Indian

By SOMNATH SURAI CHINA PHARMACEUTICAL UNIVERSITY

Objectives

• Introduction to Ayurveda• Historical background• kalmegh• Reported benefits• Reasons for caution• Current Research• Conclusions

WHAT IS THE AYURVEDA • Comprehensive system that places equal

emphasis on the body, mind and spirit, and it strives to restore the innate harmony of the individual

• Ayurveda is the combination of two Sanskrit words– “ayu” meaning long life– “ved” meaning knowledge– “Knowledge or science of life”

• Covers all medical fields• Diagnosis done by observation, touch, and

questioning• Four components to

disease management– Physician, Drug, Patient,

Attendant (such as a nurse)

Historical background of Ayurveda

 It is said in "Ayurvedavatarana" that Lord Brahma sung these life- giving slokas to other deities who would together relieve human race of severe suffering. Dhanvantari was one among those deities who propagated Ayurveda in the mortal sages; the elixir of life thus came to be known as the divine science of revelation .It equalizes the worth of deep perception, inner vision and realization with empirical observation. Ayurveda is hence, crowned as the "Mother of all healing". 

WHERE FROM AYURVEDA COMES?

Ayurveda was a divine system of medicine5000 BC to 4000 BCComes from Sanskrit writings of mythic-

religious hymns related to the civilization in Vedas

Rik veda refers to the cosmology known as Sankhya - base of Ayurveda & Yoga

Atharva veda – details about Ayurveda

WHY AYURVEDA COMES ON EARTH

PEOPLES START TO LIVE AGAINST NATURE

EAT AGAINST NATURE

BECOMES LAZY

WHO THOUGHT FOR AYURVEDA

ANICIENT SAINTS – STRESHED ABOUT DISEASES

MEETING ON HIMALYAS

DICIDE TO SENT MAHARISHI BHARDWAJ

SCHOOLS OF AYURVEDA

ATRYA

the school of physicians

DHANWANTRI

the school of surgeons

THREE MAIN TEXT BOOKS OF AYURVEDA

Caraka Samhita (approximately 1500 BC)

Ashtang Hridyam (approximately 500 AD)

Sushrut Samhita(approximately300 - 400AD)

The Five Elements and Modern Physics

• Space represents the Unified Field

• Air represents to Motion and Acceleration

• Fire represents Radiant Energy and Heat

• Water represents Cohesive Forces and Gravity

• Earth represents Mass

pancha mahavuta

AIMS OF AYURVEDA

TO ACHIEVE POSITIVE HEALTH FOR THE INDIVIDUAL.

PROTECTION OF THE MASSES.

ULTIMATE LIBERATION.

kalmegh

About

• Scientific Name: Andrographis Paniculata• English Name: Creat , Green Chirayta,

King of bitters.• Chinese name :Chuan Xin Lian • Common (Indian) Name:• Hindi: Kalmegh, Kiryat, Mahatit,• Family: Acanthaceae

Bile of the Earth

• A well known plant used in Ayurvedic Medicine - Kalamegha “dark cloud”

• Leaves and Stems used for medicinal Purposes• Used in the prevention and treatment of the

common cold• Anticancer activity• 28 species, A. Paniculata is most often used

medicinally

King of Bitters

• A small annual herb• Cultivated in India,Srilanka

,china and Southeastern Asia

• Species vary in height, 30 cm -110 cm tall• Grows in moist shady

places• Very bitter flavor

Background/History

• Influenza epidemic broke out at the end of WW1, killed more people than the war.

• Spread through North America, Europe, Asia, Brazil, and South Pacific

• India had a very high Death rate. 50 adults out of 1000 between ages of 20-40

• Andrographis was credited with halting influenza in India.

• Ayurveda practitioners have been using it since 1500 - 1800 BC

Chemistry

•Andrographolide is the major constituent extracted from whole plant •constituents are:•14-Deoxy-11-oxoandrographolide•Tetramethoxyflavone•Andrographine, Panicoline, Paniculide-A,•Paniculide-B,•Paniculide-C

Traditional medicine

• Since ancient times, A. paniculata has been used in traditional Siddha and Ayurvedic systems of medicine as well as in tribal medicine in India. This plant is a major ingredient of the polyherbal formulation by the name "Nilavembu kudineer choornam" in Siddha medicine.

• According to the Mayo Clinic Book of Alternative Medicine, "A specific product may shorten the duration and lessen the symptoms of common cold." It also says, "Pregnant women shouldn't use andrographis because it could terminate pregnancy."

Medical formulation

Other Uses

• Anti-diarrhea• treatment upper respiratory tract infections. • Anti-inflammatory• Anti-bacterial• Anti-viral• Hepatoprotective (protects the liver)

Anti-inflammatory & anti-cancer

• NF-kB regulates the genes of cells to keep proliferating and protects them from conditions that cause the cells to die.

• Cancer cells secrete factors that activate NF-kB to become active.

• Andrographis P inhibits NF-kB becoming active.

Controlling Glucose levels

• Rats were given A. Paniculata orally• Studies have shown activation of alpha 1A

adrenoceptors in the adrenal medulla might enhance the secretion of beta-endorphins from the rat adrenal gland.

• A.Paniculata can activate alpha 1A adrenoceptors leading to an increase glucose uptake resulting in a reduction of plasma glucose by 23%.

Influenza study continued

• The herbal group experienced a shorter duration 6-7 days

• The control group experienced a longer duration 9-10

• A second phase of the trial had 31 people taking the herbal treatment while 35 were in the control group.

• Comparable results were found.

Side effects/contraindications

• Loss of appetite• Diarrhea• Vomiting• Rash• Headache• Fatigue

contraindications

• Blood pressure medications – A. Paniculata can lower blood pressure

• Immunosuppressant drugs– A. Paniculata boosts immune functionBlood clotting medication

Conclusion

Scientific studies support the effectiveness of Andrographis Paniculata in shortening the duration of colds and flues.

Inhibits the proliferation of cancer cells by inhibiting NF-kB activation.

Reduces plasma glucose levels in rats.It has been used safely for centuries by Ayurveda

practitioners to treat a variety of aliments.The next time you have a cold, reach for the

Andrographis Paniculata.