Umberto
Veronesi
presentado por
Roberto Orecchia
Director Scientifico
IEO in Milan & CNAO in Pavia
5th November 2017
On November 8th,
we lost
a visionary and true
gentleman
During his long and
productive life,
he made significant
contribution
to surgical science,
to cancer care and
prevention, and
to medical education
From
Maximum tolerable
treatment
New Paradigm
To
Minimum effective
treatment
The Breast
model
ABVD
CMF
In Milan
the hystory
of breast
cancer
changed
….. In the italian study, begun in 1973 by Dr Umberto Veronesi …..
Months
Pro
bab
ility
0 60 120 180 240 300
0.0
0.2
0.4
0.6
0.8
1.0
Halsted (349)
Quadrantectomy + RT (352)
1981; Milan I trial - Survival
Milan
Trial
0
1990
x 1
000
50
100
150
200
250
1980 2000 1990
NSABP
Trial
300
350
2010
Radical Mastectomy
Breast Conserving Surgery
• Radiotherapy after breast-conserving surgery in women with localized cancer of the breast (N Engl J Med, 1993)
• Avoiding axillary dissection in breast cancer surgery: a randomized trial to assess the role of axillary radiotherapy (Ann Oncol, 2005)
• Intraoperative radiotherapy versus external radiotherapy for early breast cancer (ELIOT): a randomized controlled equivalence trial (Lancet Oncol, 2013)
CNAO – Pavia – May 2001
III
II
I
Sentinel Node Biopsy in Breast Cancer
European Institute of Oncology (1996 - 2017)
Radiotherapy after breast-conserving surgery in women with localized cancer of the breast
(N Engl J Med, 2003)
Follow-up (years)
Pro
po
rtio
n o
f p
ati
en
ts s
urv
ivin
g (
%)
Sentinel-lymph-node biopsy as a staging procedure in breast cancer: update of a randomised
controlled study (Lancet Oncol, 2006)
• Science for the Peace
• Future of Science Conventions
• European School of Oncology
• EUSOMA
• EURAMA
• AIRC
• European Institute of Oncology
• Umberto Veronesi Foundation
• Europa Donna
• International Society of Cancer Chemoprevention
• Committee of Cancer Expert of the European Union
• International Union Against Cancer
• Federation of the European Cancer Societies
• EORTC
• International Group for Melanoma
And in 2014 he passed the torch
Many Thanks, Umberto !