ALCOHOL
Chapter 8
PRODUCTION OF ALCOHOL
Anaerobic condition CO2
Glucose Pyruvate Acetaldehyde Fermentation of yeast
PRODUCTION OF ALCOHOL
Acetaldehyde
NADH
NAD+
Ethanol
ENERGY CONTENT OF COMMON ALCOHOLIC
BEVERAGES
Alcohol Metabolism
DIGESTION AND ABSORPTION OF
ALCOHOL No digestion required
Absorbed by simple diffusion and moves directly into blood stream
No specific mechanism required to enter body cells
Alcohol damages cell membrane proteins as it enters body cells.
ALCOHOL METABOLISM
ALCOHOL METABOLISM
ALCOHOL METABOLISM
Catalase Found in the liver Minor pathway for alcohol
metabolism
Catalase H2O2 H2O
Ethanol Acetaldehyde
What to do with Acetaldehyde?
Acetaldehyde dehydrogenase
Acetyl CoA is non-toxic to body cells
Fate of Acetyl-CoA
CO2 + H2OAcetyl-CoA Fatty Acid
Glucose
Moderate Alcohol Consumption Versus Alcohol
Abuse
Benefits and Problems
Problems Associated with Alcohol Abuse
Increases 5 of the top 10 causes of death in the U.S.
Cirrhosis of the liver
Inflammation of stomach and pancreas
Hypertension and hemorrhagic stroke
Problems Associated with Alcohol Abuse
Brain damage and neurotransmitter imbalances
Myocardial depression and Arrhythmias
Cardiomyopathy
Fetal Alcohol Syndrome