Cinnamon inFUSED Products

Making Cinnamon inFUSED Wearpart 1 - History & Uses

part 2 - Scientific Research

www.aromanticwear.com

This presentation is for information purposes only

and should not be interpreted as specific

medical advice.

Centuries of Cinnamon

Illustration of Powdered Saigon CinnamonSayre: A Manual of organic materia medica and pharmacognosy

Courtesy of http://www.archive.org/

http://www.archive.org/

Why Cinnamon

aromaticantibacterial

anti-inflammatory properties

stimulates blood circulation

natural

In the Quảng Nam Province of Vietnam live some of the

most vibrant cinnamon trees in the world, a land

with a centruies old tradition of growing & harvesting the regions

prized cinnamon

Cinnamomum loureirii has thrived in the central highlands of Vietnam for centuries. Its cinnamon trees are said to contain the highest percent of the medicinal

component of cinnamon found in its oil -

Baby Cinnamon Trees - Bloom

Farmers tend the entire life cycle until final harvest and grading

The medicinal componet of Cinnamon is derived

from its Oil

Which is derived from the leaves, bark and

sometimes roots

After sunlight curing, cinnamon tree parts are left intact or combined with

other raw materials

drying cinnamon bark

Traditional & Modern Fabrication

PERSONAL WEAR

PERSONAL CARE

products are made from all parts of the treeALL PARTS OF THE CINNAMON TREE ARE USED

~ Part 2 next . . .

End of Part 1 - Thank You !

PART 2

Scientific Research

For complete references of the Monograph of Cinnamon (Cinnamomum spp.) and research,

please reference The Natural Standard www.naturalstandard.com

or the for the brief version www.aromanticwear.com

The Research in this document is derived from The Natural Standard www.naturalstandard.com

Natural Standard MonographCinnamon (Cinnamomum spp.)

Copyright © 2011Commercial Distribution Prohibited

~This monograph is intended informational purposes only,

and should not be interpreted as specific medical advice.

You should consult with a qualified healthcare provider before

making decisions about therapies and/or health conditions.

http://www.naturalstandard.com/

r e l a t e d

t e r m s

�1-methoxy-4-(1-propenyl) benzene (transanethole), 2-substituted 4-(3H)-

quinazolinones,3-phenyl-2-propen-l-ol (cinnamyl alcohol), 5,7,3',4'-tetrahydroxyflavan-3,4-diol, aitokaneli (Finnish), äkta kanel (Swedish), akupatri (Telugu), albero della cannella (Italian),

alpha-amyl cinnamaldehyde, American cinnamon, Batavia cassia, Batavia cinnamon, breyne, canela (Portuguese, Spanish), canela de la China (Portuguese,

Spanish), caneleiro (Portuguese), canelero chino (Spanish), canelero de Ceilán (Spanish), canelheira da India (Portuguese-Brazil), cannelier de

Chine (French), cannella (Italian), cannella del Ceylan (Italian), cannella della Cina (Italian), cannelle (French), cannelle de Ceylan (French), cannelle de Chine (French),

cannelle de Cochinchine (French), cannellier casse (French), cannellier de Ceylan (French), cannellier de Chine (French), cassia(English, Italian), cássia (Portuguese), cássia-aromática (Portuguese), cassia bark,cassia-bark tree, cassia cinnamon, cassia

lignea, cassia rou gui, catechins, cây que(Vietnamese), Ceylon cinnamon, ceyloni fahéj (Hungarian), ceyloninkaneli (Finnish),ceylonkanel (Swedish),

ceylonski cimet (Croatian), Ceylonzimt (German),

Cinnamon (Cinnamomum spp.)

r e l a t e d

t e r m s

�Cinnamon (Cinnamomum spp.)

Ceylonzimtbaum (German), chadana (Sanskrit), chek tum phka loeng (Khmer), Chinazimt (German), Chinese-cassia, Chinese cinnamon, Chinesischer Zimt (German),

Chinesischer Zimtbaum (German), cin tarçını (Turkish), cinnamal, cinnamaldehyde, cinnamate, cinnamic acid, cinnamic aldehyde, cinnamom-dhal chini Cinnamomi cassiae,

Cinnamomi cassiae cortex, Cinnamomi ceylanici cortex, Cinnamomi cortex,

Cinnamomi flos, Cinnamomi osmophloeum, Cinnamomi ramulus,

Cinnamomom, Cinnamomum aromaticum, Cinnamomum aromaticum Nees, Cinnamomum burmannii, Cinnamomum cassia, Cinnamomum cassia Blume,

Cinnamomum cassia J. Presl, Cinnamomum cinnamon,Cinnamomum loureiroi, Cinnamomum mairei Levl., Cinnamomum migao,

Cinnamomum obtusifolium, Cinnamomum osmophloeum clones (A and B), Cinnamomum osmophloeum Kaneh., Cinnamomum sieboldii, Cinnamomum Cinnamomum

osmophloeum Kaneh., Cinnamomum sieboldii, Cinnamomum sieboldii Meissn.,

Cinnamomum tamala,

Background Cinnamon has been used as a spice in several cultures for centuries.

It was traditionally used to relieve stomach pain and gas; it is still used for these conditions today. The bark of two cinnamon species (Cinnamomum zeylanicum and

Cinnamomum cassia) is used as a spice (cinnamon bark)

There is a lack of scientific information to support the use of cinnamon for any condition. However, laboratory studies suggest that cinnamon may be useful in the

treatment of diabetes (type 2) due to its blood sugar-lowering effects.

Furthermore, cinnamon and its constituents may have anti-inflammatory, antibacterial, antifungal,

and antioxidant properties, and it may prove effective in the supportivetreatment of conditions such as cancer or

severe virus infections.

Uses Based scientific on evidence

These uses have been tested in humans or animals.

Safety and effectiveness have not always been

proven. Some of these conditions are potentially

serious, and should be evaluated by a qualified

healthcare provider.


Angina (chest pain)The use of cinnamon for bacterial angina has been reviewed. However, well- designed trials are needed before a firm conclusion can be made.

Antioxidant Based human study, a dried aqueous extract of cinnamon (Cinnulin PF®) may improve the antioxidant status of overweight or obese individuals with impaired fasting glucose.

More well-designed trials are needed before a firm conclusion can be made.


Cinnamon has been granted GRAS (Generally Recognized as Safe) status as a food additive by the U.S.

Food and Drug Administration (FDA).

GRAS substances are considered safe by the experts and not restricted, as is the case with other food additives.


Allergic rhinitisPreliminary evidence suggests that cinnamon may have antiallergic properties. Based on human study, a combination product including Cinnamomum zeylanicum, Malpighia glabra, and Bidens pilosa has

demonstrated reduced allergic nasal symptoms in patients with allergic rhinitis. More well-designed trials are needed before a firm conclusion

can be made.


Bacterial InfectionPreliminary study suggests that cinnamon may treat bacterial infections

including chronic salmonellosis. However, well-designed trials are needed before a firm conclusion can be made.

CandidiasisPreliminary evidence suggests that cinnamon may have activity agains

Candida. However, well-designed trials are needed before a firm conclusion can be made.


DiabetesBased on human study, cinnamon has been used to control blood sugar;

however, results have been mixed in other studies. Further study is needed before a firm conclusion may be made.

Eye disordersPreliminary data suggests that a combination herbal eye drop preparation

(OphthaCare) may be useful in the treatment of various ophthalmic disorders including: conjunctivitis, conjunctival xerosis (dry eye), acute dacryocystitis, degenerative conditions (pterygium or pinguecula), and

disorders in postoperative cataract patients. However, well-designed trials are needed before a firm conclusion can be made.


Helicobacter pylori infection

Preliminary evidence suggests that cinnamon extracts may be effective against Helicobacter pylori. Based on human study, cinnamon extract

was ineffective in ridding of H. pylori. However, the combination of cinnamon with other antimicrobials, or cinnamon extract at a higher

concentration, may prove useful. Further well-designed trials are needed before a firm conclusion can be made.


Insect repellantPreliminary evidence suggests that cassia oil (Cinnamomum cassia) may reduce dust mites. Based on human study, cinnamon may be useful as a

mosquito repellant. However, well-designed trials are needed before a firm conclusion can be made

Lung cancerPreliminary study suggests that cinnamon may be useful in the treatment of

lung cancer. However, well-designed trials are needed before a firm conclusion can be made.


Metabolic syndrome(coronary heart disease)

Preliminary study suggests that cinnamon may be useful in the treatment of features of metabolic syndrome in prediabetic subjects. However, well-designed trials are needed before a

firm conclusion can be made.

Uses based on tradition or theory

The below uses are based on tradition or scientific theories. They often have not been thoroughly tested in humans, and safety and

effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a

qualified healthcare provider.


Abdominal pain, abortifacient (induces abortion), abscess, acaricidal (kills mites), acne, Alzheimer’s disease, analgesic (pain reliever),

anesthetic, anthelmintic (expels parasitic worms), anticoagulant (stops blood from clotting), antidepressant, anti-inflammatory, antimutagenic,

antiparasitic, antiplatelet (interferes with the blood ability to clot), antipyretic (reduces fever), antiseptic, antispasmodic (suppresses spasms), antiviral, arrhythmia, arthritis, asthma, benign prostatic

hyperplasia, bloating, blood purification, bronchitis, chronic bronchitis, chronic diarrhea, cognitive function, colds/flu, colic, cough,


Cystitis (inflammation of urinary bladder), dental caries (cavities), deodorant, dermatitis (inflammation of the skin),

diarrhea, digestive aid, digestive disorders, diuretic (increases urination), dyspepsia (indigestion), eczema, emmenagogue

(stimulates menstruation), flavoring, food poisoning, food preservation, food uses, gastric ulcer, gastritis (stomach lining

inflammation), gout, gum disease, gynecologic disorders, HIV/AIDS, hypercholesterolemia (high cholesterol),

hypertension (high blood pressure), hyperthyroid (overactive thyroid gland), immunostimulation (stimulates the immune

system),


Inflammatory conditions, kidney disorders, lice, liver disease, long- term debility, loss of appetite, memory loss, movement disorders, muscle aches, nausea, neuralgia (nerve pain), neuroprotective,

premature ejaculation, respiratory tract infection, rheumatoid arthritis, sciatica, sinusitis, skin conditions, snake repellent, sore

throat, spermicide, toothache, tumors, urethritis (inflammation of the urethra), urinary disorders, viral infections, weight gain, wound

healing.

The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs

and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the

same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a

qualified healthcare provider before starting therapy.

DOSING

Adults (over 18 years old)There are no proven effective medicinal doses for cinnamon. Cinnamon is

likely safe when taken by mouth short-term (up to six weeks) in dosages up to 6 grams daily and in amounts commonly found in foods.

~As an antioxidant, capsules containing 250 milligrams of cinnamon extract

(Cinnulin PF®) twice daily for 12 weeks. For candidiasis, eight lozenges of a commercially available cinnamon candy were taken daily for one week; for

oral candidiasis, a solution, made by cooking 250 grams of cinnamon in 2000 milliliters of water on medium heat until there

was 500 milliliters of solution (solution defined as 50% cinnamon solution) has been used. This solution has been gargled 4-6 times a day and each

time with 20-30 milliliters of the solution.

DOSING

For diabetes, various doses of cinnamon (capsules, powder, extract) have been studied. 1-6 grams of cinnamon daily has been used for up

to 90 days. For Helicobacter pylori infection, 80 milligrams of cinnamon extract daily was used for four weeks. For metabolic syndrome, 500 milligrams of a water-soluble cinnamon extract,

Cinnulin PF®, is recommended by the manufacturer.As an insect repellant, variousdoses have been studied including a

single application of cream containing 5% (w/w) cassia oil (containing 5 grams of cassia oil) for up to 120 minutes.

DOSING

SAFETYChildren (under 18 years old)

There is no proven safe or effective medicinal dose of cinnamon in children.

--------The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or

safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider

before starting a newtherapy. Consult a healthcare provider immediately if you experience

side effects.

Allergies

Avoid in individuals with a

known allergy or

hypersensitivity to cinnamon,its constituents,

members of the Lauraceae family,or Balsam of Peru.

Side Effects and Warnings

Cinnamon is likely safe when taken by mouth short-term.As with any spice or drug, cinnamon can be contaminated by

microorganisms during storage. Caution is advised when choosing cinnamon products.

Some people may be allergic or sensitive to cinnamon, but this is rare. Skin rash and inflammation, mouth sores, tongue inflammation, gum

disease, acne, mouth lesions, andinflammation of the lips have been noted after applying cinnamon (e.g. cinnamon oils, flavored chewing-gums, mints, or toothpastes) on the

mouth or face.


Cinnamaldehyde (the chemical compound that gives cinnamon its spice) may cause swelling of the lips,mouth tissue, and the

face, hives, skin rash, and mouth sores.

Prolonged exposure tocinnamon-flavored gum may cause cancer. Asthma and other breathing difficulties were seen in spice-factory workers. Large amounts of cinnamon may be

toxic to the liver due to possible coumarin content.

Caution is advised when using other medications that may be hepatotoxic (toxic to the liver).


Although not well studied in humans, large amounts of cinnamon (more than those found in foods) should be avoided in pregnant

women due to possible abortion inducing effects. Use cautiously in patients taking drugs that affect the function of the immune system. Use cautiously in patients taking drugs that lower

cholesterol.Although not well studied in humans, cinnamon bark may cause decrease in platelet counts in the blood after long-term use. Use cautiously in patients taking drugs, herbs, or supplements broken down by the liver. Use cautiously in patients with liver damage.


Cinnamon may lower blood sugar levels.Use cautiously in patients with diabetes or low

blood sugar (hypoglycemia).Cinnamon may enhance the effect of

antibiotics.Cinnamon may interact with cardiovascular (heart) agents, due to its several effects on blood and the cardiovascular system

(e.g. antiarrhythmic properties).Use cautiously in people with heart conditions


Pregnancy & BreastfeedingCinnamon is not recommended in medicinal amounts in pregnant or breastfeeding women due to a lack of available scientific evidence Although not well studied in humans, large amounts of cinnamon (more than those found in foods) should be avoided in pregnant

women due to possible abortion inducing effects.Cinnamon may act as a spermicide, thereby preventing pregnancy

by killing sperm;however, it is not recommended as a form of birth control.

INTERACTIONS

Most herbs and supplements have not been thoroughly tested for interactions with other herbs, supplements, drugs, or

foods. The interactions listed below are based on reports in scientific publications, laboratory experiments, or traditional use. You should always read product labels. If you have a

medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare

provider before starting a new therapy.

INTERACTIONS with Drugs

Cinnamon may have antibacterial activity. Use cautiously with antibiotic medications, due to possible additive effects. Cinnamon may lower blood sugar levels. Caution is

advised when using medications that may also lower blood sugar. Patients taking drugs for diabetes by mouth or insulin should be monitored closely by a qualified healthcare

professional, including a pharmacist. Medication adjustments may be necessary.Cinnamon may increase the risk of bleeding when taken with drugs that increase the riskof bleeding. Some examples include aspirin, anticoagulants (“blood

thinners”) such aswarfarin (Coumadin®) or heparin, anti-platelet drugs such as clopidogrel (Plavix®), and non-steroidal anti-inflammatory drugs (NSAIDS) such as

ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®). The antifungal properties of cinnamon may enhance the effect of commonly used antifungals.

Cinnamon may have antispasmodic effects. Use cautiously if taking other antispasmodics. Cinnamon bark extract may have antiviral effects. Use cautiously if taking antiviral medications, due to possible additive effects. Cinnamon may affect

heart rate and thus may interact with heart rate regulating agents.Caution is advised in people taking agents for heart conditions.

INTERACTIONS with Drugs

Cinnamon may interfere with the way the body processes certain drugs using the liver’s “cytochrome P450” enzyme system. As a result, the levels of drugs in the blood may be altered.Cinnamon may have effects on the immune system. Use

cautiously with other agents that alter the immune system. Consult with a qualified healthcare professional, including a pharmacist, to check for interactions.Cinnamon

may lower cholesterol. Caution is advised when using medications that may also lower cholesterol.Cinnamon may lower blood pressure. Caution is advised when using medications that may also lower blood pressure. Cinnamon may be toxic to the liver in large amounts due to possible coumarin content. Caution is advised

when using other medications that may be hepatotoxic (toxic to the liver). Cinnamon may interact with alcohol, drugs that are used to treat Alzheimer’s disease,

analgesics (pain relievers), drugs that decrease inflammation, anti-cancer drugs, anti-obesity drugs, aspirin, dexamethasone, drugs that affect GABA, estrogen,

indomethacin, sympathomimetics, terfenadine, or tetracycline.

Interactions with Herbs & Dietary Supplements

Cinnamon may have antibacterial activity.Use cautiously with antibacterial herbs and supplements, due tpossible additive effects

Cinnamon may lower blood sugar levels. Caution is advised in patients with diabetes or hypoglycemia, and in those taking herbs or supplements that affect blood sugar. Serum glucose levels may need to be monitored by a qualified healthcare professional, including a pharmacist, and doses

may need adjustment.Cinnamon may increase the risk of bleeding when taken with herbs and supplements that are believed to increase the risk of bleeding. Multiple cases of bleeding have been reported with the use of

Ginkgo biloba, and fewer cases with garlic and saw palmetto.The antifungal properties of cinnamon may enhance the effects of commonly used

antifungals. Cinnamon bark has been shown to contain very high concentrations of antioxidants.


Use cautiously with herbs and supplements that are taken for their antioxidant effects, due to possible additive effects.Cinnamon may have antispasmodic effects.

Use cautiously with other antispasmodics.Cinnamomum cassia bark extract may have antiviral effects. Use cautiously with antiviral herbs or supplements, due to

possible additive effects. Cinnamon may affect heart rate and thus may interact with heart rate regulating agents.People taking herbs or supplements that alter heart rate

should use cinnamon with caution.Cinnamon may interfere with the way the body processes certain herbs or supplements using the liver’s “cytochrome P450” enzyme

system. As a result, the levels of other herbsor supplements in the body may be altered.Cinnamon may have effects on the immune system; use cautiously with

herbs and supplements with similar effects.Cinnamon may lower cholesterol; use cautiously with herbs and supplements with similar effectsCinnamon may lower blood pressure. Caution is advised when using other herbs or supplements that may also lower blood pressure.Cinnamon may be

toxic to the liver in large amounts due to possible coumarin content.


Caution is advised when using other herbs or supplements that may be hepatotoxic (toxic to the liver).

Cinnamon may interact with herbs or supplements that are used to treat Alzheimer’sdisease, analgesics (pain relievers),

herbs or supplements that decrease inflammation,anti-cancer herbs or supplements, anti-obesity herbs or

supplements, herbs or supplements that affect GABA, herbs or supplements with hormonal effects, clove, ephedra, or

artemisia.

References

This information is based on a systematic review of scientific literature, and was peer- reviewed and edited by contributors to

the Natural Standard Research Collaboration

www.naturalstandard.com

Please see monograph for full references*

http://www.naturalstandard.com/

Health & Medicine

Cinnamon inFUSED Products