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Humanity has released approximately 100,000 new chemical compounds into the environment, mostly in the past 100 years. Compounds our bodies have never seen before and weren't designed to deal with. In this talk we will discuss some of the common environmental toxins and how they have been shown to be harmful to human health. We will also discuss: testing methods for quantifying toxicity, how the body detoxifies (the seven organs involved) and provide simple methods audience members can take to reduce their toxic burden, as well as briefly discuss more intensive, physician practices for detoxification for people who need it.
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“Everybody needs beauty as well as bread, places to play and pray in, where nature may
heal and give strength to body and soul.” John Muir
BACON“Everybody needs beauty as well as bread,
places to play and pray in, where nature may heal and give strength to body and soul.”
NOT John Muir
It Ain't Your Great-Great Grandparents
World: Environmental
Toxicity and Health
Dr. Tim Gerstmar
“I think that people who use cleanses may have had rough anal periods (see Freud, Sigmund)...Cleanses and...colonics have about as much medical merit...as the acts of penance done by monks who’d walk across Europe and hit themselves on the back to purge themselves of the plague.” --Michael Gershon, MD
OVERVIEW
1. Toxicity - what is it? Is it real?
2. Evolutionary context
3. Health effects – example: thyroid
4. Vulnerability
5. Detox – what is it? How to do it
6. Q&A – Fingers crossed
What is Toxicity?
Toxin – substance that interferes with normal metabolic function
Metabolic toxicity
Endotoxemia
Xenotoxicity
Evolutionary discordance
Evolutionary discordance
Evolutionary exposure
Evolutionary exposure
Evolutionary exposure
Evolutionary exposure
Evolutionary exposure
Evolutionary exposure
Current exposure
China
China
Huai river - 1973-2006
Cancer-related deaths >2x
Liver cancer >5x
“The data confirms a geographical overlap in the increased cancer death rate and water pollution…
and a temporal lag - a high occurrence of cancer following a surge in pollution - for about a decade...”
Ruled out other known risk factors – smoking, diet, hepatitis B
Current exposure
Body Burden Studies
•9 adults
•Tested for 214 chemicals; Found 171
•Average 91 per person with 58 carcinogens
First Round - 2003
Body Burden Studies
•55 adults
•Tested for 528 chemicals; Found 432
•Average 156 per person with 23 carcinogens
Second Round - 2005
Body Burden Studies
•10 newborns•Found 287 chemicals
•180 cause cancer in humans or animals•217 are toxic to the brain and nervous system•208 cause birth defects or abnormal development in animals
Newborns- 2004
Scorecard.org – Zip 30303
In 2002, Fulton county ranked among the dirtiest/worst 10% of all counties in the U.S. in terms of air releases of recognized carcinogens.
1 FORD ATLANTA ASSEMBLY PLANT HAPEVILLE 788,037 lbs
2 OWENS CORNING FAIRBURN 455,505
3 PPG ARCHITECTURAL FINISHES EAST POINT 139,424
4 KRAFT FOODS ATLANTA PLANT ATLANTA 43,579
5 POREX TECHS FAIRBURN 41,228
Scorecard.org – Zip 30303
1 AMMONIA 428,389 lbs
2 XYLENE (MIXED ISOMERS) 248,797
3 GLYCOL ETHERS 168,253
4 N-BUTYL ALCOHOL 152,056
5 METHYL ISOBUTYL KETONE 129,791
6 TOLUENE 103,007
7 FORMALDEHYDE 100,389
8 1,2,4-TRIMETHYLBENZENE 68,175
9 METHYL ETHYL KETONE 64,175
10 ETHYLBENZENE 53,326
Types of Toxic Exposures
1. Acute
2. Chronic – single agent, mixed agents
3. Contributing
Acute Exposure
Chronic exposure
Chronic exposure
65yo male
Peripheral neuropathy (of trunk & arms)
Chloracne
Insulin-dependent diabetes
BMI 33
Fasting glucose 306
Chronic exposure
65yo male 67yo malePeripheral neuropathy (of trunk & arms)
Chloracne
Insulin-dependent diabetes
BMI 33 27 (-40lbs)
Fasting glucose 306 95
Chronic exposure
Contributing exposure
What do toxins do?
-Endocrine disruption
-Carcinogens or growth disruptors
-Immune disruptors
-Neurotoxins
-Mitochondrial poisons
Health risks
Hormone disruptionThyroid Trouble
1. Nutrient deficiencies
2. Autoimmunity (~50% have other AI)
3. Neurological & other hormonal dysfunctions
4. Toxicity
Thyroid – the parts
Thyroid – how it's supposed to work
Thyroid – how it's supposed to work
Thyroid – how it's supposed to work
Thyroid – how it's supposed to work
Thyroid & Environmental toxicity
Thyroid & Environmental toxicity
Thyroid & Environmental toxicity
Thyroid & Environmental toxicity
Thyroid & Environmental toxicity
Thyroid & Environmental toxicity
Thyroid & Environmental toxicity
Thyroid & Environmental toxicity
Thyroid & Environmental toxicity
Is Xenotoxicity a concern?
Spectrum of Sensitivity
Multiple “Cast Iron” Chemical Sensitivity
Genetics of Detox
Genetics of Detox
Genetics of Detox
Functional Detox Impairment
Understanding Detox
Process NOT tools
What is detoxification?
Inactivation of a toxic substance
1. Mobilization
2. Inactivation
3. Excretion
DetoxificationWhat goes in
What comes out
The body
DetoxificationWhat goes in
What comes out
The bodyBody burden = what
stays insideBiotransformation
(Detox)
Mobilization
Inactivation
EnergyNutrients (Cofactors)
Excretion
Excretion
DESIGN FLAW!!!Enterohepatic recirculation
DESIGN FLAW
DESIGN FLAW=
EVOLUTIONARYDISCORDANCE
Do we need to augment detox?
Acutely – “Detox or die”
Chronic - Detox to resolve health problems
Contributing – evolutionary mismatch
Augment detox?
Rational Detoxification
DetoxificationWhat goes in
What comes out
The body
DetoxificationWhat goes in
What comes out
The bodyBody burden = what
stays insideBiotransformation
(Detox)
What goes in
Reduce Exposure
Testing your water
Testing your water
Reduce ExposureCosmetics
Household chemicals Lawn Chemicals
Buildings
Biotransformation
Biotransformation / Detox
1. Energy2. Nutrients / Cofactors
Herbs & Phytochemicals
Supplemental Precursors
Supplemental glutathione
Juicing?
What comes out
Making poop
Avoid constipation
DESIGN FLAW!!!Enterohepatic recirculation
Increasing bile excretion
Enemas and Colonics
Using the skin
Putting it together
DetoxificationWhat goes in
What comes out
The body
DetoxificationWhat goes in
What comes out
The bodyBody burden = what
stays insideBiotransformation
(Detox)
DetoxificationWhat goes in
What comes out
The body
DetoxificationWhat goes in
What comes out
The bodyBody burden = what
stays insideBiotransformation
(Detox)
DetoxificationWhat goes in
What comes out
The body
DetoxificationWhat goes in
What comes out
The bodyBody burden = what
stays insideBiotransformation
(Detox)
DetoxificationWhat goes in
What comes out
The body
DetoxificationWhat goes in
What comes out
The bodyBody burden = what
stays insideBiotransformation
(Detox)
DetoxificationWhat goes in
What comes out
The body
DetoxificationWhat goes in
What comes out
The bodyBody burden = what
stays insideBiotransformation
(Detox)
Putting it together
1. Limit exposure (reduce toxicity in)
Putting it together
1. Limit exposure (reduce toxicity in)
2. Nutrient dense diet w/ protein (detox)
3. Drink water (detox)
4. Supplemental nutrients & herbs (detox)
Putting it together
1. Limit exposure (reduce toxicity in)
2. Nutrient dense diet w/ protein (detox)
3. Drink water (detox)
4. Supplemental nutrients & herbs (detox)
5. Pee & Poop regularly (excretion)
6. Defeat enterohepatic recirculation (excretion)
“Aggressive” detox
1. Genetic testing
1. Genetic testing2. Functional testing
1. Genetic testing2. Functional testing3. Direct measurement of various toxins
Toxicity hurts
Sensible detox can help
You can't hide!
Rational Detox
“I think that people who dismiss cleanses & environmental toxicity without actually researching or understanding the topic may have had rough anal periods (see Freud, Sigmund)...Rationally used cleanses have medical merit, and those who deny it are still living in the medical dark ages...”
--Tim Gerstmar, ND
Dr. Tim Gerstmar
www.aspirenaturalhealth.comwww.facebook.com/AspireNaturalHealth@DrTimGerstmarND
