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Dr Vaughan Langford
Real-Time Monitoring of Hazardous Air
Pollutants in the Semic onduc torManufac turing Environment Using SIFT-MS
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Semic onduc tor IndustryApplications of SIFT-MS
Princ ip les of SIFT-MS
Ana lysis c apab ilities
Air qua lity monito ring
using SIFT-MS
Key benefits of theVoice200 instrument
Conc lud ing remarks
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Princ iples of theSIFT-MS Tec hnique
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What is SIFT-MS?
Selec ted Ion Flow Tube MassSpec trometry (SIFT-MS) is a form of d irec tmass spec trometry tha t utilizes precisely
c ontrolled c hemic a l ioniza tion reac tions. SIFT-MS detec ts and qua ntifies trac e
amounts of d iverse vo la tile organic
c ompounds (VOCs) and c erta ininorganic gases
from whole a ir
in real time
with typ ic a l detec tion limits atparts-per-trillion level (by volume)
in a single, convenient analysis
The Syft Tec hnolog iesVoice200
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SIFT-MS princ ip les
SI FT MS
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SIFT-MS CI compared withGC-MS CI and EI ionization
SIFT-MS uses muc h softer CI agents than GC-MS(c a lled reagent ions in SIFT-MS)
This results in significantly less fragmenta tion
than EI ioniza tion and CI, makingc hromatography unnec essary and rea l-timeana lysis possib le
As a c onseq uence, the c ompound fingerp rint for SIFT-MS will genera lly be lessspec ific than in GC-MS
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Ethylbenzene using EI and CI (O2+)
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Relative
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tensity/%
Elec tron impac tioniza tion (70 eV)
Chemic a l ioniza tion:O2
+ reagent (12.1 eV)
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Resolving acetone and propanal
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Branchingratio/%
NO+
O2+
H3O+
SIFT-MS is ab le to resolve c erta inisobaric and isomeric c ompounds.
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Analysis Capabilities ofthe SIFT-MS Tec hnique
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What types of samples c an
SIFT-MS analyze?
SIFT-MS is a ded ic a ted ana lyzer fortrac e reac tive c ompounds in a ir
Dry or humid whole a ir samp les:
Outdoor/ indoor a ir Breath
Headspac e above aq ueous
solutions or solids
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Sample presentation to SIFT-MS
A range o f sampling methods
are c ompatib le with SIFT-MSwhole a ir ana lysis:
Direc t live sampling ofwhole a ir
Gas sampling bags (e.g.Ted la r, Teflon)
SUMMA c anisters
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What compounds c an SIFT-MS ana lyze?
General c lass Example c lasses / c ompounds
hyd roc arbons a lkanes, a lkenes, a romatic s
oxygena tes a lc ohols, a ldehydes, ketones, esters
nitrogen compounds amines, amides, nitriles
sulfur c ompounds merc ap tans, thioethers, c a rbonyl sulfide
halog ena ted c ompounds freons, perfluoroc arbons, a liphatic and
aromatic fluorides and c hlorides, etc .organosilic on c mpds siloxanes, silanes
organophosphoruscompounds
organophosphates, organophosphites
inorganic c ompounds ammonia , c hlorine, hydrogen sulfide,phosphine, selec ted inorganic ac idsand b oron c omp ounds
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The Voice200as a Tool forAir Quality Monitoring
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Why SIFT-MS? The c apab ilities of SIFT-MS make it
an idea l solution for p rotec ting:
Worker hea lth
Produc t qua lity
The environment
Relevant ind ustries inc lud e:
Semic onduc tor fab ric a tion
LED panel manufac ture Sola r c ell fab ric a tion
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Real-Time AirMonitoring
The graphs show results for
butadiene for two p rod uc tions:
linearity (above)
ambient a ir ana lysis a t theSyft hea d offic e(Christc hurc h, NewZealand).
0.5
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0.1
0.0
Concentration
(pp
bv)
18:00
9/2/09
0:00
9/3/09
6:00
Measurement data and time
1,3-butadiene, NO+, C4H6+
1,3-butadiene, O2+, C4H6+
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Stac k Emission Analysis
Ab ility to monitor stac k
emissions d irec tly in stac kvia a suita b le samplingarrangement
Unique flexib ility of SIFT-MSa lso enab les the sameinstrument to makemeasurements a t siteboundary
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Fumigants
Toxic industria lchemicals
Oc cupational Safety and Health
Fast, simp le, ac c ura te and ec onomic a l
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All c onta iner fumigants a re ha rmful tohumans
Some a re letha l a t very low levels Conta iners may have a far la rger dose
of fumigant app lied than isrecommended
Residua l fumigants c rea te a hazard forworkers entering the c onta iners
Employers ha ve a lega l responsib ility to
p rotec t workers.
Example of detec tion of toxic
compounds: fumigants
Methyl bromideChloropicrin
Hydrogen cyanide
Ethylene oxide
Phosphine
Sulfuryl fluoride
Ethylene dibromide
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Robust design
Solvent-free
Cheap to run
Very fast (typ ic a lly 1 minute persample)
Simp le to opera te (touc h sc reen)
Repeatab le ana lytic a l-grade results
The Syft solution-based approac h
Results d isplayed on theVoice200 instrument
Samplecase
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Key Benefits of theVoice200 Instrument
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Syft Voice200automation and
remote acc ess
The Voic e200continually
monitors its own performanc e Fully automated va lida tion
c yc les (usua lly done once per
day) ensure tha t ana lysis isvalid
The Voic e200 is network-
ready c an be op era ted fromany loc a tion with internetaccess
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Syft Voice200durability and mobility
Syft s instruments a reinsta lled in industria lapp lic a tions (suc h as inwarehouses and vans*),as well as in labora tories
Within a fac ility, they are
easily maneuvered usingtheir built-in wheels
* The instrument c an ob ta inquantita tive da ta 15minutes a fter being movedto another loc a tion!
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Software: Voice200 instrument
Designed for use by non-tec hnic a l op era tors
The Voic e 200 instrumentssoftware has severa l p rimaryfunctions:
Controlling the instrument
Valida ting that theinstrument is opera tingwithin spec ific a tion
Running methods toana lyze samples; c omputeand p resent results
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Software: LabSyft
The Syft LabSyft softwarepac kage op era tes on a remote
c omputer and is designed foradvanced users
LabSyft a llows users to:
View data as it is genera ted
View and manipula te da ta a ftersc an c omp letion
View, searc h and expand the
c ompound lib ra ry Crea te and ed it analytic a l
methods
Set up ba tc h ana lyses
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Conc luding Remarks
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Benefits of Syft SIFT-MS technology
Sensitive , rea l-time ana lysis withoutpreconcentration
Diverse c hemic a ls c an be ana lyzedin a sing le run c ustomized to meetc ustomers needs
Mobile with rap id sta rt-up
Simp le opera tion
Low ma intenance and lowopera ting c osts
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Why c hoose SIFT-MS over GC-MS?
Read ily configured for use by non-tec hnic a lpeop le ( user friend ly )
Red uced ma intenance Get labora tory-grade ana lyses faster bec ause
Chromatography is eliminated
Minimal or no samp le p repara tion is required
Long-term c a lib ra tion stab ility b ec ause
Prec ise ioniza tion c ontrol is used
There is no chromatographic c olumn
The ion sourc e and detec tion system is very c lean
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Thank you for your a ttention.
For more information:see us a t booth 1314,visit our website www.syft.com ,
e-ma il us a t [email protected] ,or c onta c t our Ta iwanese d istributor:
Integrated Sc ientific Servic es Group
Web: www.issg.c om.twPhone: (02)8797 7272