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Page 1: Xanthogranulomatous pyelonefritis

Xanthogranulomatous Xanthogranulomatous Pyelonephrit isPyelonephrit is

� Rare severe chronic renal infectionRare severe chronic renal infection� Obstructive infective uropathy secondary to Obstructive infective uropathy secondary to

calculicalculi� Lipid-laden macrophages - xanthoma cellsLipid-laden macrophages - xanthoma cells� Chronic clinical course of flank pain, fever Chronic clinical course of flank pain, fever

and bacteriuria with malaise.and bacteriuria with malaise.� Retroperitoneal inflammatory reactionRetroperitoneal inflammatory reaction

Page 2: Xanthogranulomatous pyelonefritis

Investigation;Investigation;� KUB - calculiKUB - calculi� CT Scan - renal mass with multiple small CT Scan - renal mass with multiple small

abscessesabscesses

Management;Management;� Nephrectomy ± colectomy / splenectomyNephrectomy ± colectomy / splenectomy� Cutaneous FistulaCutaneous Fistula


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