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9 Ways S Are you eating too many grains—can lead to ins Let us show you how to fin © 2013, Jeanne Evidence-based nutrition co Sugar Impact carbs? Sweets and starches— sulin resistance, which impact nd the right amount of carbs fo e M. Wallace, PhD, CNC • www.Nutritiona onsulting for cancer patients and oncolog ts Cancer —even “healthy” whole— ts cancer several ways. or your body!s metabolism. al-Solutions.net gists worldwide since 1997. Promotes ANGIOGENESIS, new blood vessels that fuel tumor growth and progression Stimulates MITOSIS, the division of a cell into daughter cells Increases insulin- like growth factor (IGF-1), a potent growth factor that allows cancer cells to EVADE APOPTOSIS (cell death) Exp Diabetes Res, 2012:789174. • Am J Pathol, 2006 Nov;169(5):1505-22. • Clin Cancer Res 2012;18(20):5585-94. Drives oxidation and increases DNA DAMAGE, which can stimulate cancer cell mutation and more aggressive behavior 1 4 Increases IL-6 and fans the fires of INFLAMMATION, a known tumor promoter INHIBITS IMMUNE FUNCTION 3 Stimulates synthesis of super- antioxidant GLUTATHIONE inside cancer cells, permitting them to escape the cytotoxic effects of chemotherapy and radiation treatments 6 7 8 Drives up circulating ESTROGEN levels 2 Boosts leptin, which stimulates CELL MIGRATION, and cancer spread (called metastasis) 5 9

9 Ways Sugar Impacts Cancer • Jeanne M. Wallace, PhD, CNC

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CARBS & CANCER: Are muffins, cookies or candies available in your oncologists office? Did your doctor tell you to eat milkshakes or sweets to help you maintain your weight? If you switched to whole-grain breads, cereals and pastas when you were diagnosed, are you still at risk? Use this handy infographic to educate yourself and others about the role of insulin resistance in fueling cancer growth and progression. Let's get the word out about the science linking carbs and cancer! Please share.

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Page 1: 9 Ways Sugar Impacts Cancer • Jeanne M. Wallace, PhD, CNC

9 Ways Sugar Impacts Cancer Are you eating too many carbs? Sweets and starches—even “healthy” whole—

grains—can lead to insulin resistance, which impacts cancer several ways.

Let us show you how to find the right amount of carbs for your body!s metabolism.

© 2013, Jeanne M. Wallace, PhD, CNC • www.Nutritional-Solutions.net

Evidence-based nutrition consulting for cancer patients and oncologists worldwide since 1997.

9 Ways Sugar Impacts Cancer Are you eating too many carbs? Sweets and starches—even “healthy” whole—

grains—can lead to insulin resistance, which impacts cancer several ways.

Let us show you how to find the right amount of carbs for your body!s metabolism.

© 2013, Jeanne M. Wallace, PhD, CNC • www.Nutritional-Solutions.net

Evidence-based nutrition consulting for cancer patients and oncologists worldwide since 1997.

9 Ways Sugar Impacts Cancer Are you eating too many carbs? Sweets and starches—even “healthy” whole—

grains—can lead to insulin resistance, which impacts cancer several ways.

Let us show you how to find the right amount of carbs for your body!s metabolism.

© 2013, Jeanne M. Wallace, PhD, CNC • www.Nutritional-Solutions.net

Evidence-based nutrition consulting for cancer patients and oncologists worldwide since 1997.

Promotes ANGIOGENESIS, new blood vessels that fuel

tumor growth and progression

Stimulates MITOSIS,the division of a cell into

daughter cells Increases insulin-

like growth factor (IGF-1), a

potent growth factor that

allows cancer cells to EVADE

APOPTOSIS (cell death)

Exp Diabetes Res, 2012:789174. •!Am J Pathol, 2006 Nov;169(5):1505-22. • Clin Cancer Res 2012;18(20):5585-94.

Drives oxidation and increases DNA DAMAGE, which can stimulate cancer cell mutation and more aggressive behavior

1 4

Increases IL-6 and fans the fires of

INFLAMMATION, a known tumor

promoter

INHIBITS IMMUNE

FUNCTION

3

Stimulates synthesis of super-

antioxidant GLUTATHIONE

inside cancer cells, permitting them to escape the cytotoxic

effects of chemotherapy and

radiation treatments

6

7

8

Drives up

circulating

ESTROGEN

levels

2

Boosts leptin, which stimulates CELL MIGRATION, and cancer

spread (called metastasis)

5

9