NECESSITY FOR BLOOD CLOTTING
SEALS A WOUNDPREVENT EXCESSIVE BLOODLOSS FROM THE BODY
PREVENTS THE ENTRY OFMICROORGANISMS AND FOREIGN PARTICLESINTO THE BODY THROUGHTHE WOUND
PREVENTS BLOOD PRESSURE FROM FALLINGTO A LOW LEVEL AS PRESSURE IS NEEDED
MECHANISM OF BLOOD CLOTTING
INJURY/RUPTURE IN BLOOD VESSELS(accidentally cut the finger and bleedings)
PLATELETS CLUMP AT THE WOUND(platelets in the blood become sticky and clump togetherto plug the wound, so it can reduce blood loss)
release
THROMBOKINASE (clotting factor VIII)converts
PROTHROMBIN (in the liver)
THROMBIN (active enzyme)
Vitamin Kconverts
Calcium ions
Fibrinogen(soluble plasmaprotein)
Fibrin(insolublefibres)
a meshwork of threads overthe wound
Trap erythrocytes& platelets
Blood Clottingforms
Scab falls off, form newskin
CONSEQUENCES OF AN IMPAIRED BLOOD CLOTTING MECHANISM
DISEASEDISEASE CAUSES BY HOW TO OVERCOME/PREVENT/REDUCE
HAEMOPHILIA • lack of gene for productionof clotting factor (factor VIII)• an impaired clotting mechanismwhich causes serious bleeding• haemophiliacs may die of internalor external bleeding.
• factor VIII can now be produced by generic engineering
THROMBOSIS • a local blood clot (thrombus) is formed on the damaged rough inner wall of the artery.• blockage of the artery.
• Thrombus dislodge and is carried away by blood circulation(embolus)• embolus trapped & block the blood flow.
EMBOLISM
HEART ATTACK • the coronary artery is partially blocked.• cuts off the supply of oxygen andnutrients to the heart muscle.• extensive heart muscle damagecan cause death.
• avoid to take foodsrich in fats• consume more fruits and vegetables• exercise and practise a healthy lifestyle