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Presentasjon av Det helsevitenskapelige fakultet, Universitetet i Tromsø. Inneholder utfyllende informasjon om noen utvalgte forskningsprosjekter (bl a Tromsøundersøkelsen, Kvinner og kreft, Telemedisin)
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A Short Introduction to Tromsø,the University of Tromsøand the Faculty of Health Sciences
On Top
of the
High North
Climate change
East Meets West
The Demand for Oil & Gas
Unspoiled Nature
Clean Food
A Cure for Cancer?
Tromsø in a Nutshell
Situated at 69°40′58″N 18°56′34″E
Founded 1794
Nicknames:
• “Paris of the North”
• “Gateway to the Arctic”
Population:
• 67.000 (urban area)
• The 8th largest city in Norway
Area 2.558 km2
• The largest urban municipality of Norway
• 40 .000 m2 per person
The University of Tromsø
• A classical university with a wide range of subjects taught.
• Merged with the Tromsø University college 1.1.2009
• 9.000 students, whereof 10% from abroad
• 2.800 staff• 2,1 billion NOK• More than 300 programs• Centers of Excellence,
Innovation, Peace andConflict Transformation,Sami studies, Tele-medicine, Women research,Biotechnology, Traditional Medicine etc.
• The University of Tromsø aims to be an academic institution of high international standing and with a special commitment to developing the North, combining quality and relevance, cutting-edge research and a wide range of educational opportunities
• The University of Tromsø aims to be at the international forefront in research and education pertaining to the Northern region.
• Particular emphasis shall be given to research in fields where the university has a comparative advantage due to its geographical location.
Aims & Commitments
Faculty of Health Sciences
This is where education, research and dissemination takes place within the fields of Psychology Biology Community medicine Clinical medicine Pharmacy DentistryAnd a host of health-related subjects, which
are normally University College subjects.
This comprehensive academic activity at our faculty is completely unique in a Norwegian context.
Faculty of Health Sciences
Education Medicine, dentistry,
pharmacy, psychology, nurses, bioengineers, radio charts, physiotherapists, ergo therapists, dental hygiene, public health nurses, midwifes
• Collaboration with hospitals and primary health care
Masters in biomedicine/telemedicine
Largest of faculties 7 departments 970 employees 3000 students
• 300 PhD-students
Programs (students/year)
• Medicine – 6 years (100)• Dentistry – 5 years (40)• Psychology – 5 years (35)• Pharmacy – 5 years (35)• Bioengineering (20) • Dental hygiene (18)• Ergo therapy (24)• Nursing (145), public health
nursing (20), midwife (20)• Physiotherapy (28)• Radio chart (30)• Masters in biomedicine (15),
telemedicine (5-10), laboratory medicine (new)
Selected Research Activities
• Large population based research The Tromsø Study since 1974 The Norwegian Women and Cancer Study
(NOWAC)• Marine Bioprospecting• Telemedicine and E-Health• Translational medical and health care research• Department specific activities
The Tromsø Study
• Population based study in Tromsø, run by UoT
• Starting point in 1974: High cardiovascular mortality in North-Norway
• Study extended to cancer, osteoporosis, diabetes, dementia – i.a. chronic diseases in ageing population, and skin diseases, bacterial colonization
• Screenings in 1974, 1979, 1986, 1994, 2001, 2008
• Repeated measurements and new birth cohorts
• Linked to disease and death registries of Norway
• A total of 40,000 participants
Tromsø Study Participants
Exposure Data
• Questionnaires
• Physiological measurements
• Serum/plasma
• Blood cells (DNA)
• Imaging data (carotid ultrasound, echocardio-/ retinography, bone scan)
Collaborations, Networks
• Biobank Norway (national infrastructure)
• MORGAM (Monica studies) CVD genetics
• DeCODE Genetics– atrial fibrillation genetics
• FUSION – Type 2 diabetes genetics
• IARC studies – cancer genetics
• ERFC – Emerging risk factors collaboration
• Tethys Bioscience Inc – novel biomarkers CVD
• EU FP7 CHANCES (Cohorts for healthy ageing networks Europe and US)
More Information - Tromsø Study
www.tromsoundersokelsen.no
- take a look at survey variables at
http://tromsoundersokelsen.uit.no/tromso
NOWAC – the Norwegian Women and Cancer Study
Random samples of Norwegian women
• 172 000 female participants recruited 1991-2006
• Questionnaire information, repeated up till three times
• Follow-up through linkage to national registers, and active search for biopsies of breast cancer and normal breast tissue
• Postgenome biobank with 50000 PAX tubes, plasma and ”buffy coat” (DNA)
TICE- Transcriptomics in Cancer Research
• The overall aim of the NOWAC postgenome cohort is to include transcriptomics (mRNA and miRNA) as part of the globolomic design in a population-based prospective study in order to explore systems epidemiology
• Transcriptomics in a globolomic design could be a measure of exposure, an intermediate in the carcinogenic process or classifying the outcome
• Supported by an Advanced Investigator Grant from The European Research Council in 2008
TICE - Aims
• Gene expression in peripheral blood as exposure indicator – biomarker (cross-sectional analysis)
• Diagnostic tests based on mRNA or miRNA for breast cancer (case-control)
• Prediagnostic tests based on blood gene expression (screening), all cancer sites (nested case-control in cohort design)
• Life style information and gene expression in relation to genetic profile of breast cancer and lung cancer
• Causal analysis of pathways• Contact information
nowac@ism. uit.no
MabCent- Research-based Innovation in Marine Bioprospecting
• Screen and characterize bioactive compound from Arctic and sub-Arctic marine organisms
• Research, innovation and commercialization
Anti-bacterial, anti-cancer, immunostimulants, anti-inflammatory, anti-diabetic, antioxidant
Specific enzyme activities and inhibitors
• MabCent activity and contact information is available at www.nfh.uit.no/mabcent
Norwegian Centre for Integrated Care and Telemedicine
• Hosted by the University Hospital of North-Norway in collaboration with UoT
• Links for further information: www.telemed.no and www.uit.no/telemed
• Tromsø Telemedicine Laboratory Telemedicine and E-health systems for
chronic, age, and lifestyle-related diseases www.telemed.no/ttl
Credits, clockwisefrom top left:
Jon Terje EiteråMaja SojtaricLars Nordmo
Ola RøeMaja SojtaricMaja SojtaricRolf E. Tønne
Photo: Jon Terje Eiterå
”Tromsø is a city for great occasions” Norwegian Secretary of State Jonas Gahr Støre, December 2005