Volume 8, Year 2008, Keyword Index. - · PDF fileFinite-element 379 Flexural Rigidity 401 Fluoxetine 121 Forearm Bone Mass 196 Fracture 133, 329, 379 ... Econs, MJ 284, 357 Einhorn,

418

AAcute Phase Proteins 410Adaptation 10Adipocyte 146Adipokines 346Adrenergic Receptors 105Adrenergic Signaling 94AFM 330Ageing 64Aging 2, 329, 50, 410Alfacalcidol 257Angiogenesis 323Animal and Human Studies 94Animal Models 301Anorexia Nervosa 315Anthropometric Parameters 363Antidepressants 121Atrophy 342Atrophy Target Genes 340

B‚-adrenergic Signalling 111‚-catenin 291B6 71Bcl-3 340Biomechanics of Leg 58BMP4 316Body Weight 146Bone 10, 12, 25, 50, 111, 166, 179, 298, 318, 329, 330, 337,344, 346Bone Adaptation 15, 71Bone Cell Integrins 332Bone Cells 15Bone Density 2, 22, 79, 133Bone Fluid Flow 332Bone Geometry 217Bone Histomorphometry 267Bone Mass 146, 363 Bone Material 29Bone Mechanics 327Bone Mineral Density 217, 315Bone Phenotyping 13Bone Quality 325Bone Regeneration 323Bone Remodeling 2, 29, 94Bone Resorption 251Bone Shape 23Bone Size 217Bone Strength 22, 33, 239, 267Bone Turnover 24Bone-marrow Interface 43

CC3 71Cartilage 307, 308, 321, 337Cartilage Degradation 301Cell Signaling 303CGRP 154Children 24, 25, 217Chondrocyte 303Chondrocytes 307Clinical Research 313Clinical Trials 2Commitment 204Compression 227Computational Mechanics 327Congenic 287Cortical Bone 146Crohn’s disease 79Cross-sectional Muscle Area 239CT 315CTR Polymorphisms 196Cynomologus Monkeys 267Cystic Fibrosis 179Cytokines 301

DD2 71Deformities 58Depression 133Diabetes 346Differentiation 204Diphosphonates 2Distal Tibia 257Distraction Osteogenesis 323Disuse 12DKK-1 296DXA 24, 32, 315

EElbow 391Electrical Stimulation 227Energy Balance 344Energy Dissipation 329Energy Metabolism 351Epidemiology 313Epimedium 18Esp 351Exercise 12, 35, 166Extracellular Matrix 311

JJoouurrnnaall ooff MMuussccuulloosskkeelleettaall && NNeeuurroonnaall IInntteerraaccttiioonnssJJoouurrnnaall ooff MMuussccuulloosskkeelleettaall && NNeeuurroonnaall IInntteerraaccttiioonnss

Official Journal of the International Society of Musculoskeletal and Neuronal Interactions

Volume 8, Year 2008, Keyword Index.

419

FFailure Load 401Falls 244Fat 344, 346Fatty (Yellow) Marrow Site 257Females 391Femur 25Fibroblast Growth Factor 318Finite-element 379 Flexural Rigidity 401Fluoxetine 121Forearm Bone Mass 196Fracture 133, 329, 379Fractures 244Functional Adaptation 298

GGender 337Genetics 10, 284, 287Geometrical Variables 196GIP 344, 348GLP 344GLP-2 348Glutamate 166Glycosylated Hemoglobin 188Growth 25, 338Growth Factors 301Growth Plate 29, 308

HHBM 294Hematopoietic (Red) Marrow Site 257Histomorphology 18Histomorphometry 25717‚-Hydroxysteroid Dehydrogenase Type 2 Inhibitor 267Hypertrophy 308, 342Hypoxia Inducible Factor-1· 323

IIGF-1 303IGF1 335IGF-I 342IkappaB Kinases 340IL-1ß 307Ilizarov 32Image Analysis 23In Utero 12Inbred Strain 287Incretin 348Inflammatory Bowel Disease 79, 251Inhibitor of KappaB 340Integrins 303

JJoint 174Joint Position Sense 391

KKnee 313

LLacunar Canalicular Porosity 332Leptin 146, 351Ligament Forces 58Light Orthodontic Forces 375Limb Length Discrepancy 32Liver 410LRP5 284, 291LRP-5 296Lrp5 G171V 294LRP6 291

MMale 196MAP Kinase 311Marrow Sac 43Marrow Stromal Cell 43Master Athletes 64Mathematical Modeling 15Maxillary Cortical Bone 375Maximal Isometric Grip Force 188Mechanical Loading 71, 111, 311Mechanical Strain 298, 338Mechanography 64Mechanostat 298Mechanostat Theory 174Mechano-transduction 15Mechanotransduction 332Memory 166Metabolism 344Metalloproteinases 301Mice 71Micro-angiography 18MicroCT 18microRNA140 321Modeling 29Moment 401Motor Control 174Mouse 13Mouse Clinic 13Msx2 318mTOR 335Muscle 25, 64, 179Muscle Area 33Muscle Derived Stem Cells 316Muscle Power 33Muscle Stem Cells 337Muscle Strength 35, 363 Muscle Wasting 340Muscle-bone 239Muscle-derived Stem Cells 335Musculoskeletal Physiology 64Myoblast 342Myostatin 342

420

NNanomechanics 325, 327, 330Neurotransmitter 121NF-kB 335NO 15Nocturnin 344Nuclear Factor of KappaB 340Nutrition 344

OOA 311OC-cre 291Osteoarthritis 22, 35, 301, 307, 313, 316, 391Osteoblast 94, 105, 348Osteoblasts 154, 351Osteocalcin 344, 351Osteoclast 94, 348Osteoclasts 154, 204Osteocyte Processes 332Osteocytes 15, 330Osteonecrosis 18Osteopaenia 251Osteoporosis 2, 22, 50, 79, 105, 121, 133, 174, 179, 204, 267,284, 287Osteoprotegerin 50Ovariectomy 375

PPain 35Peak Bone Mass 196Peak Jump Force 188Peak Jump Power 188Periosteum 29Peripheral Quantitative Computed Tomography 217, 227PGE2 15Physical Activity 363 Post-yield 329PPARÁ 344, 346PQCT 23, 239, 401Preosteoblast 43Pre-pubertal 239Propranolol 111Proprioception 35, 391Protein Synthesis 338Protein Synthesis Rate 410Proximal Femur 257Prozac 121Pyrophosphate 318

QQuantitative Trait 287

RRadiographs 379Rats 375Reactive Oxygen Species 303Rehabilitation 244

Rel Protein 340Risk Factors 2Runx2 318

SS6K1 338Satellite Cell 342Scaling 25Selective Serotonin Reuptake Inhibitors 133SFRP-1 296Skeletal Muscle 337, 410Skeletal Mutations 294Skeleton 24SNS 111SOST/Sclerostin 296SP 154Spinal Cord Injury 50Steroid 18Steroids 24Stiffness 401Strength Indices 401Stress State 58Sympathetic Nervous System 105

TTemporary Brittle Bone Disease 379Tension 227Thiazolidinediones 346Trabecular Structure 315Transgenic 287Transgenic Model 251Transgenic Mouse 311Treatment 204Type II Collagen 308

UUlcerative Colitis 79Ultrastructure 325, 327

VValgosity 58Varosity 58VDR Polymorphisms 196VEGF 316, 323VIP 154von Hippel-Lindau Protein 323VO2max 363

WWhole Body Vibration 179Wnt 291, 296Wnt Signaling 294WWP2 321

ZZinc 22

421

AÅhlander, A-C 24Abe, K 13Acosta, F 355Akhter, MP 71Alaql, ZS 323Ali, MN 352Allgöwer, F 15Antonogiannakis, E 196Antvorskov, T 64Anwar, RB 352, 361, 362Anyanwu, J 353Armbrecht, G 179

BBagi, CM 267Baile, CA 146Baker, LRI 355Bamman, MM 342Bartell, SM 146Battaglino, RA 50Behan, M 360Beller, G 179Bérard, J 32Bi, LX 43Binkley, T 33Binkley, TL 239Bliddal, H 391Blimkie, C 25Bliziotes, M 93Block, JA 35Bodine, PVN 296Bonewald, LF 330, 352Bonivitch, AR 330Bonivtch, AR 352Bonnet, N 94Boshof, A 64Bouxsein, M 357Braillon, P 32Bredella, MA 315Breuillé, D 251, 410Brown, RJ 354Bubbear, JS 355Buford, WL 43Bunn, C 356Burr, DB 281

CCao, XM 323Capozza, R 355

Castellini, P 355Causey, RC 360Cerny, EP 58Charopoulos, I 196Chen, HY 257Chen, Q 311Chenu, C 111Chotel, F 32Christensen, H 391Christensen, PH 22Christensen, R 391Christiansen, C 357Ciccomancini, M 357Clemens, TL 291, 323Cockrell, G 356Cointry, G 355Coonse, KG 354Cooper, GM 316Cowell, C 25Coxam, V 251Cross, RA 360Culik, J 58Cullen, DM 71

DDanneskiold-Samsoe, B 391Davicco, M-J 251Davis, SI 355de Bono, S 23Dedoussis, G 196Deng, L 323Dionyssiotis, Y 244Dixon, B 267Dontas, IA 244, 375Dowthwaite, JN 355Dudley-Javoroski, S 227Dusecich, V 330

EEberhardt, AW 323Economides, AN 357Economopoulos, D 244Econs, MJ 284, 357Einhorn, TA 323Ejiri, S 352, 361, 362El Yousfi, M 251Engelke, K 363Esser, K 335, 338



Volume 8, Year 2008, Author Index.

422

FFarrow, EG 355Feldman, S 355Felsenberg, D 64, 179Feng, JQ 330Ferrari, SL 94Ferretti, JL 355Findeisen, R 15Fosang, AJ 308Fowlkes, J 356Fox, SD 71Franceschi, RT 318Fricke, O 188Fritz, TA 357Fu, FH 316Fuchs, H 13Furmanov, S 35

GGailus-Durner, V 13Galanos, A 196Garshick, E 50Gast, U 64Gauci, SJ 308Gerstenfeld, LC 323Gharaibeh, B 316Gilbert, SR 323Gillespie, M 357Godin, J-P 251Golub, SB 308Goodship, AE 10Grappiolo, I 355Griffith, JF 18Guldberg, RE 323Gundberg, CM 360Guo, XE 325, 327Gupta, R 315

HHadjidakis, D 79Halteman, WA 360Hamrick, M 348Hamrick, MW 146Haney, EM 121, 133Hangartner, TN 379Hans, W 13Hansen, K 391Hatch, NE 318Hausler, KD 357He, X 321Henriksen, K 357, 360Hickman, RM 355Hoeck, HC 22Högler, W 24Hrabe de Angelis, M 13

Huang, L 357Huard, J 316, 337Hui, SL 357

IIchikawa, S 357Inchauspe, G 355Isales, CM 146, 348Iwamoto, J 358

JJacobsen, KA 323Jain, N 50Jakubas, WJ 360Jarret, A-R 410Järvinen, TLN 2Jee, WSS 257Jiang, JX 352Johnston, JD 401Jung, T 64Juul-Kristensen, B 391

KKalender, WA 363Kandarian, S 340Kannus, P 2Karamanolis, DG 79Karlsson, J 24Karsdal, MA 357Karsenty, G 351Keen, R 355Kemmler, W 363Khaldi, L 375Kladny, B 363Klein, RF 287Klibanski, A 315Kobayashi, T 321Kontulainen, SA 401Kopylov, D 353Kroksmark, A-K 24Kuhar, MJ 146Kuruvilla, SJ 71Kvetnansky, R 353Kwiet, A 64Kyriazopoulos, P 196

LLadas, SD 79Lane, N 330Lanyon, L 298Laskey, MA 23Laskey, PJ 23Laursen, MB 22Lecka-Czernik, B 344, 346Lee, ER 308

423

Lee, NK 351Lerner, UH 154Lester, G 313Leung, C 401Leung, KS 18Li, B 359Li, G 316Li, J 359Li, M 257Li, Y 35Li, ZR 18Lindvall, C 291Ling, J 352Lisse, T 13Little, CB 308Liu, D 359Liu, D 401Liu, X 358Liu, XQ 257Loeser, RF 301, 303Long, R 360Lumpkin, C 356Lund, H 391Lyritis, GP 196, 244, 375

MMackenzie, DS 357Mackie, EJ 308Magnusson, P 24Mainous, EG 43Makou, M 375Maldonado, S 15Mallas, E 79Marenzana, M 111Marik, I 58Martin, TJ 357Matsumoto, H 358Matsumoto T, 316Mayot, G 410McKay, HA 401McNamara, LM 332Mermoud, A-F 251Meszaros, LB 316Michaelis, I 64Miletic, V 360Miller, KK 315Miller, ME 379Misra, M 315Moh, A 357Moravits, DE 330Morse, LR 50Muir, P 360Murphy, A 357Møller-Madsen, B 22

NNakamura, Y 321Nelson, DE 35Neutzsky-Wulff, AV 357Nguyen, HP 50Nicola, G 355Nicolella, DP 330, 352Nielsen, PT 22Nomura, S 361, 362Nyman, J 356

OObled, C 251, 410Ohshima, H 352, 361, 362Ovesen, J 22Oxford, JT 354Oxland, TR 401

PPanus, DA 357Papet, I 251, 410Patterson-Buckendahl, PE 353Persson, E 154Pierroz, DD 94Postlethwait, JH 321Prentice, A 23

QQin, L 18

RRadice, B 355Ramaswamy, G 323Rao, N 359Rauch, F 25, 29, 217Rawer, R 179Raz, R 357Recker, RR 294Reid, IR 105Reina, P 355Rembitzki, I 179Rittweger, J 64, 174Robling, A 359Rosen, CJ 360Rosen, V 357Roth, J 179

SSakurai, N 362Sample, SJ 360Sandel, LJ 307Sanders, AK 291Scerpella, TA 355Schaffler, MB 332Schiessl, H 1Schnabel, D 179

424

Schoenau, E 188, 217Schöffl, I 363Seewi, O 188Seger, RL 360Seger, RM 360Semler, O 188Servello, FA 360Setterberg, RB 257Shah, A 353Shahid, M 353Shakoor, N 35Shaw, CN 23Shen, X 323Sheng, H 18Shields, RK 227Shimakura, T 361Sievänen, H 2Simonsen, O 22Sims, NA 308Skerry, T 12Skerry, TM 166Söderpalm, A-C 24Song, F 359Sorenson, AH 357Spadaro, JA 355Specker, B 33Specker, BL 239Spyropoulos, MN 375Staab, D 179Stabrey, A 188Stamp, TCB 355Stashenko, P 50Stathopoulou, M 196Stocum, D 359Summers, LJ 355Swolin-Eide, D 24

TTakahashi, HE 361Tanaka, M 352, 361, 362Thiele, F 13Thomsen, JS 22Thrailkill, K 356Tian, XY 257Trovas, G 196Tsironi, E 79Tsolakis, AI 375Tulinius, M 24Tun, CG 50Tutlewski, B 188Tutolo, L 308Tzathas, C 79

UUsas, A 316

VValenzuela, DM 357Van Dyke, ME 352VanKoevering, KK 291Varghese, BA 379Vitenzon, A 353von Stengel, S 363

WWagoner Johnson, AJ 358Wahl, E 356Wahn, U 179Wan, C 291, 323Wang, X 329Wang, XL 18Wang, Y 323, 330, 332Wang, YX 18Ward, LM 355Warden, SJ 121, 133Warman, ML 321Watanabe, N 352Weinbaum, S 332White, KE 355Wilkie, D 267Williams, BO 291Williams, S 50Willnecker, J 1Wilson, AP 360Wood, J 267Woodhead, H 25Wust, M 179

XXue, Y 357

YYamamoto, N 361Yamashita, E 352, 361, 362Yan, Y-L 321Yancopoulos, GD 357Yao, W 330Yao, XS 18Yavropoulou, MP 204Yeh, JK 358Yeung, KW 18Yngve, DA 43Yovos, JG 204

ZZhang, G 18Zhu, D 23Zylstra, CR 291

425



Aaron, Roy (1)Arnaud, Claude (1)Behrents, Rolf (1)Bergmann, Pierre (1)Bonnet, Nicolas (1)Chenu, Chantel (1)Dale R. Sumner (1)De Vernejoul, Marie-Christine (1)Degens, Hans (3)Dempster, David (1)Devogelaer, Jean-Pierre (3)Diem, Susan (1)Drake, Matthew (1)Dontas, Ismene (2)Elefterious, Florent (1)Ferrari, Serge (1)

Ferretti, José L. (1)Forwood, Mark (1)Goltzman, David (1)Hamrick, Mark (2)Hans, Mark (1)Heinonen, Ari (1)Iwaniec, Urszula (1)Karras, D (1)Ke, Huazhu (1)Kimmel, Don (1)Krohn, Kelly (1)Lu, Shi Shu (1)Mezuk, Briana (1)Mikesky, Alan (1) Moutsatsou, Paraskeui (1)Papavassiliou, Athanasios (1)

Peacock, Munro (2)Rauch, Frank (1)Reeves, Neil (1)Rittweger, Joern (1)Robling, Alex (2)Runge, Martin (1)Seeman, Ego (1)Skelton, Dawn (1)Specker, Bonny (1)Stayrook, Keith (1)Tournis, Symeon (1)Trovas, George (1)Tsezou, Aspasia (1)Weinans, Harrie (1)Yao, Wei (2)Yiannakopoulos, Christos (1)

Volume 8, Year 2008, Reviewer Index.

( ) number of publications reviewed

426

Volume 8, Number 1, January-February-March 2008

ForewordJ. Willnecker, H. SchiesslThe 4th Black Forest Forum for Musculoskeletal Interactions .... 1

Black Forest Forum, May 10-13, 2007, Castle BadLiebenzell, Germany

T.L.N. Järvinen, P. Kannus, H. SievänenBone quality: Emperor’s new clothes ............................................ 2

A.E. GoodshipGenetically modified mechanostats: Implications for skeletal competence? .................................................................................. 10

T. SkerryMechanostat function during skeletal development .................. 12

H. Fuchs, T. Lisse, W. Hans, K. Abe, F. Thiele, V. Gailus-Durner,M. Hrabe de AngelisPhenotypic characterization of mouse models for bone-related diseases in the German Mouse Clinic .......................................... 13

S. Maldonado, R. Findeisen, F. AllgöwerDescribing force-induced bone growth and adaptation by a mathematical model ...................................................................... 15

L. Qin, G. Zhang, H. Sheng, X.L. Wang, Y.X. Wang, K.W. Yeung,J.F. Griffith, Z.R. Li, K.S. Leung, X.S. YaoPhytoestrogenic compounds for prevention of steroid-associated osteonecrosis .................................................................................. 18

J.S. Thomsen, P.T. Nielsen, P.H. Christensen, O. Simonsen, H.C. Hoeck, M.B. Laursen, B. MØller-Madsen, J. OvesenDifferences in zinc status, bone turnover and femoral head bonedensity and biomechanical properties between patients with osteoarthritis and osteoporosis .................................................... 22

S. de Bono, M.A. Laskey, C.N. Shaw, D. Zhu, P.J. Laskey, A.PrenticeCould image analysis of pQCT scans provide additional informa-tion about bone strength? .............................................................. 23

A-C. Söderpalm, P. Magnusson, A-C. Åhlander, J. Karlsson, A-K. Kroksmark, M. Tulinius, D. Swolin-EideBone markers and bone mineral density in Duchenne musculardystrophy ........................................................................................ 24

W. Högler, C. Blimkie, F. Rauch, H. Woodhead, C. CowellScaling and adjusting growth-related data and sex-differences in the muscle-bone relation: A perspective ................................ 25

F. RauchHistomorphometric evaluation of skeletal development .......... 29

P. Braillon, F. Chotel, J. BérardLimb lengthening: Contribution of dual energy X-ray absorptiometry ................................................................................ 32

T. Binkley and B. SpeckerMuscle area, muscle mass and muscle power in a pre-pubertal and an elderly population .............................................................. 33

Original ArticlesN. Shakoor, S. Furmanov, D.E. Nelson, Y. Li, J.A. BlockPain and its relationship with muscle strength and proprioception in knee OA: Results of an 8-week home exercise pilot study .... 35

L.X. Bi, E.G. Mainous, D.A. Yngve, W.L. BufordCellular isolation, culture and characterization of the marrow sac cells in human tubular bone .................................................... 43

L.R. Morse, H.P. Nguyen, N. Jain, S. Williams, C.G. Tun, R.A. Battaglino, P. Stashenko, E. GarshickAge and motor score predict osteoprotegerin level in chronicspinal cord injury ............................................................................ 50

J. Culik, I. Marik, E.P. CernyBiomechanics of leg deformity treatment .................................... 58

I. Michaelis, A. Kwiet, U. Gast, A. Boshof, T. Antvorskov, T. Jung,J. Rittweger, D. Felsenberg

Decline of specific peak jumping power with age in master runners ................................................................................ 64

S.J. Kuruvilla, S.D. Fox, D.M. Cullen, M.P. AkhterSite specific bone adaptation response to mechanical loading .. 71

E. Tsironi, D. Hadjidakis, E. Mallas, C. Tzathas, D.G.Karamanolis, S.D. LadasComparison of T- and Z-score in identifying risk factors of osteoporosis in inflammatory bowel disease patients ................ 79

Volume 8, Number 2, April-May-June 2008

ForewordM. Bliziotes ...................................................................................... 93

Review ArticlesN. Bonnet, D.D. Pierroz, S.L. FerrariAdrenergic control of bone remodeling and its implications for the treatment of osteoporosis ...................................................... 94



Volume 8, Year 2008, Volume Contents.

427

I.R. ReidEffects of beta-blockers on fracture risk .................................... 105

Mini-review ArticleM. Marenzana and C. ChenuSympathetic nervous system and bone adaptive response to its mechanical environment ........................................................ 111

Review ArticlesS.J. Warden and E.M. HaneySkeletal effects of serotonin (5-hydroxytryptamine) transporter inhibition: Evidence from in vitro and animal-based studies .. 121

E.M. Haney and S.J. WardenSkeletal effects of serotonin (5-hydroxytryptamine) transporter inhibition: Evidence from clinical studies .................................. 133

Original ArticleS.M. Bartell, C.M. Isales, C.A. Baile, M.J. Kuhar, M.W. HamrickCART deficiency increases body weight but does not alter bone strength .......................................................................................... 146

Review ArticlesU.H. Lerner and E. PerssonOsteotropic effects by the neuropeptides calcitonin gene-relatedpeptide, substance P and vasoactive intestinal peptide ............ 154

T.M. SkerryThe role of glutamate in the regulation of bone mass and architecture .................................................................................. 166

Mini-review ArticleJ. RittwegerTen years muscle-bone hypothesis: What have we learned so far? -Almost a Festschrift- .................................................................... 174

Original ArticlesJ. Roth, M. Wust, R. Rawer, D. Schnabel, G. Armbrecht, G. Beller, I. Rembitzki, U. Wahn, D. Felsenberg, D. StaabWhole body vibration in cystic fibrosis – a pilot study .............. 179

O. Fricke, O. Seewi, O. Semler, B. Tutlewski, A. Stabrey, E.SchoenauThe influence of auxology and long-term glycemic control on muscle function in children and adolescents with type 1 diabetesmellitus .......................................................................................... 188

I. Charopoulos, G. Trovas, M. Stathopoulou, P. Kyriazopoulos, A. Galanos, G. Dedoussis, E. Antonogiannakis, G.P. LyritisLack of association between vitamin D and calcitonin receptorgene polymorphisms and forearm bone values of young Greekmales .............................................................................................. 196

Volume 8, Number 3, July-August-September 2008

Original ArticlesM.P. Yavropoulou and J.G. YovosOsteoclastogenesis - Current knowledge and future perspectives .............................. 204

F. Rauch and E. SchönauPeripheral quantitative computed tomography of the proximal radius in young subjects – New reference data and interpretation of results ........................................................................................ 217

S. Dudley-Javoroski and R.K. ShieldsAsymmetric bone adaptations to soleus mechanical loading after spinal cord injury ................................................................ 227

T.L. Binkley and B.L. SpeckerMuscle-bone relationships in the lower leg of healthy pre-pubertal females and males .................................................. 239

Review ArticleY. Dionyssiotis, I.A. Dontas, D. Economopoulos, G.P. LyritisRehabilitation after falls and fractures ...................................... 244

Original ArticlesI. Papet, M. El Yousfi, J-P. Godin, A-F. Mermoud, M-J. Davicco, V. Coxam, D. Breuillé, C. ObledHLA-B27 rats develop osteopaenia through increased bone resorption without any change in bone formation .................... 251

X.Y. Tian, X.Q. Liu, H.Y. Chen, R.B. Setterberg, M. Li, W.S.S. JeeGreater efficacy of alfacalcidol in the red than in the yellow marrow skeletal sites in adult female rats .................................. 257

C.M. Bagi, J. Wood, D. Wilkie, B. DixonEffect of 17‚-hydroxysteroid dehydrogenase type 2 inhibitor onbone strength in ovariectomized cynomolgus monkeys ............ 267

Volume 8, Number 4, October-November-December 2008

ForewordD.B. BurrThe 38th International Sun Valley Workshop on Skeletal Tissue Biology ................................................................ 281

Genetics of Osteoporosis SessionSummaryM.J. EconsIntroduction to skeletal genetics ................................................ 284

R.F. KleinGenetics of osteoporosis – Utility of mouse models ................ 287

C.R. Zylstra, C. Wan, K.K. VanKoevering, A.K. Sanders, C. Lindvall, T.L. Clemens, B.O. WilliamsGene targeting approaches in mice: Assessing the roles of LRP5 and LRP6 in osteoblasts .................................................. 291

R.R. ReckerAutosomal dominant high bone mass: The phenotype. A brief description ...................................................................... 294

P.V.N. BodineTurning genetic discoveries into new treatments: The Wnt/LRP-5 system as a source of new drug targets for skeletaldiseases .......................................................................................... 296

428

RIB Award / Plenary SessionL. LanyonStrain-related control of bone (re)modeling: objectives, mechanisms and failures .............................................................. 298

Translational Research in OA - From Molecules to Animalsto Humans SessionSummaryR.F. LoeserTranslational research in osteoarthritis - From molecules to animals to humans ........................................................................ 301

R.F. LoeserMolecular mechanisms of cartilage destruction in osteoarthritis ................................................................................ 303

L.J. SandellMetabolism of chondrocytes in osteoarthritis: Why all this activity? .................................................................... 307

S.J. Gauci, S.B. Golub, L. Tutolo, C.B. Little, N.A. Sims, E.R. Lee, E.J. Mackie, A.J. FosangModulating chondrocyte hypertrophy in growth plate and osteoarthritic cartilage ................................................................ 308

Q. ChenMouse models and new therapeutic targets for OA ................ 311

G. LesterClinical research in OA – the NIH Osteoarthritis Initiative .......... 313

ASBMR / Harold M. Frost Award PresentationsM.A. Bredella, M. Misra, K.K. Miller, A. Klibanski, R. GuptaTrabecular structure analysis of the distal radius in adolescent patients with anorexia nervosa using ultra high resolution flat panel based volume CT .............................................................. 315

T. Matsumoto, G.M. Cooper, B. Gharaibeh, L.B. Meszaros, G. Li, A. Usas, F.H. Fu, J. HuardBlocking VEGF as a potential approach to improve cartilage heal-ing after osteoarthritis .................................................................. 316

N.E. Hatch and R.T. FranceschiFGF2 induced expression of the pyrophosphate generating en-zyme, PC-1, is mediated by Runx2 and Msx2 ............................ 318

Y. Nakamura, X. He, T. Kobayashi, Y-L Yan, J.H. Postlethwait,M.L. WarmanUnique roles of microRNA140 and its host gene WWP2 in cartilage biology ............................................................................ 321

C. Wan, S.R. Gilbert, Y. Wang, X.M. Cao, X. Shen, G. Ramaswamy, K.A. Jacobsen, Z.S. Alaql, L.C. Gerstenfeld, T.A. Einhorn, A.W. Eberhardt, L. Deng, R.E. Guldberg, T.L. ClemensRole of hypoxia inducible factor-1· pathway in bone regeneration .................................................................................. 323

Nanomechanics of Bone SessionSummaryX.E. GuoNanomechanics and bone tissue quality .................................... 325

X.E. GuoWhat is nanomechanics of bone and why is it important? ............ 327

X. WangThe post-yield behavior of bone: From nano to macroscopic length scales .................................. 329

D.P. Nicolella, J.Q. Feng, D.E. Moravits, A.R. Bonivitch, Y. Wang, V. Dusecich, W. Yao, N. Lane, L.F. BonewaldEffects of nanomechanical bone tissue properties on bone tissue strain: Implications for osteocyte mechanotransduction .......... 330

Y. Wang, L.M. McNamara, M.B. Schaffler, S. WeinbaumStrain amplification and integrin based signaling in osteocytes ...................................................................................... 332

Muscle Biology Session SummaryK. EsserRegulation of skeletal muscle size, regeneration and repair ........ 335

J. HuardRegenerative medicine based on muscle stem cells .................. 337

K. EsserRegulation of mTOR signaling in skeletal muscle hypertrophy .................................................................................. 338

S. KandarianThe molecular basis of skeletal muscle atrophy – parallels with osteoporotic signaling .......................................... 340

M.M. BammanRegulation of muscle size in humans: Role of myostatin? .......... 342

Bone as an Endocrine Organ SessionSummaryB. Lecka-CzernikBone as an integral part of energy metabolism ........................ 344

B. Lecka-CzernikLocal and systemic functions of bone fat and its contribution to the energy metabolism – The effect of diabetes and obesity on bone .......................................................................................... 346

C.M. Isales and M. HamrickNutritional hormones and the entero-osseous axis .................. 348

N.K. Lee and G. KarsentyReciprocal regulation of bone and energy metabolism ............ 351

Poster abstracts from the 38th Meeting of the International SunValley Workshop on Skeletal Tissue Biology (August 3-6, 2008, Sun Valley, Idaho, USA) ............................ 352

I. Schöffl, W. Kemmler, B. Kladny, S. von Stengel, W.A. Kalender,K. EngelkeIn healthy elderly postmenopausal women variations in BMD and BMC at various skeletal sites are associated with differencesin weight and lean body mass rather than by variations in habitualphysical activity, strength or VO2max ........................................ 363

429

A.I. Tsolakis, L. Khaldi, M. Makou, G.P. Lyritis, M.N. Spyropoulos,I.A. DontasCortical bone response adjacent to applied light orthodontic forces in ovariectomized rats ...................................................... 375

B.A. Varghese, M.E. Miller, T.N. HangartnerEstimation of bone strength from pediatric radiographs of theforearm .......................................................................................... 379

H. Lund, B. Juul-Kristensen, K. Hansen, R. Christensen, H. Christensen,B. Danneskiold-Samsoe, H. BliddalMovement detection impaired in patients with knee osteoarthritis compared to healthy controls: A cross-sectional case-control study .......................................... 391

S.A. Kontulainen, J.D. Johnston, D. Liu, C. Leung, T.R. Oxland,H.A. McKayStrength indices from pQCT imaging predict up to 85% of variance in bone failure properties at tibial epiphysis and diaphysis ........................................................................................ 401

G. Mayot, D. Breuillé, A-R. Jarret, C. Obled, I. PapetSystemic low-grade inflammation does not decrease skeletal muscle mass and protein synthesis in old rats .......................... 410

Index of Volume 8 ........................................................................ 418

Documents

Volume 8, Year 2008, Keyword Index. - · PDF fileFinite-element 379 Flexural Rigidity 401 Fluoxetine 121 Forearm Bone Mass 196 Fracture 133, 329, 379 ... Econs, MJ 284, 357 Einhorn,