SILK FIBROIN WOUND DRESSINGS

Used for Regenerative Healing TherapiesSierra ObiApril 1, 2013

Cutaneous Wounds

Include severe burns, animal bites, skin tears There are numerous wound dressing biomaterials

on the market today Tested against an air permeable and a commercial

wound dressing product

Silk Fibroin

Promising biomaterial Versatile for various biomedical healing

applications Mechanical robustness Controllable degradability Safe in acute dermal toxicity

How They Work

Silk Fibroin derivative is tested on a full thickness skin wound model or an in vitro human skin model

controlled release of signaling molecules Addition of in vivo epidermal growth factor and

silver sulfadiazine

Wound Healing Model

Relationship of Wound Size

References

http://onlinelibrary.wiley.com/doi/10.1002/adhm.201200444/full

http://onlinelibrary.wiley.com/doi/10.1002/adhm.201200192/full

http://www.sciencedirect.com/science/article/pii/S1742706108004054

http://www.nejm.org/doi/full/10.1056/NEJMra0707253