Vitamin Presentation Thiamin-vitamin B1

Leshone Jackson and Jennifer Soto

Thiamin Thiamin is one of the B vitamins.

The B vitamins are a group of water-soluble vitamins that are part of many of the chemical reactions in the body.

Thiamin

Sources of Thiamin Thiamin is available in many dietary supplements.

Multivitamin/ multimineral supplements with thiamin typically provide about 1.5 mg thiamin (100% of the DV) and sometimes more. Supplements containing B-complex vitamins including thiamin. The most commonly used forms of thiamin in supplements are thiamin mononitrate.

Thiamine mononitrate is a stable nitrate salt form of thiamine (vitamin B1). It occurs as a white crystalline powder and is prepared from thiamine hydrochloride. It is used as a food or nutritional supplement and is the preferred form of the vitamin for food fortification), and thiamin hydrochloride, which are stable and water soluble.

Benfotiamine is a synthetic thiamin derivative that is used in some dietary supplements. Benfotiamine is not water soluble and is converted to thiamin in the body. Benfotiamine is a relative of the vitamin Thiamine (B1) that appears to have a therapeutic role in pain reduction and diabetic complications

Sources of Thiamin Food sources of thiamin include whole

grains, meat, and fish. Breads, cereals, and infant formulas in the United States and many other countries are fortified with thiamin. The most common sources of thiamin in the U.S. diet are cereals and bread Pork is another major source of the vitamin. Dairy products and most fruits contain little thiamin About half of the thiamin in the U.S. diet comes from foods that naturally contain thiamin; the remainder comes from foods to which thiamin has been added.

Sources of Thiamin

Signs/Symptoms of Thiamin Deficiency

Thiamin, or vitamin B1, deficiency is rare now that many foods come enriched with vitamins.

Symptoms can include fatigue, irritability, sleep disturbances and abdominal discomfort.

People more at risk are individuals who abuse alcohol, and those with heart failure, gastrointestinal diseases, or eating disorders, as well as the elderly.

Deficiency of Thiamin can cause Beriberi (means I can’t, I can’t).

Causes weakness and impairs the nervous, muscle, gastrointestinal, and cardiovascular systems.

Symptoms include peripheral neuropathy and weakness, muscle pain and tenderness, enlargement of the heart, difficulty breathing, edma, anorexia, weight loss, poor memory, and confusion

Signs/Symptoms of Thiamin Deficiency

Continued…Dry Beriberi

The main symptoms are related to the nervous and muscular systems

Wet Beriberi In addition the

neurological symptoms, the cardiovascular system is affected.

Heart is enlarged, breathing may be difficult, and congestive heart failure may occur.

Toxic Effects Of Thiamin Deficiency

In severe thiamin deficiency, brain damage can occur. One type is called Korsakoff syndrome. The other is Wernicke's disease. Either or both of these conditions can occur in the same person.

Symptoms include changes in vision, ataxia, confusion, and apathy.

There is no known poisoning linked to thiamin.

Toxic effects

Thiamin is generally considered safe and nontoxic, even at high doses. Doses higher than 100 mg may cause drowsiness or muscle relaxation, and some people report a burning sensation when thiamin is received via injection.

Recommended daily intake

Females Age group 19

and older-1.1 mg/day.

Males Age group 19

and older- 1.2 mg/day.

Reliable Resources

http://health.cvs.com/GetContent.aspx?token=f75979d3-9c7c-4b16-af56-3e122a3f19e3&chunkiid=26273

http://www.livestrong.com/article/408468-signs-symptoms-of-thiamine-deficiency/

Wardlaws’s Perspective in Nutrition 10th Edition