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Hepatic osteodystrophy.
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Hepatic osteodystrophy:Dr.Mohammad Shaikhani.
MBChB/CABM/FRCP
Prevalence.Prevalence.
ContentsContents
Introduction:Introduction:
Pathophysiology:Pathophysiology:
Risk factors.Risk factors.
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55 Key points..Key points..
• Osteoporosis is a common complication of many types of liver disease.
• The mechanisms of bone loss differ between different types of liver disease.
IntroductionIntroduction
• Osteoporosis is a common complication of chronic liver disease.
• Like senile osteoporosis, liver-diseaseassociated osteoporosis results from an imbalance between bone formation& resorption that leads to a net decrease in bone mass.
• The factors responsible for reduced bone formation and/or increased bone resorption in liver-disease-associated osteoporosis remain incompletely understood.
• Advances shed some light on the potential pathogenic mechanisms involved in this process.
IntroductionIntroduction
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