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XII INTERNATIONAL WORKSHOP OF LOWER GENITAL TRACT PATHOLOGY HPV diseases and cervical cancer: taking stock of the present and planning for the future. Rome 5-7 March 2015 Course Directors A. Frega, Italy C. Gentili, Italy P. Davies, Belgium ORGANIZING SECRETARIAT Triumph Italy S.r.l. Via Lucilio 60 - 00136 Rome Phone: +39 06 35530 382 Fax: +39 06 35530 262 [email protected] www.hpv2015rome.com Provider n. 712 Triumph ECM S.r.l. Via Lucilio, 60 - 00136 Rome Ecm

XII INTERNATIONAL WORKSHOP OF LOWER GENITAL TRACT … · LOWER GENITAL TRACT PATHOLOGY HPV diseases and cervical cancer: taking stock of the present and planning for the future. Rome

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Page 1: XII INTERNATIONAL WORKSHOP OF LOWER GENITAL TRACT … · LOWER GENITAL TRACT PATHOLOGY HPV diseases and cervical cancer: taking stock of the present and planning for the future. Rome

XII INTERNATIONALWORKSHOP OFLOWER GENITALTRACT PATHOLOGY

HPV diseases and cervical cancer:taking stock of the present andplanning for the future.

Rome 5-7 March 2015Course DirectorsA. Frega, ItalyC. Gentili, ItalyP. Davies, Belgium

ORGANIZING SECRETARIATTriumph Italy S.r.l.Via Lucilio 60 - 00136 RomePhone: +39 06 35530 382Fax: +39 06 35530 [email protected]

Provider n. 712

Triumph ECM S.r.l.Via Lucilio, 60 - 00136 Rome

Ecm

Page 2: XII INTERNATIONAL WORKSHOP OF LOWER GENITAL TRACT … · LOWER GENITAL TRACT PATHOLOGY HPV diseases and cervical cancer: taking stock of the present and planning for the future. Rome

Patronages Thursday 5 March

European Cervical Cancer Association

07:45 - 08:15 REGISTRATION

11:00 - 11:30 BREAK BREAK

13:00 - 14:30 LUNCH LUNCH

HPV disease of the HPV disease of the lower genital tract for lower genital tract

gynaecologists. for pathologists. First part First part

16:25 - 16:45 BREAK BREAK

ROOM A ROOM B

08:15 - 08:30 Welcome

08:30 - 09:00 HPV infection and cervical cancer

Cervical screening around 09:00 - 11:00 the world. Current status

and key challenges

Free communications

11:30 - 13:00 Challenges in Freecervical screening communications

14:30 - 16:25 Vaccination. Molecular tests in Part one the cytopathology lab

17:40 - 18:35 Challenging situations New issues 17:55 - 18:35 in colposcopy in cytophology

16:45 - 17:40 New frontiers in 16:45 - 17:55 colposcopy Liquid-based cytology

18:35 - 18:53 Twitter session Twitter sessionN

on-E

CM

Ses

sion

sEC

M C

ours

es3

With the Patronage of Italian Health Ministry

Page 3: XII INTERNATIONAL WORKSHOP OF LOWER GENITAL TRACT … · LOWER GENITAL TRACT PATHOLOGY HPV diseases and cervical cancer: taking stock of the present and planning for the future. Rome

Saturday 7 March

ECM

Cou

rses

Non

-EC

M S

essi

ons

10:30 - 10:45 BREAK BREAK

HPV disease of the HPV disease of the lower genital tract for lower genital tract

gynaecologists. for pathologists. Third part Third part

ROOM A ROOM B

08:30 - 10:00 Atelier de travail Atelier de travail

10:00 - 10:30 Issues in clinic Focus on glandular lesions

12:00 - 12:45 Awards and conclusions

13:15 - 13:30 Closing ceremony

12:45 - 13:15 HPV disease: conclusions in twitter style

Friday 6 March

Non

-EC

M S

essi

ons

ECM

Cou

rses

10:00 - 10:30 BREAK BREAK

13:00 - 14:15 LUNCH LUNCH

HPV disease of the HPV disease of the lower genital tract for lower genital tract

gynaecologists. for pathologists. Second part Second part

ROOM A ROOM B

08:30 - 10:00 Clinical and pathology perspectives.

The actors speak. Part one

10:30 - 13:00 Clinical and pathology perspectives.

The actors speak. Part two

15:15 - 16:15 Management of CIN Pap-smear: never say never again

16:15 - 16:45 BREAK BREAK

Freecommunications

Freecommunications

11:45 - 12:00 ECM TEST ECM TEST

16:45 - 17:15 Issues in colposcopy Diagnosis in 16:45 - 17:45 cytopathology

17:15 - 18:3017:45 - 18:30 Multifocal diseases Legal questions

18:30 - 18:54 Twitter session Twitter session

10:45 - 11:45 Training in Training in colposcopy cytopathology

14:15 - 15:15 Vaccination. Classifications and Part two quality control in

cervical cytopathology

54

Page 4: XII INTERNATIONAL WORKSHOP OF LOWER GENITAL TRACT … · LOWER GENITAL TRACT PATHOLOGY HPV diseases and cervical cancer: taking stock of the present and planning for the future. Rome

Thursday 5 March Thursday 5 MarchROOM A

08:15-08:30 WELCOMEA. Frega, C. Gentili

PLENARY SESSION

08:30-09:00 HPV INFECTION AND CERVICAL CANCERA. Frega, C. Gentili

08:30-08:45 The natural history of HPV infection: “What’s happening, brother?”M.T. Goodman

08:45-09:00 What do the natural history studies tell us about the mechanisms of progression vs regression and does this help clinical decision-making? B. Moscicki

09:00-11:00 CERVICAL SCREENING AROUND THE WORLD. CURRENT STATUS AND KEY CHALLENGESP. Davies, P. Giorgi Rossi

Cervical screening outside of Europe09:00-09:15 North America

R. Nayar09:15-09:30 South America

S. Tatti09:30-09:45 Asia

R. Sankaranarayanan09:45-10:00 Australasia

M. Saville

Cervical screening in Europe and the Caucasus10:00-10:20 Western Europe

H. Sancho-Garnier10:20-10:40 Eastern Europe

D. Valuta10:40-11:00 The Caucasus

T. Khomasuridze

11:00-11:30 BREAK

11:30-13:00 CHALLENGES IN CERVICAL SCREENINGL. Mariani, S. Tatti

11:30-11:45 Encouraging countries to move from opportunistic to organised screeningP. Davies

11:45-12:00 The introduction of HPV testing for primary screening. Feedback fromthe first organised programmes N. Van der Veen

12:00-12:15 Can self-sampling improve screening efficacy among populations with low-screening attendance? H. Sancho-Garnier 76

12:15-12:30 Screening vaccinated populations. As disease rates decline, when willscreening cause more harm than good? P. Nieminen

12:30-12:45 HPV RNA testing: can it improve the screening algorithm? K.U. Petry

12:45-13:00 DISCUSSION

13:00-14:30 LUNCH

ROOM A

ECM COURSE: HPV DISEASE OF THE LOWER GENITAL TRACT FOR GYNAECOLOGISTS. FIRST PART

14:30-16:25 VACCINATION. PART ONEA. Lukic, J. Paavonen

HPV vaccination around the world. The programmes, the coverage and the challenges

14:30-14:42 Europe and the Caucasus D. Valuta

14:42-14:54 North America R. Nayar

14:54-15:06 South America S. Tatti

15:06-15:18 Asia R. Sankaranarayanan

15:18-15:30 Australasia M. Saville

15:30-15:45 Planning a successful HPV vaccination launch: the key elements for successJ. Dillner

15:45-16:00 HPV vaccination implementation case study: the Dutch experienceM. Conyn-van Spaendonck

16:00-16:15 Vaccination: so how long does the protection really last?J. Dillner

16:15-16:25 DISCUSSION

16:25-16:45 BREAK

16:45-17:40 NEW FRONTIERS IN COLPOSCOPYK.U. Petry, F. Sesti

16:45-17:00 Colposcopy and HPV primary screening: clinical considerations P. Walker

17:00-17:15 Colposcopy in vaccinated populations: how to maintain performanceas disease rates decline J. Paavonen

17:15-17:30 The use of HPV-related biomarkers in different clinical applications M. Kyrgiou

17:30-17:40 DISCUSSION

Page 5: XII INTERNATIONAL WORKSHOP OF LOWER GENITAL TRACT … · LOWER GENITAL TRACT PATHOLOGY HPV diseases and cervical cancer: taking stock of the present and planning for the future. Rome

Thursday 5 March09:40-11:00 MOLECULAR AND MORPHOLOGIST DIAGNOSIS

M.R. Giovagnoli, O. Nappi

09:40-09:50 P16INK4a/ki-67 detection in ASC-US and ASC-H cytology with HR-HPV DNA positive test and in corresponding histological sample:preliminary dataT. Addati, R. Nenna, D. Di Clemete, V. Losito, L. Vurchio, A. De Lucia,G. Elicio, P. Miscioscia, A. Belsanti, C.D. Inchingolo

09:50-10:00 Cervical Glandular Neoplasia and its look-a-like S. Rahimi, S. Kenward, I. Akaev, S. Votano

10:00-10:10 Incidence of HR HPV and histological alterations in Pap-test with ASC-USA. Berjawi Charour, N. Prats Montejano, G. Valdelvira Riego, M. Alsina Hipólito, Echavarría Ramos María del Carmen, E. Rodero Salgueiro

10:10-10:20 p16/Ki67 dual immunocytochemical staining implementation in threecytopathology laboratories participating in Slovenian cervical cancerscreening program ZORA V. Kloboves Prevodnik, U. Ivanuš, A. Repše Fokter, S. Hutter Celik, S. Jezeršek, U. Klopcic, Ž. Pohar Marinšek, K. Gornik Kramberger, N. Nolde, S. Uhan Kastelic, J. Zalar, M. Lešnjak, M. Fras, N. Irgel, B. Jelen, B. Antolovic, P. Pernat, L. Salobir, K. Seher Ana, N. Štiglic Toš, M. Primic Žakelj, M. Marcec, M. Pakiž, T. Kodric, U. Salobir Gajšek, J. Koren, I. Takac, M. Florjancic, T. Jerman

10:20-10:30 Comparative evaluation of RNA and DNA approach for HPV diagnosisM. Piovan, A. Apolloni, T. Bartolotti, C. Lapucci

10:30-10:40 Novel flow cytometry-based assay for detection of E6/E7 mRNA in cervical and anal specimensM. Mira, J. Coleman, D. Schapfel

10:40-10:50 Validation of in-house liquid based medium for HPV detection with Hybrid Capture 2N. Nolde, S. Uhan Kastelic, V. Kloboves Prevodnik, Ž. Pohar Marinšek,U. Ivanuš, M. Primic-Žakelj, M. Marcec, M. Pakiž, T. Kodric,U. Salobir Gajšek, J. Koren, A. Repše Fokter, I. Takac, S. Šramek Zatler, R. Kavalar, B. Grcar Kuzmanov, M. Florjancic, T. Jerman Tine

10:50-11:00 Assessment of Pap-smear qualitySakonlaya Dussadee, Yanagihara Luckakul

11:00-11:30 BREAK

11:30-11:50 MOLECULAR AND MORPHOLOGIST DIAGNOSISS. Votano, A. Frega

11:30-11:40 Non Hodgkin Lymphoma some features on the Pap-smearC. Bosco, A. Chiarugi, S. Cuccato, P. Viacava

11:40-11:50 HPV-mRNA test and multiple intraepithelial neoplasias of the femalelower genital tractG.N. Milazzo, A. Catalano, D. French, D. Caserta

98

Thursday 5 March17:40-18:35 CHALLENGING SITUATIONS IN COLPOSCOPY

A. Biamonti, P. Walker

17:40-17:55 Colposcopy in pregnancy: balancing the risk of pregnancy loss againstcancer development S. Dexeus

17:55-18:10 Colposcopy in menopause: challenges and solutions K.U. Petry

18:10-18:25 Colposcopy: do we need more evidence-based training, standards andQA or just random biopsies? W. Prendiville

18:25-18:35 DISCUSSION

18:35-18:53 TWITTER SESSIONF. Sesti, A. Lukic

18:35-18:41 Vaccination. Part oneJ. Dillner

18:41-18:47 New frontiers in colposcopyK.U. Petry

18:47-18:53 Challenging situations in colposcopyP. Walker

ROOM B

FREE COMMUNICATIONS

08:30-09:40 CERVICAL CANCER AND HPVD. French, A. Venuti

08:30-08:40 Autophagy is down-regulated by the E5 protein of human papillomavirus 16M. Nanni, F. Belleudi, S. Raffa, M.R. Torrisi

08:40-08:50 Epithelial target cell and the development of cervical disease - currentthinking and observationsR. Olaf, R. Sigrid

08:50-09:00 MicroRNA 551-b expression profile in cervical intraepithelial lesions M. Di Properzio, E. Carico, R. Mancini, C. De Vitis, S. Giglio, A. Noto, M.R. Giovagnoli, M. Moscarini, D. Caserta, A. Lukic

09:00-09:10 HPV16 E5 as target of immunotherapy F. Paolinii, M. Nazario Cordeiro, R. de Cássia Pereira de Lima, G. Curzio, A.C. de Freitas, A. Venuti

09:10-09:20 Human Papilloma Virus infection and his correlation with feminal parametersN. Grieco, M.A. Di Filippo, T. Notari, G. D’Aniello, S. Ronsini

09:20-09:30 The sumo conjugating enzyme ubc9 as a biomarker for cervical HPVinfectionsC. Casadio, D. Mattoscio, M. Fumagalli, M. Sideri, S. Chiocca

09:30-09:40 New prospect in HPV infection therapy P. Eid

Page 6: XII INTERNATIONAL WORKSHOP OF LOWER GENITAL TRACT … · LOWER GENITAL TRACT PATHOLOGY HPV diseases and cervical cancer: taking stock of the present and planning for the future. Rome

Thursday 5 March Thursday 5 March15:00-15:15 HPV typing: do we know enough to base clinical decisions on HPV type

(… or would we treat a woman with HPV 16 differently from a womanwith HPV 33)? K.U. Petry

15:15-15:30 HPV E5 oncoprotein: possible role in L-SIL progression A. Venuti

15:30-15:45 Molecular bio-banking: a resource for research L. Dillner

15:45-16:00 What has changed in cytopathologist's report? M. Desai

16:00-16:25 DISCUSSION

16:25-16:45 BREAK

16:45-17:55 LIQUID-BASED CYTOLOGYC. Bergeron, G. Negri

16:45-17:15 The traditional Pap-test vs LBC. Two advocates present their cases L. Di Bonito, R. Nayar

17:15-17:30 LBC: a comparison of the systems M. Desai

17:30-17:45 Automation: can we afford it in these times of austerity?M. Saville

17:45-17:55 DISCUSSION

17:55-18:35 NEW ISSUES IN CYTOPATHOLOGYM. Benevolo, M. Desai

17:55-18:05 The Bethesda 2014 update: what's new? R. Nayar

18:05-18:20 Cytology and HPV testing in the prevention of anal cancer T.M. Darragh

18:20-18:35 DISCUSSION

18:35-18:53 TWITTER SESSIONL. Di Bonito

18:35-18:41 Molecular tests in the cytopathology labL. Dillner

18:41-18:47 LBCG. Negri

18:47-18:53 New issues in cytopathologyM. Saville

1110

11:50-12:40 EPIDEMIOLOGY, SCREENING AND PROGNOSTIC FACTORSG. Petricone, M. Benevolo

11:50-12:00 HPV multple infections, viral load and integration status: prognostic factors in secondary screening of cervical cancer L. Bianchi, S. Donati, Z. Napoli, M. Donati, A. Cafissi, M. Niccolai, R. Lari

12:00-12:10 Primary HPV test in cervical cancer screening in local health unit of Latina (Italy)C. Chiapetta, E. Lendaro, J. Cacciotti, G. Migliore, P. Bellaridini, N. Porta, V. Petrozza, C. Della Rocca, C. Di Cristofano

12:10-12:20 The 16, 18 and 45 HPV infection triage in primary HR-HPV test screening program in local health unit of Latina (Italy)C. Chiappetta, E. Lendaro, J. Cacciotti, R. Zaralli, C. Puggioni, G. Migliore, V. Petrozza, C. Della Rocca, C. Di Cristofano

12:20-12:30 Cervical cancer screening and cervical excisional treatment among women aged below 25 years between 2007 and 2013 in France I. Heard, C. Chaignot, G. Maura, A. Weill, F. Alla, P. Ricordeau

12:30-12:40 Cervical CancerÖ. Nöoeighöowa

12:40-13:10 EDUCATION AND AWARENESSA. Lukic, P. Scirpa

12:40-12:50 Perception about cervical cancer prevention of daughters in Korean mothersK.Hae Won

12:50-13:00 Primary prevention of HPV infection for adolescents L. Dubravko

13:00-13:10 Mediation effects of fear of cancer recurrence on cancer distress andquality of life in cervical cancer patientsT. Shiow-Luan, H. Chia-Ching

13:10-14:30 LUNCH

ROOM B

ECM COURSE: HPV DISEASE OF THE LOWER GENITAL TRACT FOR PATHOLOGISTS. FIRST PART

14:30-16:25 MOLECULAR TESTS IN THE CYTOPATHOLOGY LABT.M. Darragh, D. French

14:30-14:45 Getting around in molecular testing jungle: what clinicians and pathologists should know to properly interpret the results L. Dillner

14:45-15:00 Molecular tests: which tests are ready for clinical use and what do they add to clinical algorithms? M. Kyrgiou

Page 7: XII INTERNATIONAL WORKSHOP OF LOWER GENITAL TRACT … · LOWER GENITAL TRACT PATHOLOGY HPV diseases and cervical cancer: taking stock of the present and planning for the future. Rome

Friday 6 MarchROOM A

PLENARY SESSION

08:30-10:00 CLINICAL AND PATHOLOGY PERSPECTIVES. THE ACTORS SPEAK. PART ONEA. Biamonti, G.L. Taddei

Cervical cytology or the molecular model: which is the best way forward?

08:30-08:40 Clinical perspective P. Nieminen

08:40-08:50 Cytopathology perspective R. Nayar

08:50-09:00 OPEN DISCUSSION

ASC-US and AGC: can we get over this deadlock?09:00-09:10 Clinical perspective

P. Walker09:10-09:20 Cytopathology perspective

G. Negri09:20-09:30 OPEN DISCUSSION

CIN 2. Where are we now: do we treat it or not? 09:30-09:40 Clinical perspective

B. Moscicki09:40-09:50 Cytopathology perspective

T.M. Darragh09:50-10:00 OPEN DISCUSSION

10:00-10:30 BREAK

10:30-13:00 CLINICAL AND PATHOLOGY PERSPECTIVES. THE ACTORS SPEAK. PART TWOA. Lukic, G.L.Taddei

Persistently HPV positive but cytology and colposcopy negative: what are the clinical recommendations?

10:30-10:40 Cytopathology perspective M. Saville

10:40-10:50 Clinical perspective W. Prendiville

10:50-11:00 OPEN DISCUSSION

HSIL but clinically normal: who is wrong? 11:00-11:10 Cytopathology perspective

M. Desai11:10-11:20 Clinical perspective

K.U. Petry11:20-11:30 OPEN DISCUSSION

Combining molecular tests: can this improve clinical decisions?11:30-11:40 Cytopathology perspective

C. Bergeron

Friday 6 March

1312

11:40-11:50 Clinical perspective M. Kyrgiou

11:50-12:00 OPEN DISCUSSION

What can and can’t the pathologist say to clinician and the clinician to the pathologist?

12:00-12:10 Cytopathology perspective L. Di Bonito

12:10-12:20 Clinical perspective S. Dexeus

12:20-12:30 OPEN DISCUSSION

Revised terminology for cervical histopathology and its implicationsfor management of HSIL

12:30-12:40 Pathology perspective T.M. Darragh

12:40-12:50 Clinical perspective S. Tatti

12:50-13:00 OPEN DISCUSSION

13:00-14:15 LUNCH

ROOM A

ECM COURSE: HPV DISEASE OF THE LOWER GENITAL TRACT FOR GYNAECOLOGISTS. SECOND PART

14:15-15:15 VACCINATION. PART TWOR. De Vincenzo, E. Siegler

14:15-14:30 HPV vaccination: three doses, two doses or just one? R. Sankaranarayanan

14:30-14:45 What is the most cost-effective target population? Girls? Boys? Women? Men? Everybody? J. Dillner

14:45-15:00 New developments in HPV vaccination: what do we know about the nonavalent vaccine? J. Paavonen

15:00-15:15 DISCUSSION

15:15-16:15 MANAGEMENT OF CINB. Moscicki, P. Scirpa

15:15-15:30 Clinical guidelines vs. clinical judgement: where do you draw the line?P. Walker

15:30-15:45 Treating CIN during pregnancy: key criteria and treatment options E. Siegler

15:45-16:00 Treating recurrent CIN while preserving fertility in the nulliparous younger womanM. Kyrgiou

16:00-16:15 DISCUSSION

Page 8: XII INTERNATIONAL WORKSHOP OF LOWER GENITAL TRACT … · LOWER GENITAL TRACT PATHOLOGY HPV diseases and cervical cancer: taking stock of the present and planning for the future. Rome

Friday 6 March Friday 6 March09:00-09:10 Measurement of Quality of Colposcopy within cervical screening in

Europe-Quality Assurance of Colposcopy Italian Network (QuACINet)C. Carriero, S. Leeson, F. Boselli

09:10-09:20 Fertility and early pregnancy outcomes after treatment for cervical intra-epithelial neoplasia: a systematic review and meta-analysis of the literatureM. Kyrgiou, A. Mitra, M. Arbyn, S.M. Stasinou, P. Martin-Hirsch, P. Bennett, E. Paraskevadis

09:20-09:30 Management of patients with cytological low-grade or borderline abnormalities: how powerful is a negative colposcopy? C. Ricci, M. Martin, K. Neenan, W. Prendiville

09:30-09:40 A case of AIS in pregnancy M.T. Evangelista, M.R. Primieri, C. Ricci, I.N. Trivellizzi, C. Conte,R. De Vincenzo, G. Scambia, P. Scirpa

09:40-09:50 A case of pregnancy after treatment for IA2 cervical cancer M.T. Evangelista, M.R. Primieri, C. Ricci, I.N. Trivellizzi, C. Conte,R. De Vincenzo, G. Scambia, P. Scirpa

10:00-10:30 BREAK

10:30-10:50 HPV TESTING AND VACCINATIOND. French, A. Biamonti

10:30-10:40 Cyto-colposcopic follow-up of an HPV vaccinated cohort of women inItaly: what should we expect in real life? R. De Vincenzo, C. Conte, N.I. Trivellizzi, C. Ricci, M.T. Evangelista, M.R. Primieri, P. Scirpa, G. Scambia

10:40-10:50 Speranza study: preliminary results of HPV vaccination after loop electrosurgical excision procedure for cervical intraepithelial neoplasia A. Ghelardi

10:50-12:00 CERVICAL CANCER PREVENTION IN LOW-RESOURCES SETTINGSR. Sankaranarayanan, A. Venuti

10:50-11:00 Prevalence of human papilloma virus infection and cervical pre cancerlesions among female sex workers in Mumbai, IndiaP. Sharmila, M. Gauravi, S. Surendra

11:00-11:10 Development of HPV PCR assay in menstrual pad for rural Indian Women: Pilot study data. Experience while standardizing method P. Vrushali, B. Atul, M. Perveen, L. Manoj, M. Amita, P. NS, P. Palllavi, D. Rajesh, V. Ashok

11:10-11:20 Cervical cancer screening in Madagascar: usability of mobile telemedicine for detection of precancerous lesions from smartphonephotosR. Catarino, D. Ricard-Gauthier, J.C. Matute, U. Meyer-Hamme, M. Undurraga, S. Scariengella, J. Jinoro, P. Vassilakos, P. Petignat

11:30-11:40 Comparative evaluation of Hybrid Capture 2 and cytology as triage tests among VIA/ VILI screen positive womenM. Gauravi, S. Surendra, K. Sheetal

1514

16:15-16:45 BREAK

16:45-17:15 ISSUES IN COLPOSCOPYM. Kyrgiou, C. Zanardi

16:45-17:00 Cervical cancer after CIN treatment: wrong diagnosis, inadequate therapy or just bad luck? W. Prendiville

17:00-17:15 What are the medical-legal risks in colposcopy and who are the bestmedical defence lawyers in each country? P. Walker

17:15-18:30 MULTIFOCAL DISEASESA. Biamonti, S. Dexeus

17:15-17:30 Multifocal lesions: how and why do they occur?M.T. Goodman

17:30-17:45 VIN HPV relatedL. Micheletti

17:45-18:15 Anal intraepithelial lesions in women with HPV-related disease S. Tatti

18:15-18:30 DISCUSSION

18:30-18:54 TWITTER SESSIONM. Kyrgiou, L. Mariani

18:30-18:36 HPV vaccination. Part twoL. Dillner

18:36-18:42 Management of CINE. Siegler

18:42-18:48 Issues in colposcopyS. Dexeus

18:48-18:54 Multifocal diseasesM.T. Goodman

ROOM BFREE COMMUNICATIONS

08:30-09:50 COLPOSCOPYF. Sesti, R. De Vincenzo

08:30-08:40 Chemotherapy in pregnant women with cervical cancer: a single institution experience C. Ricci, I.N.Trivellizzi, C. Conte, G. Scambia, R. De Vincenzo

08:40-08:50 HPV-positive patients with the CIN relapse -further procedure and treatment R. Živadinovic, A. Petric, D. Krtinic

08:50-09:00 “See and treat” strategy for HSIL: correlation between colposcopy and histopathologyC. Dragosloveanu, R. Vladareanu

Page 9: XII INTERNATIONAL WORKSHOP OF LOWER GENITAL TRACT … · LOWER GENITAL TRACT PATHOLOGY HPV diseases and cervical cancer: taking stock of the present and planning for the future. Rome

Friday 6 March Friday 6 March

1716

15:45-16:00 What molecular biology cannot provide G. Negri

16:00-16:15 DISCUSSION

16:15-16:45 BREAK

16:45-17:45 DIAGNOSIS IN CYTOPATHOLOGYL. Di Bonito, T.M. Darragh

16:45-17:00 Cytology accuracy: can more training compensate for time constraints? M. Saville

17:00-17:15 Cytology during pregnancy: does it need to be interpreted differentlydepending on the stage of pregnancy? M. Desai

17:15-17:30 Cytology in menopause: challenge for the pathologist G. Negri

17:30-17:45 DISCUSSION

17:45-18:30 LEGAL QUESTIONSG. Negri, M. Saville

17:45-18:00 Over-diagnosis in cytopathology: is the histology the gold standard? T.M. Darragh

18:00-18:15 Legal questions in the lab with the new molecular algorithms R. Nayar

18:15-18:30 DISCUSSION

18:30-18:54 TWITTER SESSIONM. Benevolo, T.M. Darragh

18:30-18:36 Classifications and quality control in cervical cytopathologyC. Bergeron

18:36-18:42 Pap-smear: never say never againG. Negri

18:42-18:48 Diagnosis in cytopathologyL. Di Bonito

18:48-18:54 Legal issues for the cytopathologistM. Desai

11:40-11:50 Population based screenings for cervical cancer: cost effective approach in low resource setting using high end methodology in triaging algorithm and genomic integrations N. Manu, A. Maninder

11:50-12:00 Chemopreventive effects of curcumin on cervical cancers and precancerous cellsS. Dusadee, T. Pirath, P. Auragun, C. Saengsoon

12:00-12:40 MISCELLANEOUSM.T. Goodman, R. Senatori

12:00-12:10 Characterization of the vaginal microbiome in women with cervical intraepithelial neoplasia A. Mitra, D. MacIntyre, L. Yun, A. Smith, J. Marchesi, E. Holmes, J. Nicholson, P. Bennett, M. Kyrgiou

12:10-12:20 Impact of Sexually Transmitted Diseases in pregnancy: knowledge ofpregnant women C. Caixeta

12:20-12:30 Rare genitourinary anomalies M. Fahmy

12:30-12:40 Prevalence of co-infections with human papillomavirus and mycoplasma/ureaplasma species in women with abnormal cervical cytologyJi Yong Il

13:00-14:15 LUNCH

ROOM B

ECM COURSE: HPV DISEASE OF THE LOWER GENITAL TRACT FOR PATHOLOGISTS. SECOND PART

14:15-15:15 CLASSIFICATIONS AND QUALITY CONTROL IN CERVICAL CYTOPATHOLOGYG. Negri, M. Saville

14:15-14:35 Cervical cytology specimen adequacy: patient management guidelinesand optimizing specimen collection C. Bergeron

14:35-14:55 Quality control in cervical cytology: can we exploit the biomarkers? M. Desai

14:55-15:15 DISCUSSION

15:15-16:15 PAP-SMEAR: NEVER SAY NEVER AGAINR. Nayar, A. Venuti

15:15-15:30 Cervical cytology: can it survive in the era of HPV vaccination? C. Bergeron

15:30-15:45 Why East European countries should still devote resources to the Pap-smearP. Davies

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Saturday 7 March Saturday 7 March

1918

ROOM A

ECM COURSE: HPV DISEASE OF THE LOWER GENITAL TRACT FOR GYNAECOLOGISTS. THIRD PART

08:30-10:00 ATELIER DE TRAVAILG. Petricone, P. Stentella

Video interactive session on colposcopy coordinated by Walter PrendivilleM. Barbero, A. Biamonti, S. Dexeus, K.U.Petry, S. Tatti, P. Nieminen

10:00-10:30 ISSUES IN CLINICC. Carriero, S. Votano

10:00-10:15 Challenge in menopause: improving diagnosis and treatment F.M. Primiero

10:15-10:30 HR HPV genotypes on spermatozoa from male partners of infertile couplesA. Perino

10:30-10:45 BREAK

10:45-11:45 TRAINING IN COLPOSCOPYF. Boselli, P. Inghirami

10:45-11:00 Minimal standards in colposcopy M. Peroni

11:00-11:15 How to audit your colposcopy practice P. Cristoforoni

11:15-11:30 The nurse colposcopist: salvation or heresy? W. Prendiville

11:30-11:45 DISCUSSION

11:45-12:00 ECM TEST

ROOM B

ECM COURSE: HPV DISEASE OF THE LOWER GENITAL TRACT FOR PATHOLOGISTS. THIRD PART

08:30-10:00 ATEILER DE TRAVAILM.R. Giovagnoli, G.F. Zannoni

Interactive slide seminarL. Di Bonito, G. Negri

10:00-10:30 FOCUS ON GLANDULAR LESIONSL. Di Bonito, G. Negri

10:00-10:15 Atypical glandular cells and its differential diagnosis from true lesionsM. Desai

10:15-10:30 Histological implication of Pap-smear classified as atypical glandular cellG.F. Zannoni

10:30-10:45 BREAK

10:45-11:45 TRAINING IN CYTOPATHOLOGYL. Di Bonito, G.Negri

10:45-11:00 The role of cytotechnician in the labC. Bosco

11:00-11:15 How can I update myself: courses, books, e-learning, DIY (do it yourself)…?M.R. Giovagnoli

11:15-11:30 How to audit my own practice M. Desai

11:30-11:45 DISCUSSION

11:45-12:00 ECM TEST

ROOM APLENARY SESSION

12:00-12:45 AWARDS AND CONCLUSIONSA. Frega, C. Gentili

12:00-12:30 PRESENTATION AND AWARDING OF THE THREE BEST COMMUNICATIONS

12:30-12:45 AWARDING OF THE THREE BEST SPEAKERS

12:45-13:15 HPV DISEASE. CONCLUSIONS IN TWITTER STYLER. Senatori, S. Votano

12:45-12:51 HPV infection and cervical cancer L. Mariani

12:51-12:57 Screening around the world P. Davies

12:57-13:03 HPV vaccination R. De Vincenzo

13:03-13:09 Colposcopy today P. Walker

13:09-13:15 Cytology: quo vadis? G. Negri

13:15-13:30 CLOSING CEREMONY

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SpeakersB. Moscicki San Fransisco, U.S.

O. Nappi Naples, Italy

R. Nayar Evanston, U.S.

G. Negri Bolzano, Italy

P. Nieminen Helsinki, Finland

J. Paavonen Helsinki, Finland

A. Perino Palermo, Italy

M. Peroni Ascoli Piceno, Italy

G. Petricone Rome, Italy

K.U. Petry Wolsfburg, Germany

W. Prendiville Lyon, France

F.M. Primiero Rome, Italy

H. Sancho-Garnier Montpellier, France

R. Sankaranarayanan Lyon, France

M. Saville Victoria, Australia

P. Scirpa Rome, Italy

R. Senatori Rome, Italy

F. Sesti Rome, Italy

E. Siegler Haifa, Israel

P. Stentella Rome, Italy

G.L. Taddei Florence, Italy

S. Tatti Buenos Aires, Argentina

D. Valuta Chisinau, Moldova

N. Van der Veen Bilthoven, The Netherlands

A. Venuti Rome, Italy

S. Votano Rome, Italy

P. Walker London, UK

C. Zanardi Bologna, Italy

G.F. Zannoni Rome, Italy

SpeakersM. Barbero Asti, Italy

M. Benevolo Rome, Italy

C. Bergeron Paris, France

A. Biamonti Rome, Italy

C. Bosco Viareggio, Italy

F. Boselli Modena, Italy

C. Carriero Bari, Italy

M. Conyn-van Spaendonck Bilthoven, The Netherlands

P. Cristoforoni Genoa, Italy

T.M. Darragh San Francisco, U.S.

P. Davies Brussels, Belgium

R. De Vincenzo Rome, Italy

M. Desai Manchester, UK

S. Dexeus Barcelona, Spain

L. Di Bonito Trieste, Italy

J. Dillner Malmo, Sweden

L. Dillner Stockholm, Sweden

A. Frega Rome, Italy

D. French Rome, Italy

C. Gentili Carrara, Italy

P. Giorgi Rossi Rome, Italy

M.R. Giovagnoli Rome, Italy

M.T. Goodman Los Angeles, U.S.

P. Inghirami Rome, Italy

T. Khomasuridze Istanbul, Turkey

M. Kyrgiou London, UK

A. Lukic Rome, Italy

L. Mariani Rome, Italy

L. Micheletti Turin, Italy 2120

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General InformationLOCAL ORGANIZING COMMITTEEAlberto Biamonti, ItalyRosa De Vincenzo, ItalyDeborah French, ItalyGiancarlo Petricone, ItalyPaolo Scirpa, ItalyFrancesco Sesti, ItalySergio Votano, Italy

SCIENTIFIC COMMITTEEChristine Bergeron, FranceMina Desai, UKJoakim Dillner, SwedenAnkica Lukic, ItalyBarbara Moscicki, U.S.K. Ulrich Petry, GermanyWalter Prendiville, FrancePatrick Walker, UK

General InformationCONGRESS VENUEErgife Palace HotelVia Aurelia, 61900165 - Rome

LANGUAGEThe official language of the Workshop is English. Simultaneous translation intoItalian will be provided.

ECM ACCREDITATIONDuring the Congress there will be two ECM Courses, one in Room A and one inRoom B. The two courses will be simultaneous and will last three days (2 af-ternoon Sessions and 1 morning Session each). To obtain the credits is neces-sary to attend only one course, follow the 100% of the training activity and toexceed the questions proposed by the follow-up test. The effective attendeeswill be verified by signature of the dedicated records at the time of entranceand exit. Partial and missing survey of participation to the convention works,will not allow ECM accreditation. ECM Test will be distributed by hostesses.Participants will duly have to fill them in, sign and return them to the Secreta-riat.The Course “HPV DISEASE OF THE LOWER GENITAL TRACT FOR GYNAECOLO-GISTS” has been accredited for 5,5 ECM credits (712-114514).The Course “HPV DISEASE OF THE LOWER GENITAL TRACT FOR PATHOLO-GISTS” has been accredited for 5,5 ECM credits (712-114550).

The specialities and disciplines able to apply for Italian ECM credits are:- Medico Chirurgo/Surgeon (Anatomia Patologica; Igiene, epidemiologia e sanità pub-

blica; Ginecologia e Ostetricia; Oncologia; Patologia clinica (laboratorio di analisi chi-mico-cliniche e microbiologia));

- Biologo/Biologist (Anatomia Patologica; Igiene, epidemiologia e sanità pubblica; Pa-tologia clinica (Laboratorio di analisi chimico-cliniche e microbiologia));

- Tecnici di laboratorio biomedico/ Biomedical laboratory technicians.National educational aim n. 1: Applicazione nella pratica quotidiana dei principi e delleprocedure dell'evidence based practice/Application in the daily practice of the principlesand procedures of the evidence based practice.

PARTICIPANTS RECRUITMENTOn the 18th of January 2011 the National ECM commission defined: Sanitary professionals can usedirect sponsorships by agencies till 50 ECM credits out of the 150 ECM credits to be acquired throu-ghout three years 2014/16 with the registration of the order of belongings.The credit certificate will be checked out by COGEAPS and orders, associations where the profes-sional is registered till the greater quote of 1/3.

ORGANIZING SECRETARIAT

Triumph Italy S.r.l.Via Lucilio 60 - 00136 RomePhone: +39 06 35530 382Fax: +39 06 35530 [email protected]

Provider n. 712

Triumph ECM S.r.l.Via Lucilio, 60 – 00136 Rome

Ecm

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Floor plan

EXHIBITION AREA

ALPRETEC 7

ARROW DIAGNOSTICS 15

CENTREL 11

CLINIC SERVICE 9

DIGI MEDICA 4

FARMA-DERMA 12

FARMITALIA 17

FUJIREBIO 19

GALBERT 8

GENETICLAB 6

GYNIUS 10

HOLOGIC 18

IDI 3

LIBRERIA STUDIUM 1

LJ PHARMA 16

PROGINE 2

QIAGEN 20

REF 14

SAKURA 13

TEGEA 9

VERDUCI EDITORE 5

Floor plan

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SLIDE CENTREECNARTNE

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RECEPTION DESK

ROOM B

CLOACKROOM

1 2

3

4

5 6

7 8 9 10 11 12 20

14

15

18 19 ROOM A 16

13

17

Page 14: XII INTERNATIONAL WORKSHOP OF LOWER GENITAL TRACT … · LOWER GENITAL TRACT PATHOLOGY HPV diseases and cervical cancer: taking stock of the present and planning for the future. Rome

SponsorFor the unconditional educational support

Sponsor

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