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Page 1: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

Sheraton Gunter Hotel

Program (update 12/1)

Page 2: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

December 4, 2011

Tutorial Session

Chair: Dr. Jianhua Ruan, University of Texas at San AntonioRoom: Alamo

1. Systems Biology in Epigenetic Regulation

Presenter: Dr. Yunlong Liu, Assistant professor, Department of Medical and Molecular Genetics, Indiana University School of MedicineDr. Kun Huang, Associate professor, Department of Biomedical Informatics, the Ohio State UniversityTime: 1:00 pm to 3:00 pm

3:00 pm to 3:30 pm Break

2. Ion Torrent – Open, Accessible, and Enabling

Presenter: Matt Dyer, Ph.D. Ion Torrent, Sr. Product Manager, Bioinformatics & CommunityTime: 3:30 pm to 5:30 pm

6:00 pm to 8:00 pm Reception at Biga on the Banks

Page 3: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

December 5, 2011

Plenary Talks Room: Alamo

7:50 am Opening remark

8:00 am to 8:45 amPlenary talk 1

Chair: Dr. Yidong Chen

Personalizing Cancer Medicine: Bioinformatics and the Omic Revolution

Dr. John N. WeinsteinProfessor and Chair, Department of Bioinformatics and Computational Biology, Division of

Quantitative Sciences, The University of Texas MD Anderson Cancer Center

8:45 am to 9:30 am Plenary talk 2

Chair: Dr. Fuli Yu

Unstable DNA and Human Disease: Fragile X syndrome and FXTAS

Dr. David NelsonProfessor, Department of Molecular and Human Genetics, Baylor College of Medicine

9:30 am to 9:50 am Break & posters

9:50 am to 10:35 am Plenary talk 3

Chair: Dr. Kun Huang

Integrative Analyses of Methylome, Cistrome, and Chromatin InteractomeDr. Tim Huang

Professor and Chair, Department of Molecular MedicineDeputy Director, CTRC

University of Texas Health Science Center at San Antonio

Page 4: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

Main Sessions

Session: 1 Next Generation Sequencing for Epigenetic Research

Chairs: Dr. Yunlong Liu, Assistant professor, Department of Medical and Molecular Genetics, Indiana University School of MedicineDr. Kun Huang, Associate professor, Department of Biomedical Informatics, the Ohio State UniversityTime: 10:40 am to 12:00 amRoom: Alamo

1. A Scalable, Flexible Workflow for MethylCap-Seq Data Analysis Benjamin Rodriguez1, Hok-Hei Tam1, David Frankhouser1, Michael Trimarchi1, Mark Murphy1,Chris Kuo1, Deval Parikh1, Bryan Ball1, Sebastian Schwind1, John Curfman1, William Blum1, Guido Marcucci1, Pearlly Yan1,Ralf Bundschuh2

1. The Ohio State University Comprehensive Cancer Center Columbus, Ohio, USA, 2. Departments of Physics and Biochemistry, Center for RNA Biology, The Ohio State University Columbus, Ohio, USA.

2. An ERα/Modulator Regulatory Network in the Breast Cancer CellsHeng-Yi Wu1, Yu Wang1, P. Zheng1, G. Jiang1,Yunlong Liu1,Kenneth P. Nephew2,Tim H. M. Huang3, Lang Li4

1.Center for Computational Biology and Bioinformatics Indiana University Indianapolis, Indiana USA2.Medical Sciences, School of Medicine Indiana University Bloomington, Indiana USA3.Department of Molecular Virology, Immunology, and Medical Genetics The Ohio State University Columbus, Ohio USA4.Department of Medical and Molecular Genetics Indiana University Indianapolis, Indiana USA.

3. Empirical Bayes Model Comparisons for Differential Methylation AnalysisMingxiang Teng1, Yadong Wang1,Curt Balch2, Kenneth P. Nephew2, Yunlong Liu3, Lang Li4, Seongho Kim5

1.School of Computer Science and Technology Harbin Institute of Technology Harbin, Heilongjiang, China2.Medical Sciences Indiana University Bloomington, Indiana, USA3.Department of Medicine, Indiana University Indianapolis, Indiana, USA4.Department of Medical and Molecu-lar Genetic, Indiana University Indianapolis, Indiana, USA5.Department of Bioinformatics and Biostatistics University of Louisville, Louisville, Kentucky, USA.

4. Chromatin signature analysis and prediction of genome-wide novel promoters using finite mixture modelCenny Taslim1, Shili Lin1, Kun Huang2, Tim Huang3

1.Department of StatisticsColumbus, OH 43210, USA.2.Department of Biomedical Informatics, Columbus, OH 43210, USA.3.Department of Molecular Virology, Immunology and Medical GeneticsColumbus, OH 43210, USA.

Page 5: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

Session: 2 Gene Regulation Network I

Chair: Dr. Erchin Serpedin, Texas A&M UniversityTime: 9:50 am to 11:50 amRoom: Baker

1. Uncertainty-based Essentiality in Gene Regulatory NetworksXiaoning Qian1, Byung-Jun Yoon2and Edward R. Dougherty2,3,4,1. Dept. of Computer Science & Engineering, University of South Florida, Tampa, FL 33620 2. Dept. of Electrical & Computer Engineering, Texas A&M University, College Station, TX 778433. Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ 850044.Dept. of Bioinformatics and Computational Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030

2. The effect of certain Boolean functions in stability of networks with varying topologyVitor H. P. Louzada1, Ronaldo F. Hashimoto1,Fabr´ıcio M. Lopesy2. 1.Institute of Mathematics and Statistics of the University of S˜ao Paulo, Brazil2.Federal University of Technology - Paran´a, Brazil

3. A Cubature Kalman Filter Approach for Inferring Gene Regulatory Networks Using Time Series DataAmina Noor1, Erchin Serpedin1, Mohamed Nounou2and Hazem Nounou2

1.Department of Electrical and Computer EngineeringTexas A&M University, College Station, Texas 77843.2. Texas A&M University at Qatar, Doha, Qatar 23874.

4. A novel critical time analysis approach for Genetic Regulatory NetworksSonal Bhattacharya, Ranadip PalElectrical and Computer Engineeirng Department, Texas Tech University, Lubbock, TX, USA

1:20 pm to 2:00 pm

Round Table with funding agencies

Dr. Ray Jacobson

Scientific Review OfficerBioengineering Sciences and Technologies

Center for Scientific ReviewNational Institutes of Health

Page 6: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

Room: Alamo

Session: 3 Computational Methods for Therapeutic

Chair: Dr. Ronaldo F. Hashimoto, University of Sao PauloTime 2:00 pm to 4:00 pmRoom: Alamo

1. Efficient Combinatorial Drug Optimization Through Stochastic SearchMansuck Kim, Byung-Jun Yoon Department of Electrical and Computer Engineering Texas A&M University.

2. A novel approach for tumor sensitivity prediction and combination therapy design for targeted drugsNoah Berlow,Ranadip Pal.Texas Tech UniversityLubbock, TX, 79409, USA.

3. Modeling Cyclic and Acyclic Therapeutic Methods with Persistent Intervention Effect in Probabilistic Boolean NetworksMohammadmahdi R. Yousefi1, Aniruddha Datta1, Edward R. Dougherty1,2,3

1.Dept. of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA.2.Comp. Biology Division, Translational Genomics Research Institute, Phoenix, AZ, USA.3.Dept. of Bioinf. and Comp. Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.

4. Predicting Drug Efficacy Based on the Integrated Breast Cancer Pathway Model Hui Huang1, Xiaogang Wu1, Sara Ibrahim2 , Marianne McKenzie3, Jake Y. Chen4

1.School of Informatics, Indiana University.2. School of Medicine Indiana University.3. School of Science Purdue University. 4. School of Informatics Indiana University.

Page 7: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

5. Identifying Genes Associated with Chemotherapy Response in Ovarian Carcinomas Based on DNA Copy Number and Expression ProfilesFang-Han Hsu1, Erchin Serpedin1, Tzu-Hung Hsiao3, Alexander J.R. Bishop3,4,Edward R. Dougherty1,2,Yidong Chen3,5

1.Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX.2.Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ.3.Greehey Children’s Cancer Research Institute.4.Department of Cellular and Structural Biology.5.Department of Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, San Antonio, TX.

6. Assessing the Efficacy of Molecularly Targeted Agents by Using Kalman Filter Xiangfang (Lindsey) Li, Lijun Qian, Michael L. Bittner, and Edward R. Dougherty

Session: 4 Gene Regulation Network II

Chair: Dr. Nevenka Dimitrova, Philips ResearchTime 2:00 pm to 4:00 pmRoom: Baker

1. Probabilistic consistency transformation for multiple alignment of biological networksSayed Mohammad Ebrahim Sahraeian, Byung-Jun YoonDepartment of Electrical & Computer EngineeringTexas A&M University, College Station, TX 77843-3128, USA.

2. Attractor Estimation and Model Refinement for Stochastic Regulatory Network ModelsJason Knight1, Edward Dougherty1, 2

1. Dept. of Electrical and Computer Engineering, Texas A&M University College Station, Texas 77843 USA 2. Computational Biology Division, Translational Genomics Research Institute,Phoenix, Arizona 85004 USA.

3. Steady state probability approximation applied to stochastic model of biological networkMd. Shahriar Karim, David M. Umulis and Gregery T. Buzzard.

Page 8: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

4. Identification of biomarkers in breast cancer metastasis by integrating protein-protein interaction network and gene expression dataMd Jamiul Jahid, Jianhua RuanDepartment of Computer Science The University of Texas at San AntonioSan Antonio, USA

5. Pathway Analysis in the Context of Bayesian Networks - Mathematical Modeling of Master and Canalizing GenesChen Zhao1,2, Ivan Ivanov3, Michael L. Bittner2, Edward R.Dougherty1, 2, 4

1.Dept. of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA.2.Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ, USA.3.Dept. of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX, USA.4.Dept. of Bioinformatics and Computational Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX, USA.

6. Gene Network Inference via Sparse Structural Equation Modeling with Genetic PerturbationsXiaodong Cai1, Juan Andr´es Bazerque2, Georgios B. Giannakis2.

1.Dept. of ECE, Univ. of MiamiCoral Gables, FL 33146, USA.2.Dept. of ECE, Univ. of Minnesota, Minneapolis, MN 55455, USA.

4:00 pm to 4:20 pm Break & posters

Session: 5 Data Integration

Chair: Dr. Xiaoning Qian, University of South FloridaTime 4:20 pm to 6:20 pmRoom: Alamo

1. Improvement of GNs inference through biological data integrationF´abio Fernandes da Rocha Vicente1;2, Fabr´ıcio M. Lopes1, Ronaldo F. Hashimoto2

1. Federal University of Technology - Paran´a, Brazil2. Institute of Mathematics and Statistics, University of S˜ao Paulo, Brazil

2. Multisource Biological Pathway Consolidation

Page 9: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

Mark S. Doderer1, Zachry Anguiano1, Uthra Suresh1, Ravi Dashnamoorthy1, Alexander J.R. Bishop1, 2, 4, and Yidong Chen1, 3, 4

1.Greehey Children’s Cancer Research Institute. 2.Department of Cellular and Structural Biology.3. Department of Epidemiology and Biostatistics, and 4.Cancer Therapy & Research Center, The University of Texas Health Science Center at San Antonio San Antonio, USA.

3. A Method For Finding Novel Associations Between Genome-Wide Copy Number And DNA Methylation PatternsMan-Hung Eric Tang1, Vinay Varadan2, Sid Kamalakaran2, Michael Q. Zhang3 ,Nevenka Dimitrova2, James Hicks1

1. Cold Spring Harbor Laboratory, 1 Bungtown Rd, NY 12724, USA 2. Philips Research North America, 345 Scarborough Rd, Briarcliff Manor, NY 10510, USA 3. The University of Texas at Dallas, Richardson TX 75080, USA and Tsinghua University, Beijing, 100084 China.

4. Stochastic Modeling of Dynamic Effects of Copy Number Alterations upon Gene Expression LevelsFang-Han Hsu1, Erchin Serpedin1, Yidong Chen2,3, and Edward R. Dougherty1, 4

1. Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX.2. Department of Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, San Antonio, TX.3. Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX.4. Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ.

5. Efficient Cancer Therapy using Boolean Networks and Max-SAT-based ATPGPey-Chang Kent Lin, Sunil P. KhatriDepartment of ECE, Texas A&M University, College Station TX 77843

6. Designing Enhanced Classifiers Using Prior Process Knowledge: Regularized Maximum-LikelihoodMohammad Shahrokh Esfahani1, Amin Zollanvari2, Byung-Jun Yoon1, and Edward R. Dougherty1,3

1.Department of Electrical and Computer Engineering, Texas A&M University.2. Childrens Hospital Informatics Program at Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Brigham and Womens Hospital.3. Computational Biology Division, Translational Genomics Research Institute (TGen), Phoenix, Arizona, USA.

Session: 6 Proteomics data processing

Chairs:

Page 10: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

Dr. Ulisses Braga-Neto, Texas A&M UniversityDr. Jianqiu (Michelle) Zhang, University of Texas at San AntonioTime 4:20 pm to 6:20 pmRoom: Baker

1. Finding Effective Subnetwork Markers for Cancer by Passing MessagesByung-Jun YoonDepartment of Electrical and Computer Engineering Texas A&M University, College Station, TX.

2. Application of Survival Analysis Methodology to the Quantitative Analysis of LC-MS Proteomics DataCarmen D. Tekwe, Alan R. Dabney, Raymond J. CarrollDepartment of Statistics Texas A & M University College Station, TX 77843-3143

3. Mapping of International Protein Index to Affymetrix Probe-Set Identifier for Correlating Genomics and Proteomics Expression Profiles in Multiple MyelomaShweta S. Chavan 1,2, John D. Shaughnessy Jr.1, Bart Barlogie1, Ricky D. Edmondson1

1.Myeloma Institute for Research and Therapy, University of Arkansas Medical Sciences (UAMS), 4301 W. Markham Street, Slot#776, Little Rock, AR 72205, USA.2. University of Arkansas Little Rock–UAMS Joint Bioinformatics Program, 2801 S. University Avenue, Little Rock, AR 72204, USA.

4. Multiple Reaction Monitoring: Modeling and Systematic AnalysisEsmaeil Atashpaz-Gargari1, Ulisses M. Braga-Neto1, and Edward R. Dougherty1;2;3

1. Dept. of Electrical and Computer Engineering, Texas A&M University.2. Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ.3. Dept. of Bioinformatics and Computational Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX.

5. Joint Corresponding Feature Identification and Alignment for Multiple LC/MS ReplicatesJian Cui, Xuepo Ma, Jianqiu(Michelle) ZhangDepartment of Electrical and Computer Engineering University of Texas at san Antonio San Antonio, Texas 78249.

6. Modeling and systematic analysis of LC-MS proteomics pipelineYouting Sun1, Ulisses Braga-Neto1, Edward R. Dougherty1;2;3

1. Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX.2. Computational Biology Division, Translational Genomics Research Institution, Phoenix, AZ.3. Department of Bioinformatics and Computational Biology, University of Texas M.D. Anderson Cancer Center, Houston, TX

Page 11: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

Session: 7 Next Generation Sequencing Data analysis and Application

Chair: Dr. Yidong Chen, University of Texas Health Science Center at San AntonioTime 4:20 pm to 6:00 pmRoom: Mahncke

1. Enabling Atlas2 Personal Genome Analysis on the Cloud Uday S. Evani1,4, Danny Challis1, Jin Yu1, Andrew R. Jackson2,3, Sameer Paithankar2,3, Matthew N. Bainbridge1, Cristian Coar-fa2,3, Aleksandar Milosavljevic2,3,4, Fuli Yu1,3,4

1. The Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. 2.Bioinformatics Research Laboratory, Epigenome Center, Department of Molecular and Human Genetics. 3. Department of Molecular and Human Genetics, Baylor College of Medicine, TX 77030, USA. 4. Corresponding authors.

2. A Sequential Monte Carlo Base-calling Method for next-generation DNA SequencingXiaohuShen and HarisVikaloDepartment of Electrical and Computer Engineering, University of Texas at Austin

3. Comparative Copy Number Variation from Whole Genome SequencingAngel Janevski, VinayVaradan, SitharthanKamalakaran, Nilanjana Banerjee, Nevenka DimitrovaPhilips Research, 345 Scarborough Rd, Briarcliff Manor, NY 10510.

4. Beyond Seed Match: Improving miRNA Target Prediction using PAR-CLIP DataMingzhu Lu1, C. L. Philip Chen2, Yufie Huang1

1. Department of Electrical and Computer Engineering, The University of Texas at San Antonio, TX, USA.2. Faculty of Science of Technology, University of Macau, China.

5. Put your NGS data to work: Creating Biological Contextualization with Agilent’s Next-Gen Sequencing Analysis SoftwareDipanwita Roy Choudhury

Agilent

Page 12: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

7:00 pm to 9:00 pm Banquet at Mi Tierra

December 6, 2011

Plenary Talks Room: Alamo

8:00 am to 8:45 am

Plenary talk 4Chair: Dr. Fuli Yu

Selectionism vs. neutralism in the evolution of cells of hepatocelluar carcinoma

Dr. Chung-I Wu

Professor and Director, Beijing Institute of Genomics, Chinese Academy of Science. Department of Ecology and Evolution

University of Chicago

8:45 am to 9:30 am

Plenary talk 5Chair: Dr. Yufei Huang

Systems Pharmacology Strategies for Faster-to-Market Drug Development

Dr. Stephen WongSenior Member, The Methodist Hospital Research Institute, Department Chair, John S

Dunn, Distinguished Endowed Chair in Biomedical Engineering, Department of Systems Medicine and Bioengineering , Associate Director of Translational Research,

Methodist Cancer Center, Professor of Radiology, Professor of Neuroscience, Professor of Pathology and Laboratory Medicine,Weill Cornell Medical College of Cornell

University9:30 am to 9:50 am Break & posters

Page 13: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

Main Sessions

Session: 8 Clustering and Classification Methods

Chair: Dr. Ranadip Pal, Texas Tech UniversityTime 9:50 am to 11:50 amRoom: Alamo

1. Classifier Error Estimator Performance in a Bayesian ContextLori Dalton1, Edward R. Dougherty1, 2, 3

1.Dept. of Electrical and Computer Engineering, Texas A&M University, College Station, TX USA.2.Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ USA.3.Dept. of Bioinf. and Computational Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX USA.

2. Sample-Based Estimators for the Intrinsically Multivariate Prediction ScoreTing Chen, Ulisses Braga-NetoDepartment of Electrical Engineering Texas A & M University College Station, Texas 77843

3. Clustering Gene Expression Data using Probabilistic Non-negative Matrix FactorizationBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3

1.Department of Electrical Engineering Ecole Nationale d’Ing´enieurs de Tunis, Tunisia. 2. Department of Systems Engineering University of Arkansas at Little Rock, USA. 3. Department of Mathematics University of Alabamaat Birmingham, USA.

4. Relationship between the accuracy of classifier error estimation and distribution complexityEsmaeil Atashpaz-Gargari1, Chao Sima2, Ulisses M. Braga-Neto1, and Edward R. Dougherty1, 2, 3

1. Dept. of Electrical and Computer Engineering, Texas A&M University.2.Computational Biology Division, Translational Genomics Research Institute, Phoenix, AZ.3.Dept. of Bioinformatics and Computational Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX.

5. Geometrical Modification Of Wavelet SVM Kernels And Its Application In Microarray AnalysisHong Cai , Yufeng WangDepartment of BiologyUniversity of Texas at San Antonio, San Antonio, TX 78249, USA.

Page 14: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

6. S-score : a Novel Scoring Method of Gene Signatures for Molecular ClassificationHung-I Harry Chen1, Tzu-Hung Hsiao1, Yidong Chen1, 2, Charles Keller3

1.Greehey Children’s Cancer Research Institute 2.Department of Epidemiology and Biostatistics,University of Texas Health Science Center at San Antonio, San Antonio, Texas3. Pediatric Cancer Biology Program, Pap Papé Family Pediatric Research Institute Family Pediatric Research Institute,Department of Pediatrics, Oregon Health and Science University, Portland, Oregon.

Session: 9 MicroRNA, Gene Networks, Next-Generation Sequencing Methods

Chair: Dr. Byung-Jun Yoon , Texas A&M UniversityTime 9:50 am to 11:50 amRoom: Baker

1. Computational Prediction of microRNA Regulatory PathwaysDong Yue1, Yidong Chen2, Shou-Jiang Gao3, Yufei Huang1

1.Department of Electrical and Computer Engineering, University of Texas at San Antonio, U.S.2.Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, U.S.3. Departments of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, U.S.

2. Inference of a Genetic Regulatory Network model from limited time series dataSaadHaider,Ranadip Pal Texas Tech University, Lubbock, TX, 79409, USA.

3. Modelling Oxidative Stress Response PathwaysSriram Sridharan1, Ritwik Layek1, Aniruddha Datta1, Jijayanagaram Venkatraj2

1. Texas A & M University, Electrical and Computer Engineering, College Station, TX, 77843-3128, USA.2. Texas A & M University, Vet Integrative Biosciences, College Station, TX, 77843-4458, USA.

4. Clustering DNA methylation expressions using nonparametric beta mixture modelLin Zhang1, Jia Meng2, Hui Liu1, Yufei Huang1

1.School of Information and Electrical Engineering, China University of Mining and Technology2. Department of Electrical and Computer Engineering, University of Texas at San Antonio, U.S.

Page 15: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

5. A Novel Approach for Alignments Output Storage Problem Facing Clinical ScenariosYiqi Lu1,Yaoliang Chen2, Fuli Yu3,Yanghua Xiao4,Danfeng Xu5

1. School of Computer Science, Fudan University Shanghai 200433, PR China.2. School of Computer Science, Fudan University Shanghai 200433, PR China. 3. The Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030 USA.4. School of Computer Science, Fudan University Shanghai 200433, PR China. (Corresponding Author)5. School of Computer Science, Fudan University Shanghai 200433, PR China.

6. Personal Genome Privacy Protection with Feature-based Hierarchical Dual-stage EncryptionsXukai Zou1, Peng Liu2, Jake Y. Chen3

1. Department of Computer & Information Science,Purdue University Indianapolis, IN 46202, USA. 2. College of Information Science and Technology Penn State University, University Park, PA 16802, USA.3. School of Informatics Indiana University Indianapolis, IN 46202, USA.

Session: 10 ISIMB 2011

Chairs: Dr. Yufang Jin, Universityof Texas at San AntoniTime 9:50 am to 11:50 amRoom: Mahncke

1. ECF sigma factor-associated regulatory networks in Streptomyces colicolor A3(2)Zhan Zhou1, 2, Qi Li1, Julie Tudyk1, Yong-Quan Li2 and Yufeng Wang1, 3

1. Department of Biology, University of Texas at San Antonio, San Antonio, TX 78249, USA.2. College of Life Sciences, Zhejiang University, Hangzhou 310058, P. R. China.3. South Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, San Antonio, TX 78249, USA.

2. Transcriptomic analysis using svd clustering and svm classificationHong Cai , Yufeng WangDepartment of BiologyUniversity of Texas at San Antonio, San Antonio, TX 78249, USA

3. A Compton scattering suppression based Image reconstruction method for digital brest tomosynthesisShiyu Xu1 and Ying Chen1,2

1. Department of Electrical and Computer Engineering, Southern Illinois University, Carbondale, IL 62901.2. Biomedical Engineering Graduate Program,Southern Illinois University.

Page 16: compgenomics.utsa.educompgenomics.utsa.edu/.../gensips11_program_rev113011.docx · Web viewBelhassen Bayar1, Nidhal Bouaynaya2, Roman Shterenberg3 1.Department of Electrical Engineering

4. Effects of slice thickness filter in filtered backprojection reconstruction with parallel breast tomosynthesis imaging configurationLinlin Cong1, Weihua Zhou2, Ying Chen1,2

1. Biomedical Engineering Graduate Program,Southern Illinois University.2. Department of Electrical and Computer Engineering, Southern Illinois University, Carbondale, IL 62901.

5. Targeting myocardial infarction-specific protein interactions using computational analysesNguyen Nguyen1, Xiaolin Zhang1,Yunji Wang1, Hai-Chao Han1, Yufang Jin1, Galen Schmidt2, Richard A. Lange3, Robert J. Chilton3, Merry Lindsey3

1. Dept. of ECE University of Texas at San Antonio San Antonio, TX 78249, USA.2. Dept. of ECE Rice University Houston, TX 77005, USA.3. Dept. of Medicine University of Texas Health Science Center at San Antonio San Antonio, TX 78229, USA.

6. Mathematical modeling of macrophage activation in left ventricular remodeling post-myocardial infarctionYunji Wang1, Yufang Jin1, Yonggang Ma2, Ganesh V Halade2, Merry L. Linsey2

1.Department of Electrical and Computer Engineering, University of Texas at San Antonio San Antonio, Texas 78249, USA.2. Department of Medicine-Cardiology University of Texas Health Science Center at San Antonio San Antonio, TX 78229, USA

1:30 pm to 5:30 pm

UTSA Downtown CampusBuena Vista St. Bldg 3.328

Hands-on workshop on next Gen-sequencing Data Analysis

By Texas Advanced Computing Center