Welcome to PDT & PD Update 2018pdt2018.com/.../uploads/2018/09/Conference-Booklet.pdf · 2018. 10. 8. · 2 Welcome to PDT & PD Update 2018 . following the tradition initiated in

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Welcome to PDT & PD Update 2018

following the tradition initiated in 1996 by Giulio Jori and Herwig Kostron, the 2nd post Brixen (Italy) Symposium PDT & PD Update 2018 will bring together students, researchers and clinicians working in all fields of photodynamic therapy (PDT) and photodiagnosis (PD) to foster the scientific developments in this field, thus contributing to their widespread use.

PDT & PD Update 2018 is designed to provide update lectures followed by related scientific presentations in each session, invited by the corresponding session chairs. Oral Poster-Pitches are intended to stimulate a walk through the poster sessions. Guided Poster-Walks should bring presenters and attendees close together thus motivating and encouraging discussions. While bringing young and experienced attendees together, sharing their opinions and experiences, we hope to contribute to establish new and strengthen already established networks of scientists, clinicians and pharmaceutical and medical device industry.

Located in Southern Bavaria, Kochel a. See offers impressive scenic views as well as interesting activities for relaxation after hard work during the conference days. At this point, we would like to thank the community of Kochel a. See and its major Mr. Thomas Holz for the opportunity to host this conference.

PDT & PD Update 2018 also thanks all sponsors and supporters to make this event possible.

Last but not least we thank YOU taking part in this interesting, interdisciplinary, intercultural translational field of science. YOUR active participation is the foundation for making PDT & PD Update 2018 a valuable and successful meeting.

JUMP IN with us

Ronald & Herbert & Adrian

Endorsed by:

Photodynamic Therapy & Photodiagnosis Update 2018

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Dear Participants and Guests of the International PDT-Symposium 2018

Prof Dr. Dr. h.c. Karl-Walter Jauch, Medical Director LMU-University Hospital Munich

It is a great pleasure to welcome all participants and guests from all over the world to the bi-annual PDT international meeting at this wonderful place near Munich. As head of the executive board of University Clinic of the Ludwig Maximilians University Munich I am very proud, that you have chosen Mr. Sroka and his team as organizers of your conference and Munich as the place to meet.

The combined use of drug and light for diagnostic and therapeutic medical use is an already old vision, starting with the Tirolean researcher Hermann von Tappeiner and Oscar Raab at the Institute of Pharmacology at the Ludwig Maximilians University in Munich more than a hundred years ago. In the nineties of last century the Urologist Alfons Hofstetter founded the Laser Institute at our Medical Campus Grosshadern and intensified research and development of further methods and applications in cooperation with physicists, multidisciplinary clinicians and researchers as well as international partners and industrial cooperations.

Nowadays its medical use in a large array of medical disciplines like gastroenterology, oncology, urology, neurosurgery, ENT, gynecology or dermatology and many others has become state of the art and is accepted by the FDA and EU.

Ongoing further developments will be presented and discussed during the next 3.5 days at the symposium with more than 200 participants. A special highlight will be the multidisciplinary interaction and discussion which is a prerequisite for successful translational research and translation of new technology into the clinic, which is our focus and special brand mark.

The organizers have chosen a wonderful place in the southern surroundings of Munich, where already some centuries ago Munich citizens, researchers and artists as well as monks went to spend their time for discussions and inspirations. I wish you all inspiring new insights and fruitful scientific discussions to get the initiation of new ideas and powerful motivation for your work. Furthermore of course the organizers asked for good weather and I hope you will have leisure time to also enjoy the local highlights of Bavarian Alps and lakes for personal interaction with old and new friendship.

Hope to see you again in Munich 2022

Yours

Karl-Walter Jauch

Medical Director LMU-University Hospital Munich

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Welcome address from the Dean of the Medical Faculty LMU Munich

Sehr geehrte Konferenz-Teilnehmer und Teilnehmerinnen,

zuerst darf ich ihnen Herr PD Dr. Sroka, Dr. Adrian Rühm, Dr. Herbert Stepp, sowie dem gesamten Organisationsteam danken, an einem sehr gut gewählten Ort eine so umfangreiche und international ausgerichtete Konferenz mit über 70 Vorträgen und ca. 100 Posterbeiträgen realisiert zu haben!

Als Zahnmediziner kenne ich das Anwendungsspektrum der PDT als antibakterielle photodynamische Therapie zur photo-aktivierten Desinfektion gut und verfolge mit großem Interesse die Anwendung beispielsweise in der Urologie, Dermatologie und Onkologie, sowie die international beachteten Forschungsleistungen an unserem LIFE-Zentrum, den Laser- und Immunologie-Forschungs-Einrichtungen am Klinikum der Universität München, welches an der Urologischen Klinik und Poliklinik, Leitung Prof. Dr. Christian Stief, verortet ist.

Hier wurde in einem interdisziplinären Forschungsfeld seit vielen Jahren sehr erfolgreich mit den Ausrichtungen Laser-Forschungslabor, Labor für Tumorimmunologie und Forschungslabore der Urologischen Klinik, eine Querschnittstechnologie entwickelt, vom Labormuster bis zum Prototypen.

Dies ist nur durch Zugang zu allem medizinischen Fachbereichen und gleichzeitiger Zusammenarbeit mit Chemie, Physik, Technologie, Industrie möglich und erlaubt biomedizinische Studien von in-vitro bis in-vivo. Etablierte Seniorwissenschaftler und medizinische Anwender in engem Kontakt mit Jungakademikern und Ärzten ermöglichen einen intensiven persönlichen Austausch. Eine außergewöhnlich gute Zusammenarbeit findet in München mit der Fakultät für Physik an der LMU (Frau Prof. Parodi) und der Fakultät für angewandte Naturwissenschaften und Mechatronik an der Hochschule München statt, sowie im DFG geförderten Graduiertenkolleg 2274 „Fortgeschrittene Medizinische Physik für bildgeführte Krebstherapie“.

Es freut mich besonders zu sehen, dass die photodynamische Therapie, welche durch einen LMU-Promovierenden, Oskar Raab, und dessen akademischen Lehrer, Pharmakologe Prof. Hermann von Tappeiner, entdeckt und an der Dermatologischen Klinik erstmals 1905 bei sechs Patienten zur klinischen Anwendung gebracht wurde, auch heute noch führend an unserer Medizinischen Fakultät weiterentwickelt wird.

Das Laser-Forschungslabor im LIFE-Zentrum ist ein physikalisch-technischer Motor an steter Weiterentwicklung und neuen Einsatzgebieten für Photo-Diagnostik und photodynamische Therapie und ein hervorragendes Beispiel für die Translation zwischen Physik-Technik und Medizin. Es erhält weltweite Anerkennung und Beachtung, insbesondere durch die einzigartig enge Verzahnung, Anbindung und unmittelbare Nähe zur Klink.

PDT&PD ist ein spannendes Feld für die Zukunft, im Hinblick auf innovative Anwendungen im Health-Bereich. Ich wünsche der Konferenz und den weit über 200 Teilnehmern aus der ganzen Welt einen guten Verlauf, interessante Diskussionen und fruchtbaren Austausch.

Mit freundlichen Grüßen

Prof. Dr. Reinhard Hickel Dekan Medizinische Fakultät der LMU-München


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Committees

Organising Committee:

Wolfgang Bäumler Céline Frochot Herwig Kostron Lothar Lilge Tim Maisch Serge Mordon Kristjan Plätzer Angelika Rück Adrian Rühm Ronald Sroka Herbert Stepp

Scientific Program Committee:

Kristian Berg Christian Betz Arjen Bogaards Julia Buchholz Céline Frochot Tayyaba Hasan Peter Hillemanns Colin Hopper Mladen Korbelik Serge Mordon Santi Nonell Carsten Philipp Angelika Rück Adrian Rühm Mathias Senge Ronald Sroka Herbert Stepp Georges Wagnières Xiuli Wang Georg Widhalm

Local Organising Committee: Maximilian Aumiller, Kornelia Eberle, Maximilian Eisel, Christian Freymüller, Christian Heckl, Christian Homann, Alexander Lang, Thomas Pongratz, Adrian Rühm, Lei Shi, Ronald Sroka, Herbert Stepp, Stephan Ströbl

Laser-Research-Laboratory (LFL) /LIFE Center, Department of Urology, Hospital of the Ludwig-Maximilians-University, Munich

Gerhard von Bültzingsloewen, Congress Organiser (PCO) LMU Congressconsulting

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General Information Conference Staff Identification

Bavarian blue-white scarf

Conference Hotline

Service contact for resolving urgent problems / questions (phone call, message, WhatsApp): Gerhard v. Bültzingsloewen +49 151 555 243 58

or e-mail contact:

[email protected]

Conference Venue and Site Maps

Please refer to pages 9 - 11

Registration

Badge pick-up is at the registration desk in the entrance hall of the Heimatbühne. Please have your ticket with the QR-Code ready to achieve a fast registration process. On-site registration and payment (cash or credit card) is possible for a limited number of attendees.

Registration times Tuesday 18.09. 11:00 - 20:00

Wednesday 19.09. 07:45 - 17:30

Thursday 20.09. 07:45 - 17:30

Friday 21.09. 07:45 - 18:50

Saturday 22.09. 07:45 - 13:00

The registration fee includes welcome reception, admission to conference sessions, company and poster pitches and coffee breaks. Together with your badge you will receive your certificate of attendance and (if needed) an additional printed receipt. If you have booked for the PDT-school, there will be a separate certificate. For information concerning your personal registration or changing your registration options, please refer to a staff member at the registration desk.

The QR-code on your badge also encodes your choices of lunch and social events .Please wear it or have it at hand at all times!

Protection of data privacy

Please assist in protecting data privacy. It is not allowed to take pictures or videos of presentations or posters. Please ask presenters for permission before taking pictures or videos.

Information for Contributors Speaker Check-In and Preview Station

Speaker check-in for presentation upload and preview is in the entrance hall near the registration desk. Speaker check-in is available during on-site registration times and closes 15 min before session start, to allow session preparation.

Please keep strictly to your presentation time as indicated in the program. In order to stay on schedule, session chairs will abort the presentation after the allocated time. You will see a countdown clock during your presentation.

Conference laptops provide Microsoft Windows 10 and Office 2016 and Adobe pdf reader. We strongly advise presenters to bring their presentations on USB drive in PowerPoint or pdf format and upload them at the speaker check-in. The projector provides 16:9 and 4:3 format.

Poster and Industry Exhibition

The poster and industry exhibition can be found near the side entrance on the left (see map p.9).

Poster sessions

Posters shall be presented in two groups in two different time periods, depending on the poster-number. See below to find out about your poster group, hang-up and removal times. Your poster-number can be found in the Poster-Overview section in this booklet. Fixation material is available at the registration desk and in the poster halls. Please DO NOT use needles. Hang-up your poster on the board designated with your poster number. Please be present at your poster during poster-walk and be prepared for explanation and questions.

mailto:[email protected]


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Poster Group 1: Poster-numbers 101 - 513 Hang-up Wed. 19th 07:45 - 08:30

Poster-walk Thu. 20th 13:30 - 14:00

Removal Thu. 20th 15:00 - 17:30

Poster Group 2: Poster-numbers 514 - 1307 Hang-up Fri. 21st 07:45 - 08:30

Poster walk Fri. 21st 13:30 - 14:00

Removal Sat. 22nd after lunch

Poster Awards

There will be some awards for best posters and best poster pitches. The lucky winners will be announced during the Gala Dinner. Award Sponsors are:

On-site Services WiFi Access

Free WiFi will be available, yet with limited capacity. Connection speed will depend on the number of simultaneous users. Please use the WiFi only for messaging, but not for excessive data streaming.

We do not take any responsibility for computer damages, viruses, malware etc. that may potentially be inferred by establishing network connections.

Storage of Luggage and Clothing

All attendees are self-responsible for their luggage and clothing. We do not take over any liability for lost or damaged luggage and clothing.

Cost-free parking

Cost-free parking lots are located next to the conference venue.

Train Station Kochel a. See

The Train Station Kochel a. See is located next to the main street (B11/Mittenwalder Straße). When coming from the Heimatbühne, you have to follow the main street in direction Benediktbeuern, walking distance is 950 m or 15 min. (see Map p. 10)

Guest Card

When checking in at your hotel in the Kochel/Benediktbeuern/Walchensee region, you will obtain a tourist / guest card which allows for free rides in local buses and reduced entry fees to tourist attractions. If you don’t receive a guest card during check ask for it in your hotel.

Tourist information

The tourist information can be found next to the Train Station Kochel a. See (see map p. 10). A tourist agent will be available at Heimatbühne at specific times and there will be an information desk next to the registration with information material about Kochel a. See and the region. A specific program for accompanying persons will be offered at the registration desk.

Food and Beverage Services Lunch

If you have selected one or more of the conference lunch options, you will find colored lunch vouchers in your personal conference envelope. You have to hand over your voucher in order to receive your selected lunch choice.

Served lunch will be available in the adjoining restaurant, “Kochler Stuben” (see map p. 9).

Take away lunch-boxes are served on the rear side of the poster-exhibition hall” (see map p. 9).

Lunch tickets are still available at the registration. You can also find restaurants in Kochel a. See in walking distance.

Breaks

Complimentary coffee, tea, water, snacks, and fruits will be served once (Tuesday and Saturday) or twice (Wednesday till Friday) per day in the conference hall.

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Social Events

Participation in Social Events

Participation in social events depends on your individual selection during conference registration. On-site registration for social events (except Boat Trip) is still possible at the registration. More details can be found here: http://pdt2018.com/social-program/

Participation in social events is at your own risk. Depending on the weather forecast, please arrange for warm and weatherproof outfit and umbrella. For safety reasons, the Mountain Hut event at Herzogstand or the Boat Trip may be cancelled in case of bad weather. In this case your corresponding payment will be refunded to you.

Welcome Reception

The welcome reception will take place on Tuesday at 18:30 in Heimatbühne. Drinks and finger food buffet will be available. As special event a traditional Bavarian dance show will take place during the evening.

Mountain Hut

The mountain hut dinner at the Herzogstand summit will take place on Wednesday evening:

Meet at 17:30 latest in front of the Heimatbühne for bus transfer to the cable car station. The bus transfer takes about 15 min, the cable car ride takes 4 min to take you from 809 to 1600 m altitude.

Please mind that sunset will be at 19:20. If you decide to take a walk to one of the nearby summits – please ask/inform one staff member about your hike. Please be back at the Herzogstand hut latest at 19:30 for dinner. From the top station of the cable car, there is a scenic 10 min walk to the hut. The broad path itself is not steep, but the mountain slope surrounding is steep at some places. Please walk carefully and watch your step - especially on the way back to the cable car when it will be dark. Torches are available together with additional lighting by staff members.

Departure at Herzogstand starts at 22:00. Walk from the mountain hut to the cable car mountain station in groups of 15 people. From the valley station, bus transfer to Kochel and Benedikbeuern will be available.

Boat Trip Thursday at 17:30: Meeting point in front of the conference venue (Heimatbühne). - Look for the “Boat Trip” sign. - Walk together to the landing stage (~400m). Drinks and Snacks are available at your own expense.

Franz Marc Art Museum Thursday at 17:30: Meeting point in front of the conference venue (Heimatbühne). - Look for the “Franz Marc” sign. - Walk together to the museum (~900m).

Open-Air-Historical-Garden Glentleiten Thursday at 17:30: Meeting point in front of the conference venue (Heimatbühne). - Look for the “Glentleiten” sign. - Bus transfer (~10 min) will be available.

Gala dinner Friday: Gala dinner at Benediktbeuern monastery

Meet at train station Kochel a. See at 19:35 latest for a 6 min train transfer to the monastery (no bus transfer available). Train will depart at 19:45, dinner starts at 20:00. Train tickets will be provided.

Return to Kochel a.See: By bus at 23:00 and 24:00. By train at 23:30. Capacity 50 people for each journey. If you want to leave earlier there are trains at 21:30 and 22:30 – if you want to stay longer there is one later train at 00:30. Transport between 23:00 and 24:00 is included – if you choose other travel times please get your train ticket at the station. Attendees from more than 20 nations will have dinner together. To make this a colorful event, please feel encouraged to bring and wear your local costumes.

http://pdt2018.com/social-program/


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Room Overview of the conference venue (Heimatbühne)

Address of Heimatbühne:

Mittenwalder Straße 14 82431 Kochel a. See, Germany

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Map of Kochel a. See


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Map of the surroundings of Kochel a. See


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Program Overview

Tuesday 18.09.

12:00 - 16:00 PDT - School 18:30 – 21:00 Welcome Reception

Wednesday 19.09.

08:30 Opening 09:00 Photosensitizers 10:45 Targeted PDT 11:30 Combinations in PD-PDT

13:00 - 14:00 Lunch / Lunch Boxes 14:00 Company Pitches 14:30 Combinations in PD-PDT 16:15 PDT-world 1

17:30 – 23:00 Herzogstand Mountain Hut

Thursday 20.09.

08:30 Antimicrobial 10:30 Physics 11:45 Poster Pitches 1

12:35 – 13:30 Lunch / Lunch Boxes 13:30 Poster Walk 1 14:30 Mechanisms 16:15 PDT-world 2

17:30 – 19:30 Glentleiten, Franz Marc Museum, Boat Trip

Friday 21.09.

08:30 Immuno-PDT 10:30 Clinical Use 1 12:00 Poster Pitches 2

12:50 – 13:30 Lunch / Lunch Boxes 13:30 Poster Walk 2 14:30 Clinical Use 2 16:30 Clinical Use 3

20:00 – 24:00 Gala Dinner

Saturday 22.09

08:30 Clinical Use 4 10:15 Future and Hot Topics 11:45 Closing remarks 12:00 O’ zapft is

12:10 – 13:00 Lunch / Lunch Boxes

The program may be subject to changes at short notice. These will be announced in course of the conference.


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Conference Program

PDT - School 12:00 – 13:00 Photophysics and photochemistry

PDTS-01 Santi Nonell 13:00 – 14:00 Cell death mechanisms and immune response

PDTS-02 Sandra Gollnick

14:00 – 14:20 Break

14:20 – 15:00 Antimicrobial PDTS-03 Tim Maisch

15:00 – 15:20 Photodetection PDTS-04 Herbert Stepp

15:20 – 16:00 Light dosimetry PDTS-05 Gal Shafirstein

Welcome Reception 18:30 – 21:00 Finger food, drinks, traditional Bavarian dance show

Tuesday 18th September

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Opening 8:30 – 9:00 Introduction remarks Ronald Sroka

Session 1 Photosensitizers Mathias Senge, Tayyaba Hasan

9:00 – 9:30 Update on Photosensitizers and targeted PDT: is it all in the packaging and the use of nanotechnology, or are new small molecules still needed? OS-01-01 Tayyaba Hasan

Wellman Center for Photomedicine, Harvard University and MIT, USA 9:30 – 9:45 Development of new photosensitizers for the photodynamic inactivation of bacteria OS-01-02 Arno Wiehe, C. S. Gutsche, B. F. Hohlfeld, S. Gräfe, B. Gitter, K. J. Flanagan,

M. Senge, N. Kulak Freie Universität Berlin, DEU/biolitec research GmbH, DEU

9:45 – 10:00 Nanos from phthalos: Designing, improving and looking forward OS-01-03 Fabienne Dumoulin

Gebze Technical University, TUR 10:00 – 10:15 Solubilization of Challenging Small Molecule Drugs by Peptide-Polymer Conjugates

OS-01-04 Dario Remmler, H. G. Börner Humboldt-Universität zu Berlin, DEU

10:15 – 10:45 Break

Session 2 Targeted PDT Céline Frochot

10:45 – 11:00 Polyamines as targeting agents for photosensitizers in photodynamic therapy of cancers

OS-02-01 Vincet Sol University of Limoges, Laboratory PEIRENE EA 7500, Limoges, FRA

11:00 – 11:15 Targeted Photodynamic Therapy with Metal-based Photosensitizers OS-02-03 Gilles Gasser

Chimie ParisTech, PSL University, FRA 11:15 – 11:30 Peptide targeting of photosensitisers for PDT and drug delivery

OS-02-04 Ian Eggleston University of Bath, Bath, GBR

Session 3.1 Combinations in PD or PDT 1 Angelika Rück 11:30 – 12:00 X-ray – PDT - PD combinations

OS-03-01 Brian Pogue Dartmouth College, Thayer School of Engineering, USA

12:00 – 12:15 Singlet oxygen detection in PDT OS-03-02 Santi Nonell, R. Bresolí-Obach

Universitat Ramon Llull, ESP 12:15 – 12:30 Phosphorescent photosensitizers to follow up PDT response by FLIM and PLIM

OS-03-03 Angelika Rück, J. Breymayer, K. Reess ,S. Kalinina University of Ulm, DEU

12:30 – 12:45 The application of optical coherence tomography angiography in vascular targeted photodynamic therapy

OS-03-04 Haixia Qiu, Y. Gu Chinese PLA General Hospital, CHN

12:45 – 13:00 Enhancing the efficacy of gene-directed enzyme prodrug therapy by photochemical internalization

OS-03-05 Henry Hirschberg, K. Berg University of California, USA

Wednesday 19th September


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Company Pitches Ronald Sroka, Herbert Stepp 14:00 – 14:30 Max. 2-3 minutes each

Session 3.2 Combinations in PD or PDT 2 Brian Pogue

14:30 – 15:00 Light-controlled delivery of cancer immunotherapeutics OS-03-06 Pal Selbo

Oslo University Hospital, NOR 15:00 – 15:15 Mechanisms of hypericin-induced immunity: chronology of investigations

OS-03-07 Barbara Krammer, T. Verwanger, R. Sanovic, D. Rauch, P. Cantonati, J. Stump, E. Obregón-Castrillo, N. Maeding

University of Salzburg, AUT

15:15 – 15:30 Tumor Oxygenation and Blood Flow: Tracking and Tweaking for More Efficacious PDT OS-03-08 Theresa Busch , A. G. Yodh, Y.H. Ong

University of Pennsylvania, USA 15:30 – 15:45 Bladder wall light dose distribution during Photodynamic Therapy

OS-03-09 Lothar Lilge, G. Kulkani, A. Manalac, J. Cassidy, W. Embree, A. Mandel, V. Betz, M. Jewett University of Toronto, CAN

15:45 – 16:15 Break

Session 4.1 PDT World 1 Ying Gu

16:15 – 16:30 Application and development of PDT in China OS-04-01 Xiuli Wang

Shanghai Skin Disease Hospital, Tongji University School of Medicine, CHN 16:30 – 16:45 The status of the Brazilian program of PDT for basal cell carcinoma

OS-04-02 Cristina Kurachi, A.G. Salvio, V.S. Bagnato University of São Paulo, BRA

16:45 – 17:00 Clinical application and perspectives of PDT in Russia OS-04-03 Andrey Akopov & Elena Filonenko

Pavlov First State Medical University,RUS / P.A.Herzen Cancer Research Institute, RUS

Conclusions Finding Ronald Sroka, Herbert Stepp 17:00 – 17:20 Session Chairs of the day

Mountain Hut Herzogstand 17:30 Bus transfer to cable car, meet in front of the conference venue (Heimatbühne)

19:30 – 22:00 Dinner ≈22:00 Begin of return to cable car mountain station in groups of 15 persons ≈23:00 Return by busses to Kochel / Benediktbeuern

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Session 5 Antimicrobial Santi Nonell

8:30 – 9:00 Antimicrobial PDT - UPDATE OS-05-01 Tim Maisch

University Hospital Regensburg, DEU 9:00 – 9:15 Protein carriers for delivery of photosensitizers in antibacterial treatment

OS-05-02 Cristiano Viappiani, S. Abbruzzetti, C. Montali, S. Nonell Università di Parma, ITA

9:15 – 9:30 Application of Photodynamic Inactivation based on natural photosensitizers against plant pathogens OS-05-03 Kristjan Plaetzer, M. Glueck, C. Hamminger, M. Fefer, J. Liu, R. Tenhaken

University of Salzburg, AUT 9:30 – 9:45 Using natural deep eutectic solvents (NADES) as photosensitiser solubiliser

OS-05-04 Ellen Bruzell, , K. Wikene, H. Valen, H.H. Tønnesen Nordic Institute of Dental Materials (NIOM), NOR

9:45 – 10:00 Photochemical internalization enhances cytosolic release and efficacy of antibiotics against staphylococcal infection OS-05-05 Pal Selbo, X. Zhang, L. de Boer, L. Heiliegers, S. Man-Bovenkerk, J. W. Drijfhout, A. Høgset, S. A. Zaat

Oslo University Hospital, NOR

10:00 – 10:30 Break

Session 6 Physics Georges Wagnières 10:30 – 11:00 Treatment Planning and Dosimetry in Interstitial PDT – An Update

OS-06-01 Gal Shafirstein, E. Oakley, D. Bellnier Roswell Park Comprehensive Cancer Center, USA

11:00 – 11:15 Reducing dosimetry needs in PDT OS-06-02 Brian Pogue

Dartmouth College, Thayer School of Engineering, USA 11:15 – 11:30 Dosimetry issues for intraoperative PDT of glioblastoma

OS-06-03 Clément Dupont, M. Vermandel, S. Mordon Université. Lille, FRA

11:30 – 11:45 Spectral online monitoring during interstitial PDT OS-06-04 Adrian Rühm, C. Heckl, M. Aumiller, H. Stepp, R. Sroka

Klinikum der Universität München, DEU

Poster Pitches 1 Ronald Sroka, Herbert Stepp 11:45 – 12:35 2 min each

Session 1: Photosensitizers 101 Weimin Liu / 102 Julien Massiot

Session 2: Targeted PDT 201 Ludovic Bretin / 202 Xiaosong Li / 203 Marline N'Diaye / 204 Nelson A.M. Pereira/205 Abdul-Amir Yassine / 206 Zahraa Youssef

Session 3: Combinations in PD or PDT 301 Pilar Acedo / 302 Jens Buentzel / 303 Cristina Kurachi / 304 Jayoti Som / 305 Andrea Tabero / 306 Steven Yap

Session 5: Antimicrobial 501 Antonella Battisti / 502 Anzhela Galstyan / 503 Paola Morici / 504 Antonella Sgarbossa


Thursday 20th September


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Poster Walk 1 Session chairs of the day 13:30 – 14:00

S1 Photosensitizers Mathias Senge, Tayyaba Hasan S2 Targeted PDT Céline Frochot S3 Combinations in PD or PDT Angelika Rück, Brian Pogue S4.1 PDT World 1 Ying Gu S5a Antimicrobial Santi Nonell

14:00 – 14:30 Break

Session 7 New Mechanisms Kristian Berg

14:30 – 15:00 Subcellular mesoscale directing of photosensitizers: An update on the mechanistic augmentation of cellular phototoxicity OS-07-01 Girgis Obaid, I. Rizvi, T. Hasan, D. Kessel

Massachuestts General Hospital and Harvard Medical School, USA

15:00 – 15:15 Molecular targeted PDT: induction of antibiotic susceptibility of multi-drug resistant Staphylococci OS-07-02 Zvi Malik, N. Iluz

Bar-Ilan University, ISR 15:15 – 15:30 Molecular pathways involved in the acquired PDT resistance

OS-07-03 Valentina Rapozzi, F. D’Este, E. Della Pietra, L.E Xodo University of Udine, ITA

15:30 – 15:45 Photochemical Internalization of sunitinib; mechanistic challenges OS-07-04 Anette Weyergang, J. Wong

Oslo University Hospital, Oslo, NOR

15:45 – 16:15 Break

Session 4.2 PDT World 2 Serge Mordon 16:15 – 16:30 PDT in North America: Has Love’s Labor’s Lost the profit in their shining nights?

OS-04-04 Keith Cengel University of Pennsylvania, Philadelphia, PA, USA

16:30 – 16:45 PDT in Europe OS-04-05 Céline Frochot, S. Mordon

CNRS-University of Lorraine, FRA

16:45 – 17:00 Semiconductor metal oxides based nanoparticles as a new class of photosensitisers for effective PDT OS-04-06 Xia Lou

Curtin University,, AUS


Social Events 17:30 Open-Air Historical Garden Glentleiten

Bus transfer, meet in front of the conference venue (Heimatbühne) 17:30 Franz Marc Museum

Walk to Franz Marc museum, meet in front of the conference venue (Heimatbühne) 17:30 Boat Trip

Walk to boat jetty, meet in front of the conference venue (Heimatbühne)

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Session 8 Immuno-PDT Arjen Bogaards, Mladen Korbelik 8:30 – 9:00 Anti-tumor immunity induced with in situ or ex vivo PDT

OS-08-01 Mladen Korbelik Integrative Oncology Department, BC Cancer, CAN

9:00 – 9:15 Immunomodulation in the Setting of Intraoperative Photodynamic Therapy OS-08-02 Theresa Busch, K.A. Cengel, R.W. Davis IV

University of Pennsylvania, USA 9:15 – 9:30 T cell-based Immuno-Photodynamic therapy of cancer

OS-08-03 Ferry Ossendorp Leiden University Medical Center, NDL

9:30 – 9:45 Augmenting the effects of VTP therapy in urologic cancers OS-08-04 Kwanghee Kim, M. O’Shaughnessy, J. Coleman

Memorial Sloan Kettering Cancer Center, USA

9:45 – 10:00 Mechanisms of PDT-Enhanced Anti-tumor Immunity and Implications for Checkpoint Blockade OS-08-05 Sandra Gollnick, R. Falk-Mahapatra, K. Ramsey

Roswell Park Comprehensive Cancer Center, USA

10:00 – 10:30 Break

Session 9 Clinical Use 1 (derma, gastro, lung, ENT)

Colin Hopper

10:30 – 10:50 PDD and PDT in head and neck cancers OS-09-01 Colin Hopper, C. Betz

Maxillofacial Surgeon UCL Eastman London, GBR 10:50 – 11:05 Next generation Targeted Photodynamic Therapy (NG-PDT)

OS-09-02 Harubumi Kato, T. Hamakubo Tokyo Medical University, JPN

11:05 – 11:20 Update of PDT in Dermatology OS-09-03 Carola Berking, R. Koseki, and T. Tanaka

Klinikum der Universität München, DEU

11:20 – 11:35 Current clinical studies with ALA-PDD application in the fields "lung, gastro, pancreas and bladder" in Japan OS-09-04 Mitsugu Yamauchi

SBI Pharmaceuticals Co., Ltd, JPN 11:35 – 11:50 Lessons learned in dermatological PDT – What Really Mattered

OS-09-05 Alexis Sidoroff Department of Dermatology and Venerology, AUT

11:50 – 12:00 Q & A OS-09-06 Colin Hopper

Maxillofacial Surgeon UCL Eastman London, GBR

Friday 21st September


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Poster Pitches 2 Ronald Sroka, Herbert Stepp 12:00 – 12:50 2 min each

Session 6: Physics 601 Mirian Stringasci

Session 7: New mechanisms 701 Sylvestre Bonnet / 702 Hilde Harb Buzza / 703 Vipin Shankar Chelakkot / 704 Leonardo Franchi

Session 8: Immuno-PDT 801 Aleksandra Kawczyk-Krupka / 802 Rainer Wittig

Session 9-12: Clinical use 901 Thomas Giesen / 902 Jie JI / 903 Wojciech Latos / 904 Maxim Loshchenov / 905 Lei Shi / 906 Artem Shiryaev / 907 Linglin Zhang / 1001 Aleksandra Kawczyk-Krupka

Session 13: Future and Hot Topics 1301 Jaroslava Joniova / 1302 Eduard Mahiliavets / 1303 Georges Wagnières


Poster Walk 2 Session chairs 13:30 – 14:00

S5b Antimicrobial Santi Nonell S4.2 PDT world 2 Serge Mordon S6 Physics Georges Wagnières S7 New mechanisms Kristian Berg S8 Immuno-PDT Arjen Bogaards, Mladen Korbelik

S9-12 Clinical use C. Hopper, P. Hillemanns G. Widhalm, H. Kostron, J. Buchholz S13 Future and Hot Topics Ronald Sroka, Herbert Stepp

14:00 – 14:30 Break

Session 10 Clinical use 2 (gyn , uro) Peter Hillemanns 14:30 – 15:00 TOOKAD®Soluble (Padeliporfin) VTP; EMA approval and 4 years follow up

OS-10-01 Avigdor Scherz Weizmann Institute of Science, ISR

15:00 – 15:15 Intraperitoneal photodynamic therapy for ovarian cancer: a way to stimulate antitumor immunity?

OS-10-02 Henri Azaïs, M. Baydoun, C. Frochot, L. Colombeau, A. Grabarz, O. Moralès, P. Collinet, N. Delhem, S. Mordon

Hôpital La Pitié Salpêtrière, FRA 15:15 – 15:30 Topical Photodynamic Treatment for HPV Infections and Cervical Dysplasia

OS-10-03 Peter Hillemanns Medizinische Hochschule Hannover, DEU

15:30 – 15:45 Sentinel detection using near infrared fluorescence from ICG in vulvar and cervical cancer

OS-10-04 Philipp Soergel Medizinische Hochschule Hannover, DEU

15:45 – 16:00 5-Aminolevulinic acid photodynamic therapy in cervical intraepithelial neoplasia concurrent vaginal intraepithelial neoplasia: Series of ten cases

OS-10-05 Yi Yang Peking Union Medical College Hospital, CHN

16:00 – 16:30 Break

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Session 11 Clinical use 3 (neuro) Georg Widhalm, Herwig Kostron OS-11-01 PD and PDT in Neurosurgery – UPDATE shifted to >>SATURDAY morning (10:15)

Walter Stummer Universitätsklinikum Münster, DEU

16:30 – 16:45 Current and novel applications of photodynamic diagnosis with 5-ALA to optimize neurosurgical procedures OS-11-02 Georg Widhalm

Medical University Vienna, AUT 16:45 – 17:00 The Road to 5-ALA FDA Approval in the US

OS-11-03 Constantinos Hadjipanayis Dept. of Neurosurgery, Mount Sinai, USA

17:00 – 17:15 Limiting glioma development by photodynamic therapy-generated macrophage vaccine and allo-stimulation: an in vivo histological study in rats OS-11-04 Henry Hirschberg, S. J. Madsen, Q. Peng

University of California, USA 17:15 – 17:30 Interstitial Photodynamic Therapy as initial treatment of de-novo Glioblastomas

OS-11-05 Friedrich-Wilhelm Kreth Klinikum der Universität München, DEU

17:30 – 17:45 INDYGO – intraoperative PDT for newly diagnosed GBM, preliminary results OS-11-06 Maximilien Vermandel, C. Dupont, F. Lecomte, P. Deleporte, S. Mordon, N. Reyns

Université Lille, FRA 17:45 – 18:00 In silico evaluation of interstitial photodynamic therapy

OS-11-07 Takahiro Nishimura, A. Izumoto, H. Hazama, N. Ikeda, Y. Kajimoto, T. Kuroiwa, K. Awazu

Osaka University, JPN 18:00 – 18:15 5-ALA fluorescence for guidance in stereotactic brain tumor biopsy

OS-11-08 Neda Haj-Hosseini, J. Richter, P. Milos, M. Hallbeck, K. Wårdell Linköping University, SWE

18:15 – 18:30 5-ALA is a promising marker for detection of tumor invasion in the surrounding brain tissue of brain metastases OS-11-09 Petra A. Mercea, A. S. Berghoff, A. Wöhrer, M. Millesi, B. Kiesel, M. Mischkulnig,

M. Preusser, J. A. Hainfellner, E. Knosp, G. Widhalm Medical University of Vienna, AUT


18:50 – 19:35 Break

Gala dinner 19:35 Meet at train station Kochel a. See (no bus transfer) 19:45 Train departure 20:00 Dinner

23:00 - 0:00 Return by bus at 23:00 and 24:00 and by train at 23:30. Capacity 50 people for each journey. If you want to leave earlier there are trains at 21:30 and 22:30 – if you want to stay longer there is one later train at 00:30. Transport between 23:00 and 24:00 is included – if you choose other travel times please get your train ticket at the station.


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Session 12 Clinical use 4 (veterinary) Julia Buchholz 8:30 – 9:00 PDT in veterinary medicine - UPDATE

OS-12-01 Jane Dobson University of Cambridge, GBR

9:00 – 9:15 PDT for transitional cell carcinoma of the bladder in dogs OS-12-02 Arno Roos

Veterinair Verwijscentrum Gouda, NLD 9:15 – 9:30 Photodynamic Antibacterial Treatment in Pets

OS-12-03 Katalin Kovacs Small Animal Laser Clinic,HUN

9:30 – 9:45 Efficacy of 5-aminolevulinic acid in photodynamic detection and photodynamic therapy in veterinary medicine OS-12-04 Tomohiro Osaki, K. Takahashi, M. Ishizuka, T, Tanaka, M. Yamashita, Y. Murahata, K. Azuma, T. Tsuka,N. Ito,T. Imagawa, Y. Okamoto

Tottori University, JPN

09:45 – 10:15 Break

Session 13 Future and Hot Topics Ronald Sroka, Herbert Stepp 10:15 – 10:45 PD and PDT in Neurosurgery – UPDATE

OS-11-01 Walter Stummer Universitätsklinikum Münster, DEU

10:45 – 10:55 Photodynamic Therapy of glioblastoma cells increases effector functions of CD8+ T cells OS-13-01 Simone Kreth

Klinikum der Universität München, DEU 10:55 – 11:05 Canine Glioblastoma- Translational Approach with Photodynamic Therapy

OS-13-02 Joe Impellizeri Veterinary Oncology Services, PLLC, USA

11:05 – 11:15 Design of Multifunctional Phototheranostics for Cancer OS-13-03 Pengfei Wang, Q. Jia, L: Guo, J. Ge

Chinese Academy of Sciences/University of Chinese Academy of Sciences, CHN 11:15 – 11:25 Singlet Oxygen Phosphorescence in vivo

OS-13-04 Steffen Hackbarth, M. Pfitzner, W. Islam, J. Fang, B. Röder Humboldt-Universität zu Berlin, DEU

11:25 – 11:35 Comparison between 8-methoxypsoralen and 5-aminolevulinic acid in killing T cells of photopheresis patients ex vivo OS-13-05 Odrun Gederaas, T. Holien, S. Ramesh Darvekar, E. Christensen, Q. Peng

Norwegian University of Science and Technology, NOR 11:35 – 11:45 The influence of photodynamic therapy with bacteriochlorins on the immune response

OS-13-06 Janusz Dabrowski, B. Pucelik, L. G. Arnaut Jagiellonain University, POL

Closing remarks

11:45 Ronald Sroka

Oktoberfest “O’zapft is” (tapping a wooden beer barrel) 12:00 sharp Live video showing the major of Munich in a beer tent tapping the first barrel


Saturday 22nd September

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Poster-Overview

Group 1:

Poster-number: 101 - 511 Hang-up Wed. 19th 07:45 - 08:30 Poster walk Thu. 20th 13:30 - 14:00 Removal Thu. 20th 15:00 - 17:30

Session 1 - Photosensitizers

101 Weimin Liu Chinese Academy of Sciences, China A Mitochondria-Targeted Photosensitizer for Photodynamic Therapy

102 Julien Massiot University Paris-Sud, France Lipid-porphyrin conjugates as potential multifunctional drug delivery systems

103 Shaimaa Alexeree National Institute of Laser Enhanced science, Egypt Exploiting biosynthetic gold nanoparticles for improving the aqueous solubility of metal-free phthalocyanine as biocompatible PDT agent

104 Luis Arnaut University of Coimbra, Portugal Low molecular weight carboxamide bacteriochlorins for topical treatment of skin cancers

105 Anderson Caires Universidade Federal de Mato Grosso do Sul, Brazil Evaluation of chlorophyllin sodium-copper as photosensitizer for Photodynamic control of Aedes aegypti larval population

106 Juhee Jeon Dongsung Bio Pharm, South Korea The Anti-Tumor effect of Sensitizers in Photodynamic and Sonodynamic Therapy

107 Sergey Kuzmin FSUE "SSC "NIOPIK", Russia Laser ablation of phthalocyanine nanoparticles in a liquid medium simulating tissue

108 Mariana Máčajová CBs SAS, Slovakia Hypericin topical delivery to the tumor and yeast cells – study on the quail CAM model

109 Bruno Nascimento University of Coimbra, Portugal Novel temoporfin-related 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-fused chlorins: synthetic details, structural characterization and cytotoxicity evaluation

110 Alexander Ponyaev Saint-Petersburg State Institute of Technology, Russia Xanthene Dyes with long-wave absorption for photodynamic therapy and diagnostics

111 Yelena Wainman Ludwig-Maximilians-Universität Munich, Germany Development of a light activated chemotherapeutic for the treatment of solid tumors

112 Jia-Ling Zou Shanghai University of Traditional Chinese Medicine, China Research advance of hypocrellin in photodynamic therapy

113 Lenka Lenkavská P. J. Safarik University, Slovakia Comparison of HDL and LDL lipoproteins as hypericin carriers in PDT


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Session 2 - Targeted PDT

201 Ludovic Bretin LABORATORY PEIRENE, France Analysis of new vectorized photosensitizers effects by using photodynamic therapy on colorectal cancer

202 Xiaosong Li The Second Hospital of Jilin University, China Application of optical coherence tomography angiography in vascular targeted photodynamic therapy of port wine stains

203 Marline N'Diaye University Paris-Sud, France Design of liponanoparticles for dual treatment of retinoblastoma by chemo/photodynamic therapy

204 Nelson A.M. Pereira University of Coimbra, Portugal Promising nanobody-ring-fused chlorin conjugate as potential agent for targeted photodynamic therapy of cancer

205 Abdul-Amir Yassine University of Toronto, Canada The Value of Customization: Photodynamic Therapy Planning with Tailored Diffusers

206 Zahraa Youssef LRGP-CNRS, France Development of New Titania- And Silica-Based Drug Carrier Nanosystems: In Vitro Assessment of the Anti-Cancer Efficiency on Glioblastoma

207 Philippe Arnoux CNRS - LRGP, France The Nancy’s PDTeam projects: targeted molecules for photodynamic therapy

208 Amina Ben Mihoub Université de Lorraine, France Targeted photodynamic therapy with glioblastoma cancer-specific peptide conjugated photosensitizer and cyclodextrin

209 Ying Gu Chinese PLA General Hospital, China Research progress of dosimetric monitoring technology for vascular targeting photodynamic therapy

210 Ewa Kowolik Uniwersytet Jagielloński, Poland Effects of vascular-targeted photodynamic therapy of human glioblastoma with theranostic AGuIX nanoparticles

211 Ludivine Larue LRGP-CNRS, France New Platforms for improving the treatment of glioblastoma by photodynamic therapy

212 Zaria Malindi University of Cape Town, South Africa Photoimmunotheranostic targeting of CSPG4-positive melanoma cells using SNAP-tag technology

213 Albert Moussaron Laboratoire de Chimie-Physique Macromoléculaire, France Diagnosis of brain metastases by Positron-emission tomography (PET): complementarity of dual targeting NRP-1 & LRP-1

214 Takahiro Nomoto Tokyo Institute of Technology, Japan Multiple cyclic RGD-conjugated functional polymers controlling intratumoral distribution of IRDye 700DX

215 Fleury Augustin Nsole Biteghe University of Cape Town, South Africa Photoimmunotheranostic treatment targeting EGFR positive melanoma cells

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216 Lluïsa Pérez-García University of Nottingham, United Kingdom Supramolecular hydrogels: new nanomaterials for PDT

217 Aimie Rendle University of Hull, United Kingdom Stimuli-Responsive Porphyrin Nanogels for Photodynamic Therapy of Cancer

219 Mingfeng Bai Vanderbilt University Medical Center, USA Overcoming Chemoresistance Using Tumor Mitochondria-targeted Photodynamic Therapy

220 Ramtin Rahmazadeh University of Lübeck, Germany Light controlled delivery of Photo-Immunoconjugates for molecular targeted PDT

Session 3 - Combinations in PD-PDT

301 Pilar Acedo University College London, United Kingdom Establishment of light-based combination strategies for treating pancreatic cancer

302 Jens Buentzel Südharz Klinikum Nordhausen GmbH, Germany Combined Photodiagnosis (PD) and Photodynamic Therapy (PDT) in Head Neck Cancer Patients

303 Cristina Kurachi University of São Paulo, Brazil Fluorescence lifetime imaging microscope to discriminate skin lesions

304 Jayoti Som Memorial University of Newfoundland, Canada Promotion of in vivo 5-ALA-PDT efficacy by MEK inhibition

305 Andrea Tabero Universidad Autónoma de Madrid, Spain Gold nanoclusters for light-controlled delivery of combined chemo and phototherapy.

306 Steven Yap University of Hull, United Kingdom Polyacrylamide nanoparticles: a conjugatable platform for use in the diagnosis and treatment of cancer

307 Daria Pominova Russian Academy of Sciences, Russia Fiber-optic technique for quantitative determination of the chlorin derivatives nanoparticles accumulation in the mice organs

308 Piotr Ziółkowski Wrocław Medical University, Poland Effect of 5-ALA mediated PDT in combination with thalidomide on murine breast carcinoma and endothelial cell lines


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Session 5a - Antimicrobial

501 Antonella Battisti Nanoscience Institute CNR, Italy An insight into endogenous porphyrin production by Helicobacter pylori

502 Anzhela Galstyan Center for Soft Nanoscience, Germany Advanced photoactive compounds and interfaces against microbial pathogens

503 Paola Morici Nanoscience Institute CNR, Italy In vitro photoinactivation of Helicobacter pylori by a novel LED-based device

504 Antonella Sgarbossa Nanoscience Institute CNR, Italy The photophysical characterization of Helicobacter pylori porphyrins as endogenous photosensitizers for antimicrobial photodynamic therapy

505 Cynthia Caires Universidade Federal de Mato Grosso do Sul, Brazil Photodynamic inactivation of mcr-1 positive E. coli

506 Elena de las Heras IQS - Universitat Ramon Llull, Spain Gentamicin-based photo-antimicrobials

507 Alessandra Nara de Souza Rastelli University of São Paulo State, Nbrazil A curcumin-loaded liquid crystal system used for antimicrobial photodynamic therapy over Streptoccocus mutans biofilm

508 Franco Fusi University of Florence, Italy The CapsuLight project: from in vitro studies to intra-gastric robotic device prototyping for antibacterial PDT against Helicobacter pylori

509 Mariana Geralde University of São Paulo, Brazil PDI with nebulized indocyanine green and infrared light for pneumonia treatment

510 Wan-Jun Guo Shanghai University of Traditional Chinese Medicine, China Study on Photodynamic Anti-infection of Forsythia Extract Hypericin

511 García Hally IQS - Universitat Ramon Llull, Spain Porgenta: a Novel Photosensitiser-Antibiotic Conjugate for aPDT

511a Natalia Masiera Polish Academy of Sciences, Poland Porphycenes as PDI agents. Structure and activity

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Group 2:

Poster-number: 512 - 1307 Hang-up Fri. 21st 07:45 - 08:30 Poster walk Fri. 21st 13:30 - 14:00 Removal Sat. 22nd after lunch

Session 5b - Antimicrobial

512 Carla Oliveira Federal University of Mato Grosso do Sul, Brazil Incorporation and photoactivity characterization of Crystal Violet in Aspergillus flavus

513 Aleksandra Rapacka-Zdonczyk University of Gdansk, Poland Could Staphylococcus aureus become more tolerant to oxidative stress after repeated exposure to sub-lethal doses of blue light? 514 Giovanni Romano University of Florence, Italy A side-effect study of intra-gastric antibacterial PDT

515 Jennifer Soares University of São Paulo, Brazil Influence of Formulation in Uptake of Photosensitizer by Bacteria

516 Amanda Zangirolami University of São Paulo, Brazil Inactivation of S. aureus biofilm applying photodynamic inactivation using nebulized curcumin

517 Tadeuz Sarna Jagiellonian University, Poland Possible role of peroxynitrate in antibacterial photodynamic inactivation mediated by rose Bengal and sodium nitrate

Session 6 - Physics

601 Mirian Stringasci University of São Paulo, Brazil Thermographic imaging during the PDT procedure to improve understanding of photodynamic mechanisms

602 Marek Scholz Charles University, Czech Republic Microscopic time-resolved imaging of singlet oxygen in cells using delayed fluorescence

603 Mirian Stringasci University of São Paulo, Brazil Interference of temperature in the production of PpIX using ALA and methyl-ALA

604 Stephan Ströbl Vorarlberg University of Applied Sciences, Austria New method to characterize the emission profile of radially emitting fiber diffusers

605 Timothy Zhu Univ of Pennsylvania, USA A comparison of in-vivo threshold doses among type I and II vascular-mediated

606 Emily Oakley Roswell Park Comprehensive Cancer Center, USA Finite Element Method (FEM) Guided Interstitial PDT with Consecutive Light Illumination

607 Max Aumiller Klinikum der Universität München, Germany Interstitial measurement of optical tissue properties for interstitial photodynamic therapy


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Session 7 - Mechanisms

701 Sylvestre Bonnet Leiden University, Netherlands Photoactivated chemotherapy in hypoxic cancer cells

702 Hilde Harb Buzza University of São Paulo, Brazil Tumor model in chorioallantoic membrane and the possibility to follow the photosensitizer from vessel to tumor with fluorescence analysis

703 Vipin Shankar Chelakkot Memorial University of Newfoundland, Canada 5-ALA-PDT triggers NLRP3 mediated pyroptosis

704 Leonardo Franchi University of Amsterdam/University of São Paulo, Netherlands Biological signaling properties induced by photodynamic therapy

705 Juliana Cabrini Carmello São Paulo State University, Brazil Cytotoxic effect of white LED light on human skin keratinocytes

706 Sviatlana Kalinina University of Ulm, Germany Monitoring of cell metabolism during PDT

707 Carsten Lange University of Greifswald, Germany Investigation of the Cell Death Mechanism after Temoporfin mediated Photodynamic Therapy (PDT) of five Human Cancer Cell Lines

708 Ana Claudia Pavarina São Paulo State University, Brazil Are blue LED lights safe enough for oral applications?

709 Jing Zeng Chinese PLA General Hospital, China In Vivo Study on Photo-thermal Effects during Vascular Target Photodynamic therapy for Port Wine Stains treatment

710 Irina Semenova Ioffe Institute, Russia Quantitative assessment of changes in cellular morphology after PD treatment in vitro. Correlation with cell death pathways

711 Joanna Zawacka-Pankau Karolinska Institutet, Sweden Activation of TAp73 and inhibition of thioredoxin reductase for improved

712 Hung Wei Lai Tokyo Institute of Technology, Japan Pivotal roles of transporters involved in aminolevulinic acid (ALA) uptake in ALA-induced PpIX accumulation in vitro

713 Veronika Huntosova P.J. Safarik University in Kosice, Slovakia Hypericin induced PDT applied to spheroids of cancer cells

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Session 8 - Immuno-PDT

801 Aleksandra Kawczyk-Krupka Medical University of Silesia, Poland The influence of ALA-mediated photodynamic therapy on secretion of selected growth factors, interleukins and s100 protein (S100) by colon cancer cells in vitro

802 Rainer Wittig University of Ulm, Germany Photodynamic activity of Temoporfin nanoparticles induces a shift to the pro-inflammatory M1-phenotype in polarized macrophages

803 Yuliya Maklygina Russian Academy of Sciences, Russia A novel spheroid model for studying intercellular photosensitizer-mediated tumour and immune cell communication.

804 Anastasia Ryabova Russian Academy of Sciences, Russia Tissues distribution of organic crystalline mTHPC nanoparticles on model inoculated tumors in vivo

Session 9 - Clinical Use 1

901 Thomas Giesen PiLight GmbH, Germany Clinical application of the photodynamic therapy for complex wounds of multifactorial genesis in medicine

902 Jie JI Shanghai Skin Disease Hospital, China ALA-PDT as a palliative care in a patient with secondary perineum EMPD

903 Wojciech Latos Specjalistyczna Praktyka Lekarska, Poland The benefits of targeted endoscopic biopsy performed using the autofluorescence based diagnostic technique in 67 cases of diagnostically difficult gastrointestinal tumors

904 Maxim Loshchenov Russian Academy of Sciences, Russia Fluorescence Image Analyzer for Intraoperative Use in Gastrointerology

905 Lei Shi Shanghai Skin Disease Hospital, China Combination of Photothermal and Immunoadjuvant for Refractory Cutaneous Warts

906 Artem Shiryaev I.M. Sechenov First Moscow State Medical University, Russia Combined treatment of non-resectable cholangiocellular cancer complicated with mechanical jaundice

907 Linglin Zhang Shanghai Skin Disease Hospital, China Improvement of photodynamic therapy by transdermal administration with plum blossom needle for the treatment of Bowen’s disease

908 Kate Blanco University of São Paulo, Brazil Study of a new option for treatment of streptococcal pharyngotonsillitis

909 Aleksandra Kawczyk-Krupka Medical University of Silesia, Poland Photodynamic therapy as an alternative to antibiotic therapy for the treatment of infected leg ulcers- pilot study

910 P.U. Turkin Pirogov Russian National Research Medical University, Russia Photodynamic therapy of venous ulcers

911 Jinyan Wang Ningbo No.2 Hospital, China A clinical trial using carbon dioxide laser combined with 5-aminolevulinic acids based photodynamic therapy in treating nasal basal cell carcinoma


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912 Min-Feng Wu Shanghai University of Traditional Chinese Medicine, China Photodynamic therapy for pediatric kerions: report of three cases

913 Luke McLellan University of Dundee, GBR Patient overview on the future of daylight photodynamic therapy

914 Maria Ziolkowska Ev. Elisabeth Klinik, Zentrum Lasermedizin, Germany OCT supported PDT- Case Report

Session 10 - Clinical Use 2

1001 Aleksandra Kawczyk-Krupka Medical University of Silesia, Poland ALA- Photodynamic treatment in Lichen sclerosus-clinical and immunological outcome focusing on the assesment of antinuclear antibodies

1002 Victor Loschenov Russian Academy of Sciences, Russia Clinical Spectral Fluorescence and Back-Scattering Study of Bladder Neoplasmes

1003 Haixia Qiu Chinese PLA General Hospital, China The application of Vascular Targeted Photodynamic Therapy in the Chinese PLA General Hospital

1004 Aleksander Sieroń Medical University of Silesia, Poland Photodiagnosis and Photodynamic therapy in Center for Laser Diagnostics and Therapy in Bytom, Poland- a new directions

1005 Zheng Huang Fujian Normal University, China Quantitative analysis of PWS birthmark color in PDT treatment

Session 13 - Future and Hot Topics 1301 Jaroslava Joniova Swiss Federal Institute of Technology, Switzerland Use of photobiomodulation to improve PpIX-PDT in vivo

1302 Eduard Mahiliavets Grodno State Medical University, Belarus Influence of photodynamic therapy on processes of liver regeneration at cirrhosis

1303 Georges Wagnières Swiss Federal Institute of Technology, Switzerland Physico-chemical study of the protoporphyrin IX delayed fluorescence to quantify the pO2 in biological tissues

1304 Thierry Michy Service de Chirurgie Gynécologique, France Fluorecence-guided surgery of ovarian carcinomatosis: Angiostamp800™ vs Indocyanine green

1305 Shun-ichiro Ogura Tokyo Institute of Technology, Japan Applications of Aminolevulinic acid in tumor – From Diagnosis and Therapy to Screening

1306 Christian Heckl Klinikum der Universität München, Germany Rapid spectrophotometric quantification of urinary porphyrins and porphobilinogen as screening tool for attacks of acute porphyria

1307 Herbert Stepp Klinikum der Universität München, Germany Fluorescence guided stereotactic biopsy of malignant glioma

The poster overview may be subject to change at short notice.

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Welcome to PDT & PD Update 2018pdt2018.com/.../uploads/2018/09/Conference-Booklet.pdf · 2018. 10. 8. · 2 Welcome to PDT & PD Update 2018 . following the tradition initiated in