifen)In patients treated with Nolvadex Tablets formetastatic breast cancer, the most frequent sideeffect is hot flashes. Other side effects which areseen infrequently are hypercalcemia, peripheraledema, distaste for food, pruritus vulvae,depression, dizziness, light-headedness, headache,hair thinning and/or partial hair loss, and vaginaldryness.During the treatment of Adjuvant Breast Cancer themost common side effects were hot flashes, vaginaldischarge and irregular menses. Nolvadex(Tamoxifen Citrate) may cause dizziness, lightheadedness or blurred vision in some people. The Swiss Pharmacy, Geneva Switzerland 11. Nolvadex TabletsWarnings And PrecautionsHypercalcemia has been reported in some breastcancer patients with bone metastases within a fewweeks of starting treatment with Nolvadex.An increased incidence of uterine malignancies hasbeen reported in association with Nolvadextreatment.An increased incidence of endometrial changesincluding hyperplasia and polyps have been reportedin association with Nolvadex treatment.There is evidence of an increased incidence ofthromboembolic events, including deep veinthrombosis and pulmonary embolism, duringNolvadex therapy. The Swiss Pharmacy, Geneva Switzerland 12. Nolvadex TabletsWarnings And PrecautionsIn a trial using adjuvant Nolvadex 40 mg/day for 2-5years, 3 cases of liver cancer have been reported inthe Nolvadex-treated groupNolvadex has been associated with changes in liverenzyme levels, and on rare occasions, a spectrum ofmore severe liver abnormalities including fatty liver,cholestasis, hepatitis and hepatic necrosis. The Swiss Pharmacy, Geneva Switzerland 13. Nolvadex TabletsNolvadex Tablets manufacturedby Astra Zeneca UK Ltd.For more information click here The Swiss Pharmacy, Geneva Switzerland