PowerPoint Presentationgonorrhoea, trichomoniasis and syphilis including
maternal and congenital syphilis, 2016
Subtitle or presenter details March 2020
Photo credit: Kateryna Kon/Shutterstock
Human papillomavirus (HPV)
Most disease related to sexual transmission from:
* Included in this presentation
• Quantifying STI prevalence and incidence is important for planning interventions and advocating for resources
• WHO has produced global and regional prevalence and incidence estimates of four curable STIs in 15 to 49 year old men and women approximately every 5 years since 1995 (1995, 1999, 2005, 2008, 2012 and 2016)
WHO Estimates of Four Curable Sexually Transmitted Infections (STI) : Overview
Bacteria Chlamydia (Chlamydia trachomatis) Gonorrhoea (Neisseria gonorrhoeae) Syphilis (Treponema pallidum
subspecies pallidum)
WHO methods for estimating Chlamydia, Gonorrhoea and Trichomoniasis (2012 and 2016)
Step 1: Collecting and standardizing STI prevalence data
• Data collection: PubMed search by country, Outreach to WHO regional advisors, other experts
• Inclusion criteria: Representative of general population, no apparent bias in selection of study participants, used an internationally recognized diagnostic test, sample size of over 100, and for 2016 estimates - samples collected between 2009 and 2016
• Data standardized: Data adjusted to reflect performance characteristics of diagnostic test used, geography (urban/ rural) and age (chlamydia only)
Step 2: Generating regional estimates (10 regions)
• For all regions (except North America) prevalence estimates based on available data
• If 3 or more data points: Bayesian meta-analytic approach
• If less than 3 data points: ratios used (e.g., ratio of prevalence of chlamydia in men to women = 0.8)
• North American estimates based on CDC published estimates for US
• All regional prevalence estimates were increased by 10% to reflect higher risk populations
4
Regional estimates based on country maternal estimates generated using Spectrum STI and Spectrum STI prevalence database
• Spectrum STI: computer program developed to generate country estimates of prevalence levels and time trends. Users weight data based on how representative each data point is and the program. after standardizing the available data for diagnostic test type, generates trend estimates.
• Spectrum STI prevalence database: database synthesizes earlier multi- country databases and country data reported to the WHO, UNAIDS and UNICEF, through GAM
In addition: • Assumed ANC Prevalence = prevalence in women 15 to 49 =
prevalence in men 15-49 • Country prevalence estimates increased by 10% to reflect higher risk
populations
5
WHO Methods for Estimating STI Incidence
• For all regions, except North America, incidence estimated from prevalence using the approximation:
Incidence = Prevalence / Average duration of infection
• Regional values of average duration of infection for men and women based on literature and expert consultations. Values based on:
• Likelihood of being symptomatic or asymptomatic • Probability of getting treated if symptomatic or asymptomatic and
when • Average duration of infection if treated or not treated
• For North America published national US incidence estimates used
6
7
* does not include data from North America
The shading of the regional boxes reflects the number of studies; red means less than 3 studies and green more than 10
2016 curable STI estimates by World Health Organization
Region
WHO Incident case estimates of four curable STIs , 2016 (chlamydia, gonorrhoea, trichomoniasis, syphilis) 376 million new cases
WHO Region of the Americas
WHO Western Pacific Region
9
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
75 million
23 million
34 million
86 million
51 million
108 million
WHO STI Estimates: Incidence Rates in Women (ages 15 to 49) by WHO Region, 2016
95% Uncertainty Interval
Source: Rowley J, et al. WHO Bulletin, 2019
WHO STI Estimates: Incidence Rates in Men (ages 15 to 49) by WHO Region, 2016
95% Uncertainty Interval
Source: Rowley J, et al. WHO Bulletin, 2019
WHO STI Prevalence Estimates (%): 2016 vs 2012 Women 15 to 49 years of age
* Revised estimate for 2012 generated using Spectrum-STI when the 2016 estimate was produced
12
Source: Rowley J, et al. WHO Bulletin, 2019
WHO STI Prevalence Estimates (%): 2016 vs 2012 Men 15 to 49 years of age
* Revised estimate for 2012 generated using Spectrum-STI when the 2016 estimate was produced
13
WHO Region of the Americas
WHO Western Pacific Region
14
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Estimates of prevalence (%) * by WHO region Gonorrhoea, 2016
WHO Region of the Americas
WHO Western Pacific Region
15
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Estimates of prevalence (%)* by WHO region Trichomoniasis, 2016
WHO Region of the Americas
WHO Western Pacific Region
16
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Estimates of prevalence (%)* by WHO region Syphilis, 2016
WHO Region of the Americas
WHO Western Pacific Region
17
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Estimated prevalence (%)* by WHO region Chlamydia, 2016
African Region
18
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Prevalence (%)
African Region
19
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Prevalence (%)
African Region
Women
Men
20
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Prevalence (%)
African Region
21
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Prevalence (%)
Estimates of prevalent cases (‘000)* by WHO region Chlamydia, 2016
WHO Region of the Americas
WHO Western Pacific Region
22
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Estimates of prevalent cases (‘000)* by WHO region Gonorrhoea, 2016
WHO Region of the Americas
WHO Western Pacific Region
23
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Estimates of prevalent cases (‘000)* by WHO region Trichomoniasis, 2016
WHO Region of the Americas
WHO Western Pacific Region
24
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Estimates of prevalent cases (‘000)* by WHO region Syphilis, 2016
WHO Region of the Americas
WHO Western Pacific Region
25
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Estimated incidence rates (‘000)* by WHO region Chlamydia, 2016
WHO Region of the Americas
WHO Western Pacific Region
26
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Estimated incidence rates (‘000)* by WHO region Gonorrhoea, 2016
WHO Region of the Americas
WHO Western Pacific Region
27
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Estimated incidence rates (‘000)* by WHO region Syphilis, 2016
WHO Region of the Americas
WHO Western Pacific Region
28
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Estimated incident cases (‘000)* by WHO region, 2016 Chlamydia: 127 million new cases
WHO Region of the Americas
WHO Western Pacific Region
29
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Presenter
Presentation Notes
Alternate title - WHO global and regional estimates of the number of incident cases (‘000) in 2016 by disease and sex: Chlamydia
Estimated incident cases (‘000)* by WHO region, 2016 Gonorrhoea: 87 million new cases
WHO Region of the Americas
WHO Western Pacific Region
30
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Presenter
Presentation Notes
WHO global and regional estimates of the number of incident cases (‘000) in 2016 by disease and sex: Gonorrhoea
Estimated incident cases (‘000)* by WHO region, 2016 Trichomoniasis: 156 million new cases
WHO Region of the Americas
WHO Western Pacific Region
31
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Presenter
Presentation Notes
WHO global and regional estimates of the number of incident cases (‘000) in 2016 by disease and sex: Trichomoniasis
Estimated incident cases (‘000)* by WHO region, 2016 Syphilis: 6.3 million new cases
WHO Region of the Americas
WHO Western Pacific Region
32
femalemale
*Adults ages 15 to 49 years Source: Rowley J, et al. WHO Bulletin, 2019
Presenter
Presentation Notes
WHO global and regional estimates of the number of incident cases (‘000) in 2016 by disease and sex: Syphilis
Prevalence of 4 curable STIs by World Bank Income
Classification, 2016
34
WHO estimates of maternal and congenital syphilis,
2016
Congenital syphilis case rate by WHO region – 2012 and 2016
WHO Congenital Syphilis (CS) definition:
• all syphilis-related adverse birth outcomes (ABO) in infants born to treated and untreated women
AND
• infants born alive, without clinical signs, to untreated syphilis-infected women (called non-clinical CS)
36
Source: Korenromp EL, et al. PLOS ONE, 2019
Congenital Syphilis: Adverse Birth Outcomes by WHO region – 2012 and 2016
Source: Korenromp EL, et al. PLOS ONE, 2019
Missed opportunities
Maternal and congenital syphilis by WHO region – 2012 and 2016
Source: Korenromp EL, Rowley J, Newman L, Kamb M, Broutet N, Taylor MM et al.. PLOS ONE, 2019
38
Estimated ABO cases
African region
2012 35,055,000 1.62% 569,000 80% 35% 69% 247,000 222,000 469,000 1,377
2016 37,150,000 1.52% 564,000 83% 47% 76% 216,000 188,000 404,000 1,119 Region of the
Americas 2012 15,364,000 0.64% 98,000 97% 74% 84% 26,000 21,000 47,000 307 2016 15,253,000 0.86% 131,000 97% 82% 88% 30,000 21,000 51,000 339
Eastern Mediterranea
n Region
2012 17,866,000 0.69% 124,000 78% 44% 82% 55,000 49,000 104,000 597
2016 18,251,000 0.77% 140,000 78% 53% 85% 60,000 53,000 113,000 635 European
Region 2012 11,449,000 0.11% 13,000 97% 90% 90% 1,930 1,470 3,400 30 2016 11,289,000 0.10% 11,000 97% 94% 94% 1,260 940 2,200 19
South-East Asia Region
2012 37,889,000 0.32% 122,000 77% 59% 69% 46,000 39,000 85,000 231 2016 36,987,000 0.21% 78,000 87% 65% 71% 28,000 25,000 53,000 145
Western Pacific Region
2012 24,802,000 0.28% 70,000 94% 81% 67% 22,000 19,000 41,000 165 2016 24,297,000 0.26% 64,000 96% 84% 72% 20,000 18,000 38,000 156
World 2012 142,425,00
0 0.70% 996,000 85% 59% 74% 397,000 352,000 749,000 540
2016 143,227,00
0 0.69% 988,000 88% 66% 78% 355,000 306,000 661,000 473
Source: Korenromp EL, et al. PLOS ONE, 2019
Syphilis Estimates* 2016: Women ages 15 to 49 years
Korenromp EL, et al. Scientific Reports 2018.
<1.0%
1.0-3.5%
1.0-3.5%
1.0-3.5%
39
*Estimates using Spectrum STI, Avenir Health, N = 132 countries
Syphilis Trend Estimates* 2012 to 2016: Women ages 15 to 49 years
Korenromp EL, et al. Scientific Reports 2018.
Substantive decrease
Non-substantive decrease
Non-substantive increase
Substantive increase
No estimate
40
2016 curable STI estimates by Sustainable Development
Goal (SDG) Region
42
1,8 % 2,7 %
3,9 % 4,9 %
4,8 % 9,4 %
4,0 % 5,0 %
0,9 % 1,1 %
3,4 % 4,2 %
13,1 % 16,4 %
2,1 % 2,7 %
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
43
Source: Rowley J, et al. WHO Bulletin, 2019
Prevalence (%)* by SDG Region Gonorrhoea, 2016
44
0,2 % 0,3 %
0,7 % 0,8 %
1,1 % 1,2 %
1,7 % 1,9 %
0,3 % 0,4 %
0,9 % 1,0 %
8,1 % 9,3 %
0,3 % 0,4 %
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
Source: Rowley J, et al. WHO Bulletin, 2019
Prevalence (%)* by SDG Region Trichomoniasis, 2016
0,7 % 1,9 %
0,5 % 5,4 %
1,0 % 9,9 %
1,2 % 12,0 %
0,2 % 1,8 %
0,6 % 5,6 %
2,4 % 24,3 %
0,1 % 1,1 %
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
45
Source: Rowley J, et al. WHO Bulletin, 2019
Prevalence (%)* by SDG Region Syphilis, 2016
0,12 % 0,12 %
0,50 % 0,54 %
1,30 % 1,30 %
1,70 % 1,70 %
0,21 % 0,22 %
0,26 % 0,26 %
5,18 % 5,21 %
0,01 % 0,01 %
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
46
Source: Rowley J, et al. WHO Bulletin, 2019
Estimates of prevalent cases* ('000) by SDG Region Chlamydia, 2016
4 509 6 722
5 221 6 100
8 202 16 027
9 369 11 760
20 555
429 359
24 415
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
47
Source: Rowley J, et al. WHO Bulletin, 2019
Estimates of prevalent cases* ('000) by SDG Region Gonorrhoea, 2016
534 669
5 199
244 220
5 807
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
48
Estimates of prevalent cases* ('000) by SDG Region Trichomoniasis, 2016
4 719 1 827
3 418
66 635
32 558
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
49
Source: Rowley J, et al. WHO Bulletin, 2019
Estimates of prevalent cases* ('000) by SDG Region Syphilis, 2016
312 307
679 674
1 552
136 142
1 496
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
50
Source: Rowley J, et al. WHO Bulletin, 2019
Incidence rates (‘000) by SDG Region Chlamydia, 2016
28,8 28,1
47,6 43,8
60,0 84,1
39,6 42,1
37,4
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
51
Source: Rowley J, et al. WHO Bulletin, 2019
Incidence rates (‘000) by SDG Region Gonorrhoea, 2016
9,2 6,4
27,0 19,7
43,0 30,2
50,8 42,0
23,0
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
52
Source: Rowley J, et al. WHO Bulletin, 2019
Incidence rates* (‘000) by SDG Region Trichomoniasis, 2016
8,9 10,3
43,5 42,5
82,1 79,6
97,6 86,3
43,9
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
53
Source: Rowley J, et al. WHO Bulletin, 2019
Incidence rates (‘000) by SDG Region Syphilis, 2016
0,8 0,8
1,6 1,7
5,4 5,4
4,1 4,1
0,9
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
54
Source: Rowley J, et al. WHO Bulletin, 2019
Estimated incident cases ('000) by SDG Region Chlamydia, 2016
7 350 7 030
6 451 5 460
10 251 14 391
9 297 9 915
24 305
385 449
21 586
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
55
Source: Rowley J, et al. WHO Bulletin, 2019
Estimated incident cases* ('000) by SDG Region Gonorrhoea, 2016
2 341 1 615
3 667 2 454
7 334 5 162
11 930 9 901
18 187
590 880
13 291
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
56
Source: Rowley J, et al. WHO Bulletin, 2019
Estimated incident cases* ('000) by SDG Region Trichomoniasis, 2016
2 273 2 573
5 898 5 294
14 015 13 631
22 892 20 345
28 191
510 549
25 345
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
57
Source: Rowley J, et al. WHO Bulletin, 2019
Estimated incident cases ('000) by SDG Region Syphilis, 2016
196 193
217 214
915 918
964 969
491
• Estimates by SDG Region do not add up to totals as there are countries without SDG classification: Netherlands Antilles
femalemale
58
Source: Rowley J, et al. WHO Bulletin, 2019
2016 curable STI estimates in 10 estimation regions
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Prevalence* (%) in 10 estimation regions Chlamydia, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
1,9 % 3,0 %
1,4 % 2,0 %
10,4 % 13,0 %
3,3 % 4,2 %
4,0 % 5,0 %
4,8 % 9,4 %
3,5 % 4,3 %
2,1 % 2,7 %
0,6 % 0,7 %
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Prevalence* (%) in 10 estimation regions Gonorrhoea, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
0,2 % 0,2 %
0,2 % 0,3 %
3,8 % 4,4 %
1,5 % 1,7 %
0,7 % 0,8 %
1,1 % 1,2 %
0,9% 1,1 %
0,3 % 0,4 %
0,3% 0,3 %
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Prevalence* (%) in 10 estimation regions Trichomoniasis, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
1,3 %0,1 %
3,1 %1,9 %
9,8 %1,0 %
12,2 %1,2 %
5,0 %0,5 %
9,9 %1,0 %
6,0 %0,6 %
1,1 %0,1 %
1,5 %0,2 %
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Prevalence* (%) in 10 estimation regions Syphilis, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
0,12 % 0,12 %
0,14 % 0,14 %
0,83 % 0,84 %
1,88 % 1,88 %
0,29 % 0,31 %
1,30 % 1,30 %
0,26 % 0,27 %
0,06 % 0,06 %
0,20 % 0,21 %
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Prevalent cases* ('000) in 10 estimation regions Chlamydia, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
3 841 5 864
1 173 1 641
2 239 2 814
7 432 9 329
6 114 7 044
8 204 16 032
19 834 23 560
1 049 1 256
2 788 3 252
*Adults ages 15 to 49 years
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Prevalent cases* ('000) in 10 estimation regions Gonorrhoea, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
411 470
177 262
819 954
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Prevalent cases* ('000) in 10 estimation regions Trichomoniasis, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
249 2 458
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Prevalent cases* ('000) in 10 estimation regions Syphilis, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
242 239
114 111
178 181
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Incidence rates (‘000) in 10 estimation regions Chlamydia, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
26,1 28,0
34,0 27,9
103,4 109,7
33,2 35,2
50,3 45,1
60,0 84,1
40,7 38,3
30,6 25,7
5,8 6,2
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Incidence rates (‘000) in 10 estimation regions Gonorrhoea, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
9,1 6,2
9,2 6,9
116,1 95,9
44,2 36,6
26,9 18,9
43,0 30,2
31,2 24,2
16,3 10,8
8,5 7,0
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Incidence rates (‘000) in 10 estimation regions Trichomoniasis, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
10,5 10,7
5,7 9,3
79,4 70,3
99,5 88,0
41,2 40,1
82,1 79,6
49,3 46,5
9,3 10,0
12,5 11,1
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Incidence rates (‘000) in 10 estimation regions Syphilis, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
0,6 0,6
1,1 1,1
2,0 2,0
4,5 4,5
1,2 1,3
5,4 5,4
0,8 0,8
0,5 0,5
0,5 0,5
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Incident cases* ('000) in 10 estimation regions Chlamydia, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
5 136 5 445
2 854 2 293
2 222 2 373
7 375 7 865
7 641 6 325
10 254 14 396
23 190 20 736
1 501 1 209
2 769 2 745
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Incident cases* ('000) in 10 estimation regions Gonorrhoea, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
1 791 1 198
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Incident cases* ('000) in 10 estimation regions Trichomoniasis, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
2 067 2 077
Source: Rowley J, et al. WHO Bulletin, 2019
North Africa & Middle East
High income North America
Andean Latin America, Caribbean, Central Latin America, Southern Latin America, Tropical Latin America
Western Europe, Central Europe, Eastern Europe, Central Asia
Central Sub-Saharan Africa, Eastern Sub-Saharan Africa, Western Sub-Saharan Africa
Southern Sub-Saharan Africa
South Asia
Not applicable Data Source: World Health Organization Map Production: Health Statistics and Information Systems (HSI) World Health Organization
femalemale
Incident cases* ('000) in 10 estimation regions Syphilis, 2016
The boundaries and names shown and the designations used on this map do not imply the expressions of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or area of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement.
WHO 2015. All rights reserved.
126 124
89 87
43 44
Source: Rowley J, et al. WHO Bulletin, 2019
World Health Organization Global estimates of 4 curable STIs and maternal and congenital syphilis, 2016
76
Slide Number 2
WHO Estimates of Four Curable Sexually Transmitted Infections (STI) : Overview
WHO methods for estimating Chlamydia, Gonorrhoea and Trichomoniasis (2012 and 2016)
WHO methods for estimating Syphilis (2012 and 2016)
WHO Methods for Estimating STI Incidence
WHO STI Estimates: Data Availability for Chlamydia, Gonorrhoea & Trichomoniasis, 2016
Slide Number 8
WHO Incident case estimates of four curable STIs , 2016 (chlamydia, gonorrhoea, trichomoniasis, syphilis)376 million new cases
Slide Number 10
Slide Number 11
WHO STI Prevalence Estimates (%): 2016 vs 2012Women 15 to 49 years of age
WHO STI Prevalence Estimates (%):2016 vs 2012Men 15 to 49 years of age
Estimates of prevalence (%)*by WHO region Chlamydia, 2016
Estimates of prevalence (%) * by WHO regionGonorrhoea, 2016
Estimates of prevalence (%)*by WHO region Trichomoniasis, 2016
Estimates of prevalence (%)*by WHO region Syphilis, 2016
Estimated prevalence (%)* by WHO region Chlamydia, 2016
Estimated prevalence (%)*by WHO region Gonorrhoea, 2016
Estimated prevalence (%)* by WHO region Trichomoniasis, 2016
Estimated prevalence (%)*by WHO region Syphilis, 2016
Estimates of prevalent cases (‘000)*by WHO region Chlamydia, 2016
Estimates of prevalent cases (‘000)*by WHO region Gonorrhoea, 2016
Estimates of prevalent cases (‘000)*by WHO regionTrichomoniasis, 2016
Estimates of prevalent cases (‘000)*by WHO region Syphilis, 2016
Estimated incidence rates (‘000)*by WHO regionChlamydia, 2016
Estimated incidence rates (‘000)*by WHO region Gonorrhoea, 2016
Estimated incidence rates (‘000)*by WHO region Syphilis, 2016
Estimated incident cases (‘000)*by WHO region, 2016Chlamydia: 127 million new cases
Estimated incident cases (‘000)*by WHO region, 2016Gonorrhoea: 87 million new cases
Estimated incident cases (‘000)*by WHO region, 2016Trichomoniasis: 156 million new cases
Estimated incident cases (‘000)*by WHO region, 2016Syphilis: 6.3 million new cases
Slide Number 33
Slide Number 35
Congenital syphilis case rate by WHO region – 2012 and 2016
Congenital Syphilis: Adverse Birth Outcomesby WHO region – 2012 and 2016
Maternal and congenital syphilisby WHO region – 2012 and 2016
Syphilis Estimates* 2016:Women ages 15 to 49 years
Syphilis Trend Estimates* 2012 to 2016:Women ages 15 to 49 years
Slide Number 41
Prevalence (%)* by SDG Region Chlamydia, 2016
Prevalence (%)* by SDG Region Gonorrhoea, 2016
Prevalence (%)* by SDG Region Trichomoniasis, 2016
Prevalence (%)* by SDG Region Syphilis, 2016
Estimates of prevalent cases* ('000) by SDG Region Chlamydia, 2016
Estimates of prevalent cases* ('000) by SDG Region Gonorrhoea, 2016
Estimates of prevalent cases* ('000) by SDG Region Trichomoniasis, 2016
Estimates of prevalent cases* ('000) by SDG Region Syphilis, 2016
Incidence rates (‘000) by SDG Region Chlamydia, 2016
Incidence rates (‘000) by SDG Region Gonorrhoea, 2016
Incidence rates* (‘000) by SDG Region Trichomoniasis, 2016
Incidence rates (‘000) by SDG Region Syphilis, 2016
Estimated incident cases ('000) by SDG Region Chlamydia, 2016
Estimated incident cases* ('000) by SDG Region Gonorrhoea, 2016
Estimated incident cases* ('000) by SDG Region Trichomoniasis, 2016
Estimated incident cases ('000) by SDG Region Syphilis, 2016
Slide Number 59
Prevalent cases* ('000) in 10 estimation regionsChlamydia, 2016
Prevalent cases* ('000) in 10 estimation regionsGonorrhoea, 2016
Prevalent cases* ('000) in 10 estimation regionsTrichomoniasis, 2016
Prevalent cases* ('000) in 10 estimation regionsSyphilis, 2016
Incidence rates (‘000) in 10 estimation regionsChlamydia, 2016
Incidence rates (‘000) in 10 estimation regionsGonorrhoea, 2016
Incidence rates (‘000) in 10 estimation regionsTrichomoniasis, 2016
Incidence rates (‘000) in 10 estimation regionsSyphilis, 2016
Incident cases* ('000) in 10 estimation regionsChlamydia, 2016
Incident cases* ('000) in 10 estimation regionsGonorrhoea, 2016
Incident cases* ('000) in 10 estimation regionsTrichomoniasis, 2016
Incident cases* ('000) in 10 estimation regionsSyphilis, 2016