©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 1
21 rue la Noue Bras de Fer44200 NANTES - FRANCE +33 2 40 18 09 16 [email protected] www.systemplus.fr
Thermo Fisher Ion 520Sample Tracking & DNA Sequencing ChipMEMS report by Stéphane ELISABETHJuly 2017 – version 1
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 2
Overview / Introduction 3
o Executive Summary
o Reverse Costing Methodology
Company Profile 6
o Thermo Fisher Scientific
o Leadership of Thermo Fisher
o Thermo Fisher Revenue Profile
o NGS – Next-Gen Sequencing – Ion Torrent Technology
o Thermo Fisher Ion Torrent Semiconductor Chip
o Microfluidic Market & Supply Chain
Physical Analysis 18
o Synthesis of the Physical Analysis
o Physical Analysis Methodology
o Package 21
Package Views & Dimensions
X-Ray Views
Package Opening
Package Cross-Section: PCB Substrate , Flow Cell Member, Wire Bonding
o Die 43
Details View: Flow Chamber, Pixels
View, Dimensions& Marking
Active Area Deprocessing
Die Delayering
Die Process
Die Cross-Section: Metal Layers, Active Area, ISFET
Process Characteristics
Table of Contents
Manufacturing Process Flow 70
o Global Overview
o Front-End Process
o Wafer Fabrication Unit
o Sensor Layers Process Flow
o Packaging Process Flow
Cost Analysis 81
o Synthesis of the cost analysis
o Yields Explanation & Hypotheses
o Die 86
Wafer Front-End Cost
Sensor Layers Wafer Front-End Cost
Sensor Layers Front-End Cost per process steps
Total Front-End Cost
Back-End 0 : Probe Test & Dicing
Wafer & Die Cost
o Component 92
Back-End : Packaging Cost
Back-End : Packaging Cost per Process Steps
Back-End : Final Test Cost
Component Cost
Estimated Price Analysis 97
Company services 101
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 3
Overview / Introduction
Company Profile & SupplyChain o Thermo Fishero NGS Ion Torrent Tech.o Market & Supply Chain
Physical Analysis
Manufacturing Process Flow
Cost Analysis
Selling Price Analysis
About System Plus
Microfluidic Market
Source : Yole Development
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 4
Overview / Introduction
Company Profile & SupplyChain
Physical Analysiso Package Overviewo Package Cross-Sectiono Die Overviewo Die Cross-Section
Manufacturing Process Flow
Cost Analysis
Selling Price Analysis
About System Plus
Synthesis of the Physical Analysis
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 5
Overview / Introduction
Company Profile & SupplyChain
Physical Analysiso Package Overviewo Package Cross-Sectiono Die Overviewo Die Cross-Section
Manufacturing Process Flow
Cost Analysis
Selling Price Analysis
About System Plus
Package View & Dimensions
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 6
Overview / Introduction
Company Profile & SupplyChain
Physical Analysiso Package Overviewo Package Cross-Sectiono Die Overviewo Die Cross-Section
Manufacturing Process Flow
Cost Analysis
Selling Price Analysis
About System Plus
Package – X-Ray Views
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 7
Overview / Introduction
Company Profile & SupplyChain
Physical Analysiso Package Overviewo Package Cross-Sectiono Die Overviewo Die Cross-Section
Manufacturing Process Flow
Cost Analysis
Selling Price Analysis
About System Plus
Package Cross-Section
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 8
Overview / Introduction
Company Profile & SupplyChain
Physical Analysiso Package Overviewo Package Cross-Sectiono Die Overviewo Die Cross-Section
Manufacturing Process Flow
Cost Analysis
Selling Price Analysis
About System Plus
Die – View & Dimensions
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 9
Overview / Introduction
Company Profile & SupplyChain
Physical Analysiso Package Overviewo Package Cross-Sectiono Die Overviewo Die Cross-Section
Manufacturing Process Flow
Cost Analysis
Selling Price Analysis
About System Plus
Die – Active Area
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 10
Overview / Introduction
Company Profile & SupplyChain
Physical Analysiso Package Overviewo Package Cross-Sectiono Die Overviewo Die Cross-Section
Manufacturing Process Flow
Cost Analysis
Selling Price Analysis
About System Plus
Die Cross-Section – Metal Layers
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 11
Overview / Introduction
Company Profile & SupplyChain
Physical Analysiso Package Overviewo Package Cross-Sectiono Die Overviewo Die Cross-Section
Manufacturing Process Flow
Cost Analysis
Selling Price Analysis
About System Plus
Die Cross-Section – ISFET
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 12
Overview / Introduction
Company Profile & SupplyChain
Physical Analysis
Manufacturing Process Flowo Front-End Process o Wafer Fabrication Unito Sensor Layers Process Flowo Packaging Process Flow
Cost Analysis
Selling Price Analysis
About System Plus
Global Overview
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 13
Overview / Introduction
Company Profile & SupplyChain
Physical Analysis
Manufacturing Process Flowo Front-End Process o Wafer Fabrication Unito Sensor Layers Process Flowo Packaging Process Flow
Cost Analysis
Selling Price Analysis
About System Plus
Process Flow (1/2)
drawing not to scale
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 14
Overview / Introduction
Company Profile & SupplyChain
Physical Analysis
Manufacturing Process Flowo Front-End Process o Wafer Fabrication Unito Sensor Layers Process Flowo Packaging Process Flow
Cost Analysis
Selling Price Analysis
About System Plus
Packaging Process Flow 1/3
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 15
Overview / Introduction
Company Profile & SupplyChain
Physical Analysis
Manufacturing Process Flow
Cost Analysiso Synthesis of cost analysiso Yield Explanationo Front-End Costo Die Costo Packaging Costo Component Cost
Selling Price Analysis
About System Plus
Front-End Cost
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 16
Overview / Introduction
Company Profile & SupplyChain
Physical Analysis
Manufacturing Process Flow
Cost Analysiso Synthesis of cost analysiso Yield Explanationo Front-End Costo Die Costo Packaging Costo Component Cost
Selling Price Analysis
About System Plus
Wafer & Die Cost
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 17
Overview / Introduction
Company Profile & SupplyChain
Physical Analysis
Manufacturing Process Flow
Cost Analysiso Synthesis of cost analysiso Yield Explanationo Front-End Costo Die Costo Packaging Costo Component Cost
Selling Price Analysis
About System Plus
Component Cost
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 18
Overview / Introduction
Company Profile & SupplyChain
Physical Analysis
Manufacturing Process Flow
Cost Analysis
Selling Price Analysiso Manufacturer Financialo Estimated Price
About System Plus
Estimated Manufacturer Price
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 19
Overview / Introduction
Company Profile & SupplyChain
Physical Analysis
Manufacturing Process Flow
Cost Analysis
Selling Price Analysis
About System Pluso Company serviceso Related reportso Feedbackso Contacto Legal
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©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 20
COMPANYSERVICES
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 21
Overview / Introduction
Company Profile & SupplyChain
Physical Analysis
Manufacturing Process Flow
Cost Analysis
Selling Price Analysis
About System Pluso Company serviceso Related reportso Feedbackso Contacto Legal
Business Models Fields of Expertise
Custom Analyses(>130 analyses per year)
Reports(>40 reports per year)
Costing Tools
Trainings
©2017 by System Plus Consulting | Thermo Fisher Ion 520 DNA Sequencing Chip 22
Overview / Introduction
Company Profile & SupplyChain
Physical Analysis
Manufacturing Process Flow
Cost Analysis
Selling Price Analysis
About System Pluso Company serviceso Related reportso Feedbackso Contacto Legal
Contact
Headquarters21 rue La Noue Bras de Fer44200 NantesFRANCE+33 2 40 18 09 [email protected]
Europe Sales OfficeLizzie LEVENEZFrankfurt am MainGERMANY+49 151 23 54 41 [email protected]
America Sales OfficeSteve [email protected]
www.systemplus.fr
Asia Sales OfficeTakashi [email protected]
Mavis WANGGREATER [email protected]
NANTESHeadquarter
FRANKFURT/MAINEuropa Sales Office
LYONYOLE HQ
TOKYOYOLE KK
GREATER CHINAYOLE
PHOENIXYOLE Inc.
KOREAYOLE