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Which factors predict outcome in the nonoperative treatment
of patellofemoral pain syndrome? A prospective
follow-up study
Kannus P, Nittymaki S. Med. Sci. Sports Exerc.
1994; 26(3): 289-296.
Was a defined, representative sample of patients assembled at a common point in the course of their disease?---Y
22 men, 27 women; 27± 9 y/o. 17- competitive athlete; 32- recreational
athlete All have a characteristic history and
symptom of the PFPS for one knee at least 2 months’ duration.
Was patient follow-up sufficiently long and complete?---Y
Training for 6 weeks, the correct performance of the exercise was controlled at weekly follow-up.
No follow-up of any kind was done between the 6-wks evaluation and that at 6 months( the final outcome assessment).
Were objective outcome criteria applied in a blind fashion?---Y
Visual Analog Scale( VAS )
Lysholm knee scores
Tegner functional knee scores
If subgroups with different prognosis are
identified, was there adjustment for
important prognostic factors?---N
All subjects served as a group and
received the same treatment.
Was there validation in an independent
group of patients?---N
49 patients visiting the clinic due to a
characteristic unilateral PFPS during a 3-
yr period were accepted in the analysis.
How likely are the outcomes over time?
Change scores compared to baseline measures (6-wks).
6-wk check point: age correlated to VAS (-0.41), Lysholm scores (-0.34), Tegner scores (-0.41).
6-months check point: age correlated to lysholm scores (-0.27), Tegner scores (-0.41).
How precise are the prognostic estimates?
Age accounted for less than 20% for the
variation seen in the outcome variables,
as determined by the r2-value of the age.
Confidence interval around the measure of prognosis
n= 49, p= 70%
SE= √ 0.7 * 0.3 / 49= 0.065= 6.5%
95% CI= 70% ± 1.96 * 6.5%
57.3% ~ 82.7%
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