Heat SealingHeat sealing is the gold standard plate sealing method, minimising sample loss and maximising sample security, for PCR, qPCR, storage and other applications.
IMAGES?
The sealing performance of heat seals is superior to cap, mat and adhesive sealing with clear reductions in sample loss and cross contamination. The optimized sealing performance allows use of smaller reaction volumes leading to reagent savings.
Heat sealing is the most cost efficient way to seal plates for a wide range of applications. Per well comparisons show a 3 to 5 five fold reduction in costs for qPCR application (list price comparison of Clear Weld Seal against caps and qPCR seal) and at least a 50% reduction for storage solutions (list price comparison of Peel Seal against caps and PCR seal). Costs can be further reduced by changing to use of the material format, using rolls rather than sheets.
The application of a heat seals is much faster than caps or adhesive seals. Typical sealing times are around 2,5 seconds. Depending on throughput the use of a semi-automatic or fully automatic heat sealer can guarantee a reproducible sealing quality by standardising the sealing parameters, time, temperature and pressure. Sealing performance variability between different users can be eliminated.
4titude® offers a wide choice of heat seals in both roll and sheet format. Different seals can be chosen to optimize the use depending on plate material, desired permeability or resistance, ability to peel or pierce the seal material and visualisation through the material. Please refer to the comparison table on page 73 for an overview of our heat sealing range.
All seals are certified free from nucleases and human genomic DNA contamination.
The best sealing results can be obtained by using flat, rigid plates with a raised rim design like our FrameStar® 2-component plates and reliable, high quality sealing instruments such as the 4s3 semi-automated heat sealer or the 4AS sealer.
For details of the instruments see page 62 and 64. For a demonstration or trial of a heat sealer please contact us at [email protected].
www.4ti.co.uk | 61 +44 (0)1306 884885 www.4ti.co.uk | 61 +44 (0)1306 884885
Hea
t Se
alin
g
PEELABLE
A
UTOCLAVABLE
121o
ClearsealisanopticallyclearfilmwhichformsaneasilypeelableyetPCR/qPCRtightseal.Itsopticalclarityallowsuseforallopticalapplications.Theclearsealcanbeusedtosealmostplatetypesincludingpolypropylene,polyethylene,polystyreneandCOCplates.Availableassheetsoronarollforautomatedsealers.
Clear Seal
Applications
• qPCRorotheropticalapplications(e.g.fluorescenceorcolorimetricassays)
• Shorttermcompoundstorage
• Suitableformostplatematerials
• Availableinsheetorrollformatforautomatedsealers
• FreefromDNase,RNaseandhumangenomicDNA
Clearweldsealisanopticallyclearpolymerfilmwhichformsapermanentbondtopolypropyleneplatesthatcannotbepeeledandisdifficulttopierce.Thesealhasagoodsolventresistanceforsafelongtermstorage.
Samplecanbeaccessedifrequiredusingabladeorneedle.
NowalsoavailableasFrameSealproductseepage75
Clear Weld Seal Mark II
Applications
• PCR
• waterbaththermalcyclers
• qPCRandotheropticalapplications(e.g.fluorescenceandcolorimetricassays)
• Storageanddisposalofhazardousmaterials
• RecommendedforusewithDMSO
• Availableassheetsorinrollformatforautomatedsealers
• FreefromDNase,RNaseandhumangenomicDNA
*(110Cwithpressurisedheatedlid)
SE
AL
INT
EG
R
ITY TEMPERATU
RE
RA
NG
E
-80°
80°
*
*Onceautoclaved,notrecommendedforPCRapplications
SE
AL
INT
EG
R
ITY TEMPERATU
RE
RA
NG
E
-80°
110°
*
Code Pack Size/Dimensions
4ti-0573 610mx78mmroll1Approx5000seals
4ti-0573S Trialroll15mx78mm
4ti-0574 500mx115mmroll2Approx6250seals
4ti-0574S Trialroll25mx115mm
4ti-0575 100sheets(125mmx78mm)
4ti-0575/FS SealingFrame:50seals/frameperpack
Code Pack Size/Dimensions
4ti-0540 500mx78mmroll1Approx4200seals
4ti-0540/REMP 500mx78mmroll3Approx4200seals
4ti-0540S Trialroll15mx78mm
4ti-0542 350mx115mmroll2Approx4400seals
4ti-0542/REMP 500mx115mmroll4Approx6250seals
4ti-0542S Trialroll
4ti-0541 100sheets(125mmx78mm)5mx115mm
NEW
| www.4ti.co.uk66 +44 (0)1306 884885
Heat Sealing
TheClearSeal3730isaclearpolyesterbackedfilmwhichisparticularlythin.Itsealstopolypropylene,polystyrene,polyethyleneandCOCmicroplates.Thissealhasgoodopticalclaritywithmoderatesolventresistance.Thethinnatureofthissealenablesittobeeasilypiercedwithanauto-samplerneedle,ortheprobefromtheABi3730sequencer.
Thesealisonlyavailableinrollformat,butarollwithperforatedsheetscanbeusedforlowthroughput.
Clear Seal 3730
Applications
• PCR
• qPCRandotheropticalapplications(e.g.fluorescenceandcolorimetricassays)
• Piercablebyautosamplesneedles
• PiercablebytheABI3730
• Availableinrollformatforautomatedsealers
• FreefromDNase,RNaseandhumangenomicDNA
PIERCEABLE
ThispopularlaminatematerialgivesapeelableheatsealtoPPandCOCplates.Itcanbepeeleddirectlyfromtheplatefollowingremovalfromthefreezerandisagoodbarriertoaqueoussolutions.Thesealshowsmoderateresistancetosolventsatroomtemperatureandformsaweld-sealtopolyethyleneplates(cannotbepeeled).
Peel Seal
Applications
• Verylowtemperaturecompoundstorage.
• Mid-term(<5days)roomtemperaturecompoundstorage
• PCR
• Availableassheetsorinrollformatforautomatedsealers
• FreefromDNase,RNaseandhumangenomicDNA
1 Compatible with Thermo Fisher ALPS 300™ / ALPS 3000™ /
KBiosystems Wasp™ / KBioscience FlexiSeal and Cube2 Compatible with Agilent (Velocity 11) PlateLoc®
3 Compatible with REMP Portrait Heat Sealer (PHS)4 Compatible with REMP Landscape / Stacking Heat
Sealers (LHS/SHS)
COC = Cyclic Olefin Copolymer
SE
AL
INT
EG
R
ITY TEMPERATU
RE
RA
NG
E
-20°
80°
*(110C with pressurised heated lid)
*
*(110CwithpressurisedPCRheatedlid)
A
UTOCLAVABLE
121o
PEELABLE
SE
AL
INT
EG
R
ITY TEMPERATU
RE
RA
NG
E
-200°
90°
*
Code Pack Size/Dimensions
4ti-0580 610mx78mmroll1Approx5000seals
4ti-0580S Trialroll15mx78mm
4ti-0582 500mx115mmroll2Approx6250seals
4ti-0582S Trialroll25mx115mm
4ti-0581 Rollof1000perforatedsheets125mmx78mm
Code Pack Size/Dimensions
4ti-0520 610mx78mmroll1Approx5000seals
4ti-0520S Trialroll15mx78mm
4ti-0522 500mx115mmroll2Approx6250seals
4ti-0522S Trialroll25mx115mm
4ti-0521 100sheets(125mmx78mm)
www.4ti.co.uk | 67 +44 (0)1306 884885
Hea
t Se
alin
g
Pierce Seal
PEELABLE
ThislaminatematerialgivesapeelableheatsealtopolypropyleneandCOCplates.Itcanbepeeleddirectlyfromtheplateimmediatelyafterremovalfromthefreezer.TheDMSOresistantpeelsealisanexcellentbarriertoaqueoussolutionsandsolvents,inparticularDMSO,evenatroomtemperature.
Itformsaweld-sealtopolyethyleneplates(cannotbepeeled),requiringabladeorneedleforaccess.
DMSO Resistant Peel Seal
Applications
• LowandroomtemperaturecompoundstoragewithDMSO*andotherorganicsolvents
• 100%DMSOcanbestoredatroomtemperaturefor12monthswithnodeteriorationofthesealquality
• Availableinsheetandrollformatforautomatedsealers
• FreefromDNase,RNaseandhumangenomicDNA
Thisfoil-basedheatsealissuitablefortopolypropyleneandpolystyreneplatesandcanbeeasilypiercedwithamanualorautopipettetip.Ithasverygoodsolventresistance,includingtoDMSO.Sealscanbeappliedontopofeachotherallowingmultipleaccess/resealingofsamples.Abluecolourprintidentifiesthenon-sealingsurfaceforeaseofapplication.Thissealremainsintacttoveryhightemperatures.
Applications
• PCR
• LowandroomtemperaturecompoundstoragewithDMSOandotherorganicsolvents
• Sampleshipping
• Availableinsheetandrollformatforautomatedsealers
• FreefromDNase,RNaseandhumangenomicDNA
SE
AL
INT
EG
R
ITY TEMPERATU
RE
RA
NG
E
-80°
40°
A
UTOCLAVABLE
121o
PIERCEABLE
SE
AL
INT
EG
R
ITY TEMPERATU
RE
RA
NG
E
-20°
120°
Code Pack Size/Dimensions
4ti-0585 500mx78mmroll1Approx4200seals
4ti-0585/REMP 500mx78mmroll3Approx4200seals
4ti-0585S Trialroll15mx78mm
4ti-0586 500mx115mmroll2Approx6200seals
4ti-0586/REMP 500mx115mmroll4Approx6200seals
4ti-0586S Trialroll25mx115mm
4ti-0587 100sheets(125mmx78mm)
Code Pack Size/Dimensions
4ti-0530 610mx78mmroll1Approx5000seals
4ti-0530/REMP 610mx78mmroll3Approx5000seals
4ti-0530S Trialroll1
4ti-0532 500mx115mmroll2Approx6200seals
4ti-0532/REMP 500mx115mmroll4Approx6200seals
4ti-0532S Trialroll2
4ti-0531 100sheets(137mmx76mm)
| www.4ti.co.uk68 +44 (0)1306 884885
Heat Sealing
TheINDISealisafoil-basedheatsealthatsealstopolypropyleneandissuitableforlowtemperaturestorage.Thesealconsistsof96perforatedindividualsealingcapsinafoilframe.Theframeisremovedafterheatsealingleavingeachwellwithanindividualairtightseal.Thesealshavetabsforeasyremovalbyhandorwithforceps,withoutleavinganyresidue.
Mainlydevelopedforusewithtubesinclusterrackssomeplatescanalsobesealed.
Re-sealingandpiercingarepossible.
96 INDI™ Seal
Applications
• Compoundstorage
• Sampleshipping
• FreefromDNase,RNaseandhumangenomicDNA
AnaluminiumheatsealthatsealstoPPandPSplatesandcanbepiercedwithapipettetiporpeeledbyhand.GoodsolventresistanceincludingDMSO.Resealingontoanexistingsealispossible.Aredcolourprintidentifiesthenon-sealingsurfaceforeaseofapplication.
Foil Seal
Applications
• Lowtemperaturecompoundstorage
• Short-termroomtemperaturecompoundstorage
• PCR
• Resealable
• Availableinsheetandrollformatforautomatedsealers
• FreefromDNase,RNaseandhumangenomicDNA
PEELABLE
A
UTOCLAVABLE
121o
PIERCEABLE
SE
AL
INT
EG
R
ITY TEMPERATU
RE
RA
NG
E
-0°
110°
PIERCEABLEPEELABLE
SE
AL
INT
EG
R
ITY TEMPERATU
RE
RA
NG
E
-195°
120°
Code Pack Size/Dimensions
4ti-0543 INDISealforindividualtubesealing
(125mmx78mmsheets) 50sheets
Code Pack Size/Dimensions
4ti-0535 610mx78mmroll1Approx5000seals
4ti-0535/REMP 610mx78mmroll3Approx5000seals
4ti-0535S Trialroll15mx78mm
4ti-0537 500mx115mmroll2Approx6200seals
4ti-0537/REMP 610mx115mmroll4Approx6200seals
4ti-0537S Trialroll25mx115mm
4ti-0536 100sheets(125mmx78mm)1 Compatible with Thermo Fisher ALPS 300™ / ALPS 3000™ /
KBiosystems Wasp™ / KBioscience FlexiSeal and Cube2 Compatible with Agilent (Velocity 11) PlateLoc®
3 Compatible with REMP Portrait Heat Sealer (PHS)4 Compatible with REMP Landscape / Stacking Heat
Sealers (LHS/SHS)
COC = Cyclic Olefin Copolymer
www.4ti.co.uk | 69 +44 (0)1306 884885
Hea
t Se
alin
g
Thisisaheavydutylaminatematerialthatsealstopolypropylenetogiveaverystrongbutpeelableseal.Thissealaffordsahighdegreeofsampleprotection.GoodsolventresistanceincludingDMSO.
Thermal Bond
Applications
• Longtermstorage,includingstorageandtransportationatlowtemperature
• Storageoforganicsolvents,acidsandalkalinesincludingDMSO
• PCR
• Suitableforwaterbaththermalcyclers
• Availableinsheetandrollformatsforautomatedsealers
• FreefromDNase,RNaseandhumangenomicDNA
A
UTOCLAVABLE
121o
PEELABLE
SE
AL
INT
EG
R
ITY TEMPERATU
RE
RA
NG
E
-200°
110°
Thepolystyrenefoilsealcreatesastrong,butpeelablesealtopolystyreneplates.Thesealcanalsobepiercedwithapipettetipandhasagoodsolventresistance,includingtoDMSO.Resealingontoanexistingsealispossible.
Polystyrene Foil Seal
Applications
• Lowtemperaturecompoundstorage
• Short-termroomtemperaturecompoundstorage
• Resealingispossible
• FreefromDNase,RNaseandhumangenomicDNA
Code Pack Size/Dimensions
4ti-0547 100sheets(125mmx78mm)
PIERCEABLEPEELABLE
SE
AL
INT
EG
R
ITY TEMPERATU
RE
RA
NG
E
-20°
110°
Code Pack Size/Dimensions
4ti-0590 500mx78mmroll1Approx4200seals
4ti-0590S Trialroll15mx78mm
4ti-0592 300mx115mmroll2Approx3700seals
4ti-0591 100sheets(125mmx78mm)5mx78mm
| www.4ti.co.uk70 +44 (0)1306 884885
Heat Sealing
Thisisafoil-basedheatsealwhichiscoatedonthesealingsurfacewithalowautofluorescenceblackpigmentforusewithlightsensitivesamplesorforfluorescentassays.TheBlackSealformsapeelablesealtopolystyreneplates.
Black Seal
Applications
• Fluorescentandotherlightsensitiveassays.
• Pierceswithaforcegreaterthan10N(ASTMD1000)
• Availableinsheetandrollformatsforautomatedsealers
• FreefromDNase,RNaseandhumangenomicDNA
1 Compatible with Thermo Fisher ALPS 300™ / ALPS 3000™
/ KBiosystems Wasp™ / KBioscience FlexiSeal and Cube2 Compatible with Agilent (Velocity 11) PlateLoc®
COC = Cyclic Olefin Copolymer
Code Pack Size/Dimensions
4ti-0525 610mx78mmroll1Approx5000seals
4ti-0526 500mx115mmroll2Approx6200seals
4ti-0527 100sheets(125mmx78mm
PEELABLE
SE
AL
INT
EG
R
ITY TEMPERATU
RE
RA
NG
E
-20°
80°
PIERCEABLE
ThisheatsealhasasmallerporesizethanthediscontiunedGasPermeableSeal(4ti-0596)whichstillallowsforgaseousexchange,butlimitsevaporation.Handlinginautomatedsealersisimproved.TheGasPermeableHeatSealMk2issuitableforcellcultureandisavailableassterileproductforthisapplication.
Gas Permeable Seal Mk 2
Applications
• Cellculture
• Overnightincubation
• Seedandinsectstorage
• Permeabilityrateis>20g/m2/24h
• Poresizeis<20µm
• Availableinsheetandrollformatforautomatedheatsealers
• FreefromDNase,RNaseandhumangenomicDNA
A
UTOCLAVABLE121o
PEELABLE
PIERCEABLESTERILE
SE
AL
INT
EG
R
ITY TEMPERATU
RE
RA
NG
E-20°
80°
Code Pack Size/Dimensions
4ti-0598 GasPermeableSealMk2roll(610mx78mm)1Approx5000seals 1roll
4ti-0598/ST GasPermeableSealMk2roll,sterile(610mx78mm)1
Approx5000seals 1roll
4ti-0599 GasPermeableSealMk2roll(500mx115mm)2Approx6200seals 1roll
4ti-0599/ST GasPermeableSealMk2roll,sterile(500mx115mm)2
Approx6200seals 1roll
4ti-0597 GasPermeableSealMk2sheets(125mmx78mm) 100sheets
4ti-0597/ST GasPermeableSealMk2sheets,sterile(125mmx78mm) 100sheets
(10packsx10sheets)
www.4ti.co.uk | 71 +44 (0)1306 884885
Hea
t Se
alin
g
Gas Permeable Clear Seal
Applications
• Insectstudies
• Seedstorage
• Availableinsheetandrollformatforautomatedsealers
• FreefromDNase,RNaseandhumangenomicDNA
PEELABLE
SE
AL
INT
EG
R
ITY TEMPERATU
RE
RA
NG
E
-80°
110°
Thisisaclearpolymerfilmformingapeelablesealtopolypropylene,polyethylene,polystyreneandCOCplateswithgoodopticalclarityandmoderatesolventresistance.Thefilmhas3mmslitsacrosstheentirewidthoftherollorsheet,allowinggaseousexchange.DuetoitswidertemperaturetolerancecomparedtotheGasPermeableHeatSealitcanbeusedforstoragee.g.forseedsorinsects.
Code Pack Size/Dimensions
4ti-0540/SLIT 480mx78mmroll1Approx4000seals
4ti-0541/SLIT 100sheets(125mmx78mm)
1 Compatible with Thermo Fisher ALPS 300™ / ALPS 3000™
/ KBiosystems Wasp™ / KBioscience FlexiSeal and Cube2 Compatible with Agilent (Velocity 11) PlateLoc®
COC = Cyclic Olefin Copolymer
| www.4ti.co.uk72 +44 (0)1306 884885
Hea
t Sea
ling F
ilms &
Foils C
om
pariso
n T
able
Cle
ar S
ea
l
p6
6
Cle
ar W
eld
Se
al
Ma
rk II
p6
6
Cle
ar S
ea
l 3
73
0
p6
7
Pe
el S
ea
l
p6
7
DM
SO
Re
sistan
t Pe
el
Se
al
p6
8
Pie
rce S
ea
l
p6
8
Foil S
ea
l & P
S Fo
il S
ea
l
p6
9/7
0
Th
erm
al B
on
d
p7
0
Bla
ck Se
al
p7
1
Ga
s Pe
rme
ab
le
Se
al M
k 2
p7
1
Ga
s Pe
rme
ab
le
Cle
ar S
ea
l
p7
2
IND
I Se
al
p6
9
Ap
plicatio
nq
PC
R,
sho
rtterm
com
po
un
d
storag
e.
PC
R(esp
.water
bath),q
PC
R.
Sto
rage&
disp
osal
ofh
azardo
us
materials.
qP
CR
and
fo
rusew
ith
AB
i3730
S
equ
encer.
Lo
wtem
peratu
re,
com
po
un
dsto
rage,
sho
rttermro
om
temp
erature
com
po
un
dsto
rage
(<5d
ays),PC
R.
Lo
wtem
peratu
re/
roo
mtem
peratu
re
com
po
un
dsto
rage
with
DM
SO
&o
ther
org
anicso
lvents.
PC
R,co
mp
ou
nd
storag
e,samp
le
ship
pin
g
Lowtem
perature
compound
storage,short-term
room
temperature
compoundstorage,
PC
R.
Lowtem
perature
transportation&
storage.PC
R,esp.
waterbathcyclers.
Storageoforganicsolvents,acids
&alkalines.
Flu
orescen
t&
oth
erligh
tsen
sitiveassays
Cellcu
lture,o
vern
igh
tincu
batio
n,
seedan
din
sectsto
rage
Sto
ragee.g
.fo
rseedso
rin
sects
Co
mp
ou
nd
sto
rae,sam
ple
ship
pin
g
Sp
ecialP
rop
ertiesG
oo
do
ptical
clarity.
Mo
derate
solven
tresistan
ce.
Go
od
op
ticalclarity&
resistantto
DM
SO
.
Go
od
op
ticalclarity,
som
esolven
t
resistance.
Can
bep
eeled
directlyfro
m-8
0°C
freezer.Mo
derate
resistanceto
solven
tsatroo
m
temp
erature.
Can
bep
eeled
directlyfro
m-8
0°C
freezer.Hig
h
resistanceto
solven
tseven
atelevated
temp
eratures.
Easilypierceable.
ResistanttoD
MS
O.
Re-sealablew
ith
anotherPierceS
eal.
Colourprint
identifiesnon-
sealingsurface
Re-sealab
lewith
ano
therFo
ilSeal.
Resistan
ttoD
MS
O.
Co
lou
rprin
tid
entifi
esno
n-
sealing
surface.(Fo
ilS
ealon
ly)
Verystro
ng
sealw
ithP
P.Resistan
tto
DM
SO
and
oth
erso
lvents
Afo
il-based
h
eatseal,co
atedo
nth
esealin
gsu
rfacew
ithalo
w
flu
orescen
ceb
lackpig
men
t
Sm
allporesizethatallow
sgaseousexchange,but
limitsevaporation.
Perm
eabilityrate>20
g/sqm/24
h
20µmporesize
3m
mslits
acrossen
tiresu
rfaceofseal
makesth
isp
ermeab
leto
gases
96
perfo
rated
ind
ividu
alsealin
gcap
sin
afoil
frame.C
an
beresealed
Min
Temp
-80
°C-8
0°C
-20
°C-8
0°C
-80
°C-2
0°C
-20
°C-2
00
°C-8
0°C
-20
°C-8
0°C
-195
°C
MaxTem
p8
0°C
(or110
°Cw
ith
pressurised
PC
Rheatedlid)
110°C
80
°C(o
r110
°Cw
ith
pressu
rised
PC
Rh
eatedlid
)
90
°C(o
r110°C
with
p
ressurised
PC
R
heated
lid)
40
°C12
0°C
110°C
110°C
120
°C8
0°C
100
°C12
0°C
Piercab
le•
••
••
•
Peelab
le•
••
••
••
••
RN
ase/DN
asefree
••
••
••
••
••
•
Material
Lam
inate
Lam
inate
Po
lymer
Lam
inate
Lam
inate
Foil
Foil
Lam
inate
Foil
Wo
venm
aterialL
amin
ateL
amin
ate
Sealsto
PP,P
E,P
S,
CO
CP
PP
P,PE
,PS
,C
OC
PP,C
OC
PP,P
E
PP,P
SP
P,PS
PP
PS
PP,P
S,C
OC
PP,P
E,P
S,C
OC
PP
4s3sealingtim
ew
ith96
wellP
P
Plates(°C
/secs)^
175-18
5/2-3
175-18
5/2-3
165
-175/3
175-18
5/3
175-18
5/3
160
-175/2
165
-180
/2170
-180
/2-3-
170/2
175-18
5/2-3
175/3
4s3sealingtim
ew
ith384
wellP
P
Plates(°C
/secs)^
165
-180
/3170
-175/2-3
165
-175/2
170-175
/2-3170
-175/2-3
160
-175/2
165
-175/2-3
160
-170/2
-170
/216
5-18
0/3
-
4s3sealingtim
ew
ithVisionP
lates(°C
/secs)^
185
-20
0/3
-175
-185
/2-3-
-18
5-2
00
/318
5-2
00
/3-
185
-20
0/3
170/2
185
-20
0/3
-
Pro
du
ct Co
de
s
Ro
ll78m
m1
4ti-0
54
04
ti-05
734
ti-05
80
4ti-0
52
04
ti-05
85
4ti-0
53
04
ti-05
354
ti-05
90
4ti-0
52
54
ti-05
98
4ti-0
54
0/S
LIT
-
Ro
ll78m
m3
4ti-0
54
0/
RE
MP
4ti-0
573/R
EM
P4
ti-05
80
/R
EM
P4
ti-05
20
/RE
MP
4ti-0
58
5/R
EM
P4
ti-05
30
/RE
MP
4ti-0
535
/RE
MP
4ti-0
59
0/R
EM
P4
ti-05
25/R
EM
P4
ti-05
98
/RE
MP
--
Ro
ll115m
m2
4ti-0
54
24
ti-05
744
ti-05
82
4ti-0
52
24
ti-05
86
4ti-0
532
4ti-0
537
4ti-0
59
24
ti-05
264
ti-05
99
4ti-0
54
2/S
LIT
-
Ro
ll115m
m4
4ti-0
54
2/
RE
MP
4ti-0
574
/RE
MP
4ti-0
58
2/
RE
MP
4ti-0
52
2/R
EM
P4
ti-05
86
/RE
MP
4ti-0
532
/RE
MP
4ti-0
537/R
EM
P4
ti-05
92
/RE
MP
4ti-0
526
/R
EM
P4
ti-05
99/R
EM
P-
-
Packof100
sheets(125m
mx78
mm
)4
ti-05
41
4ti-0
54
54
ti-05
81
4ti-0
52
14
ti-05
87
#4
ti-05
31
4ti-0
53
64
ti-05
91
4ti-0
52
74
ti-05
97
4ti-0
54
1/SL
IT4
ti-05
43
#
Su
pp
liedo
nap
erforated
roll
^
Ad
d1seco
nd
toth
esealing
timew
hen
aweig
hted
platen
isused
(4ti-0
60
2)
1C
om
patib
lewith
Th
ermo
Fish
erAL
PS
s30
0™
/AL
PS
30
00
™/K
Bio
systemsC
ham
eleon
™/K
Bio
scienceFexiS
eal&R
emp/Tecan
PlateS
ealer2
C
om
patib
lewith
Ag
ilent(V
elocity11)P
lateLo
c®
3
Co
mp
atiblew
ithR
EM
PP
ortraitH
eatSealer(P
HS
0)
4
C
om
patib
lewith
RE
MP
Lan
dscap
e/Stackin
gH
eatSealers(L
HS
/SH
S)
PP
P
olyp
ropylen
eP
S
Po
lystyrene
CO
C
CyclicO
lefinC
op
olym
erP
E
Po
lythen
e
NB
S
om
esealsavailableassterileo
nreq
uest
R
ollsarealso
availableo
n15
0m
mco
reforR
emp/Tecan
sealers.Pleaseen
qu
ire.
www.4ti.co.uk | 73 +44 (0)1306 884885
Hea
t Se
al S
elec
tion
Tab
le
Thistablemakesitsimplerforyoutoselecttherightheatsealforyoursealer:
Choosewhichtypeofsealyourequireacrossthetopandfollowdowntothecorrectrowforyourheatsealer,listedontheleft.Takeanoteoftheproductcode.
Cle
ar
Se
al
p6
6
Cle
ar
We
ld S
ea
l M
ark
II
p6
6
Cle
ar
Se
al
37
30
p6
7
Pe
el
Se
al
p6
7
DM
SO
R
esi
sta
nt
Pe
el
Se
al
p6
8
Pie
rce
S
ea
l
p6
8
Foil
Se
al
p6
9
PS
Fo
il S
ea
l
p7
0
Th
erm
al
Bo
nd
p7
0
Bla
ck
Se
al
p7
1
Ga
s P
erm
ea
ble
S
ea
l M
k 2
p7
1
Ga
s P
erm
ea
ble
C
lea
r S
ea
l
p7
2
IND
I S
ea
l
p6
9
4ti
tud
e
4s3
4ti
-05
41
4ti
-05
754
ti-0
58
14
ti-0
52
14
ti-0
58
74
ti-0
531
4ti
-05
36
4ti
-05
47
4ti
-059
14
ti-0
52
74
ti-0
597
4ti
-05
41/
SL
IT4
ti-0
54
3
A4
S4
ti-0
54
04
ti-0
573
4ti
-05
80
4ti
-05
20
4ti
-05
85
4ti
-05
30
4ti
-05
354
ti-0
54
54
ti-0
59
04
ti-0
52
54
ti-0
59
84
ti-0
54
0/S
LIT
-
Ag
ilen
t
Pla
teL
oc
4ti
-05
42
4ti
-05
744
ti-0
58
24
ti-0
52
24
ti-0
58
64
ti-0
532
4ti
-05
37-
4ti
-05
92
4ti
-05
264
ti-0
59
9-
-
KB
iosc
ien
ce
Fle
xiS
eal
4ti
-05
40
4ti
-05
734
ti-0
58
04
ti-0
520
4ti
-05
85
4ti
-05
30
4ti
-05
35-
4ti
-05
90
4ti
-05
254
ti-0
59
84
ti-0
54
0/S
LIT
-
KB
iosy
ste
ms
E-F
ly2
4ti
-05
41
4ti
-05
754
ti-0
58
14
ti-0
52
14
ti-0
58
74
ti-0
53
14
ti-0
53
64
ti-0
54
74
ti-0
59
14
ti-0
52
74
ti-0
59
74
ti-0
54
1/S
LIT
4ti
-05
43
Was
p4
ti-0
54
04
ti-0
573
4ti
-05
80
4ti
-05
20
4ti
-05
85
4ti
-05
30
4ti
-05
35-
4ti
-05
90
4ti
-05
25
4ti
-05
98
4ti
-05
40
/SL
IT-
Cha
mel
eon™
4ti
-05
40
4ti
-05
734
ti-0
58
04
ti-0
52
04
ti-0
58
54
ti-0
53
04
ti-0
535
-4
ti-0
59
04
ti-0
52
54
ti-0
59
84
ti-0
54
0/S
LIT
-
RE
MP
Easy
Sea
ler
4ti
-05
41
4ti
-05
754
ti-0
58
14
ti-0
52
14
ti-0
58
74
ti-0
53
14
ti-0
53
64
ti-0
54
74
ti-0
59
14
ti-0
52
74
ti-0
59
74
ti-0
54
1/S
LIT
4ti
-05
43
Po
rtra
it4
ti-0
54
04
ti-0
573
4ti
-05
80
4ti
-05
20
4ti
-05
85
4ti
-05
30
4ti
-05
35-
4ti
-05
90
4ti
-05
25
4ti
-05
98
4ti
-05
40
/SL
IT-
Th
erm
o F
ish
er
AL
PS
30
0™
4ti
-05
40
4ti
-05
734
ti-0
58
04
ti-0
52
04
ti-0
58
54
ti-0
53
04
ti-0
535
-4
ti-0
59
04
ti-0
52
54
ti-0
59
84
ti-0
54
0/S
LIT
-
AL
PS
30
00
™4
ti-0
54
04
ti-0
573
4ti
-05
80
4ti
-05
20
4ti
-05
85
4ti
-05
30
4ti
-05
35-
4ti
-05
90
4ti
-05
25
4ti
-05
98
4ti
-05
40
/SL
IT-
AL
PS
™5
04
ti-0
54
14
ti-0
575
4ti
-05
81
4ti
-05
21
4ti
-05
87
4ti
-05
31
4ti
-05
36
4ti
-05
47
4ti
-05
91
4ti
-05
27
4ti
-05
97
4ti
-05
41/
SL
IT4
ti-0
54
3
ALP
S™2
54
ti-0
54
14
ti-0
575
4ti
-05
81
4ti
-05
21
4ti
-05
87
4ti
-05
31
4ti
-05
36
4ti
-05
47
4ti
-05
91
4ti
-05
27
4ti
-05
97
4ti
-05
41/
SL
IT4
ti-0
54
3
All
roll
seal
fo
rmat
sar
eav
aila
ble
ina
tri
alr
oll.
Ad
dS
to
th
een
do
fth
ep
rod
uct
co
de
too
rder
If
yo
uw
ou
ldli
kea
ssis
tan
cein
ch
oo
sin
gt
he
corr
ect
seal
fo
ryo
ur
app
licat
ion
an
dh
eat
seal
er,p
leas
eco
nta
ctt
ech
nic
als
up
po
rto
n+
44
(0
)13
06
88
48
85
or
info
@4
ti.c
o.u
k
Heat Seal Selection Table
| www.4ti.co.uk74 +44 (0)1306 884885
Code Description Qty
4ti-0575/FS ClearWeldSealMkIIFrameSealTM,stackableheatsealframes 50
4ti-0541/FS ClearSealFrameSealTM 50
4ti-0531/FS PierceSealFrameSealTM 50COMING SOON
FrameSealTMutilisesasheetofstandard4titude®heatsealmaterialmountedontoadisposable,rigid,plasticframe.AFrameSealTMcanbeplacedeithermanuallyorwitharoboticgripperontoawiderangeofskirtedandsemi-skirtedmicroplatesincludingPCRplatesandarecompatiblewiththe4S3heatsealer.Aftersealing,thereistheoptiontoremovetheframebytearingalongpre-cutlinesleavingtheheatsealinplaceontheplatesurface.
FrameSeal™
Application example:
OurClearWeldSealMkII(4ti-0575)heatsealingfilmisnowavailablepre-mountedtocreateaFrameSeal.TogetherwithFraunhofferIPAInstituteFrameSealTMhasbeenusedinafullyintegratedsolutionforsealing1536wellPCRplatesbeforeanalysisofRNAiscreeningwithaRocheLightcycler1536.
Usingaroboticarm,asingleFrameSealTMisplacedontoa1536wellPCRplate.Byadjustingthepositionoftherobotgripper,theplateandFrameSealTMcombinationarethentransferredtothedrawofa4S3HeatSealerwhichsealsthepartviaasoftwarecommandthroughitsRS232port.
Afterthesealingprocesshasbeencarriedout,thesealedplateistransferredtotheDe-Framer,whichseperatestheframefromthefilmateachpointalongtheedgeofthefilm.Theframecanthenberemovedleavingthesealedplatetobeplacedinthecycler.
TogethertheheatsealerandtheFrameSealTMpresentedhereare:
• Themostcosteffectiveautomatedheatsealingsolutionavailable
• Anapproachinlinewithdemandsofdiagnosticsforasterile,single-useconsumable
• Themostcompactinstrumentforintegration
4s3™shownnexttotheDe-Framer
Automationcell,showingthe4LAB™,4s3™andDe-Framerfullyintegrated
Key advantages
• Keyadvantagescomparedtosheetsofsealingfilmorrollmaterial,aretheeaseofhandlingandtheabilitytosteriliseandimprovethequalitycontrolofeverysingleseal.
• TheFrameSealTMalsoenablestheuseofsheetedsealingmaterialinautomation.
NEW
COMING SOON
www.4ti.co.uk | 75 +44 (0)1306 884885 www.4ti.co.uk | 75 +44 (0)1306 884885