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Chemoselective Hydrogenation of Nitro Compounds with Supported Gold Catalysts
Avelino Corma* and Pedro Serna
Science 2006, 313, 332-334
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R N
O
O
MLn + H2
LnM H
H
oxidative addition
N
O
OR
MLn-1
migratory insertionNH
O
OR N
O
Relimination
-L
nitrosyl
Ln-1M H
OH
N
O
R
migratory insertionNH
O
R
H
H
MLn-1
H
Ln-1M
H
OH
Ln-1M H
OH
MLn-1
OH
LnM H
H
N
O MLn-1
OHLnMH
H R
H
sigma-metathesisNH2R + O MLn-1
OH
LnM
H
N
O
R
reductive elimination
HO MLn-1
OHMLn
+
reductive elimination+L
MLn + H2O2
Mechanism
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