PATHOLOGY OF THE
FEMALE GENITAL TRACT II,
PATHOLOGY OF BREAST
X. practical training
3rd year General Medicine
Condyloma accuminatum of the vulva
Transformation zone
Cervical squamous neoplasia
Cervical
carcinoma
Poorly differentiated (nonkeratinizing)
squamous cell carcinoma of the cervix
Poorly differentiated (nonkeratinizing)
squamous cell carcinoma of the cervix
Endometrium, cyclus
1 2 3 4 1 early
proliferation
2 late
proliferation
3 early secretion
4 late secretion
Hyperplastic endometrium
1 Hyperplastic endometrium
2 Polypous endometrial hyperplasia
1 1
2
Dysfunctional hyperplastic proliferative
endometrium
Leiomyoma of the uterus
2
1
3
2
1 Subserous myoma
2 Intramural myoma
3 Submucous myoma
4 „born“ submucous myoma
4
Leiomyoma of the uterus copy
Leiomyoma of the uterus
Leiomyoma Leiomyosarcoma
1 1
1
Mitosis copy
Uterine corpus
carcinoma
Uterine corpus
carcinoma
Adenokarcinom (endometroidní) těla děložního
Residua post abortum
Hydatidiform mole
Hydatidiform mole
1
2
1 Edematózní bezcévné klky
2 Povrchová část klků
Hydatidiform mole
Chorionepithelioma (choriocarcinoma)
Ectopic (tubal) pregnancy
1
2
3
4
5
6
7
1 Serosis of tube
2 Wall of tube -
muscularis propria
3 Mucosal villi
4 Columnar epithelium
of tube
5 Coagulated haematoma
6 Hydropic degenera
tion of chorionic villi
7 Cytotrofoblastic cells
Abnormalities in
breast
development
Fibrocystic
disease
Fibrocystic disease
Fibrocystic disease
Histologic grading of mammary carcinomas
Body
1 Duct formation > 75% of the tumour 1
10 – 75% of the tumour 2
< 10% of the tumour 3
2 Nuclear atypia uniforme nuclei 1
small variability 2
large nuclei, marked atypia 3
3 Mitotic activity 0 - 8 MF 1
(2,5 mm2, 5 HPF) 9 – 17 MF 2
18 and more MF 3
score 3-5 = grade 1, score 6-7 = grade 2, score 8-9 = grade 3
Breast fibroadenoma
Commedocarcinoma (IDC)