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Bilaga 4: Publikationer (original publikationer, reviews, skrifter i icke-refereegranskade tidskrifter) vid IMM per verksamhetsrområde 2000-2002 1 Verksamhetsområde Epidemiologi Originalpublikationer 1. Alfredsson L, Hammar N, Fransson E, de Faire U, Hallqvist J, Knutsson A, Nilsson T, Theorell T, Westerholm P. Job strain and major risk factors for coronary heart disease. Baseline results from the WOLF study. Scand J Work Environ Health 2002;28:238-48. 2. Forssén UM, Ahlbom A, Feychting M. The relative contribution of residential and occupational magnetic field exposure over 24 hours among people living close to and far from a power line. Bioelectromagnetics, 2002;23:239-244. 3. Frid C, Annerén G, Rasmussen F, Sundelin C, Drott P. Utilisation of medical care among children with Down’s syndrome. Journal of Intellectual Disability Research 2002; 46: 310-317. 4. Gunnell D, Harrison G, Rasmussen F, Fouskakis D, Tynelius P. Associations between pre-morbid intellectual performance, early-life exposures and early onset schizophrenia. Br J Psychiatr 2002;181:298-305. 5. Hammar N, Kaprio J, Hagström U, Alfredsson L, Koskenvuo M, Hammar T. Migration and mortality - a 20- year follow-up of Finnish twin pairs with migrant co-twins in Sweden. J Epidemiol Community Health 2002;56:362-6. 6. Hammar N, Linnersjö A, Alfredsson L, Dammström B-G, Johansson M, Eliasch H. Cancer incidence in airline and military pilots in Sweden 1961-1996. Aviat Space Environ Med 2002;73:2-7. 7. Isaksson B, Jonsson F, Pedersen NL, Larsson J, Feychting M, Permert J. Lifestyle factors and pancreatic cancer risk: A cohort study from the Swedish Twin Registry. Int J Cancer, 2002;98:480-482. 8. Jartti L, Raitakari OT, Kaprio J, Järvisalo MJ, Toikka JO, Marniemi J, Hammar N, Luotolahti M, Koskenvuo M, Rönnemaa T. Increased carotid intima-media thickness in men born in east Finland: a twin study of the effects of birth place and migration to Sweden on subclinical atherosclerosis. Ann Med 2002;34:162-70. 9. Jartti L, Rönnemaa T, Järvisalo MJ, Toikka JO, Marniemi J, Hammar N, Kaprio J, Koskenvuo M, Raitakari OT. Environmental and genetic effects on endothelial function and intima-media thickness – a study of co-twins in Finland and Sweden. Arteriosclerosis, Thrombosis and Vascular Biology. 2002;22:832-7. 10. Johansson-Kark M, Rasmussen F, Hjern A. Overweight among international adoptees in Sweden. A population- based study. Acta Paediatr 2002;91:827-832. 11. Johansen C, Feychting M, Møller M, Arnsbo P, Ahlbom A, Olsen JH. Risk for severe cardiac arrythmia in male utility workers: a nationwide cohort study. Am J Epidemiol 2002;156:857-861. 12. Johansson-Kark M, Rasmussen F, De Stavola B, Leon DA. Fetal growth and systolic blood pressure in young adulthood. The Swedish young male twins study. Paediatr Perinat Epidemiol 2002;16:200-209. 13. Magnusson P K E, Rasmussen F. Familial resemblance of body mass index and familial risk of high and low body mass index. A study of young men in Sweden. Int J Obes 2002; 26: 1225-1231. 14. Michaelsson K, Baron JA, Farahmand BY, Ljunghall S. Use of low potency estrogens does not reduce the risk of hip fracture. Bone 2002; 30:613-8. 15. Monge P, Wesseling C, Rodríguez AC, Cantor K, Weiderpass E, Reutfors J, Ahlbom A, Partanen T. Childhood leukemia in Costa Rica, 1981-1996. Paediatric Perinatal Epidemiol 2002 Jul;16(3): 210-18 16. Nilsson L, Ahlbom A, Farahmand BY, Asberg M, Tomson T. Risk Factors for Suicide in Epilepsy: A Case Control Study Epilepsia 2002; 43(6):644-651 17. Persson HB, Alberts KA, Farahmand BY, Tomson T. Risk of extremity fractures in adult outpatients with epilepsy. Epilepsia 2002; 43:768-72.

Verksamhetsområde Epidemiologi - Karolinska Institutet · Verksamhetsområde Epidemiologi Originalpublikationer 1. Alfredsson L, Hammar N, Fransson E, de Faire U, Hallqvist J, Knutsson

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Page 1: Verksamhetsområde Epidemiologi - Karolinska Institutet · Verksamhetsområde Epidemiologi Originalpublikationer 1. Alfredsson L, Hammar N, Fransson E, de Faire U, Hallqvist J, Knutsson

Bilaga 4: Publikationer (original publikationer, reviews, skrifter i icke-refereegranskade tidskrifter) vid IMM per verksamhetsrområde 2000-2002

1

Verksamhetsområde Epidemiologi Originalpublikationer 1. Alfredsson L, Hammar N, Fransson E, de Faire U, Hallqvist J, Knutsson A, Nilsson T, Theorell T, Westerholm P. Job strain and major risk factors for coronary heart disease. Baseline results from the WOLF study. Scand J Work Environ Health 2002;28:238-48. 2. Forssén UM, Ahlbom A, Feychting M. The relative contribution of residential and occupational magnetic field exposure over 24 hours among people living close to and far from a power line. Bioelectromagnetics, 2002;23:239-244. 3. Frid C, Annerén G, Rasmussen F, Sundelin C, Drott P. Utilisation of medical care among children with Down’s syndrome. Journal of Intellectual Disability Research 2002; 46: 310-317. 4. Gunnell D, Harrison G, Rasmussen F, Fouskakis D, Tynelius P. Associations between pre-morbid intellectual performance, early-life exposures and early onset schizophrenia. Br J Psychiatr 2002;181:298-305. 5. Hammar N, Kaprio J, Hagström U, Alfredsson L, Koskenvuo M, Hammar T. Migration and mortality - a 20-year follow-up of Finnish twin pairs with migrant co-twins in Sweden. J Epidemiol Community Health 2002;56:362-6. 6. Hammar N, Linnersjö A, Alfredsson L, Dammström B-G, Johansson M, Eliasch H. Cancer incidence in airline and military pilots in Sweden 1961-1996. Aviat Space Environ Med 2002;73:2-7. 7. Isaksson B, Jonsson F, Pedersen NL, Larsson J, Feychting M, Permert J. Lifestyle factors and pancreatic cancer risk: A cohort study from the Swedish Twin Registry. Int J Cancer, 2002;98:480-482. 8. Jartti L, Raitakari OT, Kaprio J, Järvisalo MJ, Toikka JO, Marniemi J, Hammar N, Luotolahti M, Koskenvuo M, Rönnemaa T. Increased carotid intima-media thickness in men born in east Finland: a twin study of the effects of birth place and migration to Sweden on subclinical atherosclerosis. Ann Med 2002;34:162-70. 9. Jartti L, Rönnemaa T, Järvisalo MJ, Toikka JO, Marniemi J, Hammar N, Kaprio J, Koskenvuo M, Raitakari OT. Environmental and genetic effects on endothelial function and intima-media thickness – a study of co-twins in Finland and Sweden. Arteriosclerosis, Thrombosis and Vascular Biology. 2002;22:832-7. 10. Johansson-Kark M, Rasmussen F, Hjern A. Overweight among international adoptees in Sweden. A population-based study. Acta Paediatr 2002;91:827-832. 11. Johansen C, Feychting M, Møller M, Arnsbo P, Ahlbom A, Olsen JH. Risk for severe cardiac arrythmia in male utility workers: a nationwide cohort study. Am J Epidemiol 2002;156:857-861. 12. Johansson-Kark M, Rasmussen F, De Stavola B, Leon DA. Fetal growth and systolic blood pressure in young adulthood. The Swedish young male twins study. Paediatr Perinat Epidemiol 2002;16:200-209. 13. Magnusson P K E, Rasmussen F. Familial resemblance of body mass index and familial risk of high and low body mass index. A study of young men in Sweden. Int J Obes 2002; 26: 1225-1231. 14. Michaelsson K, Baron JA, Farahmand BY, Ljunghall S. Use of low potency estrogens does not reduce the risk of hip fracture. Bone 2002; 30:613-8. 15. Monge P, Wesseling C, Rodríguez AC, Cantor K, Weiderpass E, Reutfors J, Ahlbom A, Partanen T. Childhood leukemia in Costa Rica, 1981-1996. Paediatric Perinatal Epidemiol 2002 Jul;16(3): 210-18 16. Nilsson L, Ahlbom A, Farahmand BY, Asberg M, Tomson T. Risk Factors for Suicide in Epilepsy: A Case Control Study Epilepsia 2002; 43(6):644-651 17. Persson HB, Alberts KA, Farahmand BY, Tomson T. Risk of extremity fractures in adult outpatients with epilepsy. Epilepsia 2002; 43:768-72.

Page 2: Verksamhetsområde Epidemiologi - Karolinska Institutet · Verksamhetsområde Epidemiologi Originalpublikationer 1. Alfredsson L, Hammar N, Fransson E, de Faire U, Hallqvist J, Knutsson

Bilaga 4: Publikationer (original publikationer, reviews, skrifter i icke-refereegranskade tidskrifter) vid IMM per verksamhetsrområde 2000-2002

2

18. Pukkala E, Aspholm R, Auvinen A, Eliasch H, Gundestrup M, Haldorsen T, Hammar N, Hrafnkelsson J, Kyyrönen P, Linnersjö A, Rafnsson V, Storm H, Tveten U. Incidence of cancer among Nordic airline pilots over five decades: occupational cohort study. BMJ 2002;325:567-71. 19. Rasmussen F, Johansson M. The swedish young male twins register: A resource for studying risk factors for cardiovascular disease and insulin resistance. Twin Research 2002;5:1-3. 20. Reutfors J, Kramárová E, Weiderpass E, Monge P, Wesseling C, Ahlbom A. Central nervous system tumours in children in Costa Rica, 1981-96. Paediatric and Perinatal Epidemiology 2002;16:219-225. 21. Rosendahl KI, Galanti MR, Gilljam H, Bremberg S, Ahlbom A. School and class environments are differently linked to future smoking among preadolescents. Prev Med. 2002; 34(6):649-54. 22. Söderberg KC, Naumburg E, Anger G, Cnattingius S, Ekbom A, Feychting M. Childhood leukemia and magnetic fields in infant incubators. Epidemiology 2002;13:45-9. 23. Wesseling C, Keifer M, Ahlbom A, McConnell R, Moon JD, Rosenstock L, Hogstedt C. Long-term neurobehavioral effects of mild poisonings with organophosphate and n-methyl carbamate pesticides among banana workers. Int J Occup Environ Health. 2002;8(1):27-34. 24. Alfvén T, Järup L, Elinder CG: Cadmium and lead in blood in relation to low bone mineral density and tubular proteinuri. Eviron Health Perspect 2002;110:699-702. 25. Alm JS, Sanjeevi CB, Miller EN, Dabadghao P, Lilja G, Pershagen G, Blackwell JM, Scheynius A: Atopy in children in relation to BCG vaccination and genetic polymorphisms at SLC11A1 (formerly NRAMP1) and D2S1471. Genes Immun 2002;3:71-7. 26. Alm JS, Swartz J, Björkstén B, Engstrand L, Engström J, Kuhn I, Lilja G, Möllby R, Norin E, Pershagen G, Reinders C, Wreiber K, Scheyniuis A: An anthroposophic lifestyle and intestinal microflora in infancy. Pediatr Allergy Immunol 2002;13:402-11. 27. Boffetta P, Nyberg F, Mukeria A, Benhamou S, Constantinescu V, Batura-Gabryel H, Bruske-Hohlfeld I, Schmid G, Simonato L, Pelkonen P, Hall J: O6-Alkylguanine-DNA-alkyltransferase activity in peripheral leukocytes, smoking and risk of lung cancer. Cancer Lett 2002;180:33-9. 28. Brauer M, Hoek G, Van Vliet P, Meliefste K, Fischer PH, Wijga A, Koopman LP, Neijens HJ, Gerritsen J, Kerhof M, Heinrich J, Bellander T, Brunekreef B: Air pollution from traffic and the development of respiratory infections and asthmatic and allergic symptoms in children. Am J Respir Crit Care Med 2002;166:1092-8. 29. Böhme M, Lannerö E, Wickman M, Nordvall SL, Wahlgren CF: Atopic dermatitis and concomitant disease patterns in children up to two years of age. Acta Derm Venereol 2002;82:98-103. 30. Floderus B, Stenlund C, Carlgren F: Occupational exposures to high frequency electromagnetic fields in the intermediate range. Bioelectromagnetics 2002;23:568-77. 31. Gegring U, Cyrys J, Sedlmeir G, Brunekreef B, Bellander T, Fischer P, Bauer CP, Reinhardt D, Wichmann HE, Heinrich J: Traffic-related air pollution and respiratory health during the first 2 years of life. Eur Respir J 2002;19:960-8. 32. Gustavsson P, Nyberg F, Pershagen G, Scheele P, Jaobsson R, Plato N: Low dose exposure to asbestos and lung cancer: dose-response relations and interaction with smoking in a population-based case-referent study in Stockholm, Sweden. Am J Epidemiol 2002;155:1016-22. 33. Hillert L, Berglind N, Arnetz BB, Bellander T: Prevalence of self-reported hypersensitivity to electric or magnetic fields in a population-based questionnaire survey. Scand J Work Environ Health 2002;28:33-41. 34. Hou SM, Fält S, Angelini S, Yang K, Nyberg F, Lambert B, Hemminki K: The XPD variant alleles are associated with increased aromatic DNA adduct level and lung cancer risk. Carcinogenesis 2002;23:699-603. 35. Håkansson N, Floderus B, Gustavsson P, Johansen C, Olsen JH: Cancer incidence and magnetic field exposure in industries using resistance welding in Sweden. Occup Environ Med 2002;59:481-6.

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Bilaga 4: Publikationer (original publikationer, reviews, skrifter i icke-refereegranskade tidskrifter) vid IMM per verksamhetsrområde 2000-2002

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36. Kihlström A. Lilja G, Pershagen G, Hedlin G: Exposure to birch pollen in infancy and development of atopic disease in childhood. J Allergy Clin Immunol 2002;110:78-84. 37. Kull I, Wickman M, Lilja G, Nordvall SL, Pershagen G: Breast feeding and allergic diseases in infants-a prospective birth cohort study. Arch Dis Child 2002;87:478-81. 38. Kwon HJ, Cho SH, Chung Y, Lagarde F, Pershagen G: Effects of the Asian dust events on daily mortality in Seoul, Korea. Environ Res 2002;90:1-5. 39. Lannerö E, Kull I, Tollin L, Pershagen G, Wickman M, Nordvall SL: Environmental risk factors for allergy and socioeconomic status in a birth cohort (BAMSE). Pediatr Allergy Immunol. 2002;13:182-7. 40. Lagarde F, Falk R, Almrén K, Nyberg F, Svensson H, Pershagen G: Glass-based radon-exposure assessment and lung cancer risk. J Expo Anal Environ Epidemiol 2002;12:344-4. 41. Lichtenstein P, deFaire U, Floderus B, Svartengren M, Svedberg P, Pedersen NL: The Swedish Twin Registry: a unique resource for clinical, epidemiological and genetic studies. J Intern Med 2002;252:184-205. 42. Lewis S, Brennan P, Nyberg F, Aahrens W, Constantinescu V, Mukeria A, Benhamou S, Batura-Gabryel H, Bruske-Hohlfeld I, Simonato L, Menezes A, Boffetta P: Cruciferous vegetable intake, GSTM1 genotype and lung cancer risk in a non-smoking population. IARC Sci Publ 2002;156:507-8. 43. Moradi T, Adami HO, Ekbom A, Wedren S, Terry P, Floderus B, Lichtenstein P: Physical activity and risk for breast cancer a prospective cohort study among Swedish twins. Int J Cancer 2002;100:76-81. 44. Navas-Acient A, Pollan M, Gustavsson P, Floderus B, Plato N, Dosemeci M: Interactive effect of chemical substances and occupational electromagnetic field exposure on the risk of gliomas and meningiomas in Swedish men. Cancer Epidemiol Biomakers Prev 2002;11:1678-83. 45. Thunqvist P, Lilja G, Wickman M, Pershagen G: Asthma in children exposed to nitrogen dioxide in ice arenas. Eur Respir J 2002;20:646-50. 46. Petrauskaite R, Pershagen G, Gurevicius R: Lung cancer near an industrial site in Lithuania with major emissions of airway irritants. Int J Cancer 2002;99:106-11. 47. Swerdlow AJ, deStavola BL, Floderus B, Holm NV, Kaaprio J, Verkasalo PK, Mack T: Risk factors for breast cancer at young ages in twin: an international population-based study. J Natl Cancer Inst 2002;21:1238-46. 48. Wickman M: Indirect exposure to cats at school and worsening of asthma in children. Monaldi Arch Chest Dis 2002;57:113-4. 49. Jensen-Urstad K, Svenungsson E, de Faire U, Silveira A, Witztum JL, Hamsten A, Frostegård J. Cardiac valvular abnormalities are frequent in systemic lupus erythematosus patients with manifest arterial disease. Lupus 2002;11:744-52. 50. Bennet AM, Brismar K, Hallqvist J, Reuterwall C, De Faire U. The risk of myocardial infarction is enhanced by a synergistic interaction between serum insulin and smoking. Eur J Endocrinol 2002;147:641-7. 51. Yasar U, Lundgren S, Eliasson E, Bennet A, Wiman B, de Faire U, Rane A. Linkage between the CYP2C8 and CYP2C9 genetic polymorphisms. Biochem Biophys Res Commun 2002;299:25-8. 52. Leander K, Wiman B, Hallqvist J, Falk G, de Faire U. The G-455 A polymorphism of the fibrinogen Bbeta-gene relates to plasma fibrinogen in male cases, but does not interact with environmental factors in causing myocardial infarction in either men or women. J Intern Med 2002;252:332-41. 53. Zdravkovic S, Wienke A, Pedersen NL, Marenberg ME, Yashin AI, de Faire U. Heritability of death from coronary heart disease: a 36-year follow-up of 20,966 Swedish twins. J Intern Med 2002;252:247-54.

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Bilaga 4: Publikationer (original publikationer, reviews, skrifter i icke-refereegranskade tidskrifter) vid IMM per verksamhetsrområde 2000-2002

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54. Kjeldsen SE, Dahlöf B, Devereux RB, Julius S, Aurup P, Edelman J, Beevers G, de Faire U, Fyhrquist F, Ibsen H, Kristianson K, Lederballe-Pedersen O, Lindholm LH, Nieminen MS, Omvik P, Oparil S, Snapinn S, Wedel H. Effects of losartan on cardiovascular morbidity and mortality in patients with isolated systolic hypertension and left ventricular hypertrophy: a Losartan Intervention for Endpoint Reduction (LIFE) substudy. JAMA 2002;288:1491-8. 55. Björkegren J, Silveira A, Boquist S, Tang R, Karpe F, Bond MG, de Faire U, Hamsten A. Postprandial enrichment of remnant lipoproteins with apoC-I in healthy normolipidemic men with early asymptomatic atherosclerosis. Arterioscler Thromb Vasc Biol 2002;22:1470-4. 56. Alfredsson L, Hammar N, Fransson E, de Faire U, Hallqvist J, Knutsson A, Nilsson T, Theorell T, Westerholm P. Job strain and major risk factors for coronary heart disease among employed males and females in a Swedish study on work, lipids, and fibrinogen. Scand J Work Environ Health 2002;28:238-48. 57. Lindholm LH, Ibsen H, Borch-Johnsen K, Olsen MH, Wachtell K, Dahlöf B, Devereux RB, Beevers G, de Faire U, Fyhrquist F, Julius S, Kjeldsen SE, Kristianson K, Lederballe-Pedersen O, Nieminen MS, Omvik P, Oparil S, Wedel H, Aurup P, Edelman JM, Snapinn S. Risk of new-onset diabetes in the Losartan Intervention for Endpoint reduction in hypertension study. J Hypertens 2002;20:1879-86. 58. Pockley AG, de Faire U, Kiessling R, Lemne C, Thulin T, Frostegård J. Circulating heat shock protein and heat shock protein antibody levels in established hypertension. J Hypertens 2002;20:1815-20. 59. Iliadou A, Lichtenstein P, Morgenstern R, Forsberg L, Svensson R, de Faire U, Martin NG, Pedersen NL. Repeated blood pressure measurements in a sample of Swedish twins: Heritabilities and associations with polymorphisms in the renin-angiotensin-aldosterone system. J Hypertens 2002;20:1543-50. 60. Kjeldsen SE, Hedner T, Syvertsen JO, Lund-Johansen P, Hansson L, Lanke J, Lindholm LH, de Faire U, Dahlöf B, Karlberg BE. Influence of age, sex, and blood pressure on the principal endpoints of the Nordic Diltiazem (NORDIL) Study. J Hypertens 2002;20:1231-7. 61. Steuer J, Blomqvist P, Granath F, Rydh B, Ekbom A, de Faire U, Stahle E. Hospital readmission after coronary artery bypass grafting: are women doing worse? Ann Thorac Surg 2002;73:1380-6. 62. Lindholm LH, Ibsen H, Dahlöf B, Devereux RB, Beevers G, de Faire U, Fyhrquist F, Julius S, Kjeldsen SE, Kristianson K, Lederballe-Pedersen O, Nieminen MS, Omvik P, Oparil S, Wedel H, Aurup P, Edelman J, Snapinn S, for the LIFE study group. Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 2002;359:1004-10. 63. Dahlöf B, Devereux RB, Kjeldsen SE, Julius S, Beevers G, de Faire U, Fyhrquist F, Ibsen H, Kristianson K, Lederballe-Pedersen O, Lindholm LH, Nieminen MS, Omvik P, Oparil S, Wedel H, for the LIFE Study Group: Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol. Lancet 2002;359:995-1003. 64. Skoog T, Dichtl W, Boquist S, Skoglund-Andersson C, Karpe F, Tang R, Bond MG, de Faire U, Nilsson J, Eriksson P, Hamsten A. Plasma tumour necrosis factor-alfa and early carotid atherosclerosis in healthy middle-aged men. Eur Heart J 2002;23:376-83. 65. Hammar N, Kaprio J, Hagström U, Alfredsson L, Koskenvou M, Hammar T. Migration and mortality – a 20 year follow-up of Finnish twin pairs with migrant co-twins in Sweden. J Epidemiol Community Health 2002;56:362-6. 66. Hammar N, Linnersjö A, Alfredsson L, Dammström BG, Johansson M, Eliasch E. Cancer incidence in airline and military pilots in Sweden 1961-1996. Aviat Space Environ Med 2002;73:2-7. 67. Åkerstedt T, Knutsson A, Westerholm P, Theorell T, Kecklund G, Alfredsson L.Sleep disturbances, work stress and work hours. A cross-sectional study. J Psychosom Res 2002;53:741-8. 68. Fredriksson K, Ahlberg-Hultén G, Alfredsson L, Josephsson M, Kilbom Å,Wigaeus-Hjelm E, Wiktorin C, Vingård E and the MUSIC/Norrtälje Study Group. Work environment and neck and shoulder pain: the influence of exposure time. Results from a population based case-control study. Occup Environ Med 2002;59:182-8.

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Bilaga 4: Publikationer (original publikationer, reviews, skrifter i icke-refereegranskade tidskrifter) vid IMM per verksamhetsrområde 2000-2002

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69. Jartti L, Rönnemaa T, Kaprio J, Järvisalo MJ, Toikka JO, Marniemi J, Hammar N, Alfredsson L, Saraste M, Hartiala J, Koskenvou M, Raitakari OT. Population-based twin study of the effects of migration from Finland to Sweden on endothelial function and intima-media thickness. Arterioscler Thromb Vasc Biol 2002;22:832-7. 70. Vingård E, Mortimer M, Wiktorin C, Pernold G, Fredriksson K, Németh G, Alfredsson L. Seeking Care for Low Back Pain in the General Population: A Two-Year Follow-up Study: Results From the MUSIC-Norrtalje Study. Spine 2002;27:2159-65. 71. Åkerstedt T, Knutsson A, Westerholm P, Theorell T, Alfredsson L, Kecklund G. Work organisation and unintentional sleep: results from the WOLF study. Occup Environ Med 2002;59:595-600. 72. Alfredsson L, Hammar N, Fransson E, de Faire U, Knutsson A, Hallqvist J, Theorell T, Westerholm P. Job strain and major risk factors for coronary heart disease among employed males and females in a Swedish study on work, lipids and fibrinogen. Scand J Work Environ Health 2002;28:238-48. 73. Blumenthal JA, Sherwood A, Gullette EC, Georgiades A, Tweedy D. Biobehavioral approaches to the treatment of essential hypertension. J Consult Clin Psychol 2002;70:569-89. 74. Hinderliter A, Sherwood A, Gullette EC, Babyak M, Waugh R, Georgiades A, Blumenthal JA. Reduction of left ventricular hypertrophy after exercise and weight loss in overweight patients with mild hypertension. Arch Intern Med 2002;162:1333-9. 75. Sherwood A, Gullette EC, Hinderliter A, Georgiades A, Babyak M, Waugh R, Blumenthal JA. Relationship of clinic, ambulatory, and laboratory stress blood pressure to left ventricular mass in overweight men and women with high blood pressure. Psychosom Med 2002;64:247-57. 76. Michels KB, Holmberg L, Bergkvist L, Wolk A. Coffee, tea, and caffeine consumption and breast cancer incidence in a cohort of Swedish women. Ann Epidemiol 2002; 12:21-6. 77. Norman A, Moradi T, Gridley G, Dosemeci M, Rydh B, Nyren O, Wolk A. Occupational physical activity and risk for prostate cancer in a nationwide cohort study in Sweden. Br J Cancer 2002; 86:70-5. 78. Missmer SA, Smith-Warner SA, Spiegelman D, Yaun SS, Adami HO, Beeson WL, van Den Brandt PA, Fraser GE, Freudenheim JL, Goldbohm RA, Graham S, Kushi LH, Miller AB, Potter JD, Rohan TE, Speizer FE, Toniolo P, Willett WC, Wolk A, Zeleniuch-Jacquotte A, Hunter DJ. Meat and dairy food consumption and breast cancer: a pooled analysis of cohort studies. Int J Epidemiol 2002; 31:78-85. 79. Terry P, Wolk A, Vainio H, Weiderpass E. Fatty fish consumption lowers the risk of endometrial cancer: a nationwide case-control study in Sweden. Cancer Epidemiol Biomarkers Prev 2002; 11:143-5. 80. Norman A, Bellocco R, Vaida F, Wolk A. Total physical activity in relation to age, body mass, health and other factors in a cohort of Swedish men. Int J Obes Relat Metab Disord 2002; 26:670-5. 81. Serafini M, Bellocco R, Wolk A, Ekstrom AM. Total antioxidant potential of fruit and vegetables and risk of gastric cancer. Gastroenterology 2002; 123:985-91. 82. Terry P, Vainio H, Wolk A, Weiderpass E. Dietary factors in relation to endometrial cancer: a nationwide case-control study in Sweden. Nutr Cancer 2002; 42:25-32. 83. Michels KB, Wolk A. A prospective study of variety of healthy foods and mortality in women. Int J Epidemiol 2002; 31:847-54. 84. Terry P, Baron JA, Bergkvist L, Holmberg L, Wolk A. Dietary calcium and vitamin D intake and risk of colorectal cancer: a prospective cohort study in women. Nutr Cancer 2002; 43:39-46. 85. van den Brandt P, Voorrips L, Hertz-Picciotto I, Shuker D, Boeing H, Speijers G, Guittard C, Kleiner J, Knowles M, Wolk A, Goldbohm A. The contribution of epidemiology. Food Chem Toxicol 2002; 40:387-424. 86. Ahlbom A, Feychting M. Current thinking about risks from currents. The Lancet 2001;357:1143-1144

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Bilaga 4: Publikationer (original publikationer, reviews, skrifter i icke-refereegranskade tidskrifter) vid IMM per verksamhetsrområde 2000-2002

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87. Bjessmo S, Ivert T, Flink H, Hammar N. Early and late mortality in relation to Braunwald class after surgery for unstable angina. JACC. Am Heart J 2001;141:9-14. 88. Baron JA, Farahmand BY, Weiderpass E, Michaelsso K, Alberts A, Persson I, et al. Cigarette smoking, alcohol consumption and risk of hip fracture in women. Arch Intern Med 2001;161(7);983-988. 89. Bergström A, Terry P, Lindblad P, Lichtenstein P, Ahlbom A, Feychting M, Wolk A. Physical activity and risk of renal cell cancer. International Journal of Cancer 2001;92:155-157. 90. Feychting M, Plato N, Nise G, Ahlbom A. Paternal occupational exposures and childhood cancer. Environmental Health Perspectives 2001;109:193-196. 91. Hammar N, Andersson T, Reuterwall C, Nilsson T, Knutsson A, Hallqvist J, Ahlbom A. Geographical differences in the incidence of acute myocardial infarction in Sweden. Analyses of possible causes using two parallel case-control studies. J Intern Med 2001;249:137-144. 92. Hogstedt C, Ahlbom A, Aragon A, Castillo L, Kautsky N, Liden C, Lundberg I, Sundin P, Tedengren M, Thorn A, Wesseling C. Experiences from long-term research cooperation between Costa Rican, Nicaraguan, and Swedish researchers. Int J Occup Environ Health 2001 Apr-;7:130-5. 93. Håkansson N, Floderus F, Gustavsson P, Feychting M, Hallin N. Exposure to UV-light and cancer incidence among Swedish construction workers. Epidemiology 2001;12:552-7. 94. Johansson M, Rasmussen F. Birthweight and body mass index in young adulthood. The Swedish young male twins study. Twin Research 2001;4:400-405. 95. Larsen F, Pehrsson SK, Hammar N, Sköld CM, Izumi T, Nagai S, Shigematsu M, Eklund A. ECG-abnormalities in Japanese and Swedish patients with sarcoidiosis. A comparison. Sarcoidosis Vasc Diffuse Lung Dis 2001;18:284-8. 96. Leander K, Hallqvist J, Reuterwall C, Ahlbom A, de Faire U. Family history of coronary heart disease, a strong risk factor for myocardial infarction interacting with other cardiovascular risk factors: results from the Stockholm Heart Epidemiology Program (SHEEP). Epidemiology 2001;12:215-221. 97. Michaelsson K, Baron JA, Farahmand BY, Ljunghall S. Influence of parity and lactation on hip fracture risk. Am J Epidemiol 2001;153:1166-72. 98. Moller J, Ahlbom A, Hulting J, Diderichsen F, de Faire U, Reuterwall C, Hallqvist J. Sexual activity as a trigger of myocardial infarction. A case-crossover analysis in the Stockholm Heart Epidemiology Programme (SHEEP). Heart 2001 ;86:387-90 99. Nilsson L, Bergman U, Diwan V, Farahmand BY, Persson PG, Tomson T. Antiepileptic drug therapy and its management in sudden unexpected death in epilepsy: a case-control study. Epilepsia 2001;42(5):667-73 100. Ojajärvi A, Partanen T, Ahlbom A, Boffetta P, Hakulinen T, Jourenkova N, Kauppinen T, Kogevinas M, Vainio H, Weiderpass E & Wesseling C. Risk of pancreatic cancer inworkers exposed to chlorinated hydrocarbon solvents and related compounds: a meta-analysis. Am J Epidem 2001;153:841-850. 101. Terry P, Ekbom A, Lichtenstein P, Feychting M, Wolk A. Long-term tobacco smoking and colorectal cancer in a prospective cohort study. Int J Cancer 2001;91:585-7. 102. Terry P, Lichtenstein P, Feychting M, Ahlbom A, Wolk A. Fatty fish consumption and risk of prostate cancer. Lancet 2001;357:1764-6. 103. Wesseling C, Hogstedt C, Fernancez P, Ahlbom A. Time trends of occupational pesticide-related injuries in Costa Rica, 1982-. Interntional Journal of Occupational and Environmental Health 2001;7:1-6. 104. Rosengren A, Spetz C-L, Köster M, Hammar N, Alfredsson L, Rosén M. Sex differences in survival after myocardial infarction in Sweden. Data from the Swedish national acute myocardial infarction register. European Heart J 2001;22:314-322.

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105. Ösby U, Hammar N, Brandt L, Wicks S, Thinsz Z, Ekbom A, Sparén P. Time trends in first admissions for schizofrenia and paranoid psychosis in Stockholm county, Sweden. Scizophr Res 2001;47(2-3):247-54. 106. Almqvist C, Wickman M, Perfetti L, Berglind N, Renström A, Hedrén M, Larsson K, Hedlin G, Malmberg P: Worsening of asthma in children allergic to cats, after indirect exposure to cat at school. Am J Respir Crit Care Med 2001;163:694-698. 107. Bellander T, Berglind N, Gustavsson P, Jonson T, Nyberg F, Pershagen G, Järup L: Using geographic information systems to assess individual historical exposure to air pollution from traffic and house heating in Stockholm. Environ Health Perspect 2001;109:633-639. 108. Bornehag CG, Blomquist G, Gyntelberg F, Järvholm B, Malmberg P, Nordvall L, Nielsen A, Pershagen G, Sundell J: Dampness in buildings and health (NORDDAMP). Indoor Air 2001;11:72-86. 109. Böhme M, Svensson Å, Kull I, Nordvall L, Wahlgren C-F: Clinical features of atopic dermatitis at two years of age: a prospective, population-based case-control study. Acta Derm Venereol 2001;81:193-197. 110. Doi M, Nakamura Y, Sakashita T, Ogiu N, Lagarde F, Falk R: Lifetime risk of lung cancer due to radon exposure projected to Japanese and Swedish populations. Health Phys 2001;80:552-562. 111. Emenius G, Larsson PH, Wickman M, Härfast B: Dispersion of horse allergen in the ambient air, detected with sandwich ELISA. Allergy 2001;56:771-774. 112. Hou SM, Fält S, Yang K, Nyberg F, Pershagen G, Hemminki K, Lambert B: Differential interactions between GSTM1 and NAT2 genotypes on aromatic DNA adduct level and HPRT mutant frequency in lung cancer patients and population controls. Cancer Epidem Biomark Prev 2001;10:133-140. 113. Hou SM, Fält S, Nyberg F, Pershagen G, Lambert B: Interaction between GSTT1 genotype and smoking on lung cancer risk. Chemico-Biological Interactions 2001;133:106-8. 114. Hou SM, Fält S, Nyberg F: Glutathione S-Transferase T1-null genotype interacts synergistically with heavy smoking on lung cancer risk. Env Mol Mutagen 2001;38:83-86. 115. Håkansson N, Floderus B, Gustavsson P, Feychting M, Hallin N: Occupational sunlight exposure and cancer incidence among Swedish construction workers. Epidemiology 2001;12:552-7. 116. Klintberg B, Berglund N, Lilja G, Wickman M, v Hage Hamsten M: Fewer allergic respiratory disorders among farmers’ children in a closed birth cohort from Sweden. Eur Respir J 2001;17:1151-7. 117. Kwon HJ, Cho SH, Nyberg F, Pershagen G: Effects of ambient air pollution on daily mortality in a cohort of patients with congestive heart failure. Epidemiology 2001;12:413-19. 118. Lagarde F, Axelsson G, Damber L, Mellander H, Nyberg F, Pershagen G: Residential radon among never smokers in Sweden. Epidemiology 2001;12:396-404. 119. Lewis S, Brennan P, Nyberg F, Ahrens W, Constantinescu V, Mukeria A, Benhamou S, Batura-Gabryel H, Brüske-Hohlfeld, I, Simonato L, Menezes, Boffetta P: Dietary intake of isothiocyanates: Evidence of a joint effect with glutathione S-transferase polymorphisms in lung cancer risk. Cancer Epidemiol Biomark Prev 2001;10:1105-6. 120. Melén E, Wickman M, Nordvall SL, v Hage Hamsten M, Lindfors A: Influence of early and current environmental exposure factors on sensitization and outcome of asthma in pre-school children. Allergy 2001;56:646-52. 121. Nilsson S, Carstensen JM, Pershagen G: Mortality among male and female smokers in Sweden: A 33-year follow-up. J Epidemiol Commun Health 2001;55:825-30. 122. Nylen L, Voss M, Floderus B: Mortality among women and men relative to unemployment, part time work, overtime work, and extra work: a study based on data from the Swedish twin registry. Occup Environ Med 2001;58:52-7.

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123. Pershagen G: Environmental public-health surveillance systems for chemical incidents. Lancet 2001;357:411-12. 124. Pignatelli B, Li CQ, Boffetta P, Chen Q, Ahrens W, Nyberg F, et al.: Nitrated and oxidized plasma proteins in smokers and lung cancer patients. Cancer Research 2001;61:778-84. 125. Rosenlund M, Berglind N, Gustavsson A, Reuterwall C, Hallqvist J, Nyberg F, Pershagen G: Environmental tobacco smoke and myocardial infarction among never-smokers in the Stockholm heart epidemiology program (SHEEP). Epidemiology 2001;12:558-564. 126. Rosenlund M, Berglind N, Pershagen G, Järup L, Bluhm G: Increased prevalence of hypertension in a population exposed to aircraft noise. Occup Environ Med 2001;58:769-73. 127. Simonato L, Agudo A, Ahrens, Benhamou E, Benhamou S, Boffetta P, Brennan P, Darby S, Forastiere F, Fortes C, Gaborieau V, Gerken M, Gonzales C, Jöckel K-H, Kreuzer M, Merletti F, Nyberg F, Pershagen G, Pohlabeln H, Rösch F, Whitley E, Wichmann H-E, Zambon P: Lung cancer and cigarette smoking in Europe: an update of risk estimates and an assessment of intercountry heterogeneity. Int J Cancer 2001;91:876-887. 128. Svartengren M, Wickman M: Atopy-related diseases. Allergy 2001;56:267-9. 129. Westberg HB, Selden AI, Bellander T: Exposure to chemical agents in Swedish aluminum foundries and aluminum remelting plats – a comprehensive survey. Appl Occup Environ Hyg 2001;16:66-77. 130. Wickman B, Björkstén B, Hattevig G, Lilja G, Johansson SGO: Both risky and “healthy” factors in the allergy prevention counseling. Läkartidningen 2001;98:5656-60. 131. Wickman M, Svartengren M: Allergen exposure and asthma. Lancet 2001;357:1042-3. 132. Voss M, Floderus B, Diderichsen F: Physical, psychosocial, and organizational factors relative to sickness absence: a study based on Sweden Post. Occup Environ Med 2001;58:178-84. 133. Voss M, Floderus B, Diderichsen F: Changes in sickness absenteeism following the introduction of a qualifying day for sickness benefit-findings from Sweden Post. Scand J Public Health 2001;29:166-74. 134. Karpe F, Boquist S, Tang R, Bond GM, de Faire U, Hamsten A. Remnant lipoproteins are related to intima-media thickness of the carotid artery independently of LDL cholesterol and plasma triglycerides. J Lipid Res 2001; 42:17-21. 135. Forsberg L, Lyrenäs L, de Faire U, Morgenstern R. A common functional C-T substitution polymorphism in the promoter region of the human catalase gene influences transcription factor binding, reporter gene transcription and is correlated to blood catalase levels. Free Radic Biol Med 2001;30:500-505. 136. Wu R, Lemne C, de Faire U, Frostegård J. Antibodies to Lysophosphatidylcholine are decreased in borderline hypertension. Hypertension 2001;37:154-159. 137. Bennet AM, Näslund TI, Morgenstern R, de Faire U. Bioinformatic and experimental tools for identification of single-nucleotide polymorphisms in genes with a potential role for the development of the insulin resistance syndrome. J Intern Med 2001;249:127-136. 138. Leander K, Hallqvist J, Reuterwall C, Ahlbom A, de Faire U. Family history of coronary heart disease, a strong risk factor for myocardial infarction interacting with other cardiovascular risk factors: results from the Stockholm Heart Epidemiology Program (SHEEP). Epidemiology 2001;12:215-221. 139. Hübinette A, Cnattingius S, Ekbom A, de Faire U, Kramer M, Lichtenstein P. Birthweight, early environment, and genetics: a study of twins discordant for acute myocardial infarction. Lancet 2001;357:1997-2001. 140. Iliadou A, Lichtenstein P, de Faire U, Pedersen NL. Variation in genetic and environmental influences in serum lipid and apolipoprotein levels across the lifespan in Swedish male and female twins. Am J Med Genet 2001;102:48-58.

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141. Rau R, Georgiades A, Fredriksson M, Lemne C, de Faire U. Psychosocial work characteristics and perceived control in relation to cardiovascular rewind at night. J Occup Health Psychol 2001;6:171-181. 142. Lindholm LH, Anderson H, Ekbom T, Hansson L, Lanke J, Dahlöf B, de Faire U, Forsén K, Hedner T, Linjer E, Scherstén B, Wester PO, Möller TR. Relation between drug-treatment and cancer in hypertensives in the Swedish Trial in Old Patients with Hypertension 2: a 5-year, prospective, randomised, controlled trial. Lancet 2001;358:539-544. 143. Rosengren A, Spetz CL, Köster M, Hammar N, Alfredsson L, Rosén M. Sex differences in survival after myocardial infarction in Sweden. Data from the Swedish National Acute Myocardial Infarction register. Eur Heart J 2001 ;22:314-322. 144. Berglund A, Alfredsson L, Jensen I, Cassidy JD, Nygren Å. The association between exposure to a rear-end collision and future health complaints. J Clin Epidemiol 2001 54:851-6. 145. Tornqvist EW, Kilbom A, Vingard E, Alfredsson L, Hagberg M, Theorell T, Waldenstrom M, Wiktorin C, Hogstedt C. The influence on seeking care because of neck and shoulder disorders from work-related exposures. Epidemiology 2001;12:537-45. 146. Bildt C, Alfredsson L, Punnett L, Theobald H, Torgén M, Wikman A. Effects of drop out in a longitudinal study of musculoskeletal disorders. Occup Environ Med 2001 ;58:194-199. 147. Terry P, Lagergren J, Wolk A, Nyrén O. Drinking hot beverages is not associated with risk of oesophageal cancers in a Western population. Br J Cancer 2001;84:120-121.

148. Bergström A, Pisani P Tenet V, Wolk A, Adami HO. Overweight as an avoidable cause of cancer in Europe. Int J Cancer 2001;91:421-30.

149. Wolk A, Gridley G, Svensson M, Nyrén O, McLaughlin JK, Adami HO. A prospective study of obesity and cancer risk. Cancer Causes Control 2001;12:13-21.

150. Smith-Warner SA, Spiegelman D, Yaun S-S, Adami HO, Beeson WL, van den Brandt PA, Folsom AR, Fraser GE, Freudenheim JL, Goldbohm RA, Graham S, Miller AB, Potter JD, Rohan TE, Speizer FE, Toniolo PG, Willett WC, Wolk A, Zeleniuch-Jacquotte A, Hunter DJ. Intake of fruit and vegetables and risk of breast cancer. A pooled analysis of cohort studies. JAMA 2001;285:769-76.

151. Terry P, Lagergren J, Ye W, Wolk A, Nyrén O. Inverse association between intake of cereal fiber and risk of gastric cardia cancer. Gastroenterology 2001;120:387-91.

152. Terry P, Ekbom A, Lichtenstein P, Feychting M, Wolk A. Long-term tobacco smoking and colorectal cancer in a prospective cohort study. Int J Cancer 2001;91:585-587.

153. Michels KB, Holmberg L, Bergkvist L, Ljung H, Bruce Å, Wolk A. Dietary antioxidant vitamins, retinol, and breast cancer incidence in a cohort of Swedish women. Int J Cancer 2001;91:563-567.

154. Wolk A, Furuheim M, Vessby B. Fatty acid composition of adipose tissue and serum lipids are valid biological markers of dairy fat intake in men. J Nutrition 2001;131:828-833.

155. Bergström A, Lindblad P, Wolk A. Birth weight and risk of renal cell cancer. Kidney Int 2001;59:1110-13.

156. Bergström A, Terry P, Lindblad P, Lichtenstein P, Ahlbom A, Feychting M, Wolk A. Physical activity and risk of renal cell cancer. Int J Cancer 2001;92:155-57.

157. Norman A, Bellocco R, Bergström A, Wolk A. Validity and reproducibility of self-reported total physical activity and energy expenditure – differences by relative weight. Int J Obes 2001;25:682-88.

158. Smith-Warner SA, Spiegelman D, Adami HO, Beeson L, van den Brandt PA, Folsom AR, Fraser GE, Freudenheim JL, Goldbohm RA, Graham S, Kushi LH, Miller AB, Rohan TE, Speizer FE, Toniolo P, Willett WC, Wolk A, Zeleniuch-Jacquotte A, Hunter DJ. Types of dietary fat and breast cancer: A pooled analysis of cohort studies Int J Cancer 2001;92:767-74.

159. Terry P, Giovannucci E, Michels K, Bergkvist L, Hansen H, Holmberg L, Wolk A. Fruit, vegetables, dietary fiber, and risk of colorectal cancer. JNCI 2001;93:525-33.

160. Terry P, Lichtenstein P, Feychting M, Ahlbom A, Wolk A. Fatty fish consumption and risk of prostate cancer. Lancet 2001;357:1764-66.

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161. Terry P, Bergkvist, Holmberg L, Wolk A. Coffee consumption and risk of colorectal cancer in a population-based prospective cohort of Swedish women. Gut 2001;49: 87-90.

162. Wolk A, Granath F, Andersson SO, Trichopoulos D, Adami HO. Authors reply to ”Improving the sensitivity of prostate cancer screening”. Correspondence Lancet 2001;357:1201-02.

163. Terry P, Wolk A, Persson I, Magnusson C. Brassicae vegetables and breast cancer risk. JAMA 2001;285:2975-77.

164. Messerer M, Johansson SE, Wolk A. Use of dietary supplements and natural remedies increased dramatically during the 1990s. J Internal Med 2001;250:160-66.

165. Terry P, Giovannucci E, Bergkvist L, Holmberg L, Wolk A. Body weight and colorectal cancer risk in a cohort of Swedish women: relation varies by age and cancer site. Br J Cancer 2001;85:346-9.

166. Terry P, Bergkvist L, Holmberg L, Wolk A. No association between fat and fatty acids intake and risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev 2001;10:913-14.

167. Terry P, Lagergren J, Hansen H, Wolk A, Nyrén O. Fruit and vegetable consumption in the prevention of esophageal and cardia cancers. Eur J Cancer Prev 2001;10:365-69.

168. Bergström A, Hsieh C-C, Lindblad P, Lu C-M, Cook NR, Wolk A. Obesity and renal cell cancer – a quantitative review. Br J Cancer 2001;85:984-90.

169. Terry P, Hu F, Hansen H, Wolk A. A prospective study of major dietary patterns and colorectal cancer risk in women. Am J Epidemiol 2001;154:1143-9.

170. Messerer M, Johansson SO, Wolk A. Sociodemographic and health behaviour factors among dietary supplement and natural remedy users. Eur J Clin Nutr 2001;55:1104-10.

171. Terry P, Lagergren J, Ye W, Wolk A, Nyrén O. Correspondence: Inverse association between intake of cereal fiber and risk of gastric cardia cancer. Gastroenterology 2001;121:1024-25.

172. Terry P, Suzuki R, Hu F, Wolk A. A prospective study of major dietary patterns and risk of breast cancer. Cancer Epidemiol Biomarkers Prev 2001;10:1281-85.

173. Terry P, Wolk A. Tea consumption and the risk of colorectal cancer in Sweden. Nutr Cancer 2001;39:176-79.

174. Terry P, Terry JB, Wolk A. Fruit and vegetable consumption in the prevention of cancer: an update. J Internal Med 2001;250:280-90.

175. Ahlbom A, Day N, Feychting M, Roman E, Skinner J, Dockerty J, Linet M, McBride M, Michaelis J, Olsen JH, Tynes T, Verkasalo PK. A pooled analysis of magnetic fields and childhood leukaemia. British Journal of Cancer 2000;83:692-698. 176. Bjessmo S, Hammar N, Sandberg E, Ivert T. Reduced risk of coronary artery bypass surgery for unstable angina during a six-year period. Eur J Cardiothorac Surg 2000;18:338-92. 177. Carlsson S, Hammar N, Efendic S, Östensson C-G, Persson P-G, Grill V. Alcohol consumption, Type 2 diabetes mellitus and impaired glucose tolerance in middle-aged Swedish men. Diabetic Medicine 2000;17:776-81. 178. Farahmand, B.Y., et al., Socioeconomic status, marital status and hip fracture risk: a population-based case-control study. Osteoporos Int 2000;11(9):803-8. 179. Farahmand BY, Persson P-G, Michaëlsson, Baron A John, Alberts Akke, Moradi T, Ljunghall S. Physical activity and hip fracture: a population-based case-control study. Int J of Epidem 2000;29:308-314. 180. Feychting M, Ahlbom A. With regard to the relative merits of contemporary measurements and historical calculated fields in the Swedish childhood cancer study. Epidemiology 2000;11:357-358. (letter) 181. Feychting M, Ahlbom A. Re: Jaffa et al. The relative merits of contemporary measurements and historical calculated fields in the Swedish childhood cancer study. Epidemiology 2000;11:357-358.

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182. Feychting M, Floderus B, Ahlbom A. Parental occupational exposure to magnetic fields and childhood cancer (Sweden). Cancer Causes and Control 2000;11:151-156. 183. Forssén UM, Feychting M, Rutqvist LE, Floderus B, Ahlbom A. Occupational and residential magnetic field exposure and female breast cancer. Epidemiology 2000;11:24-29. 184. Hallqvist J, Möller J, Ahlbom A, Diderichsen F, Reuterwall C, de Faire U. Does heavy physical exertion trigger myocardial infarction? A case-crossover analysis nested in a population based case-referent study (SHEEP). Am J Epidemiology 2000;151:459-467. 185. Hahn R, Farahmand BY, Hallin A, Hammar N, Persson P-G. Incidence of acute myocardial infarction and cause-specific mortality after transurethral treatments of prostatic hypertrophy. Urology 2000;55:236-40. 186. Hjern A, Haglund B, Rasmussen F, Rosén M. Socio-economic differences in day care arrangements and use of medical care and antibiotics in Swedish preschool children. Acta Paediatr 2000; 89: 1250-1256. 187. Leon D A, Johansson M, Rasmussen F. Gestational age and Growth Rate of Fetal Mass are inversely associated with Systolic Blood Pressure in Young Adults. An Epidemiologic Study of 165,136 Swedish 18-year old men. Am J Epidemiol 2000; 152:597-604. 188. Linnersjö A, Gustavsson A, Reuterwall C, Hammar N. Recent time trends in acute myocardial infarction in Stockholm, Sweden. Int J Cardiol. 2000;76:17-21. 189. Ojajärvi IA, Partanen TJ, Ahlbom A, Bofetta P, Hakulinen T, Jourenkova N, Kauppinen TP, Kogevinas M, Porta M, Vainio HU, Wederpass-Petersen E & Wesseling C. Occupational exposures and pancreatic cancer: A meta-analysis. Occupational and Environmental Medicine 2000;57:316-324. 190. Rasmussen F, Johansson M. Increase in the Prevalence of Overweight and Obesity from 1995 to 1998 among 18-year-old Males in Sweden. Acta Paediatr 2000;89:888-889. 191. Rasmussen F, Thorén K, Caines E, Andersson J, Tynelius P. Suitability of the Lang II Random Dot Stereotest for detecting manifest strabismus in 3-year-old children at child health centres in Sweden. Acta Paediatr 2000;89:824-829. 192. Rosén M, Alfredsson L, Hammar N, Kahan T, Spetz C-L, Ysberg A-S. Incidence, mortality and case fatality for acute myocardial infarction in Sweden 1987-1995. Results from the Swedish National AMI Register. J Intern Med 2000;248:159-64. 193. Wiman B, Andersson T, Hallqvist J, Reuterwall C, Ahlbom A and de Faire U. Plasma levels of tissue plasminogen activator/plasminogen activator inhibitor-1 complex and von willebrand factor are significant risk markers for recurrent myocardial infarction in the Stockholm Heart Epidemiology Program (SHEEP). Arteriosclerosis Thrombosis and Vascular Biology 2000;20:2019-2023. 194. Alfvén T, Elinder CG, Carlsson MD, Grubb A, Hellström L, Persson B, Pettersson C, Spång G, Schütz A, Järup L. Low level cadmium exposure and osteoporosis. J Bone Mineral Res 2000;15:1579-1586. 195. Andersson R, Pershagen G et al: Evaluation and use of epidemiological evidence for environmental health risk assessment: WHO Guideline Document. Environ Health Perspect 2000;108:997-1002. 196. Brennan P, Butler J, Agudo A, Benhamou S, Darby S, Nyberg F et al: Joint effect of diet and environmental tobacco smoke on risk of lung cancer among nonsmokers. J Natl Cancer Inst 2000;92:426-427. 197. Brennan P, Fortes C, Butler J, Agudo A, Benhamou S, Darby S, Gerken M, Jöckel KH, Kreuzer M, Mallone S, Nyberg F, et al.: A multicenter case-control study of diet and lung cancer among non-smokers. Cancer Causes Control 2000;11:49-58. 198. Böhme M, Svensson Å, Kull I, Wahlgren CF: Hanfin’s and Rajka’s minor criteria for atopic dermatitis: Which do 2-year-old children exhibit? J Am Acad Dermatol 2000:43:785-792.

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199. Emenius G, Korsgaard J, Wickman M: Window pane condensation and high indoor vapour contribution – markers of an unhealthy indoor climate? Clin Exp Allergy 2000;30:418-425. 200. Feychting M, Floderus B, Ahlbom A: Parental occupational exposure to magnetic fields and childhood cancer (Sweden). Cancer Causes Control 2000;11:151-6. 201. Forssén UM, Feychting M, Rutqvist LE, Floderus B, Ahlbom A: Occupational and residential magnetic field exposure and breast cancer in females. Epidemiology 2000; 11:24-9. 202. Gustavsson P, Jakobsson R, Nyberg F, Pershagen G, Järup L, Schéele P: Occupational exposure and lung cancer risk – a population-based case-referent study in Sweden. Am J Epidemiol 2000;152:32-40. 203. Hackman P, Hou SM, Nyberg F, Pershagen G, Lambert B: Mutational spectra at the hypoxanthine-guanine phosphoribosyltransferase (HPRT) locus in T-lymphocytes of nonsmoking and smoking lung cancer patients. Mutat Res 2000;468:45-61. 204. Husgafvel-Pursiainen K, Boffetta P, Kannio A, Nyberg F, Pershagen G, Mukeria A, Constantinescu V, Fortes C, Benhamou S: p53 mutations and exposure to environmental tobacco smoke in a multi-center study on lung cancer. Cancer Res 2000;60:2906-11. 205. Järup L, Hellström L, Alfvén T, Carlsson D, Grubb A, Persson B, Pettersson C, Schütz A, Spång G, Elinder CG. Low level cadmium exposure and kidney damage - the OSCAR study. Occup Environ Med 2000;57:668-672. 206. Lilja G, Wickman M: The immunology of fetuses and infants. Allergy 2000;55:589-90. 207. Malats N, Camus-Radon AM, Nyberg F, Ahrens W, Constantinescu V et al.: Lung cancer risk in non-smokers and GSTM1 and GSTT1 polymorphisms. Cancer Epidemiol Biomark Prev 2000;9:827-833. 208. Nyberg F, Gustavsson P, Järup L, Bellander T, Berglind N, Jakobsson R, Pershagen G: Urban air pollution and lung cancer in Stockholm. Epidemiology 2000:11:587-95. 209. Nyberg F: Misclassification of smoking status and lung cancer risk from environmental tobacco smoke in never-smokers. Lung Cancer 2000;29:47-48. 210. Pohlabeln H, Boffetta P, Ahren W, Merletti F, Agudo A, Benhamou E, Brüske-Holfeld I, Ferro G, Fortes C, Kreuzer M, Mendes A, Nyberg F, Pershagen G, Saracci R, Schmid G, Siemiatycki J, Simonato L, Whitley E, Wichmann HE, Winck C, Zambon P, Jöckel KH: Occupational risk for lung cancer among nonsmokers. Epidemiology 2000;11:532-8. 211. Svartengren M, Strand V, Bylin G, Järup L, Pershagen G: Short-term exposure to air pollution in a road tunnel enhances the asthmatic response to allergen. Eur Resp J 2000;15:716-24. 212. Whiteman DC, Murphy MF, Verkasalo PK, Page WF, Floderus B, Skytte A, Holm NV: Breast cancer risk in male twins: joint analyses of four twin cohorts in Denmark, Finland, Sweden and United States. Br J Cancer 2000;83:1231-3. 213. Hallqvist J, Möller J, Ahlbom A, Diderichsen F, Reuterwall C, de Faire U. Does heavy physical exertion trigger myocardial infarction? A case-crossover analysis nested in a population-based case-referent study. Am J Epidemiol 2000;151:459-467. 214. Ruotolo G, Båvenholm P, Brismar K, Efendic S, Ericsson CG, de Faire U, Nilsson J, Hamsten A. Serum insulin-like growth factor-I level is independently associated with coronary artery disease progression in young male survivors of myocardial infarction: beneficial effects of bezafibrate treatment. J Am Coll Cardiol 2000;35:647-654. 215. Nordström T, Ronaghi M, Forsberg L, de Faire U, Morgenstern R, Nyrén P. Direct analysis of single-nucleotide polymorphism on double-stranded DNA by pyrosequencing. Biotechnol Appl Biochem 2000;31:107-112. 216. Pockley AG, Wu R, Lemne C, Kiessling R, de Faire U, Frostegård J. Circulating heat shock protein 60 is associated with early cardiovascular disease. Hypertension 2000;36:303-307.

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217. Kjeldsen SE, Dahlöf B, Devereux RB, Julius S, de Faire U, Fyhrquist F, Ibsen H, Kristiansson K, Lindholm LH, Nieminen MS, Omvik P, Oparil S, Wedel H Lowering of blood pressure and predictors of response in patients with left ventricular hypertrophy: the LIFE study. Losartan Intervention for Endpoint. Am J Hypertens 2000;13:899-906. 218. Hansson L, Hedner T, Lund-Johansen P, Kjeldsen SE, Lindholm LH, Syvertsen JO, Lanke J, de Faire U, Dahlöf B, Karlberg BE. Randomised trial of effects of calcium antagonists compared with diuretics and beta-blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) study. Lancet 2000;356:359-365. 219. Wiman B, Andersson T, Hallqvist J, Reuterwall C, Ahlbom A, de Faire U. Plasma levels of tissue plasminogen activator/plasminogen activator inhibitor-1 complex and von Willebrand factor are significant risk markers for recurrent myocardial infarction in the Stockholm Heart Epidemiology Program (SHEEP) Study. Arterioscler Thromb Vasc Biol 2000;20:2019-2023. 220. Lindholm LH, Hansson L, Ekbom T, Dahlöf B, Lanke J, Linjer E, Scherstén B, Wester PO, Hedner T, de Faire U. Comparison of antihypertensive treatments in preventing cardiovascular events in elderly diabetic patients: results from the Swedish Trial in Old Patients with Hypertension-2. STOP Hypertension-2 Study Group. J Hypertens 2000;18:1671-1675. 221. Forsberg L, de Faire U, Marklund SL, Andersson PM, Stegmayr B, Morgenstern R. Phenotype determination of a common Pro-Leu polymorphism in human glutathione peroxidase 1. Blood Cells Mol Dis 2000;26:423-426. 222. Thorbjornsson CB, Alfredsson L, Fredriksson K, Michelsen H, Punnett L, Vingard E, Torgen M, Kilbom A. Physical and psychosocial factors related to low back pain during a 24-year period. A nested case-control analysis. Spine 2000;25:369-74. 223. Theorell T, Alfredsson L, Westerholm P, Falck B. Coping with unfair treatment at work – What is the relationship between coping and hypertension in middle-aged men and women?. an epidemiological study of working men and women in Stockholm (the Wolf study). Psychother Psychosom 2000;69:86-94. 224. Berglund A, Alfredsson L, Cassidy JD, Jensen I, Nygren Å. The association between exposure to a rear-end collision and future neck or shoulder pain: A cohort study. J Clin Epidemiol 2000;53:1089-94. 225. Vingård E, Alfredsson L, Hagberg M, Kilbom Å, Theorell T, Waldenström M, Wigeus-Hjelm E, Wiktorin C, Hogstedt C. To what extent do current and past physical and psychosocial occupational factors explain care-seeking for low back pain in a working population? Results from the usculoskeletal Intervention Center-Norrtalje Study. Spine 2000;25:493-500. 226. Hammar N, Alfredsson L, Rosén M, Spetz C-L, Kahan T, Ysberg A-S. A national record linkage to study acute myocardial infarction incidence and case fatality in Sweden. Int J Epidemiol 2001;30:S30-S34. 227. Rosén M, Alfredsson L, Hammar N, Kahan T, Spetz C-L, Ysberg AS. Attack rate, mortality and case-fatality for acute myocardial infarction in Sweden 1987-1995. Results from the National AMI Register Sweden. J Intern Med 2000;248:159-64. 228. Bildt C. Alfredsson L, Michélsen H, Punett L, Vingård E, Torgén M, Öhman A, Kilbom Å. Occupational and non-occupational risk indicators for incident and chronic low back pain in a sample of the Swedish general population during a 4-year period: An influence of depression?. Int J Beh Med 2000;7:372-392. 229. Fredriksson K, Alfredsson L, Bildt Torbjörnsson C, Punett L, Toomingas A, Torgén M, Kilbom Å. Risk factors for neck and shoulder disorder. A nested case-control study covering a 24 year period. Am J Ind Med 2000 ;38:516-28. 230. Ekström AM, Serafini M, Nyrén O, Hansson LE, Wolk A. Dietary antioxidant intake and the risk of cardia cancer and non-cardia cancer of the intestinal and diffuse types: a population-based case-control study in Sweden. Int J Cancer 2000;87:133-40.

231. Lissner L, Johansson SE, Qvist J, Rössner S, Wolk A. Social mapping of the obesity epidemic in Sweden. Int J Obes Relat Metab Disord 2000;24:801-805.

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232. Terry P, Lagergren J, Ye W, Nyrén O, Wolk A. Antioxidants and cancers of the esophagus and gastric cardia. Int J Cancer 2000;87:750-54.

233. van den Brandt PA, Spiegelman D, Yuan S-S, Adami HO, Beeson L, Folsom AR, Fraser G, Goldbohm RA, Graham S, Kushi LH, Marshall JR, Miller AB, Rohan T, Smith-Warner SA, Speizer FE, Willett W, Wolk A, Hunter DJ. Pooled analysis of prospective cohort studies on height, weight and breast cancer risk. Am J Epidemiol 2000;152:514-27.

234. Wolk A, Andersson SO, Mantzoros CS, Trichopoulos D, Adami HO. Can measurements of IGF-1 and IGFBP-3 improve the sensitivity of prostate-cancer screening? Lancet 2000;356:1902-1903.

235. Wicklund Glynn A, Michaëlsson K, Lind M, Wolk A, Aune M, Atuma S, Darnerud PO, Mallmin H. Organochlorines and bone mineral density in Swedish men from the general population. Osteoporosis Int 2000;11:1036-42.

236. Wicklund Glynn A, Wolk A, Aune M, Atuma S, Zettermark A, Maehle-Schmidt M, Darnerud PO, Becker W, Vessby B, Adami HO. Serum concentrations of organochlorines in Swedish men: a search for markers of exposure. Sci Total Environ 2000;263:197-208.

237. Terry P, Lagergren J, Wolk A, Nyrén O. Reflux-inducing dietary factors and risk of adenocarcinoma of the esophagus and gastric cardia. Nutr Cancer 2000;38:186-91.

Reviews Klareskog L, Lorentzen J, Padyukov L, Alfredsson L. Genes and environment in arthritis: can RA be prevented? Arthritis Res 2002;4 Suppl 3:S31-6. de Faire U. Adrenoreceptor genes and hypertension: contribution from genetic polymorphisms. J Hypertens 2002;20:1047-8. Lichtenstein P, de Faire U, Floderus B, Svartengren M, Svedberg P, Pedersen NL. The Swedish Twin Registry: a unique resource for clinical, epidemiological and genetic studies. J Intern Med 2002;252:184-205. Pershagen G: Environmental tobacco smoke is carcinogenic. Läkartidningen 2002:99:3227-8. Pershagen G: Can immunisation affect the development of allergy? Pediatr Allergy Immunol 2000;10:1-4. Ahlbom A. Neurodegenerative diseases, suicide and depressive symptoms in relation to EMF. Bioelectromagnetics 2001;(suppl 5):S132-S143. Ahlbom A, Cardis E, Green A, Linet M, Savitz D & Swerdlow A. Review of the epidemiological literture on EMF and health. Environmental Health Perspectives 2001;109(suppl 6):911-933. Forsberg L, de Faire U, Morgenstern R. Oxidative stress, human genetic variation, and disease. Arch Biochem Biophys 2001;389:84-93. Review. Nyberg F, Pershagen G: Epidemiologic studies on the health effects of ambient particulate air pollution. In: Pershagen G (ed): Particles in ambient air pollution – a health risk assessment. Scand J Work Environ Health 2000:26 Suppl:49-89. Pershagen G: Naivety of researchers’ and physicians’ contacts with tobacco industry. Only a few are aware of the manipulation they are exposed to by well-conducted campaigns. Läkartidningen 2002;99:2726-8. Farahamand BY, Michaelsson K, Baron JA, Persson PG, Ljunghall S. Body size and hip fracture risk. Swedish Hip Fracture study group 2000;11(2):214-9. Hammar N, Alfredsson L, Rosén M, Spetz C-L, Kahan T, Ysberg A-S. A national record linkage to study acute myocardial infarction incidence and case fatality in Sweden. Int J Epidemiol. 2001;30(Suppl 1):S30-4.

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Skrifter i icke refereegranskade tidskrifter. Alfredsson L, Fransson E. Job strain och hjärt-kärlsjukdom. I: Psykosocial belastning och riskfaktorer för hjärt-kärlsjukdom. Minisymposium i WOLF-projektet 8 februari 2001. Arbete och Hälsa 2002;7:1-2. Brostedt EM, Alfredsson L, Westerholm P, Knutsson A, de Faire U. Job strain och PAI-1. . I: Psykosocial belastning och riskfaktorer för hjärt-kärlsjukdom. Minisymposium i WOLF-projektet 8 februari 2001. Arbete och Hälsa 2002;7:3-6. Hasselhorn HM, Theorell T, Hammar N, Alfredsson L, Westerholm P. Olika sätt att mäta psykologiska krav och kontroll på arbetsplatsen. I: Psykosocial belastning och riskfaktorer för hjärt-kärlsjukdom. Minisymposium i WOLF-projektet 8 februari 2001. Arbete och Hälsa 2002;7:15-20. Hasselhorn HM, Theorell T, Hammar N, Alfredsson L, Westerholm P. Vad påverkar hjärt-kärl-riskfaktorer, “upplevelsen” eller de objektiva arbetsförhållandena? . I: Psykosocial belastning och riskfaktorer för hjärt-kärlsjukdom. Minisymposium i WOLF-projektet 8 februari 2001. Arbete och Hälsa 2002;7:21-6. Peter R, Alfredsson L, Hammar N, Siegrist J, Theorell T, Westerholm P. Obalans mellan ansträngning och belöning i arbetet och riskfaktorer för hjärt-kärlsjukdom – observationer baserade på data från WOLF-studien.I: Psykosocial belastning och riskfaktorer för hjärt-kärlsjukdom. Minisymposium i WOLF-projektet 8 februari 2001. Arbete och Hälsa 2002;7:31-8. Theorell T, Alfredsson L, Westerholm P, Falck B. Öppen och dold coping i förhållande till högt blodtryck hos medelålders män och kvinnor. I: Psykosocial belastning och riskfaktorer för hjärt-kärlsjukdom. Minisymposium i WOLF-projektet 8 februari 2001. Arbete och Hälsa 2002;7:39-46. Westerlund H, Theorell T, Alfredsson L. Hjärt-kärlriskfaktorer och organisatorisk instabilitet. . I: Psykosocial belastning och riskfaktorer för hjärt-kärlsjukdom. Minisymposium i WOLF-projektet 8 februari 2001. Arbete och Hälsa 2002;7:47-50. Åkerstedt T, Knutsson A, Westerholm P, Theorell T, Alfredsson L, Kecklund G. Att predicera sömnstörning, insomningsrisk och mental trötthet – tre delstudier. . I: Psykosocial belastning och riskfaktorer för hjärt-kärlsjukdom. Minisymposium i WOLF-projektet 8 februari 2001. Arbete och Hälsa 2002;7:51-4. Wolk A. Dietary factors and prostate cancer. Review Series. Urology 2002;3:2-6 Wolk A. Obesity and cancer of the prostate, gallbladder, oesophagus. Int J Obes Supp 2002 (supplent proceedings from 9th International Congress on Obesity, 24-29 August 2002, Sao Paulo, Brazil) Ahlbom A, Adami H-O, Ekbom A, Hagmar L, Ingelman-Sundberg M. Mediemissbrukarna skadar forskningens anseende. Läkartidningen 2001;42:4554-5. Ahlbom A, Feychting M. Biological effects, health consequences and standards for pulsed radiofrequency fields. Cancer epidemiological studies. In: Biological effects, health consequences and standards for pulsed radiofrequency fields. Matthes R, Bernhardt JH, Repacholi MH (eds). ICNIRP 11/2001. Page 161-7. Ahlbom A, Feychting M. Två nya studier om hälsorisker vid mobiltelefoni, men fortfarande otillräcklig kunskap. Läkartidningen 2001;98:410-411. Feychting M, Ahlbom A. Exposure assessment in epidemiological studies – sensitivity, specificity and the impact of non-differential exposure misclassification. In: Biological effects, health consequences and standards for pulsed radiofrequency fields. Matthes R, Bernhardt JH, Repacholi MH (eds). ICNIRP 11/2001. Page 109-15. Feychting M, Ahlbom A. Hälsoeffekter av magnetfält? Stark epidemiologi men okända mekanismer. Läkartidningen 2001;98:5168. Feychting M, Ahlbom A. Kan ljusexponering påverka risken för bröstcancer? Läkartidningen 2001;98:4316-4318.

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Ahlbom A. Fortfarande möjligt samband mellan magnetfält och cancer. Läkartidningen 2000;97:677. Ahlbom A, Feychting M. Replik: Försiktighetsprincipen och mobiltelefoni – inget skäl att nu begränsa användningen. Läkartidningen 2000;97:3910. Ahlbom A, Feychting M. Hur farlig är mobiltelefonen? Medicinsk kommentar. Läkartidningen 2000;97:26-27. Feychting M. Electromagnetic field exposure and childhood leukemia. L’Ospedale Maggiore 2000;94(4):330-334. Ivert T, Sandberg E, Hammar N. Fetma ökar ej risken vid kranskärlskirurgi. Läkartidningen. 2000;97:972-4. Hammar N, Eliasch H. Ökar flygning risken för cancer? Nordisk forskning söker svar. Flygvapennytt 2000;4:40-41. AWTerry P, Lindblad J, and Larhammar D. [Reply: it can't be worse!]. Lakartidningen 2000;97(48):5681. Terry P, Lindblad J, and Larhammar D. [Responsible popular scientific information--what should be required?]. Lakartidningen 2000;97(42):4755-8.

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Verksamhetsområde Miljömedicin Originalpublikationer 1. Andersson P, McGurie J, Rubio C, Reiland S, Petterson S, Hanberg A, Poellinger L (2002): A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors. Proc Natl Acad Sci USA, 99, 9990-9995. 2. Huang P, Ceccatelli S, Håkansson H, Grandison L, Rannug A (2002): Constitutive and TCDD-induced expression of Ah receptor-responsive genes in the pituitary. NeuroToxicology, 129, 1-11. 3. Rudén C (2002): The use of mechanistic data and the handling of scientific uncertainty in carcinogen risk assessment – the trichloroethylene example. Reg Toxicol Pharmacol 35, 80-94. T, O 4. Rudén C (2002): Scutinizing three trichloroethylene carcinogenicity classifications in the Europena Union - Implications for the risk assessment process. Int J Toxicol, 21, 441-450. 5. Sand S, Falk Filipsson A, Victorin K (2002): Evaluation of the benchmark dose method for dichotomous data: Model dependence and model selection. Reg Tox Pharmacol 36, 184-197. 6. Stern N, Öberg M, Casabona H, Trossvik C, Manzoor E, Johansson N, Lind M, Blomgren K, Jensen S, Haglund P, Wesén C, Örberg J, Feinstein R, Johansson A, Chu I, Poon R, Yagminas A, Brouwer A, Jones B, Håkansson H (2002): Subchronic toxicity of Baltic herring oil and its fractions in the rat. II) Clinical observations and toxicological parameters. Pharmacol Toxicol, 91, 220-231. 7. Öberg M, Stern N, Jensen S, Wesén C, Haglund P, Casabona H, Johansson N, Blomgren K, Håkansson H (2002): Subchronic toxicity of Baltic herring oil and its fractions in the rat. I) Fractionation and levels of organohalogen pollutants. Pharmacol Toxicol, 91, 232-244. 8. Öberg M, Sjödin S, Casabona H, Nordgren I, Klasson-Wehler E, Håkansson H (2002): Tissue distribution and half-lives of individual polychlorinated biphenyls and serum levels of 4-hydroxy-2,3,3’,4’,5-pentachlorobiphenyl in the rat. Toxicol. Sci, 70: 171-182. 9. Ask K, Åkesson A, Berglund M, Vahter M. (2002) Inorganic mercury and methylmercury in placentas of Swedish women. Environ Health Perspect 110(5), 523-526. 10. Concha G, Vogler G, Nermell B, Vahter M. (2002) Intra-individual variation in the metabolism of inorganic arsenic. Int Arch Occup Environ Health 75, 576-580. 11. Vahter M. (2002) Mechanisms of arsenic biotransformation. Toxicology 181-182, 211-217. 12. Dabrio M., Rodriguez A.R., Bordin G., Bebianno M. J. De Ley M., Sestakova I., Vasak M. and Nordberg M. (2002) Recent Developments in Quantification Methods for Metallothionein. Journal Inorganic Biochemistry 88, 123-134 13. Johansson N., Basun H., Winblad B., Nordberg M. (2002) Relationship between mercury concentration in blood, and cognitive performance, bloodpressure, in an elderly urban population, BioMetals 15, 189-195 14. Jin T, Nordberg M,Frech W,Dumont X,Bernard A,Ye T,Kong Q, Wang M, Li P, Lundström N-G, Li Y, and Nordberg GF (2002) Cadmium biomonitoring and renal dysfunction among a population environmentally exposed to cadmium from smelting in China (ChinaCad) BioMetals 15, 397-410. 15. Åkesson A, Bjellerup P, Berglund M, Bremme K, Vahter M. (2002) Soluble transferrin receptor: longitudinal assessment from pregnancy to postlactation. Obstetrics & Gynecology 99(2), 260-266. 16. Åkesson A, Berglund M, Schütz A, Bjellerup P, Bremme K, Vahter M. (2002) Cadmium exposure in pregnancy and lactation in relation to iron status. Am J Public Health 92, 284-287.

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17. Alexandrie A-K, Rannug A, Juronen E, Tasa G, Warholm M. Detetection and characterization of a novel functional polymorphism in the GSTT1 gene. Pharmacogenetics (2002) 12, 613-619.

18. Benhamou, S., Lee, W.J., Alexandrie, A.K., Boffetta, P., Bouchardy, C., Butkiewicz, D., Brockmoller, J., Clapper, M.L., Daly, A., Dolzan, V., Ford, J., Gaspari, L., Haugen, A., Hirvonen, A., Husgafvel-Pursiainen, K., Ingelman-Sundberg, M., Kalina, I., Kihara, M., Kremers, P., Le Marchand, L., London, S.J., Nazar-Stewart, V., Onon-Kihara, M., Rannug, A., Romkes, M., Ryberg, D., Seidegard, J., Shields, P., Strange, R.C., Stucker, I., To-Figueras, J., Brennan, P. and Taioli, E. (2002) Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk. Carcinogenesis, 23, 1343-50.

19. Huang, P., Ceccatelli, S., Ahlbom, E., and Rannug, A. (2002) A study on circadian mRNA rhythms of CYP1A1, AHR, ARNT, AA-NAT, and PER2 in rat pituitary and liver. Environmental Toxicology and Pharmacology, 11, 119-126.

20. Huang, P., Ceccatelli, S., Håkansson, H., Grandison, L. and Rannug, A. (2002) Constitutive and TCDD-induced expression of Ah receptor-responsive genes in the pituitary. Neurotoxicology, 129, 1-11.

21. Ernstgård L, Gullstrand E, Löf A, Johanson G. Are women more sensitive than men to 2-propanol and m-xylene vapors? Occup Environ Med 59 (2002) 759-767.

22. Fustinoni S, Soleo L, Warholm M, Begemann P, Rannug A, Neumann H-G, Swenberg JA, Vimercati L, Foà V, Colombi A. Influence of metabolic genotypes on biomarkers of exposure to 1,3-butadiene. Cancer Epidem Biomark Prev (2002) 11, 1082-1090.

23. Jonsson F, Johanson G. Physiologically based modeling of the inhalation kinetics of styrene in humans using a bayesian population approach. Toxicol Appl Pharmacol 179 (2002) 35-49.

24. Kuljukka-Rabb, T., Nylund, L., Vaaranrinta, R., Savela, K., Muatnen, P., Veidebaum, T., Sorsa, M., Rannug, A., Peltonen, K. (2002) The effect of relevant genotypes on PAH exposure-related biomarkers. Journal of Exposure Analysis and Environmental Epidemiology, 12, 81-91.

25. Shibata E, Löf A, Ernstgård L, Gullstrand E, Sigvardsson K, and Johanson G. (2002) Changes in n-hexane toxicokinetics due to co-exposure to methyl ethyl ketone (MEK) in volunteers. Int Arch Occup Environ Health 75 (2002) 399-405.

26. Sjögren B, Fossum T, Lindh T, Weiner J. Welding and ischemic heart disease. Int J Occup Environ Health 2002, 8: 309-311.

27. Sjögren B, Gunnare S, Sandler H. Inhalation of decomposed freon and myocardial infarction. Scand J Work Environ Health 2002; 28: 205-207.

28. Sjögren B, Knutsson A, Bergström H, Fellenius E, Fernström B, Isling D, Söderholm M. Fibrinogen concentrations in aluminium smelter workers. C Eur J Occup Environ Med 2002; 8: 49-54.

29. Tuominen R, Baranczewski P, Warholm M, Hagmar L, Möller L, Rannug A. Susceptibility factors and DNA adducts in peripheral blood mononuclear cells of aluminum smelter workers exposed to polycyclic aromatic hydrocarbons. Arch Toxicol (2002) 76, 178-186. 30. Büchert A, Cederberg T, Dyke P, Fiedler H, Fürst P, Hanberg A, Hosseinpour J, Hutzinger O, Kuenen JG, Malish R, Needham LL, Olie K, Päpke O, Rivera Aranda J, Thanner G, Umlauf G, Vartiainen T, van Holst C (2001): ESF Workshop. Dioxin Contamination in Food. Environ Sci & Pollut Res, 8, 84-88. 31. Chu I, LeCavalier P, Håkansson H, Yagminas A, Valli VE, Poon P, Feeley M (2001): Mixture effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and polychlorinated biphenyl congeners in rats. Chemosphere, 43, 807-814. 32. Fletcher N, Hanberg A, Håkansson H (2001): Hepatic vitamin A depletion is a sensitive marker of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in the guinea pig, rat, mouse and hamster. Toxicol Sci, 62, 166-175. 33. Hallgren S, Sinjari T, Håkansson H, Darnerud PO (2001): Effects of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) on thyroid hormone and vitamin A levels in rats and mice. Arch Toxicol, 75, 200-208. 34. Lind PM, Lind L, Larsson S, Örberg J (2001): Torsional testing and peripheral quantitative computed tomography (pQCT) in rat humerus. Bone, 29, 265-270.

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35. Rudén C (2001): The use and evaluation of primary data in 29 trichloroethylene carcinogen risk assessments. Reg Toxicol Pharmacol, 34, 3-16. 36. Rudén C (2001): Interpretations of primary carcinogenicity data in 29 trichoroethylene risk assessments. Toxicology, 169, 209-225. 37. Wennborg H, Bodin L, Vainio H, Axelsson G (2001): Solvent use and time to pregnancy among femal personnel in biomedical laboratories in Sweden. Occup Environ Med 58, 225-231. 38. Öberg M, Andersson PL, Johansson N, Tysklind M, Håkansson H (2001) Multivariate modelling of polychlorinated Biphenyl-induced CYP1A activity in the MH1C1 rat hepatoma cell line. ATLA 29, 1-5. 39. Giménez-Llort L, Ahlbom E, Daré E, Vahter M, Ögren S, and Ceccatelli S. (2001) Prenatal exposure to methylmercury changes dopamine-modulated motor activity during early ontogeny: age and gender-dependent effects. Environ Toxicol Pharmacol 9(3), 61-70. 40. Kull F, Ohlson E, Lind B, Haeggström JZ. (2001) Saccharomyces cerevisiae leukotriene A4 hydrolase: Formation of leukotriene B4 and identification of catalytic residues. Biochemistry 40, 12695-12703. 41. Sandborgh-Englund G, Ask K, Belfrage E, Ekstrand J (2001) Mercury exposure in utero and during infancy. J Toxicol Environ Health 63, 317-320. 42. Vahter M and Concha G (2001) Role of metabolism in arsenic toxicity. Pharmacol Toxicol 89, 1-5. 43. Ask K, Åkesson A, Berglund M, Vahter M. (2002) Inorganic mercury and methylmercury in placentas of Swedish women. Environ Health Perspect 110(5), 523-526. 44. Lu J, Jin T, Nordberg G and Nordberg M. (2001) Metallothionein gene expression in peripheral lymphocytes from cadmium exposed workers. Cell Stress and Chaperones 6(2), 97-104. 45. Vahter M, Berglund M, Åkesson A, Lidén C. (2002) Metals and women´s health. Environ Res 88, 145-155. 46. Åkesson A, Bjellerup P, Berglund M, Bremme K, Vahter M. (2002) Soluble transferrin receptor: longitudinal assessment from pregnancy to postlactation. Obstetrics & Gynecology 99(2), 260-266. 47. Åkesson A, Berglund M, Schütz A, Bjellerup P, Bremme K, Vahter M. (2002) Cadmium exposure in pregnancy and lactation in relation to iron status. Am J Public Health 92(2), 284-287. 48. Sjögren B. (2001) Air pollution, inflammation and cerebrovascular disease A hypothesis. C Eur J Occup Environ Med 7, 186-194. 49. Garte, S., Gaspari, L., Alexandrie, A. K., Ambrosone, C., Autrup, H., Autrup, J. L., Baranova, H., Bathum, L., Benhamou, S., Boffetta, P., Bouchardy, C., Breskvar, K., Brockmoller, J., Cascorbi, I., Clapper, M. L., Coutelle, C., Daly, A., Dell'Omo, M., Dolzan, V., Dresler, C. M., Fryer, A., Haugen, A., Hein, D. W., Hildesheim, A., Hirvonen, A., Hsieh, L. L., Ingelman-Sundberg, M., Kalina, I., Kang, D., Kihara, M., Kiyohara, C., Kremers, P., Lazarus, P., Le Marchand, L., Lechner, M. C., van Lieshout, E. M., London, S., Manni, J. J., Maugard, C. M., Morita, S., Nazar-Stewart, V., Noda, K., Oda, Y., Parl, F. F., Pastorelli, R., Persson, I., Peters, W. H., Rannug, A., Rebbeck, T., Risch, A., Roelandt, L., Romkes, M., Ryberg, D., Salagovic, J., Schoket, B., Seidegard, J., Shields, P. G., Sim, E., Sinnet, D., Strange, R. C., Stucker, I., Sugimura, H., To-Figueras, J., Vineis, P., Yu, M. C., and Taioli, E. (2001). Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol Biomarkers Prev 10, 1239-48.

50. Geijersstam, E., Sandborgh-Englund, G., Jonsson, F., and Ekstrand, J. (2001). Mercury uptake and kinetics after ingestion of dental amalgam. J Dent Res 80, 1793-1796. 51. Iregren, A., Sjögren, B., Gustavsson, K., Hagman, M., Nylén, L., Frech, W., Andersson, M., Ljunggren, K. G., and Wennberg, A. (2001). Effects on the nervous system in different groups of workers exposed to aluminium. Occup Environ Med 58, 453-460. 52. Jonsson, F., Bois, F., and Johanson, G. (2001). Assessing the reliability of PBPK models using data from methyl chloride-exposed, non-conjugating human subjects. Arch Toxicol 75, 189-199.

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53. Jonsson, F., Bois, F., and Johanson, G. (2001). Physiologically based pharmacokinetic modeling of inhalation exposure of human to dichloromethane during moderate to heavy exercise. Toxicol Sic 59, 209-218. 54. Jonsson, F., and Johanson, G. (2001). A Bayesian analysis of the influence of GSTT1 polymorphism on tne cancer risk estimate for dichloromethane. Toxicol Appl Pharmacol 174, 99-112. 55. Jonsson, F., and Johanson, G. (2001). Bayesian estimation of variability in adipose tissue blood flow in man by physiologically based pharmacokinetic modeling of inhalation exposure to toluene. Toxicology 157, 177-193. 56. Langworth, S., Anundi, H., Friis, L., Johanson, G., Lind, M.-L., Söderman, E., and Åkesson, B. (2001). Acute health effects common during graffiti removal. Int Arch occup Environ Health 74, 213-218. 57. Seeley, M., Tonner-Navarro, L., Beck, B., Deskin, R., feron, V., Johanson, G., and Bolt, H. (2001). Procedures for health risk assessment in Europe. Regul Toxicol Pharmacol 34, 153-169. 58. Warholm, M., Karlsson, Å., Tuominen, R., and Rannug, A. (2001). Determination of interindividual variation in glutathione transferase P1 mRNA expression and enzyme activity in human peripheral blood cells. Chem Biol Interact 133, 102-105. 59. Öberg, M., Wei, Y.-D., Rannug, A., and Håkansson, H. (2001). Influence of light on the CYP1A1 activity in rat hepatoma cells. Organohalogen Compounds 53, 408-410. 60. Fattore E, Trossvik C, Håkansson H (2000): Relative potency values derived from hepatic vitamin A reduction i male and female Sprague-Dawley rats following subchronic dietary exposure to individual polychlorinated dibenzo-p-dioxin and dibenzofuran congeners, and a mixture thereof. Toxicol Appl Pharmacol, 165, 184-194. 61. Haag-Grönlund M, Conolly R, Scheu G, Wärngård L, Fransson-Steen R (2000): Analysis of rat liver foci growth with a quantitative two-cell model after treatment with 2,4,5,3’,4’-pentachlorobiphenyl. Toxicol Sci 57, 32-42. 62. Huang P, Rannug A, Ahlbom E, Håkansson H, Ceccatelli S (2000): Effect of TCDD on the expression of CYP1A1, AHR and ARNT in rat brain and pituitary. Toxicol Appl Pharmacol, 169, 159-167. 63. Kelley SK, Nilsson CB, Green JB, H�kansson H, Green MH (2000): Mobilization of vitamin A stores in rats after administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin: a kinetic analysis. Toxicol Sci, 55, 478-484. 64. Lind P M, Larsson S, Oxlund H, Håkansson H, Nyberg K, Eklund T, Örberg J (2000): Change of bone tissue composition and impaired bone strength in rats exposed to 3,3´, 4,4´,5-pentachloro-biphenyl (PCB126). Toxicology, 150:43-53. B, O 65. Lind P M, Larsson S, Johansson S, Melhus H, Wikström M, Linde Ö, Örberg J (2000): Bone tissue composition, dimensions and strength in female rats given increased dietary level of vitamin A or exposed to 3,3´, 4,4´,5-pentachlorobiphenyl (PCB126) alone or in combination with vitamin C. Toxicology, 151:11-23 66. Magnusson K, Sandström M, Ståhlberg M, Larsson M, Flygare J, Hellgren D, Wiman K, Ljungquist S (2000): p53 splice acceptor site mutation and increased HsRAD51 protein expression in Bloom’s syndrome GM1492 fibroblasts. Gene 246:247-254. 67. Nilsson CB, Hoegberg P, Trossvik C, Azais-Braesco V, Blaner WS, Fex G, Harrison EH, Nau H, Schmidt C, van Bennekum AM, Håkansson H (2000): 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) increases serum and kidney retinoic acid levels and kidney retinol esterification in the rat Toxicol Appl Pharmacol, 169, 121-131. 68. Viluksela M, Bager Y, Tuomisto JT, Scheu G, Unkila M, Pohjanvirta R, Flodström S, Kosma VM, Mäki-Paakkanen J, Klimm C, Schramm KW, Vartiainen T, Wärngård L, Tuomisto J (2000): Liver tumor-promoting activity of 2,3,7,8-tetrachlodibenzo-p-dioxin (TCDD) in TCDD-sensitive and TCDD-resistant rat strains. Cancer Res 60, 6911-20. 69. Wennborg H, Bodin L, Axelsson G, Vainio H. (2000): Pregnancy outcome for female personnel in Swedish biomedical research laboratories J Occup Environ Med, 42, 438-446. 70. Wicklund G A, Michaelsson K, Lind P M, Wolk A, Aune M, Atuma S, Darnerud P O, Mallmin H (2000): Organochlorines and bone mineral density in swedish men from the general population. Osteoporos Int 11: 1036-42. 71. Berglund M, Åkesson A, Bjellerup P, Vahter M (2000) Metal-bone interactions. Toxicology Letters 112-113, 219-225.

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72. Björkman L, Vahter M, Pedersen NL (2000) Both the environment and genes are important for concentrations of cadmium and lead in blood. Environ Health Perspect 108(8), 719-722. 73. Osman K, Åkesson A, Berglund M, Bremme K, Schütz A, Ask K, Vahter M (2000) Toxic and essential elements in placentas of Swedish women. Clin Biochem 33(2), 131-138. 74. Osman K and Vahter M (2000) Health effects of environmental lead exposure in children. Medycynie Srodowiskowej 3(2), 7-14. 75. Vahter M (2000) Genetic polymorphism in the biotransformation of inorganic arsenic and its role in toxicity. Toxicology Letters Vol. 112-113, 209-217. 76. Vahter M, Concha G, Nermell B (2000) Factors influencing arsenic methylation in humans. J Trace Elem Exp Med. 13, 173-184. 77. Vahter M, Åkesson A, Lind B, Björs U, Schütz A, Berglund M (2000) Longitudinal study of methylmercury and inorganic mercury in blood and urine of pregnant and lactating women, as well as in umbilical cord blood. Environ Res, 84, 186-194. 78. Åkesson A (2000) Cadmium exposure and iron status. Scandinavian Journal of Nutrition 44, 166-167. 79. Åkesson A, Stål P, Vahter M (2000) Phlebotomy increases cadmium uptake in hemochromatosis. Environ Health Perspect 108(4), 289-291. 80. Nordberg M. (2000) Trace Elements and Metallothionein Related to Geo-Environment Journal Trace Elements in Experimental Medicine 13, 97-104 81. Nordberg M, Winblad B., Fratiglioni L., and Basun H. (2000) Lead Concentrations in Elderly Urban People Related to Blood pressure and Mental Performance: Results From A Population Based Study. American Journal of Industrial Medicine 38: 290-294 82. Nordberg GF, Jin T., Leffler P., Svensson M., Zhou T. and Nordberg M. (2000) Metallothioneins and Diseases With special reference to cadmium poisoning. Analusis 28, 5, 396-400. 83. Nordberg M. and Nordberg GF. (2000) Toxicological Aspects of Metallothionein, Cellular and Molecular Biology 46 (2) 451-463. 84. Nordberg M, Winblad B and Basun H (2000) Cadmium concentration in Blood in An Elderly urban Population BioMetals 13, 311-317 85. Ahmadi, A., Fredrikson, M., Jerregard, H., Akerback, A., Fall, P. A., Rannug, A., Axelson, O., and Soderkvis T, R. Sjögren B. Drabbas svetsare oftare av lunginflammation och hjärtinfarkt? Svetsen 2002; 61: 24-25. T, R. Sjögren B. Drabbas svetsare oftare av lunginflammation och hjärtinfarkt? Svetsen 2002; 61: 24-25.t, P. (2000). GSTM1 and mEPHX polymorphisms in Parkinson's disease and age of onset [In Process Citation]. Biochem Biophys Res Commun 269, 676-80.

86. Alexandrie, A. K., Warholm, M., Carstensen, U., Axmon, A., Hagmar, L., Levin, J. O., Ostman, C., and Rannug, A. (2000). CYP1A1 and GSTM1 polymorphisms affect urinary 1-hydroxypyrene levels after PAH exposure. Carcinogenesis 21, 669-676. 87. Anundi, H., Langworth, S., Johanson, G., Lind, M.-L., Åkesson, B., Friis, L., N, I., Söderman, E., Jönsson, B. A. G., and Edling, C. (2000). Air and biological monitoring of solvent exposure during graffiti removal. Int Arch Occup Environ Health 73, 561-569. 88. Huang, P., Rannug A., Ahlbom E., Håkansson H. and Ceccatelli S. (2000) Effect of TCDD on the expression of CYP1A1, AHR and ARNT in rat brain and pituitary. Toxicol Appl Pharmacol., 169, 159-167. 89. Johanson, G., Ernstgård, L., Gullstrand, E., Löf, A., Osterman-Golkar, S., Williams, C., and Sumner, S. (2000). Styrene oxide in blood, hemoglobin adducts, and urinary metabolites in human volunteers exposed to 13C8-styrene vapors. Toxicol Appl Pharmacol 168, 36-49.

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90. Löf, A., Rannug, A., and Warholm, M. (2000). Glutathione transferase T1 phenotype affects the toxicokinetics of inhaled methyl chloride in human volunteers. Pharmacogenetics 10, 645-653. 91. Nihlén, A., and Droz, P.-O. (2000). Toxicokinetic modelling of methyl formate exposure and implications for biological monitoring. Int Arch Occup Environ health 73, 479-487. 92. Sjögren, B. (2000). Non-neoplastic mortality of euopean workers who produce man made vitreous fibres. Letter to the editor. Occup Environ Med 57, 284. 93. Wei, Y.-D., Bergander, L., Rannug, U., and Rannug, A. (2000). Regulation of CYP1A1 transcription va the metabolism of the tryptophan-derived 6-formylindolo (3,2-b) carbazole. Arch Biochem Biophys 383, 99-107.

Reviews Boström C-E, Gerde P, Hanberg A, Jernström B, Johansson C, Kyrklund T, Rannung A, Törnqvist M, Victorin K, Westerholm R (2002): Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air. Environmental Health Perspectives 110 (suppl 3), 451-489. Håkansson H, Johansson N (2002): In Memoriam. Ulf G Ahlborg. Pharmacol Toxicol, 91,218. Nilsson CB, Håkansson H (2002): The retinoid signaling system – a target in dioxin toxicity. Crit Rev Tox, 32, 211-232. Vahter M, Berglund M, Åkesson A, Lidén C. (2002) Metals and women´s health. Environ Res 88, 145-155.

T, R Bostrom, C.E., Gerde, P., Hanberg, A., Jernstrom, B., Johansson, C., Kyrklund, T., Rannug, A., Tornqvist, M., Victorin, K. and Westerholm, R. (2002) Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air. Environ Health Perspect, 110 Suppl 3, 451-88.

Goyer RA, Cantor KP, Eaton DL, Henderson RF, Kosnett MJ, Ryan LM, Thompson KM, Vahter ME, Walker BJr. (2001) Arsenic in drinking water: 2001 update. Subcommittee on Arsenic in Drinking Water, National Research Council. National Academy of Sciences. National Academy Press, Washington D.C.

Lee, W.J., Brennan, P., Boffetta, P., London, S.J., Benhamou, S., Rannug, A., To-Figueras, J., Ingelman-Sundberg, M., Shields, P., Gaspari, L. and Taioli, E. (2002) Microsomal epoxide hydrolase polymorphisms and lung cancer risk: a quantitative review. Biomarkers, 7, 230-41.

Sjögren, B. (2001). Ta hänsyn tilll influensavaccinering vid studier av hjärtsjukdom. In Läkartidningen, Vol. 98, p. 1717.

Sjögren, B. (2001). Lung cancer among industrial sand workers exposed to crystalline silica. Letter to the editor. Am J Epidemiol 154, 785.

Abernathy C, Chakraborti D, Edmonds JS, Gibb, H, Hoet P, Hopenhayn-Rich C, Howe PD, Järup L, Meharg AA, Moore MR, Ng JC, Nishikawa A, Pyy, L, Sim M, Stauber J, Vahter M (2001) IPCS. Environmental Health Criteria 224. Arsenic and Arsenic Compounds. World Health Organization, 521 pp.

Johanson, G. (2000). Toxicity review of ethylene glycol monomethyl ether its acetate ester. Crit Rev Toxicol 30, 307-345.

Prasad AS and Nordberg M (2001) A special Issue on Landmark Articles , Introduction Journal Trace Elements in Experimental Medicine 14, 100 Prasad AS and Nordberg M (2001) (editors) A special Issue on Landmark Articles , Introduction Journal Trace Elements in Experimental Medicine 14:101-273 Skrifter i icke refereegranskade tidskrifter Lind PM, Milnes MR, Lundberg R, Guilette R, Örberg J (2002): Bone density in female juvenile American Alligators from a pesticide polluted lake (Lake Apopka). Organohalogen compounds 56, 45-47.

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Stern N, Lind M, Öberg M, Jensen S, Håkansson H (2002): Effects of subchronic exposure to fractions of Bealtic Herring oil on metaphyseal bone of rat femur. Organohalogen compounds, 59, 167-170. T, R. Sjögren B. Drabbas svetsare oftare av lunginflammation och hjärtinfarkt? Svetsen 2002; 61: 24-25. Fattore E, Filipsson A, Hanberg A, Bergendorff A, Håkansson H (2001): Toxicity of a technical mixture of polybrominated diphenyl ethers following 28 days of oral exposure in male and female rats. Organohalogen Compounds, 53, 357-360. Hoegberg P, Schmidt C, Nilsson C, Trossvik C, Ghyselinck N, Chambon P, Cenijn P, Slottje P, Schuur G, Brouwer A, Nau H, Håkansson H (2001): Studies of the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the retinoid system using retinoid pathway knockout mice. Organohalogen Compounds, 53, 117-120. Johansson N, Hanberg A, Bergek S, Tysklind M (2001): PCB in sealants is influencing the levels in indoor air. Organohalogen Compounds, 52, 436-440. Stern N, Öberg M, Casabona H, Trossvik C, Manzoor E, Johansson N, Lind M, Blomgren K, Jensen S, Haglund P, Wesén C, Örberg J, Feinstein R, Johansson A, Chu I, Poon R, Yagminas A, Brouwer A, Jones B, Håkansson H (2001): Subchronic toxicity of baltic herring oil and its fractions in the rat. Organohalogen compounds, 53, 271-274. Öberg M, Wei Y, Rannug A, Håkansson H (2001): Influence of light on the CYP1A1 activity in rat hepatoma cells. Organohalogen Compounds, 53, 408-410.

Jonsson, F. (2001). Physiological based pharmacokinetic modeling in risk assessment. Development of Bayesian population methods. Pharm D thesis. Arbete och Hälsa 6.

Sumner, S. C. J., Cruzan, G., Johanson, G., Ghanayem, I., and Fennell, (2001). Styrene metabolism in rats, mice, and humans. CIIT Activites 21, 1-15.

Wei, Y. D. (2001). Tryptophan photoproducts: Regulation of CYP1A1 transcription and modulation of cell growth. In Department of Genetic and Cellular Toxicology, p. 58. Stockholm University, Stockholm. Chu I, Nakai J, Yagminas A, Poon R, Valli T, Håkansson H, Bergman Å (2000): Toxicity of 2,3,3’,4,4’,5-hexachlorobiphenyl (PCB 156) in rats. Organohalogen compounds, 49, 185-188. Glynn AW, Michaelsson K, Lind PM, Aune M, Autuma S, Darnerud PO, Wolk A, Mallmin H (2000): The influence of PCB an chlorinated pesticides on bone mineral density in men. Organohoalogen compounds, 48, 191-194. Johansson N, Hanberg A (2000): Report from a Nordic meeting on the 1998 WHO consultation on ssessment of the health risks of dioxin; re-evaluation of the tolerable daily intake (TDI), Organohalogen Compounds 48, 252-255. McGuire J, Andersson P, Wollberg AR, Hanberg A, Poellinger L (2000): Involvement of the Ah receptor in alterations in immune system development, Organohalogen Compounds, 49, 82-83. Åkesson A (2000) Järnbrist under graviditet leder till ökad kadmiumbelastning. Magisterexamen i folkhälsovetenskap vid Institutet för miljömedicin, Karolinska Institutet.

Sjögren, B. (2000). Hälsoeffekter av luftföroreningar bildade vid svetsning och lödning. Svetsen 59, 25-26.

Edling C, Nordberg GF och Nordberg M redaktörer (2000). Lärobok Miljö-och hälsa-en lärobok i arbets-och miljömedicin Studentlitteratur 1-323 Edling C., Eriksson M., Nordberg G. och Nordberg M.(2000) Introduktion i Edling C., Nordberg G och Nordberg M. (redaktörer) 2000 Hälsa- och Miljö-en lärobok i arbets-och miljömedicin, Studentlitteratur 13-24

Nordberg G. och Nordberg M. (2000) Biologisk monitorering i Edling C., Nordberg G och Nordberg M. (redaktörer)Hälsa- och Miljö-en lärobok i arbets-och miljömedicin, Studentlitteratur 73-83

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Nordberg GF Lynoe N, Edling C, och Nordberg M (2000) Etik i Edling C., Nordberg G och Nordberg M. (redaktörer) Hälsa- och Miljö-en lärobok i arbets-och miljömedicin, Studentlitteratur, 284-293

Edling C., Eriksson M., Nordberg G. och Nordberg M. (2000) Appendix 1. Lagar förordningar, myndigheter mm i Edling C., Nordberg G och Nordberg M. (redaktörer) Hälsa- och Miljö-en lärobok i arbets-och miljömedicin, Studentlitteratur, 294-305

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Verksamhetsområde Toxikologi Originalpublikationer 1. Chandra, J., Mansson E., Gogvadze V., Kaufmann, S.H., Albertioni F. and Orrenius S., Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release Blood, 99, 655-663 (2002) 2. Ott, M., Robertson, J.D., Gogvadze, V., Zhivotovsky, B. and Orrenius, S., Cytochrome c release from mitochondria proceeds by a two-step process Proc.Natl Acad.Sci-USA, 99, 1259-1263 (2002) 3. Gogvadze G., Stridh, H., Orrenius, S and Cotgreave, I. Tributyltin causes cytochrome c release from isolated mitochondria by two discrete mechanisms Biochem. Biophys. Res. Commun., 292, 904-908 (2002) 4. Gleiss, B., Gogvadze, V., Orrenius, S. and Fadeel, B. Fas-triggered phosphatidylserine exposure is modulated by intracellular ATP FEBS Letters, 519, 153-158 (2002) 5. Kagan, V.E., Gleiss, B., Tyurina, Y.Y., Tyurin, V.A., Elenström-Magnusson, C., Liu, S-X., Serinkan, F.B., Arroyo, A., Chandra, J., Orrenius, S. and Fadeel, B A role for oxidative stress in apoptosis: Oxidation and externalization of phosphatidylserine is required for macrophage clearance of cells undergoing Fas-mediated apoptosis J. Immunol., 169, 487-499 (2002) 6. Robertson, J.D., Enoksson, M., Suomela , M., Zhivotovsky, B. and Orrenius, S. Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis J. Biol. Chem, 277, 29803-29809 (2002) 7. Sleeper, E., Tamm, C., Frisén, J., Zhivotovsky, B., Orrenius, S. and Ceccatelli, S. Cell death in adult neural stem cells Cell Death and Differentiation, 9, 1377-1378 (2002) 8. Joseph, B., Marchetti, P., Formstecher, P., Kroemer, G., Lewensohn, R., and Zhivotovsky, B. Mitochondrial dysfunction is an essential step for killing of non-small cell lung carcinomas resistant to conventional treatment. Oncogene,: 21, 65-77, (2002) 9. Thyrell, L., Erickson, S., Zhivotovsky, B., Pokrovskaya, K., Sangfelt, O., Castro, J., Einhorn, S., and Grander, D. Mechanism of interferon-alpha induced apoptosis in malignant cells. Oncogene, 21, 1251-1262, (2002) 10. Van Loo, G., Demol, H., van Gurp, M., Hoorelbeke, B., Schotte, P., Beyaert, R., Zhivotovsky, B., Gevaert, K., Declerq, W., Vandekerckhove, J., and Vandenabeele, P. A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid. Cell Death Differ. 9, 301-308, (2002) 11. Ekedahl, J., Joseph, B., Grigoriev, M.Y., Müller, M., Magnusson, C., Lewensohn, R., and Zhivotovsky, B. Expression of inhibitor of apoptosis proteins in small and non-small cell lung carcinoma cells. Exp. Cell Res., 279, 277-290, (2002) 12. Grigoriev, M.Y., Pozharissky, K.M., Hanson, K.P., Imyanitov, E.N., and Zhivotovsky, B. Expression of caspase-3 and –7 does not correlate with the extent of apoptosis in primary breast carcinomas. Cell Cycle, 1, 337-342, (2002) 13. Zhang X, Hu L, Fadeel B, Ernberg I. Apoptosis modulation of Epstein-Barr virus-encoded latent membrane protein 1 in the epithelial cell line HeLa is stimulus-dependent. Virology 304: 330-341, 2002 14. Arrroyo A, Modriansky M, Serinkan FB, Bello RI, Matsura T, Jiang J, Tyurin VA, Tyurina YY, Fadeel B, Kagan VE. NADPH oxidase-dependent oxidation and externalization of phosphatidylserine during apoptosis in Me2SO-differentiated HL-60 cells. Role in phagocytic clearance. J Biol Chem 277: 49965-49975, (2002) 15. Fonfría, E., Daré, E., Benelli, M., Suñol, C., Ceccatelli, S. Translocation of Apoptosis-Inducing Factor (AIF) in cerebellar granule cells exposed to methylmercury. European Journal Neuroscience, 16:1-5, (2002)

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16. Cotgreave IA, Gerdes RG, Schuppe-Koistinen I and Lind C (2002). S-glutathionylation of glyceraldehyde-3-phosphate dehydrogenase: Role of thiol oxidation and catalysis by glutaredoxin. Methods in Enzymology 348, 175-182. 17. Gogvadze V, Stridh H, Orrenius S and Cotgreave IA (2002). Tributyltin causes cytochrome c release from isolated mitochondria by two discrete mechanisms. Biochem. Biophys. Res. Commun., 292 (4), 904-908. 18. Cotgreave IA, Goldschmidt L, Tonkonogi M and Svensson M (2002). Differentiation-specific alterations to glutathione synthesis and hormonally-stimulated release from human skeletal muscle cells. FASEB J. 16, 435-437. 19. Svensson M, Cotgreave IA, Norman B, Sjöberg B, Ekblom Ö, Sjödin B, Ekblom B and Sjödin A (2002). Adaptive stress in glutathione and uric acid metabolism in man following controlled excercise and diet. Acta Physiological Scandinavica 176, 43-56. 20. Dandrea, T Bajak E, Daré E, Wärngård L and Cotgreave IA (2002). Protein S-gluathionylation correlates to selective stress gene expression and cytoprotection. Arch. Biochem. Biophys. 406, 241-252. 21. Lind C, Gerdes R, Hamnell Y, Schuppe-Koistinen I, Brockenhuus von Löwenhielm H and Cotgreave IA (2002). Identification of S-gluathionylated cellular proteins during oxidative stress and constitutive metabolism by affinity purification and proteomic analysis. Arch. Biochem. Biophys. 406, 229-240. 22. Wu, J., Gorman,A., Zhou, X., Ceccatelli, S. Chen, E. Involvement of caspase-3 in photoreceptor apoptosis induced by blue light exposure. Investigative Ophthalmology and Visual Science, 43:3349-3354, (2002) 23. Huang, P., Ceccatelli, S., Håkansson, H., Grandison, L., Rannug, A. Constitutive and TCDD-induced expression of Ah receptor-responsive genes in the pituitary. Neurotoxicology, 129: 1-11, (2002) 24. Götz, M., Koutsilieri, E., Riederer, P., Ceccatelli, S., Daré, E. Methylmercury induces neurite degeneration in primary culture of mouse dopaminergic mesencephalic cells. J Neural Transmission, 109: 597-605, (2002) 25. Huang, P., Ceccatelli, S., Rannug, A. A study on diurnal mRNA expression of CYP1A1, AHR, ARNT, and PER2 in rat pituitary and liver. Environmental Toxicology and Pharmacology, 11: 119-126, (2002) 26. Daré, E., Tofighi, R., Vettori, M.V., Momoi, T., Poli, D., Saido, T., Mutti, A., Ceccatelli, S. Styrene 7,8 induces caspase activation and regular DNA fragmentation in SK-N-MC neuronal cells. Brain Res, 933: 12-22, (2002) 27. Holm, P., Morgenstern, R. Hebert, H. (2002) "The 3-D structure of microsomal glutathione transferase 1 at 6 A resolution as determined by electron crystallography of p22121 crystals" Biochim. Biophys. Acta 1594, 276-285. 28. Iliadou A, Lichtenstein P, Morgenstern R, Forsberg L, Svensson R, de Faire U, Martin NG, Pedersen NL. (2002) "Repeated blood pressure measurements in a sample of Swedish twins: heritabilities and associations with polymorphisms in the renin-angiotensin-aldosterone system" J Hypertens. 20, 1543-50. 29. Tsoi C, Morgenstern R, Swedmark S. (2002) "Canine sulfotransferase SULT1A1: molecular cloning, expression, and characterization. Arch Biochem Biophys. 401, 125-33. 30. Svensson, R., Greno, C., Johansson, A.S., Mannervik, B. and Morgenstern, R. (2002) "Synthesis and characterization of 6-chloroacetyl-2-imethylaminonaphthalene as a fluorogenic substrate and a mechanistic probe for glutathione transferases" Anal Biochem 311, 171-8. 31. Jakobsson PJ, Thoren S, Morgenstern R, Samuelsson B (2002) “Characterization of microsomal, glutathione dependent prostaglandin E synthase” Adv Exp Med Biol 2002;507, 287-91.

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32. Vondracek, M., Weaver, D., Sarang, Z., Hedberg, J.J., Willey, J., Wärngård, L. and Grafström, R.C. Transcript profiling of enzymes involved in detoxification of xenobiotics and reactive oxygen in human normal and Simian virus 40 T antigen-immortalized oral keratinocytes. Int. J. Cancer, 99: 776-782, 2002 33. Dressler, D., Sarang, Z., Vondracek, M., Engelhart, K., Zsondy, Z., and Grafström, R.C. Expression of retinoid-related genes in normal, immortalized and malignant oral keratinocytes Int. J. Oncology, 20: 897-903, 2002 34. Gavrilovich Zgoda V, Arison B, Mkrtchian S, Ingelman-Sundberg M, Almira Correia M. Hemin-mediated restoration of allylisopropylacetamide-inactivated CYP2B1: a role for glutathione and GRP94 in the heme-protein assembly. Arch Biochem Biophys. 2002 Dec 1;408(1):58-68. O B 35. Ingelman-Sundberg M, Oscarson M. Human CYP allele database: submission criteria procedures and objectives. Methods Enzymol. 2002;357:28-36. 36. Simi A, Porsmyr-Palmertz M, Hjerten A, Ingelman-Sundberg M, Tindberg N. The neuroprotective agents chlomethiazole and SB203580 inhibit IL-1beta signalling but not its biosynthesis in rat cortical glial cells. J Neurochem. 2002 ;83:727-37. 37. Oscarson M, McLellan RA, Asp V, Ledesma M, Ruiz ML, Sinues B, Rautio A, Ingelman-Sundberg M. Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity. Hum Mutat. 2002 ;20:275-83. 38. Benhamou S, Lee WJ, Alexandrie AK, Boffetta P, Bouchardy C, Butkiewicz D, Brockmoller J, Clapper ML, Daly A, Dolzan V, Ford J, Gaspari L, Haugen A, Hirvonen A, Husgafvel-Pursiainen K, Ingelman-Sundberg M, Kalina I, Kihara M, Kremers P, Le Marchand L, London SJ, Nazar-Stewart V, Onon-Kihara M, Rannug A, Romkes M, Ryberg D, Seidegard J, Shields P, Strange RC, Stucker I, To-Figueras J, Brennan P, Taioli E. Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk. Carcinogenesis. 2002 ;23:1343-50. 39. Aklillu E, Herrlin K, Gustafsson LL, Bertilsson L, Ingelman-Sundberg M. Evidence for environmental influence on CYP2D6-catalysed debrisoquine hydroxylation as demonstrated by phenotyping and genotyping of Ethiopians living in Ethiopia or in Sweden. Pharmacogenetics. 2002;12:375-83. 40. Bardag-Gorce F, French BA, Li J, Riley NE, Yuan QX, Valinluck V, Fu P, Ingelman-Sundberg M, Yoon S, French SW. The importance of cycling of blood alcohol levels in the pathogenesis of experimental alcoholic liver disease in rats. Gastroenterology. 2002;123:325-35. 41. Lytton SD, Berg U, Nemeth A, Ingelman-Sundberg M. Autoantibodies against cytochrome P450s in sera of children treated with immunosuppressive drugs. Clin Exp Immunol. 2002;127:293-302. 42. Aklillu E, Oscarson M, Hidestrand M, Leidvik B, Otter C, Ingelman-Sundberg M. Functional analysis of six different polymorphic CYP1B1 enzyme variants found in an Ethiopian population. Mol Pharmacol. 2002;61:586-94. 43. Wennerholm A, Dandara C, Sayi J, Svensson JO, Abdi YA, Ingelman-Sundberg M, Bertilsson L, Hasler J, Gustafsson LL. The African-specific CYP2D617 allele encodes an enzyme with changed substrate specificity. Clin Pharmacol Ther. 2002;71:77-88. 44. Yasar U, Aklillu E, Canaparo R, Sandberg M, Sayi J, Roh HK, Wennerholm A. Analysis of CYP2C9*5 in Caucasian, Oriental and Black-African populations. Eur J Clin Pharmacol. 2002;58:555-8. 45. Sargsyan E, Baryshev M, Backlund M, Sharipo A, Mkrtchian S. Genomic organization and promoter characterization of the gene encoding a putative endoplasmic reticulum chaperone, ERp29. Gene. 2002 20;285:127-39. 46. Sargsyan E, Baryshev M, Szekely L, Sharipo A, Mkrtchian S. Identification of ERp29, an endoplasmic reticulum lumenal protein, as a new member of the thyroglobulin folding complex. J Biol Chem. 2002 10;277:17009-15.

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47. Thapar MM, Ashton M, Lindegardh N, Bergqvist Y, Nivelius S, Johansson I, Bjorkman A. Time-dependent pharmacokinetics and drug metabolism of atovaquone plus proguanil (Malarone) when taken as chemoprophylaxis. Eur J Clin Pharmacol. 2002;58:19-27. 48. Köhler, C., Gogvadze, V., Håkansson, A., Svanborg, C., Orrenius, S. and Zhivotovsky, B.: A folding variant of human α-lactalbumin induces mitochondrial permeability transition in isolated mitochondria Eur.J. Biochem. 268, 186-191 (2001) 49. Chandra, J., Zhivotovsky, B., Zaitsev S., Juntti-Berggren, L., Berggren. P-O and Orrenius S.: Role of apoptosis in pancreatic ß-cell death in diabetes Diabetes, 50, 44-47 (2001) 50. Chandra, J.,Yang, S-N., Köhler, M., Zaitsev, S., Juntti-Berggren, L., Berggren, P-O., Zhivotovksy, B. and Orrenius S.: Effects of serum from patients with type 1 diabetes on primary cerebellar granule cells Diabetes, 50, 77-81 (2001) 51. Samali, A., Robertson, J.,D., Peterson, E., Manero, F., van Zeijl, L., Paul, C., Cotgreave, I.A., Arrigo, A-P. and Orrenius S.: Hsp27 protects mitochondria of thermotolerant cells against apoptotic stimuli Cell Stress Chapron., 6, 49-58 (2001) 52. Gogvadze, V., Robertson, J. D., Zhivotovsky, B and Orrenius, S. Cytochrome c release occurs via Ca2+ - dependent and Ca2+ - independent mechanisms that are regulated by Bax J. Biol. Chem, 276, 19066-19071 (2001) 53. Concannon, C. G., Orrenius, S., and Samali, A. Hsp27 inhibits cytochrome c-mediated caspase activation by sequestering both pro-caspase-3 and cytochrome c Gene Expression, 6, 195-201 (2001) 54. Stridh, H., Cotgreave, I., Müller, M., Orrenius, S. and Gigliotti, D. Organotin-induced caspase activation and apoptosis in human peripheral blood lymphocytes Chem. Res. Toxicol, 14, 791-798 (2001) 55. Fadeel, B., Orrenius, S .and Henter, J-I., Familial hemophagocytic lymphohistiocytosis: too little cell death can seriously damage your health Leukemia and Lymphoma, 42, 13-20 (2001) 56. Hellström-Lindberg, E., Schmidt-Mende, J., Forsblom, A.-M., Christensen, B., Fadeel, B., and Zhivotovsky, B. Apoptosis in refractory anemia with ringed sideroblasts is initiated at the stem cell level and is associated with increased activation of caspases. Br. J. Haematol., 112, 714-726 (2001) 57. Mejer, A.E., Ekedahl, J., Joseph, B., Castro, J., Harms-Ringdahl, M., Zhivotovsky, B., and Lewensohn, R. High-LET radiation induces apoptosis in lymphoblastoid cell lines derived from ataxia-telangiectasia patients. Internat. J. Radiat. Biol., 77, 309-317 (2001) 58. Schmidt-Mende, J., Tehranchi, R., Forsblom, A.M., Joseph, B., Christensson, B., Fadeel, B., Zhivotovsky, B., and Hellström-Lindberg, E. Granulocyte-colony stimulating factor inhibits Fas-triggered apoptosis in bone marrow cells isolated from patients with refractory anemia with ringed sideroblasts. Leukemia, 15, 742-751 (2001) 59. Joseph, B., Ekedahl, J., Lewensohn, R., Marchetti, P., Formstecher, P., and Zhivotovsky, B. Defective caspase-3 relocalization in non small cell lung carcinoma. Oncogene, 20, 2877-2888 (2001) 60. Dare, E., Li, W., Zhivotovsky, B., Yuan, X., and Ceccatelli, S. Methylmercury and H2O2 provoke lysosomal damage in human astrocytoma D384 cells followed by apoptosis. Free Rad. Biol. Med., 30, 1347-1356 (2001) 61. Djerbi, M., Darreh-Shori, T., Zhivotovsky, B., and Grandien, A. Characterization of the human FLICE-inhibitory protein locus and comparison of the anti-apoptotic activity of four different FLIP isoforms. Scand. J. Immunol. 54, 180-189 (2001) 62. Denecker, G., Vercammen, D., Steemans, M., Vanden Berghe, T., Brouckaert, G., Van Loo, G., Zhivotovsky, B., Fiers, W., Grooten, J., Declercq, W., and Vandenabeele, P. Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria. Cell Death Differ. 8, 829-840 (2001)

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63. Ericson, K., Fadeel, B., Nilsson-Ardnor, S., Söderhäll, C., Samuelsson, A.C., Janka G., Schneider M., Gürgey, A., Yalman, N., Révèsz T, Egeler, M., Jahnukainen, K., Storm-Mathisen, I., Haraldsson, A., Poole, J., de Saint Basile, G., Nordenskjöld, M., Henter, J-I. Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis. Am. J. Hum. Genet. 68, 590-597 (2001) 64. Henter, J-I., Karlén, J., Bernstrand, C., Calming, U., Andersson, U., Fadeel, B. Successful treatment of Langerhans cell histiocytosis with etanercept. N. Engl. J. Med. 345, 1577-1578 (2001) 65. Daré, E., Gorman, A., Ahlbom, E., Götz, M., Momoi, T., Ceccatelli, S. Apoptotic morphology does not always require caspase activity in rat crebellar granule neurons. Neurotoxicity Res, 3, 501-514 (2001) 66. Castoldi, A., Coccini, T., Ceccatelli, S., Manzo, L. Neurotoxicity of methylmercury. Review of molecular effects and implications to human risk assessment. Brain Res Bull, 55, 197-203 (2001) 67. Ahlbom, E., Prins, G., Ceccatelli, S. In vitro treatment with testosterone protects cerebellar granule cells against oxidative stress via a receptor mediated mechanism. Brain Res, 892, 255-262 (2001) 68. Gimenez-Llort, L., Ahlbom, E., Daré, E., Vahter, M., Ögren, S-O., Ceccatelli, S. Prenatal exposure to methylmercury changes dopamine-modulated motor activity during early ontogeny: age and gender-dependent effects. Environ Toxicol Pharmacol., 9, 61-70 (2001) 69. Rechkoblit O, Krzeminsky J, Amin S, Jernström B, and Geacintov NE: Influence of bulky polynuclear carcinogen lesions in a TATA promoter sequence on TATA binding protein_DNA complex formation. Biochemistry, 40, 5622-5632, 2001. 70. Sundberg K, Dreij K, Berntsen S, Seidel A, and Jernström B: Expression of human glutathione transferases in V79 cells and the effect on DNA adduct-formation of diol epoxides derived from polycyclic aromatic hydrocarbons. Chem.-Biol. Interact., 133, 91-94, 2001. 71. Samali A, Robertson JD, Peterson E Manero F, Van Zeijl L, Paul C, Arrigo AP, Cotgreave IA and Orrenius S (2001). HSP27 protects mitochondria of thermotolerant cells against apoptotic stimuli. Cell Stress and Chaperones 6, 49-58. 72. Malmström J, Jonsson M, Cotgreave IA, Hammarström L, Sjödin M and Engman L (2001). The antioxidant profile of 2,3-Dihydrobenzo(b)furan-5-ol and its 1-thio, 1-seleno- and 1-telluro derivatives. J. Am. Chem. Soc., 123, 3434-3440. 73. Bäck M, Kumlin M, Cotgreave Ian and Dahlen SE (2001). An alternative pathway for metabolism of leukotriene D4: Effects on contraction to cysteinyl-leukotrienes in the guinea pig trachea. Br. J. Pharmacol., 133, 1134-1144. 74. Stridh H, Cotgreave IA, Muller M, Orrenius S and Gigliotti D (2001). Organotin-induced caspase activation and apoptosis in human peripheral blood lymphocytes. Chem. Res. Toxicol., 14, 791-798. 75. Morgenstern, R., Svensson, R., Bernat, B. and. Armstrong, R.N. (2001) “ Kinetic analysis of the slow ionization of glutathione by microsomal glutathione transferase MGST1 ” Biochemistry, 40, 3378-84. 76. Forsberg, L., de Faire U. and Morgenstern, R. (2001) "Oxidative stress, human genetic variation and disease" Arch. Biochem. Biophys. 389, 84-93. 77. Forsberg, L., Lyrenäs, L., de Faire U. and Morgenstern, R. (2001) " A common functional C-T substitution polymorphism in the promoter region of the human catalase gene influences transcription factor binding, reporter gene transcription and is correlated to blood catalase levels." Free Radical Biol. Med. 30, 500-5. 78. Bennet AM, Naslund TI, Morgenstern R, de Faire U. (2001) "Bioinformatic and experimental tools for identification of single-nucleotide polymorphisms in genes with a potential role for the development of the insulin resistance syndrome" J. Intern. Med. 249, 127-36

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79. Tsoi, C., Falany, C.N., Morgenstern, R., Swedmark, S. (2001) "Molecular Cloning, Expression, and Characterization of a Canine Sulfotransferase That Is a Human ST1B2 Ortholog" Arch. Biochem. Biophys. 390, 87-92. 80. Tsoi, C., Falany, C.N., Morgenstern, R., Swedmark, S. (2001) "Identification of a new subfamily of sulphotransferases: cloning and characterization of canine SULT1D1" Biochem J. 356, 891-7. 81. Svensson R, Pamedytyte V, Juodaityte J, Makuska R, Morgenstern R. (2001) "Characterisation of polymeric surfactants that are glutathione transferase mimics" Toxicology. 168, 251-8. 82. Vondracek, M., Zheng, X., Larsson, P., Baker, V., Mace, C., Pfeifer, A., Tjälve, H. and Grafström, R.C. Cytochrome P450 expression and related metabolism in human buccal mucosa Carcinogenesis, 22, 481-488, 2001 83. Hansson, A., Bloor, B. K., Haig, Y., Morgan, P.R. and Grafström R.C. Expression of keratins in normal, immortalized and malignant oral epithelia in organotypic culture Oral Oncol., 37, 19-30, 2001 84. Hedberg, J. J., Hansson, A., Nilsson, J.A., Höög J.-O., and Grafström, R.C. Uniform expression of alcohol dehydrogenase 3 (ADH3) in regenerated epithelia of normal, immortalized and malignant human oral keratinocytes. ATLA-Altern. Lab. Anim., 29, 1-9, 2001 85. Hedberg, J. J., Grafström, R. C., Vondracek, M., Sarang Z., Wärngård, L. and Höög, J.-O Microarray analysis of carbonyl-metabolizing enzymes in normal, immortalized and malignant oral keratinocytes. Cell. Mol. Life Sci., 58, 1719-1726, 2001 86. Crawford, E. L., Peters, G. J., Noordhuis P., Rots, M. G., Vondracek, M., Grafström, R. C., Lieuallen, K., Lennon, G., Zahorchak, R. J., Georgeson, M. J., Wali, A., Lechner, J.F., Fan, P.S., Kahaleh M. B., Khuder, S. A., Warner, K. A., Weaver, D. A. and Willey, J.C. Reproducible gene expression measurement among multiple laboratories obtained in a blinded study using standardized RT (StaRT)-PCR Mol. Diagnosis, 6, 217-225, 2001 87. Högberg J, Silins I, Finnberg N, Ståhl A and Stenius U. (2001) Attenuated p53 response to genotoxic stress in preneoplastic alterations in rat and mouse liver. Toxicologic Pathology, 29, 229-230. 88. Silins I, Finnberg N, Ståhl A, Högberg J and Stenius U. (2001) Reduced ATM kinase activity and an attenuated p53 response to DNA damage in carcinogen-induced preneoplastic hepatic lesions in the rat. Carcinogenesis, 22, 2023-2031. 89. Loriot M-A, Rebuissou S, Oscarson M, Cenée S, Miyamoto M, Ariyoshi N, Kamataki T, Hémon D, Beaune P, Stücker I: Genetic polymorphisms of cytochrome P450 2A6 in a case-control study on lung cancer in a French population. Pharmacogenetics, 2001, 11: 39-44. 90. Werlinder V, Backlund M, Zhukov A, Ingelman-Sundberg M: Transcriptional and posttranslational regulation of CYP1A1 by primaquine. J Pharm Exp Ther, 2001, 297: 206-214. 91. Rylander, T., Neve, E.P.A., Ingelman-Sundberg M. and Oscarson, M.: Identification and tissue distribution of the novel human cytochrome P450 2S1 (CYP2S1) Biochem Biophys Res Commun, 2001, 281: 529-535. 92. Westlind, A., Malmebo, S., Johansson, I., Otter, C, Andersson , T.B., Ingelman-Sundberg, M. and Oscarson, M.: Cloning and tissue distribution of a novel human cytochrome P450 of the CYP3A subfamily, CYP3A43. Biochem Biophys Res Commun, 2001, 281:1349-55. 93. Wennerholm, A., Johansson, I., Hidestrand, M., Bertilsson, L., Gustafsson, L.L. and Ingelman-Sundberg, M.: Characterization of a new CYP2D6 allele (CYP2D6*29) commonly present in a black Tanzanian population causing reduced catalytic activity, Pharmacogenetics, 2001, 11: 417-427. 94. Andersson, T.B., Sjöberg, H., Hoffman, K.-J., Boobis, A.R., Watts, P., Edwards RJ, Lake BG., Price R.J., Renwic, A.B., Gómez-Lechón, M.J., Castell, J.V., Ingelman-Sundberg, M., Hidestrand, M., Goldfarb, P., Lewis, D., Corcos, L., Guillouzo, A., Taavitsainen, P. and Pelkonen, O.: An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of Almokalant, Drug Met Disp, 2001, 29:712-20.

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95. Neve EP, Ingelman-Sundberg M.: Identification and characterization of a mitochondrial targeting signal in rat cytochrome P450 2E1 (CYP2E1). J Biol Chem. 2001, 276:11317-22. 96. Pitarque, M., von Richter, O., Oke, B., Berkkan, H, Oscarson, M and Ingelman-Sundberg M.: Identification of a Single Nucleotide Polymorphism in the TATA box of the CYP2A6 Gene: Impairment of its Promoter Activity. Biochem Biophys Res Commun, 2001, 284: 455-460. 97. Scordo, M.G., Aklillu, E., Yasar, U., Dahl, M.-L., Spina, E., and Ingelman-Sundberg, M.: Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a Black-African population. Br J Clin Pharm, 2001, 52: 447-450. 98. Pelkonen, O., Myllynen, P., Taavitsainen, P., Boobis, A.R., Watts, P., Lake, B.G., Price, R.J., Renwick, A.B., Gómez-Lechón, M.-J., Castell, J.V., Ingelman-Sundberg, M., Hidestrand, M., Guillouzo, A., Corcos, L., Goldfarb, P. S., Lewis, D.F.V.: Carbamazepine: a “blind” assessment of CYP-associated metabolism and interactions in human liver-derived in vitro systems. 2001, Xenobiotica, 31:321-343. 99. Yasar, Ü., Tybring, G., Hidestrand, M., Oscarson, M., Ingelman-Sundberg, M., Dahl, M.-L., Eliasson, E.: The role of CYP2C9 polymorphism in losartan oxidation. 2001, Drug Met Disp, 29: 1051-1056. 100. Liepinsh, E., Baryshev, M., Sharipo, A., Ingelman-Sundberg, M., Otting, G., Mkrtchian, S.: Thioredoxin fold as a homodimerization module in the putative chaperone ERp29: NMR structures of the domains and experimental model of the 54 kDa homodimer. Structure, 2001, 9: 457-471. 101. Hosseinpour F, Hidestrand M, Ingelman-Sundberg M, Wikvall K. The Importance of Residues in Substrate Recognition Site 3 for the Catalytic Function of CYP2D25 (Vitamin D 25-Hydroxylase). Biochem Biophys Res Commun. 2001; 288:1059-63. 102. Hidestrand M, Oscarson M, Salonen JS, Nyman L, Pelkonen O, Turpeinen M, Ingelman-Sundberg M. Cyp2b6 and cyp2c19 as the major enzymes responsible for the metabolism of selegiline, a drug used in the treatment of parkinson's disease, as revealed from experiments with recombinant enzymes. Drug Metab Dispos. 2001; 29:1480-4. 103. Ingelman-Sundberg M, Oscarson M, Daly AK, Garte S, Nebert DW. Human Cytochrome P-450 (CYP) Genes: A Web Page for the Nomenclature of Alleles. Cancer Epidemiol Biomarkers Prev. 2001; 10:1307-8. 104. Garte S, …. Ingelman-Sundberg M, … Persson I, … Vineis P, Yu MC, Taioli E. Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol Biomarkers Prev. 2001; 10:1239-48. 105. Hedberg JJ, Backlund M, Stromberg P, Lonn S, Dahl ML, Ingelman- Sundberg M, Hoog JO. Functional polymorphism in the alcohol dehydrogenase 3 (ADH3) promoter. Pharmacogenetics. 2001; 11:815-24. 106. Evans WE, Ingelman-Sundberg M. Resequencing the sulfotransferase SULT1 gene provides new insights, while illuminating challenges that lie ahead for pharmacogenomics. Pharmacogenetics. 2001; 11:745-6. 107. Ingelman-Sundberg M, Evans WE. Unravelling the functional genomics of the human CYP2D6 gene locus. Pharmacogenetics. 2001; 11:553-4. 108. Oscarson M: Genetic polymorphisms in the cytochrome P450 2A6 (CYP2A6) gene: Implications for interindividual differences in nicotine metabolism. Drug Met Disp, 2001, 29: 91-95. 109. Raucy JL, Ingelman-Sundberg M, Carpenter S, Rannug A, Rane A, Franklin M, Romkes M Drug metabolizing enzymes in lymphocytes, J Biochem Mol Toxicol 1999, 13: 223-226. 110. Gorman, A.M., Hirt,U.A., Orrenius, S and Ceccatelli S. Dexamethasone pre-treatment interferes with apoptotic death in glioma cells. Neuroscience, 96, 417 – 425 (2000) 111. Robertson, J.D., Orrenius, S. and Zhivotovsky, B Nuclear events in apoptosis J. Struct. Biol., 129, 346-358 (2000)

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112. Fadeel, B., Orrenius, S. and Zhivotovsky, B. The most unkindest cut of all: on the multiple roles of mammalian caspases Leukemia, 14, 1514-1525 (2000) 113. Chandra, J., Samali, A., Orrenius, S. Triggering and modulation of apoptosis by oxidative stress Free Radical Biology & Medicine, 29, 323-333 (2000) 114. Robertson, J.D., Gogvadze, V., Zhivotovsky, B., Orrenius, S.: Dinstinct pathways for stimulation of cytochrome c release by etoposide J.Biol.Chem, 275, 32438-32443 (2000) 115. Gorman, A.M., Ceccatelli, S. and Orrenius, S.: Role of mitochondria in neuronal apoptosis Dev. Neurosci, 22, 348-358 (2000). 116. Fadeel, B., Orrenius, S. and Zhivotovsky, B.: The potential role of apoptosis in human disease Med Principles Pract, 9, 151-163 (2000) 117. Cai, J., Wallace, D.C., Zhivotovsky, B., and Jones, D.P. Separation of cytochrome c-dependent caspase activation from thiol-disulfide redox change in cells lacking mitochondrial DNA. Free Rad. Biol. Med. , 29, 334-342 (2000) 118. Schmidt-Mende, J., Hellström-Lindberg, E., Joseph, B., and Zhivotovsky, B. Freezing induces artificial cleavage of apoptosis-related proteins in human bone marrow cells. J. Immunol. Methods, 245, 91-94 (2000) 119. Dare, E., Götz, M.E., Zhivotovsky, B., Manzo, L., and Ceccatelli, S. The antioxidants J811 and 17β-estradiol protect cerebellar granule cells from methylmercury-induced apoptotic cell death. J. Neurosci. Res., 62, 557-565 (2000) 120. Filonova, L.H., Bozhkov, P.V., Brukhin,V.B., Daniel, G., Zhivotovsky, B., and von Arnold, S. Two waves of programmed cell death occurs during formation and development of somatic embryos in the gymnosperm, Norway spruce. J. Cell Sci. 113, 4399-4411 (2000) 121. Joseph, B , Lewensohn, R., and Zhivotovsky, B. Role of apoptosis in the response of lung carcinomas to anti-cancer treatment. Ann. N.Y. Acad. Sci., 926, 204-216 (2000) 122. Ahlbom, E., Gogvadze, V., Chen, M., Celsi, G., Ceccatelli, S. Prenatal exposure to high levels of glucocorticoids increases the susceptibility of cerebellar granule cells to oxidative stress-induced cell death. Proc Natl Acad Sci, 97, 14726-14730 (2000) 123. Huang, P., Rannug, A., Ahlbom, E., Håkansson, H., Ceccatelli, S. Effect of TCDD on the expression of CP1A1, AHR and ARNT in rat brain and pituitary. Toxicol Appl Pharmacol., 169, 159-167 (2000) 124. Sundberg K, Townsend AJ, Seidel A and, Jernström B: Glutathione conjugation and DNA adduct formation of diol epoxides in V79 cells expressing human glutathione transferase P1-1 Polycyclic Aromatic Compounds, 21, 123-133, 2000. 125. Sundberg K, Jernström B, and Swedmark S: Studies on the differential inhibition of glutathione conjugate formation of (+)-anti-benzo[a]pyrene 7,8-dihydrodiol 9,10-epoxide and 1-chloro 2,4-dinitrobenzene in V79 Chinese hamster cells. Biochem. J., 349, 693-696, 2000 126. Stridh H, Gigliotti D, Orrenius S and Cotgreave IA (2000). The role of calcium in mitochondrial and post-mitochondrial events in TBT-induced T cell apoptosis. Biochem. Biophys. Res Comms. 266, 460-465. 127. Forsberg, L., Leeb, L., Thoren, S., Morgenstern, R and Jakobsson, P-J. (2000) “Human glutathione dependent prostaglandin E synthase: Gene structure and regulation” FEBS Letters, 471, 78-82. 128. Kelner, M.J., Bagnell, R.D., Montoya, M.A., Estes, L.A., Forsberg, L. and Morgenstern,. R. (2000) “Correct structural organization of the microsomal glutathione S-transferase gene (MGST1) on Chromosome 12p13.1-2 and demonstration of transcriptional regulation in response to oxidative stress” J. Biol. Chem. 275, 13000-13006.

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129. Nordström, T., Ronaghi, M., Forsberg, L., De Faire, U., Morgenstern, R and Nyren, P. (2000) “Direct analysis of single nucleotide polymorphism on PCR product by pyrosequencing” Biotechnology and Applied Biochemistry, 31, 107-112. 130. Jakobsson, P.-J., Morgenstern, R., Mancini, J., Ford-Hutchinson, A. and Persson, B. (2000) “Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG): a widespread protein family” A,. J. Respir. Crit. Care Med. 161, S20-4. 131. Forsberg, L., de Faire, U., Marklund, S. L., Andersson, P. M., Stegmayr, B. and Morgenstern, R. (2000) “Phenotype determination of a common pro-leu polymorphism in human glutathione peroxidase 1” Blood Cells, Molecules, and Disease 26, 423-426. 132. Svensson, R., Rinaldi, R., Swedmark, S. and Morgenstern, R. (2000) “Reactivity of cysteine-49 and its influence on the activation of microsomal glutathione transferase 1: evidence for subunit interaction” Biochemistry, 39, 15144-9. 133. Schmidt-Krey, I., Mitsuoka, K., Hirai, T., Murata, K., Cheng, Y., Fujiyoshi, Y., Morgenstern, R., and Hebert, H., (2000) “The three-dimensional map of microsomal glutathione transferase 1 at 6 Å resolution” EMBO J. 19, 6311-6. 134. Hedberg, J., Höög J.-O., Nilsson, J.A., Zheng, X., Elfwing, Å. and Grafström, R.C. Expression of alcohol dehydrogenase 3 in tissue and cultured cells from human oral mucosa Am. J. Pathol., 157, 1745-1755, 2000 135. van Gijssel HE, Stenius U, Mulder GJ and Meerman JHN. (2000) Lack of p53 protein expression in preneoplastic rat hepatocytes in vitro and p53 expression by N-acetoxy-acetylaminofluorene, X-ray-irradiation or a proteasome inhibitor. Eur J. Cancer, 36, 106-122. 136. Finnberg N, Stenius U and Högberg J. (2000) Tumor promoters modulate the p53 response to DNA damage in preneoplastic enzyme altered foci in rat liver; effects of diethylnitrosamine and phenobarbital. Toxicological Sciences, 54, 95-103. 137. Thullberg M, Welcker M, Bartkova J, Arnt Kjerulff A, Lukas J, Högberg J and Bartek J. (2000) Monoclonal antibody probes for p21waf1/cip1 and the INK4 family of cyklin-dependent kinase inhibitors. Hybridoma, 19, 63-72. 138. Järveläinen HA, Fang C, Ingelman-Sundberg M, Lukkari T, Sippel H, Lindros KO: Kupffer cell inactivation alleviates rat liver ethanol-induced steatosis and CYP2E1 induction but not inflammatory responses in rat liver, J Hepatol, 2000, 32: 900-910. 139. Simi A, Ingelman-Sundberg M, Tindberg N: Neuroprotective agent chlormethiazole attenuates c-fos, c-jun and AP-1 activation through inhibition of p38 MAP kinase, J Cereb Blood F Met, 2000, 20:1077-1088. 140. Longo V, Ingelman-Sundberg M, Amato G, Salvetti A, Gervasi PG: Effect of starvation and chlormethiazole on cytochrome P450s of rat nasal mucosa. Biochem Pharmacol 2000, 59:1425-1432. 141. Gouillon Z-Q, Lucas D, Li J, Hagbjork AL, French BA, Fu P, Ingelman-Sundberg M, Donohue JrTM, French SW: Inhibition of ethanol-induced liver disease in the intragastric feeding rat model by chlomethiazole, Proc Exp Soc Med, 2000, 224: 302-308. 142. Ingelman-Sundberg M, Daly AK, Oscarson M, Nebert DW: Human cytochrome P450 (CYP) genes: recommendations for the nomenclature of alleles. Pharmacogenetics, 2000, 10: 91-93. 143. Neve EPA, Ingelman-Sundberg M: Molecular basis for the transport of cytochrome P450 2E1 to the plasma membrane. 2000, J. Biol. Chem, 275:17130-17135. 144. McLellan RA, Oscarson M, Hidestrand M, Leidvik B, Jonsson E, Otter C, Ingelman-Sundberg M: Characterization and functional analysis of two common human cytochrome P450 1B1 variants, Arch Biochem Biophys, 2000, 378:175-181.

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145. Bylund J, Hidestrand M, Ingelman-Sundberg M, Oliw EH: CYP4F8 of human seminal vesicles is a prominent 19-hydorxylase of prostaglandin endoperoxides, J Biol Chem, 2000, 275: 1844-1849. 146. Badger TM, Hoog J-O, Svensson S, McGehee RE, Fang C, Ronis MJJ, Ingelman-Sundberg M: Cyclic expression of class I alcohol dehydrogenase in male rats treated with ethanol. Biochem Bioph Res Commun, 2000, 274: 684-688. 147. Bardag-Gorce F, Yuan QX, Li J, French BA, Fang C, Ingelman-Sundberg M, French SW. The effect of ethanol-induced cytochrome p4502E1 on the inhibition of proteasome activity by alcohol. Biochem Biophys Res Commun. 2000, 279: 23-29. 148. Tindberg, N., Porsmyr-Palmertz M. and Simi A. Contribution of MAP kinase pathways to the activation of ATF-2 in human neuroblastoma cells, Neurochemical Research, 2000, 25: 527-531. 149. Del Carratore, M.R., Mezzatesta, C., Hidestrand, M., Neve, P., Amato, G., Gervasi, P.G.: Cloning and expression of rat CYP2E1 in Saccharomyces cerevisiae: Detection of genotoxicity of N-alkylformamides. Environmental and Molecular Mutagenesis. 36: 97-104, 2000. 150. Reiter, L.T., Biehs, B., Ang, D., Oscarson, M., Bier, E.: Mis-expression of human cytochrome P450 (CYP2D6*17) in the Drosophila wing results in wing patterning defects. American J Hum Genet. 67: 900. 151. Persson, I., He, L., Fang, C., Normen, L., Rylander, R.: Influence of vegetables on the expression of GSTP1 in humans- a pilot intervention study. Cancer Causes Control., 2000, 11: 359-361. 152. Söderdahl T, Lundberg M, Enoksson M, Holmgren A, Ottersen OP, Bocsfoldi G and Ian A Cotgreave (2002). Visualisation of the compartmentalisation of glutathione and protein-glutathione mixed disulphides in cultured cells. FASEB J Express, 10.1096/fj.02-0259fje. 153. Oluwole S, Onabolu AO, Cotgreave IA, Rosling H, Persson A and Link H (2002). Low prevelance of ataxia polyneuropathy in a community with high exposure to cyanide from cassava foods. J. Neurol., 249, 1034-1040. Reviews Robertson, D.J and Orrenius, S. Role of mitochondria in toxic cell death Toxicology, 181-182, 491-496 (2002) Cotgreave IA, Gerdes R, Schuppe-Koistinen I and Lind C (2001). S-glutathionylation of glyceraldehyde-3-phosphate dehydrogenease: Role of thiol oxidation and catalysis by glutaredoxin. Methods in Enzymol., 348, 175-182. Ingelman-Sundberg, M.: Genetic susceptibility to adverse effects of drugs and environmental toxicants. The role of the CYP family of enzymes. Mutation research, 2001, 482: 11-19. Zhivotovsky, B. From the nematodes and mammals back to the pine tree: On the diversity and evolution of programmed cell death. Cell Death Differ., 9, 867-869, (2002) Rinaldi, R., Eliasson, E., Swedmark, S., Morgenstern, R. (2002) "Reactive intermediates and the dynamics of glutathione transferases" Drug Metab Dispos. 30, 1053-8. Ingelman-Sundberg M. Polymorphism of cytochrome P450 and xenobiotic toxicity. Toxicology. 2002 Dec 27;181-182:447-52. Lee WJ, Brennan P, Boffetta P, London SJ, Benhamou S, Rannug A, To-Figueras J, Ingelman-Sundberg M, Shields P, Gaspari L, Taioli E. Microsomal epoxide hydrolase polymorphisms and lung cancer risk: a quantitative review. Biomarkers. 2002 7(3):230-41. Högberg J and Stenius U. (2001) Letter to the editor: Lowered nuclear levels of p53 in preneoplastic hepatocytes. Hepatology, 33, 480-481.

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Ingelman-Sundberg M. Pharmacogenetics: an opportunity for a safer and more efficient pharmacotherapy. J Intern Med. 2001; 250:186-200. Alvan G, Bertilsson L, Dahl M-L, Ingelman-Sundberg M, Sjöqvist F: Moving toward genetic profiling in patient care: The scope and rationale of pharmacogenetic/ecogenetic investigations. Drug Met Disp, 2001, 29: 580-585. Ingelman-Sundberg M: Implications of polymorphic P450 dependent drug metabolism for drug development. Drug Met Disp, 2001, 29: 570-573. Ingelman-Sundberg, M.: Genetic variability in susceptibility and response to toxicants. Toxicology letters, 2001, 120:259-68. Robertson J.D., Orrenius, S. Molecular mechanisms of apoptosis induced by cytotoxic chemicals Crit.Rev.Toxicol., 30, 609-627 (2000) Chandra, J. and Orrenius, S.:Apoptosis and oxidative stress: Promotion, modulation and abrogation In: “Free Radicals in Chemistry, Biology and Medicine”, Yoshikawa, T., Toyokuni, S., Yamamoto, Y. and Naito, Y., eds OICA International (UK) Ltd, London, 285-298 (2000) Kass, G.,E.,N., Chow, S.,C. And Orrenius S.:Apoptosis trigered by free radicals: Role in Human Diseases In: Biomolecular Free Radical Toxicity: Causes and Prevention, Wiseman, H., Goldfarb, Ridgway, T.and Wiseman, A., Eds. John Wiley & Sons, Ltd, Chichester, 145 – 168 (2000) 7. Zhivotovsky, B and Orrenius, S.,Current concepts in cell death.In: “Current Protocols in Cell Biology”, Bonifacino, J.S., Dasso, M., Harford J.B., Lippincott-Schwartz, J., Yamada, K. M., eds. J. Wiley & Sons Inc., New York, 18.1.1-18.1.18 (2001) 8. Zhivotovsky, B and Orrenius, S., Assessment of apoptosis and necrosis by DNA fragmentation and morphological criteria. In: “Current Protocols in Cell Biology”, Bonifacino, J.S., Dasso, M., Harford J.B., Lippincott-Schwartz, J., Yamada, K. M., eds. J. Wiley & Sons Inc., New York, 18.3.1-18.3.23 (2001) Robertson, J.D., Chandra, J., Gogvadze, V. and Orrenius, S. Biological reactive intermediates and mechanisms of cell death In: “Biological Reactive Intermediates VI”, Dansette, P.M., Snyder,R., Delaforge,M., Gibson, G.G., Greim, H., Jollow,.D.J., Monks, T.J., Sipes, I.G. eds. Kluwer Academic / PlenumPublishers, New York, 1-10 (2001) Skrifter i icke refereegranskade tidskrifter. Robertson, J.D. and Orrenius, S. Biochemical signals that initiate apoptosis In: “Comprehensive Toxicology, Volume 14 Cellullar and Molecular Toxicology”, Vanden Heuvel, J.P., Perdew, G.H., Mattes, W.B., Greenlee, W.F. eds Elsevier Science B.V, Amsterdam 443-462 (2002) Robertson, J.D., Fadeel, B., Zhivotovsky, B. and Orrenius, S. “Centennial” Nobel Conference on apoptosis and human disease – Meeting Report Cell Death and Differentiation, 9, 468-475 (2002) Lendahl, U. and Orrenius, S. Sydney Brenner, Robert Horvitz och John Sulston, Nobelpristagare i fysiologi eller medicin år2002. Genetisk reglering av organutveckling och programmerad celldöd gav priset. Läkartidningen, 99, 4026-4032, (2002) Sundberg K, Dreij K, Seidel A, and Jernström B: Glutathione conjugation and DNA adduct formation of dibenzo[a,l]pyrene and benzo[a]pyrene diol epoxides in V79 cells stably expressing different human glutathione transferases. Chem Res Toxicol.,15, 170 - 179, 2002 Dreij K, Sundberg K, Johansson A-S, Nordling E, Seidel A., Persson B, Mannervik B, and Jernström B: Catalytic activites of human Alfa class glutathione transferases towards carcinogenic dibenzo[a,l]pyrene diol epoxides. Chem.Res. Toxicol., 15, 825 - 831, 2002 Sundberg K, Dreij K, Seidel A, and Jernström B: Glutathione conjugation of aromatic hydrocarbon diol epoxides by human glutathione transferases: Efficiency of conjugation in intact cells relative to purified enzymes. Polycyclic Aromatic Compounds, 22, 947 - 953, 2002

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Dreij K, Sundberg K, Johansson A-S, Seidel A., Mannervik B, and Jernström B: Inactivation carcinogenic diol epoxides of dibenzo[a,l]pyrene (dibenzo[def,p]chrysene) by human glutathione transferases diol epoxides. Polycyclic Aromatic Compounds 22, 947-953, 2002 Boström C-E, Gerde P, Hanberg A, Jernström B, Johansson C, Kyrklund T, Rannug A, Törnqvist M, Victorin K, and Westerholm R: Cancer risk assessment, indicators and guidelines for polycyclic aromatic hydrocarbons (PAH) in the ambient air. Environ Health Perspec., 110, suppl. 3, 451-488, 2002 Cotgreave IA (2002). Analytical developments in the assay of intra- and extracellular GSH homeostasis. Specific protein S-glutathionylation, cellular GSH and mixed disulphide compartmentalisation and interstitial GSH redox balance. In: Thiol metabolism and Rdox Regulation of Cellular Functions. A Pompela et al Eds., IOS press, pp 290-298. Grafström, R.C. Human oral epithelium In: Culture of Epithelial Cells, Second edition, (Freshney, I.R. and Freshney M.G., eds) John Wiley and Sons, Inc., New York, pp. 195-255, 2002 Hedberg, J.J., Höög J.-O. and Grafström R.C. Assessment of formaldehyde metabolizing enzymes in human oral mucosa and cultured oral keratinocytes indicate high capability for detoxification of formaldehyde In: Crucial Issues in Inhalation Research-Mechanistic, Clinical and Epidemiologic, (Heinrich U. and Mohr U., eds), INIS Monographs, Frauhofer IRB Verlag, Stuttgart pp. 103-115, 2002 Hansson, A., Vondracek, M. and Grafström R.C. Cultured human oral epithelium: modeling of early stages of tumor progression In: Oral Oncology, Vol. 8, (Varma A.K., Kowalski L.P. and Herter N., eds.), MacMillian India LTD, New Delhi, pp.131-133, 2002 Ingelman-Sundberg M: Cytochrome P450 2D6 (debrisoquine hydroxylase, CYP2D6), 2000, Encyclopædia of Molecular Medicine, John Wiley and Sons, 5: 1006-1008, 2002. Fadeel, B. Apoptosis – Emperor’s new clothes? Läkartidningen, 98, 4613 (2001) Vondracek, M., Hansson, A. and Grafström, R.C. Assessment of keratin expression and xenobiotic metabolism in cultured normal and transformed human oral keratinocytes. In: Animal Cell Technology: From Target to Market, (Lindner-Olsson, E., Chatzissavidou, N. and Lüllau, E., Eds), Kluwer Academic Publishers, Dordrecht, the Netherlands, pp. 143-148, 2001 Ingelman-Sundberg, M.: Genetic and environmental causes for interindividual variability in drug pharmacokinetics. ESTEVE Symposium, 2001, Fadeel, B., Henter J-I. och Orrenius S. Apoptosis is required for maintenance of homeostasis: familial hemophagocytic lymphohistiocytosis caused by too little cell death. Läkartidningen, 97,1395-1402 (2000) Henter, J-I., Samuelsson, A., Ericson, K., Nilsson-Ardnor, S., Elinder, G., Fadeel, B. Familial hemophagocytic lymphohistiocytosis: diagnosis, treatment and athophysiological mechanisms. Läkartidningen, 97, 1405-1408 (2000) Cotgreave IA, Morgenstern R, Jernström B and Orrenius S (2000). Current Molecular and Cellular Concepts in Toxicology. General and Applied Toxicology. volume 1, Ballantyne et al Eds., pp155-175, Macmillan. Ingelman-Sundberg M: Cytochrome P450 2D6 (debrisoquine hydroxylase, CYP2D6), 2000, Encyclopædia of Molecular Medicine, John Wiley and Sons, pp Oscarson, M. and Ingelman-Sundberg, M.: Genetically modified cells to assess drug metabolism in vitro., in press Atterwill, C., Purcell, W. and Goldfarb P. (Eds) in 'Approaches to High Throughput Screening'. Taylor and Francis, 2000, pp139-170.

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Verksamhetsområde fysiologi Originalpublikationer

1. Kumlin M, Dahlén B. The challenge procedure influences the extent of allergen-induced urinary excretion of leukotriene E4. Clin Exp Allergy 30; 585-589, 2000.

2. Bjermer LH, Ahlstedt S, and Braun J. Measurement of granulocyte derived markers in bronchoalveolar lavage fluid. Eur RespirRev 9: 126-134, 2000.

3. Younginger JW, Ahlstedt S, Eggleston PA, Homburger HA, Nelson HS, Ownby DR, Platts-Mills TAE, Sampson HA, Sicherer SH, Weinstein AM, Williams PB, Wood RA, and Zeiger RS. Quantitative IgE antibody assays in allergic diseases. J.Allergy Clin.Immunol. 105: 2000.

4. Grootendorst DC, Dahlén S-E, van den Bos JW, Duiverman EJ, Veselic-Charvat M, Vrijlandt EJLE, O’Sullivan S, Kumlin M, Sterk PJ, Roldaan BC: Benefits of high altitude allergen-avoidance in atopic adolescents with moderate to severe asthma, over and above treatment with high dose inhaled steroids. Clin Exp Allergy 31: 400-408, 2001.

5. Bäck M, Norel X, Walch L, Gascard J-P, De Montpreville V, Dahlén S-E, Brink C: Prostacyclin modulation of contractions of the human pulmonary artery by cysteinyl-leukotrienes. Eur J Pharmacol 401:389-395, 2000.

6. Bäck M, Norel X, Walch L, Gascard J-P, Mazmanian G, Dahlén S-E, Brink C: Antagonist resistant contractions of the porcine pulmonary artery by cysteinyl-leukotrienes. Eur J Pharmacol 401: 381-388, 2000.

7. Dahlén B, Szczeklik A, Murray JJ: Celecoxib in Patients with Asthma and Aspirin Intolerance. N Eng J Med 344: 142, 2001.

8. Prieto J, Van Der Ploeg I, Roquet A, Gigliotti D, Dahlén B, Eklund A, Grunewald J. Cytokine mRNA expression in patients with mild allergic asthma following low dose or cumulative dose allergen provocation. Clin Exp Allergy 31: 1-11, 2001.

9. Dahlén B, O'Byrne PM, Watson RM, Roquet A, Larsen F, Inman M. The reproducibility and sample size requirements of exercise-induced bronchoconstriction measurements. Eur Respir J 17:581-588, 2001.

10. Sydbom A, Blomberg A, Parnia S, Stenfors N, Sandström T, Dahlén S-E: Health effects of diesel exhaust emissions. Eur Resp J 17:733-746, 2001.

11. Echazarreta AL, Dahlén B, García G, Agustí C, Barberà JA, Roca J, Dahlén S-E, Rodriguez-Roisin R: Pulmonary gas exchange and sputum cellular responses to inhaled leukotriene D4 in asthma. Am J Respir Crit Care Med 2001; 164: 202-206.

12. Bäck M, Kumlin M, Cotgreave I, Dahlén S-E: An alternative pathway for metabolism of leukotriene D4: effects on contrations to cysteinyl-leukotrienes in the guinea pig trachea. Br J Pharmacol 133:1134-1144, 2001.

13. van Odijk J. Ahlstedt S. Bengtsson U. Hulthen L. Borres MP. Specific IgE antibodies to peanut in western Sweden--has the occurrence of peanut allergy increased without an increase in consumption?. Allergy 56(6):573-7, 2001

14. Saalman R. Dahlgren UI. Fallstrom SP. Hanson LA. Ahlstedt S. Wold AE: IgG subclass profile of serum antigliadin antibodies and antibody-dependent cell-mediated cytotoxicity in young children with coeliac disease. Scandinavian Journal of Immunology 53(1):92-8, 2001 15. Dahlén S-E, Malmström K, Nizankowska E, Dahlén B, Kuna P, Kowalski M, Lumry WR, Picado C, Stevenson DD, Bousquet J, Pauwels R, Holgate ST, Shahane A, Zhang J, TR Reiss, Szczeklik A: Improvement of aspirin-intolerant asthma by montelukast, a leukotriene receptor antagonist. A randomised, double-blind, placebo controlled trial. Am J Respir Crit Care Med 165:9-14, 2002. 16. Dahlén B, Roquet A, Inman MD, Karlsson Ö, Naya I, Anstrén G, O'Byrne PM, Dahlén S-E: Influence of zafirlukast and loratadine on exercise-induced bronchoconstriction. J. Allergy Clin Immunol 109:789-793, 2002. 17. Walch L, Norel X, Bäck M, Gascard JP, Dahlén S-E, Brink C: Pharmacologic evidence for a novel cysteinyl-leukotriene receptor subtype in human pulmonary artery smooth muscle. Br J Pharmacol 137:1339-1345, 2002. 18. Bäck M, Walch L, Norel X, Gascard JP, Mazmanian G, Brink C:Modulation of vascular tone and reactivity by nitric oxide in porcine pulmonary arteries and veins. Acta Physiol Scand.174:9-15, 2002.

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19. Sakata K, Bäck M: Receptor preferences of cysteinyl-leukotrienes in the guinea pig lung parenchyma. Eur J Pharmacol 436:119-26, 2002. 20. Löwhagen O, Wever AM, Lusuardi M, Moscato G, De Backer WA, Gandola L, Donner CF, Ahlstedt S, Larsson L, Holgate ST: The inflammatory marker serum eosinophil cationic protein (ECP) compared with PEF as a tool to decide inhaled corticosteroid dose in asthmatic patients. Respir Med 96:95-101, 2002. 21. Lin XP, Magnusson J, Ahlstedt S, Dahlman-Hoglund A, Hanson L LA, Magnusson O, Bengtsson U, Telemo E: Local allergic reaction in food-hypersensitive adults despite a lack of systemic food-specific IgE. J Allergy Clin Immunol 109:879-87, 2002. 22. Bäck M, Norel X, Walch L, Gascard JP, Dahlen SE, Brink C: The contraction of the human pulmonary artery by LTC4 is resistant to CysLT1 antagonists and counteracted by prostacyclin release. Adv Exp Med Biol 507:315-9, 2002. 23. E.S. Silverman, L. Le, A. Hallock, J. Hjoberg, T. Shikanai, K. Storm van’s Gravesande, P.E. Auron, W. Lu: Cloning and Functional Analysis of the Mouse 5-Lipoxygenase Promoter. Am J Respir Cell Mol Biol 26:475-483, 2002. 24. Berglund, B., Harju, E.-L., Kosek, E., & Lindblom, U. (2002). Quantitative and qualitative percepual analysis of cold dysesthesia and hyperalgesia in fibromyalgia. Pain, 96, 177-187. 25. Berglund, B., Hassmén, P., & Preis, A. (2002). Annoyance and spectral contrast are cues for similarity and preference of environmental sounds. Journal of Sound and Vibration, 250, 53-64. 26. Berglund, B., Hojan, E., Furmann, A., & Sworek, K. (2002). Attributes of desirable acoustic environments in some rooms. Archives of Acoustics (Poland), 27, 249-255. 27. Borg, E., & Borg, G. (2002). A comparison of AME and CR100 for scaling perceived exertion. Acta Psychologica, 109, 157-175. 28. Harju, E.-L. (2002). Cold and warmth perception mapped for age, gender and body area. Somatosensory & Motor Research, 19, 61-75. 29. Müller-Suur C, Larsson P, Larsson K, Grunevald J. Lymphocyte activation after exposure to swine dust: role of humoral mediators and phagocytic cells. Eur Respir J 2002;19:104-107. 30. Müller-Suur C, Larsson K, Grunevald J. Organic dust induced IL-12 production activates T- and NK-cells. Eur Respir J 2002;20:686-690. 31. Burvall K, Palmberg K, Larsson K. Metabolic activation of A549 human airway epithelial cells by organic dust. A study based on microphysiometry. Life Sci 2002;71:299-309. 32. Burvall K, Palmberg L, Larsson K. The tyrosine kinase inhibitor genistein increases basal cAMP and potentiates forskolin-induced cAMP accumulation in A549 human airway epithelial cells. Mol Cell Biochem 2002;240:131-133. 33. Larsson B-M, Larsson K, Malmberg P, Palmberg L. Airways inflammation after exposure in a swine confinement building during cleaning process. Am J Ind Med 2002;41:250-258. 34. Lindström M, Jönsson E, Larsson K, Lundbäck B. Underdiagnosis of chronic obstructive lung disease in northern Sweden. Int J Tubercul Dis 2001;6:76-84. 35. Laan M, Palmberg L, Larsson K, Lindén A. Free, soluble interleukin-17 protein during severe inflammation in human airways. Eur Respir J 2002;19:534-538. 36. Karlsson A-S, Hedren M, Almqvist C, Larsson K, Renström A. Evaluation of petri dish sampling for assessment of cat allergen in airborne dust. Allergy 2002;57:164-168. 37. Karlsson A-S, Renström A, Hedrén M, Larsson K. Comparison of four allergen-sampling methods in conventional and allergy prevention classrooms. Clin Exp Allergy 2002;32:1776-1781. 38. Sundblad B-M, Larsson B-M, Palmberg L, Larsson K. Exhaled nitric oxide and bronchial responsiveness in subjects exposed to organic dust. Eur Respir J 2002;20:426-431.

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39. Sundblad B-M, Larsson K. Effect of deep inhalations after a bronchial methacholine provocation in asthmatic and non-asthmatic subjects. Respir Med 2002;96:477-481. 40. Sundblad B-M, Palmberg L, Larsson K. Bronchial responsiveness to eucapnic hyperventilation and methacholine following exposure to organic dust. Chest 2002;122. 41. Nathell L, Jensen I, Larsson K. High prevalence of obesity in asthmatic patients on sick leave. Respir Med 2002;96:642-650. 42. Palmberg L, Larsson B-M, Malmberg P, Larsson K. Airway responses of healthy farmers and non-farmer to exposure in a swine confinement building. Scand J Work Environm Health 2002;28:256-263. 43. Nathell L, Larsson K, Jensen I. Determinants of undiagnosed asthma. Allergy 2002;57:687-693. 44. Perzanowski M, Rönmark E, Platts-Mills TAE, Lundbäck B. Effect of cat and dog ownership on sensitisation and development of asthma among preteenage children. Am Rev Respir Crit Care Med 2002; 166(5): 696-702. 45. Andersson F, Borg S, Jansson S-A, Jonsson A-C, Lindberg A, Prütz C, Rönmark E, Lundbäck B. The costs of exacerbations in chronic obstructive pulmonary disease. Respir Med 2002: 96: 700-708 46. Kotaniemi J, Kataja M, Hassi J, Laitinen LA, Lundbäck B. Does non-responder bias have a significant effect on results in a postal questionnaire study? Eur J Epidemiol 2002; 17: 809-817. 47. Thulin H, Björkdahl M, Karlsson A-S, Renström A. Reduction of exposure to laboratory animal allergens in a research laboratory. Annals of Occupational Hygiene 2002:46:61-68. 48. Kölbeck K-G, Sardh E, Gyllenhammar H, Palmberg L, Larsson K, Palmblad J. Modulation of plasma levels of soluble adhesion molecules and nitric oxide in healthy volunteers by exposure to swine dust. Inflammation 2002;26:291-296. 49. Pallasaho P, Meren M, Loit H-M, Sovijärvi A, Laurinen LA, Kiviloog J, Larsson K, Lundbäck B.Differences in prevalence of asthma and chronic bronchitis between Helsinki, Stockholm and Tallinn. Respir Med, 2002; 96; 759-769. 50. Wadbo M, Löfdahl C-G, Larsson K, Skoogh B-E, Tornling G, Arweström E, et al. Effects of formoterol and ipratropium bromide in COPD: a 3 months placebo-controlled study. Eur Respir J 2002;20:1138-1146. 51. Rönmark E, Perzanowski M, Platts-Mills TAE, Lundbäck B. Incidence rates and risk factors for asthma among school children: A two year follow up. Report from the Obstructive Lung Disease in Northern Sweden Studies. Respir Med 2002;96:1006-1013. 52. Renström A, Karlsson A-S, Tovey E. Nasal air sampling used for the assessment of occupational allergen exposure and the efficacy of respiratory protection. Clin Exp Allergy 2002;32:1769-1775. 53. Kotaniemi J, Pallasaho P, Sovijärvi A, Laitinen LA, Lundbäck B. Respiratory symptoms and asthma in relation to cold climate, inhaled allergens and irritants - a comparison between northern and southern Finland. J Asthma 2002; 39: 649-658. 54. Jansson S-A, Andersson F, Borg S, Ericsson Å, Jönsson E, Lundbäck B. The costs of COPD in Sweden according to disease severity. Chest 2002; 122: 1994-2002.costs of COPD in Sweden according to disease severity. Chest 2002; 122: 1994-2002. 55. Haines, M.M., Stansfeld. S.A., Job, R.F.S., Berglund, B., & Head, J. Chronic aircraft noise exposure, stress responses, mental health and cognitive performance in school children. Psychological Medicine, 2001, 31, 265-277. 56. Haines, M.M., Stansfeld, S.A., Job, R.F.S., Berglund, B., & Head, J. A follow up study of the effects of chronic aircraft noise exposure on child stress responses and cognition. International Journal of Epidemiology, 2001, 30, 839-845.

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57. Fathi M, Johansson A, Lundborg M, Orre L, Sköld CM, Camner P. Functional and morphological differences between human alveolar and interstitial macrophages. Exp Mol Pathol 70:77-82, 2001. 58. Gerde P, Muggenburg B.A, Lundborg M, Dahl A.R; The Rapid Alveolar Absorption of Diesel-Soot Absorbed Benzo(a)pyrene – Bioavailability, Metabolism, and Dosimetry of an Inhaled Carcinogen. Carcinogenesis 22, 741-749, 2001. 59. Gerde P, Scott B.R. A model for absorption of low-volatile toxicants by the airway mucosa. Inhalation Toxikology 13:903-929, 2001. 60. Klefbeck B, Svartengren K, Camner P, Philipson K, Svartengren M, Sejersen T, Mattsson E. Lung clearance in children with Duchenne Muscular Dystrophy or Spinal Muscular Atrophy with and without CPAP (Continuous Positive Airway Pressure). Exp Lung Res 27:469-484, 2001. 61. Lundborg M, Johard U, Låstbom L, Gerde P, Camner P. Human alveolar macrophage function is impaired by aggregates of ultrafine carbon particles. Environ Res Section A 86:244-253, 2001. 62. Svartengren M, Sommerer K, Scheuch G, Kohlhaeufl M, Heyder J, Falk R, Bergmann R, Hofmann W, Bailey M, Philipson K, Camner P. Comparison of clearance of particles inhaled with bolus and extremely slow inhalation techniques. Exp Lung Res 27:367-386, 2001. 63. Svens K, Ryrfeldt Å. A study of mechanisms underlying amitriptyline-induced acute lung injury. Toxicol. Appl. Pharmacol. 177:179-187, 2001. 64. Berglund, B. & Gidlöf Gunnarsson, A. Relationships between occupant personality and the sick building syndrome explored. Indoor Air, 2000, 10, 152-169. 65. Farjampour, P. & Hellström, Å. Discrimination of tone durations across the menstrual cycle. Perceptual and Motor Skills, 2000, 90, 1059-1070. 66. Svartengren, M., Strand, V., Bylin, G., Järup, L., & Pershagen, G. Short-term exposure to air pollution in a road tunnel enhances the asthmatic response to allergen. European Respiratory Journal, 2000, 15, 716-24. 67. Gross NT, Hultenby K, Mengarelli S, Camner P, Jarstrand C. Lipid peroxidation by alveolar macrophages challenged with Cryptococcus neoformans, Candida albicans and Aspergillus fumigatus. J Med Mycol 38:443-449, 2000. 68. Låstbom L, Boman A, Camner P, Ryrfeldt Å. Increased airway responsiveness after skin sensitation to 3-carene studied in isolated guinea pig lungs. Toxicology 147:209-214, 2000. 69. Philipson K, Falk R, Svartengren M, Jarvis N, Bailey M, Bergmann R, Hofmann W, Camner P. Does lung retention of inhaled particles depend on their geometric diameter? Exp Lung Res 26:437-455, 2000. 70. Zetterberg G, Elmberger G, Johansson A, Lundahl J, Lundborg M, Sköld CM, Tornling G, Camner P, Eklund A. Rat alveolar and interstitial macrophages in the fibrosing stage following quartz exposure. Hum Exp Toxicol 19:402-411, 2000. 71. Gross NT, Hultenby K, Mengarelli S, Camner P, Jarstrand C. Lipid peroxidation by alveolar macrophages challenged with Cryptococcus neoformans, Candida albicans and Aspergillus fumigatus. J Med Mycol 38:443-449, 2000. 72. Låstbom L, Boman A, Camner P, Ryrfeldt Å. Increased airway responsiveness after skin sensitation to 3-carene studied in isolated guinea pig lungs. Toxicology 147:209-214, 2000. 73. Philipson K, Falk R, Svartengren M, Jarvis N, Bailey M, Bergmann R, Hofmann W, Camner P. Does lung retention of inhaled particles depend on their geometric diameter? Exp Lung Res 26:437-455, 2000. 74. Svartengren M, Strand V, Bylin G, Järup L, Pershagen G. Short-term exposure to air pollution in a road tunnel enhances the asthmatic response to allergen. Eur Respir J 15: 716-724, 2000.

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75. Zetterberg G, Elmberger G, Johansson A, Lundahl J, Lundborg M, Sköld CM, Tornling G, Camner P, Eklund A. Rat alveolar and interstitial macrophages in the fibrosing stage following quartz exposure. Hum Exp Toxicol 19:402-411, 2000. 76. Fathi M, Johansson A, Lundborg M, Orre L, Sköld CM, Camner P. Functional and morphological differences between human alveolar and interstitial macrophages. Exp Mol Pathol 70:77-82, 2001. 77. Gerde P., Muggenburg B.A., Lundborg M., Dahl A.R.; The Rapid Alveolar Absorption of Diesel-Soot Absorbed Benzo(a)pyrene – Bioavailability, Metabolism, and Dosimetry of an Inhaled Carcinogen. Carcinogenesis 22, 741-749, 2001. 78. Klefbeck B, Svartengren K, Camner P, Philipson K, Svartengren M, Sejersen T, Mattsson E. Lung clearance in children with Duchenne Muscular Dystrophy or Spinal Muscular Atrophy with and without CPAP (Continuous Positive Airway Pressure). Exp Lung Res 27:469-484, 2001. 79. Lundborg M, Johard U, Låstbom L, Gerde P, Camner P. Human alveolar macrophage function is impaired by aggregates of ultrafine carbon particles. Environ Res 86:244-253, 2001. 80. Svartengren M, Sommerer K, Scheuch G, Kohlhaeufl M, Heyder J, Falk R, Bergmann R, Hofmann W, Bailey M, Philipson K, Camner P. Comparison of clearance of particles inhaled with bolus and extremely slow inhalation techniques. Exp Lung Res 27:367-386, 2001. 81. Camner P, Lundborg M, Lastbom L, Gerde P, Gross N, Jarstrand C: Experimental and calculated parameters on particle phagocytosis by alveolar macrophages. J Appl Physiol 92:2608-16, 2002. 82. Lundborg M, Johard U, Låstbom L, Gerde P, Jarstrand C, Camner P. Aggregates of ultrafine carbon particles impair human alveolar macrophage phagocytic function. The AnnOccupational Hygiene 46:239-241, 2002. 83. Sturm R, Hofmann W, Scheuch G, Sommerer K, Camner P, Svartengren M. Particle clearance in human bronchial airways: comparison of stochastic model predictions with experimental data. Ann Occupational Hygiene 46:329-333, 2002. 84. Barck C, Sandström T, Lundahl J Halldén G, Svartengren M Strand V Rak S, Bylin G: Ambient level of NO2 augments the inflammatory response to inhaled allergen i asthmatics. Respiratory Medicine 96: 907-917, 2002. 85. Ringdal N, Lundbäck B, Alton M, Rak S, Eivindson A, Bratten G, Kjaersgaard P. Comparable effects of inhaled fluticasone propionate and budesonide on the HPA- axis in adult asthmatic patients. Respir Med 2000; 94: 482-489. 86. Ek A, Palmberg L, Larsson K. Influence of fluticasone and salmeterol on airway effects of inhaled organic dust: an in vivo and ex vivo study. Clin Exp Immunol 2000;121:11-16. 87. Eklund L, Sundblad B-M, Malmberg P, Larsson K. The salt output of a nebulizer - a comparison between two nebulizer types. Respir Med 2000;94:139-144. 88. Kölbeck K-G, Ehnhage A, Juto J-E, Forsberg S, Gyllenhammar H, Palmberg L, et al. Airway reactivity and exhaled NO following swine dust exposure in healthy voluteers. Respir Med 2000;94:1065-1072. 89. Müller-Suur C, Larsson PH, Larsson K. T-cell activation by organic dust in vitro. Respir Med 2000;94:821-927. 90. Jenkins C, Woolcock AJ, Saarelainen P, Lundbäck B, James MH. Salmetero/fluticasone propionate combination therapy 50/250 microg twice daily is more effective than budesonide 800 microg twice daily in treating moderate to severe asthma. Respir Med 2000; 94: 715-723. 91. Lundbäck B. An introduction to studies of respiratory epidemiology in Sweden, and longitudinal data of decline in FEV1 and mortality; proportions and risk factors. Eur Respir Rev 2000; 10 (75): 453-456. 92. Nathell L, Malmberg B, Lundbäck B, Nygren Å. Is asthma underestimated as a cause of sick leave? Respir Med 2000; 94: 977-982. 93. Bousquet J, D`Urzo A, Hébert J, Barraza CH, Boulet L-P, Suárez-Chacón R, Harnest U, Lundbäck B, Martinez Morales G, Nieminen MM, Nolop KB, Visser S, Lutsky BN. Comparison of the efficacy and safety of mometasone furoate dry powder inhaler to budesonide Turbuhaler®. Eur Respir J 2000; 16: 808-816. 94. Nathell L, Malmberg B, Lundbäck B, Nygren Å. Impact of occupation on respiratory disease. Scand J Work Envir Health 2000; 26(5): 382-389. 95. Sundblad B-M, Malmberg P, Larsson K. Different response to doubling and fourfold dose increases in methacholine provocation tests in healthy subjects. Chest 2000;118:1371-1377. 96. Almqvist C, Wickman M, Perfetti L, Berglind N, Renström A, Hedrén M, et al. Worsening of asthma in children allergic to cats, after direct exposure to cat at shcool. Am J Respir Crit Care Med 2001;163:694-698. 97. Ehrs P-O, Åberg H, Larsson K. Quality of life in primary care asthma. Respir Med 2001;95:22-30. 98. Lundbäck B, Rönmark E, Jönsson E, Larsson K, Sandström T. Incidence of physician-diagnosed asthma in adults. A real incidence or a result of increased awareness. Report from the Obstructive Lung Disease in Northern Sweden Studies. Respir Med 2001;95:685-692.

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99. Mund E, Christensson B, Larsson K, Grönneberg R. Sex dependent differences in physiological ageing in the immune system of lower airways in healthy non-smoking volunteers: study of lymphocyte subsets in bronchoalveolar lavage fluid and blood. Thorax 2001;56:450-455. 100. Vesterberg O, Palmberg L, Larsson K. Albumin, transferrin and β2-macroglobulin in bronchoalveolar lavage fluid following exposure to organic dust in healthy subjects. Int Arch Occup Environ Hlth 2001;74:249-254. 101. Kotaniemi J, Lundbäck B, Nieminen M, Sovijärvi A, Laitinen L. Increase of asthma in adults in Northern Finland - a report from The FinEsS study. Allergy 2001; 56: 169-174. 102. Hasselgren M, Arne M, Lindahl A, Jansson S, Lundbäck B. Estimated prevalences of respiratory symptoms, asthma and chronic obstructive pulmonary disease related to detection rate in primary health care. Scand J Prim Health Care 2001; 19(1): 54-57. 103. Zetterlund A, Hjemdahl P, Larsson K. ß2-Adrenoceptor desensitization in human alveolar macrophages induced by inhaled terbutaline in vivo is not counteracted by budesonide. Clin Sci 2001;100:451-457. 104. Renström A, Höglund U, Björing G. Evaluation of individually ventilated cage systems for laboratory rodents. Occupational health aspects. Lab Animals, 2001; 35:42-50. 105. Höglund U, Renström A. Evaluation of individually ventilated cage systems for laboratory rodents. Cage environment and animal health aspects. Lab Animals, 2001; 35:51-57. 106. Liu X, Nickel R, Beyer K, Wahn U, Ehrlich E, Freidhoff L, Björkstén B, Beaty T, Huan SK: An IL-13 coding region variant is associated with high total serum IgE level and atopic dermatitis in German Multicenter Study (MAS-90)” Journal of Allergy and Clinical Immunology 2000:106:167-170. 107. Jenmalm MC, Björkstén B. Cord blood levels of IgG subclass antibodies to food and inhalant allergens in relation to maternal atopy and the development of atopic disease during the first eight years of life. Clinical and Experimental Allergy 2000:30:34-40. 108. Duchén K, Casas R, Fagerås-Böttcher M, Yu G, Björkstén B. Human milk polyunsaturated fatty acids and secretory immunoglobulin A antibodies and early childhood allergy. Pediatric Allergy and Immunology 2000:11:29-39. 109. Böttcher FM, Jenmalm MC, Björkstén B, Garofalo RP. Chemoattractant factors in breast milk of atopic and nonatopic mothers. Pediatric Research, 2000:47:592-597 110. Prescott SL, Jenmalm MC, Björkstén B, Holt PG. Effects of maternal allergen-specific IgG in cord blood on early postnatal development of allergen specific T-cell immunity. Allergy 2000:55:470-475. 111. Casas R, Böttcher M, Duchén K, Björkstén B. Detection of IgA antibodies to cat, �-lactoglobulin and ovalbumin allergen in human milk. Journal of Allergy and Clinical Immunology 2000:105:1236-40. 112. Sepp E, Naaber P, Voor T, Mikelsaar M, Björkstén B. Development of intestinal micro-flora during the first month of life in Estonian and Swedish infants. Microbiology, Ecology in Health and Disease, 2000:12:22-26. 113. Mutius von E, Pearce N, Beasley R, Cheng S, Ehrenstein von O, Björkstén B, Weiland S, on behalf of the ISAAC Steering Committee. International patterns of tuberculosis and the prevalence of symptoms of asthma, rhinitis and eczema. Thorax 2000:55:449-453. 114. Riikjärv MA, Annus T, Bråbäck L, Rahu K, Björkstén B. Similar prevalence of respiratory symptoms and atopy in Estonian schoolchildren with chaning life style over 4 years. European Respiratory Journal 2000:16:86-90. 115. Jenmalm MC, Aniansson-Zdolsek H, Holt PG, Björkstén B. Expression of and responses to CD2 and CD3 in 18-month-old children with and without atopic dermatitis. Pediatric Allergy and Immunology 2000:11:175-182. 116. Paronen J, Björkstén B, Hattevig G, Åkerblom H, Vaarala O. Effect of maternal diet during lactation on the development of bovine insulin-binding antibodies in children at high risk for allergy. Journal of Allergy and Clinical Immunology 2000:106:302-306. 117. Vasar M, Julge K, Björkstén B. Development of atopic sensitisation and allergic disease in early childhood. Acta Paediatrica 2000;89:523-527. 118. Pearce N, Sunyer J, Cheng S, Chinn S, Björkstén B, Burr M, Keil U, Anderson R, Burney P on behalf of the ISAAC Steering Committee and the European Respiratory Health Survey. Asthma prevalence in the European Community Respiratory Health Survey (ECRHS) and the International Study of Asthma and Allergy in Children (ISAAC). European Respiratory Journal 2000:16:420-426.. 119. Böttcher MF, Jenmalm MC, Garofalo RP, Björkstén B. Cytokines in breast milk from allergic and nonallergic mothers. Pediatric Research 2000;47:157-62. 120. Böttcher MF, Sandin A, Norin E, Midtvedt T, Björkstén B. Microflora associated characteristics in faeces from allergic and non-allergic children. Clinical and Experimental Allergy 2000:30:1590-1596. 121. Beyer K, Nickel R, Freidhoff L, Björkstén B, Huang S-K, Barnes K, McDonald S, Forster J, Zepp F, Wahn V, Beaty T, Marsh D and Wahn U: Association and linkage dysequilibrium of atopic dermatitis with chromosome 5q31-33 and 13q12-14 markers. Journal of Investigational Dermatology 2000:115:906-908. 122. Ellwood P, Asher MI, Björkstén B, Burr M, Pearce N, Robertson on behalf of the ISAAC Steering Committee. Diet and asthma, allergic rhinoconjunctivitis and atopic eczema symptom prevalence: An ecological analysis of the International Study of Asthma and Allergies in Childhood (ISAAC). European Respiratory Journal, 2001;17:436-443.

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123. Bråbäck Ö. Kjellman N-IM, Sandin A, Björkstén B. Atopy among school children in Northern and Southern Sweden in relation to pet ownership and early life events. Pediatric Allergy and Immunology 2001;12:4-10. 124. Casas R, Björkstén. Detection of Fel d1-IgG immune complexes in cord blood and sera from allergic and non-allergic mothers. Pediatric Allergy and Immunology 2001;12:.59-64 125. Anderson HR, Poloniecki, JD, Strachan DP, Beasley R, Björkstén B, Asher I on behalf of the ISAAC Steering Committee. An ecological analysis of immunisation and symptoms of atopic disease in children: Results from the International Study of Asthma and Allergies in Children (ISAAC). American Journal of Public Health, 2001;91:1126-1129. 126. Alm JS, Swartz J, Bjorksten B, Engstrand L, Engstrom J, Kuhn I, Lilja G, Mollby R, Norin E, Pershagen G, Reinders C, Wreiber K, Scheynius A: An anthroposophic lifestyle and intestinal microflora in infancy. Pediatr Allergy Immunol:402-11, 2002. 127. Montgomery SM, Ehlin AG, Sparen P, Bjorksten B, Ekbom A: Childhood indicators of susceptibility to subsequent cervical cancer. Br J Cancer 87:989-93, 2002. 128. Mai XM, Nilsson L, Kjellman NI, Bjorksten B: Hypertonic saline challenge tests in the diagnosis of bronchial hyperresponsiveness and asthma in children. Pediatr Allergy Immunol 13:361-7, 2002. 129. Rytkonen J, Karttunen TJ, Karttunen R, Valkonen KH, Jenmalm MC, Alatossava T, Bjorksten B, Kokkonen J: Effect of heat denaturation on beta-lactoglobulin-induced gastrointestinal sensitization in rats: denatured betaLG induces a more intensive local immunologic response than native betaLG. Pediatr Allergy Immunol 13:269-77, 2002. 130. Julge K, Meriste S, Kemp A, Bjorksten B: Atopic allergy and delayed type hypersensitivity in Estonian children. Clin Exp Allergy 32:1420-3, 2002. 131. Bottcher MF, Haggstrom P, Bjorksten B, Jenmalm MC: Total and allergen-specific immunoglobulin A levels in saliva in relation to the development of allergy in infants up to 2 years of age. Clin Exp Allergy 32:1293-8´, 2002. 132. Jogi R, Bjorksten B, Boman G, Janson C: Serum eosinophil cationic protein (S-ECP) in a population with low prevalence of atopy. Respir Med 96:525-9, 2002. 133. Gustafsson PA, Kjellman NI, Bjorksten B: Family interaction and a supportive social network as salutogenic factors in childhood atopic illness. Pediatr Allergy Immunol 13:51-7, 2002. 134. Benn CS, Thorsen P, Jensen JS, Kjaer BB, Bisgaard H, Andersen M, Rostgaard K, Bjorksten B, Melbye M: Maternal vaginal microflora during pregnancy and the risk of asthma hospitalization and use of antiasthma medication in early childhood. J Allergy Clin Immunol 110:72-77, 2002. Reviews

1. Dahlén S-E, Haeggström JZ, Samuelsson B, Rabe KR, Leff AL (eds): Leukotrienes as targets for the treatment of asthma and other diseases:current basic and clinical research. Am J Respir Crit Care Med 161 (2:2): S1-S153, 2000.

2. Dahlén S-E: Antileukotrienes. In: Asthma and Rhinitis (Eds Holgate ST, Busse WW), pp. 1620-1642, Blackwell, Oxford, 2000.

3. Dahlén S-E: Pharmacological Characterization of Leukotriene Receptors. Am J Respir Crit Care Med 161 (2:2): S41-S45, 2000.

4. Areskoug H, Camner P, Dahlén S-E, Låstbom L, Nyberg F, Pershagen G, Sydbom A: Particles in ambient air-a health risk assessment. Scand J Work Environ Health 26(S1):1-96, 2000.

5. Kumlin, M. Measurements of leukotrienes in humans. Am. J. Resp. Crit. Care Med. 161: S102-S106 (2000). 6. Dahlén B, Zetterstöm O, Dahlén S-E: Specific problems: Asthma induced by aspirin and other non-steroidal anti-inflammatory drugs. In: Manual of Asthma Management, 2nd Edition (Eds. O’Byrne PM and Thomson NC), pp. 453-463, Saunders, London 2001. 7. Dahlén S-E: 5-lipoxygenase inhibitors. Progr Respiratory Research 31:115-120, 2001. 8. Dahlén S-E, Brink C, Drazen JM, Evans JF, Hay DWP, Nicosia S, Serhan CN, Shimizu T: Leukotriene Receptors. In: The IUPHAR Compendium of Receptor Characterisation and Classification(2nd Ed), IUPHAR Media, 2001.

9. Bäck M: Functional characteristics of cysteinyl-leukotriene receptor subtypes. Life Sci. 71:611-22, 2002. 10. Boström C-E, Gerde P, Hanberg A, Jernström B, Johansson C, Kyrklund T, Rannug A, Törnqvist M, Victorin K, Westerholm R: Cancer risk assessment, indicators and guidelines for polycyclic aromatic hydrocarbons (PAH) in the ambient air. Environmental Health Perspectives 110(suppl. 3): 451-489, 2002.

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Skrifter i icke refereegranskade tidskrifter. Abel, E., Andersson, J. V., Dawidowicz, N., Christophersen, E., Hanssen, S. O., Lindén, A.-L., Lindvall, T., & Pasanen, A. L. (2002). The Swedish key action "The Healthy Building" - research results achieved during the first three-years period 1998-2000. In H. Levin (Ed.), Indoor Air 2002 (Vol. 2, pp. 996-1001). Santa Cruz, CA, USA: Indoor Air 2002. Axelsson, Ö. (2002). Less is more: Aesthetic appreciation of photographs explored. In: T. Kato (Ed.), IAEA 2002: Art and Environment. Osaka, Japan: The 17th Congress of Inernational Association of Empirical Aesthetics, pp. 205-208. Berglund, B. (2002). Towards a system for labeling soundscapes supportive to health. In: Abstract Guide of the IAAP Congress 2002. Singapore: International Association of Applied Psychology, p. 46. Berglund, B. (2002). Master scaling and its applications. In J.A. Da Silva, Matsushima & N. P. Ribeiro-Filho (Eds.), Fechner Day 2002, Rio de Janeiro, Brazil: International Society for Psychophysics, pp. 40-45. Berglund, B., Eriksen, C.A., & Nilsson, ME. (2002). Perceptual characterization of soundscapes in residential areas. In A. Alippi (Ed.), The 17th International Congress of Acoustics. Roma, Italy: ICA Srl, Vol VI, pp. 284-285. Berglund, B., Gidlöf Gunnarsson, A., & Job, R.F.S. (2002). Reliability and validity of a sick building syndrome questionnaire. Archives of the Center for Sensory Research, 7(2), 83-125. Berglund, B., Gidlöf Gunnarsson, A., & Job, R.F.S. (2002). Comparison of face-to-face interviews and self-completion questionnaires for assessing the sick building syndrome. Archives of the Center for Sensory Research, 7(2), 127-156. Berglund, B., Gidlöf Gunnarsson, A., & Nilsson, M.E. (2002). Model-based weighted descriptor profiles utilized for assessing the sick building syndrome. Archives of the Center for Sensory Research, 7(2), 157-206. Berglund, B., Harju, E.-L., Kosek, E., & Lindblom, U. (2002). Tactile and thermal dysfunctions in fibromyalgia and neuropathic pain patients. In: Abstract Guide of the IAAP Congress 2002. Singapore: International Association of Applied Psychology, p. 72. Berglund, B., & Nilsson, M.E. (2002). How is loudness of simultaneous and time-separated traffic noise integrated? In: Abstract Guide of the IAAP Congress 2002. Singapore: International Association of Applied Psychology, p. 66. Berglund, B., & Nilsson, M.E. (2002). Soundscapes perceived indoors and outdoors at quiet and noisy sides of apartment buildings. In A. Selamet, R. Singh & G. C. Maling (eds.) Inter-Noise 2002. Transportation Noise. Dearborn, USA: International Institute of Noise Control Engineering (I-INCE), Paper N 488. (available on CD) Berglund, B., & Zheng, L. (2002). Women’s chemical sensitivity and chemical exposures indoors and outdoors. In H. Levin (Ed.), Indoor Air 2002. Santa Cruz, CA: Indoor Air 2002, vol. 4, pp. 102-107. Borg, E. (2002). Scaling taste perception with category (C) - ratio (R) scales. In J.A. Da Silva, E.H. Matsushima & N. P. Ribeiro-Filho (Eds.), Fechner Day 2002, Rio de Janeiro, Brazil: International Society for Psychophysics, pp. 272-277. Gidlöf Gunnarsson, A. (2002). The role of residents’ perception and personality in the assessment of the sick building syndrome. Archives of the Center for Sensory Research, 7(2), 1-82. Gidlöf Gunnarsson, A. (2002). Cross-validation of an inventory for assessing SBS sensitive and SBS non-sensitive persons. Archives of the Center for Sensory Research, 7(2), 207-249. Gidlöf Gunnarsson, A. & Berglund, B. (2002). Psychological factors influencing SBS symptom reporting. In H. Levin (Ed.), Indoor Air 2002. Santa Cruz, CA: Indoor Air 2002, vol. 4, pp. 424-429. Lindvall, T. (2002). Det sunda huset. Halvtidsresultat från ett programområde 1998-2000. Miljöforskning, 3(02), 8-10.

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Nilsson, M.E., & Berglund, B. (2002). Perception of noise abatement efficiency: Evaluation of a noise barrier in an intervention study. Archives of the Center for Sensory Research, 7(1), 1-41. (In Swedish with English summary.) Renström A. Undersökning av arbetsmiljön i zooaffärer. PetScandinavia 2002;2:36-38 Berglund, B., Eriksen, C.A., & Nilsson, M.E. Exploring perceptual content in soundscapes. In E. Sommerfeld, R. Kompass, & T. Lachmann (Eds.), Fechner Day 2001. Lengerich, Germany: Pabst Science Publishers, 2001, pp. 279-284. Berglund, B., Harju, E.-L., Kosek, E., & Lindblom, U. Quantitative and qualitative perceptual analysis of cold dysesthesia and hyperalgesia in fibromyalgia. Archives of the Center for Sensory Research, 2001, 6(2), 77-93. Berglund, B., Harju, E-L., & Lindblom, U. Master scaling calibrates the pain patient’s perceived intensity scales for touch, cold and warmth. Archives of the Center for Sensory Research, 2001, 6(2), 9-29. Berglund, B., Harju, E.-L., & Lindblom, U. Central and peripheral neuropathic pain characterized by perceived intensity and quality of touch, cold and warmth. Archives of the Center for Sensory Research, 2001, 6(2), 31-53. Berglund, B. & Lindvall, T. Olfaction. In S. Kuwano (Ed.), Handbook of human factors. Asakura Publishing Co. ltd., Japan, 2001. [transl. to Japanese] Berglund, B. & Lindvall, T. The olfactory environment. In S. Kuwano (Ed.), Handbook of human factors. Asakura Publishing Co. ltd., Japan, 2001. [transl. to Japanese] Berglund, B. & Nilsson, M.E. Variation in perceived soundscape due to shielding building and facade. In R. Boone (Ed.), Inter Noise 2001. The Hague, The Netherlands, 2001, Vol. 3, pp. 1253-1256. Berglund, B. & Nilsson, M.E. An attempt to capture the perceived soundscape. In: Abstract Book from NOPHER 2001: An International Symposium on Noise Pollution & Health. London, UK: Institute of Laryngology & Otology, University College of London, 2001, p. 60. Berglund, B. & Nilsson, M.E. Total annoyance (or total loudness) models of combined community sounds. Archives of the Center for Sensory Research, 2001, 6(3), 33-59. Berglund, B. & Nilsson, M.E. Identification of sounds from traffic. Archives of the Center for Sensory Research, 2001, 6(3), 61-70. Berglund, B. & Nilsson, M.E. Total and source-specific loudness of singular and combined traffic sounds. Archives of the Center for Sensory Research, 2001, 6(3), 71-93. Berglund, B. & Nilsson, M.E. Total and source-specific loudness of simultaneous and time-separated traffic sounds. Archives of the Center for Sensory Research, 2001, 6(3), 95-103. Borg, E. A Comparison between two rating scales for perceived exertion. In E. Sommerfeld, R. Kompass & T. Lachmann (Eds.), Fechner Day 2001. Lengerich, Germany: Pabst Science Publishers, 2001, pp. 298-302. Fruhstorfer, H., Harju, E-L., & Lindblom, U. The significance of A-delta and C fibres for the perception of synthetic heat. Archives of the Center for Sensory research, 2001, 6, (2), 95-111. Harju, E-L. Cold and warmth perception mapped for age, gender and body area. Archives of the Center for Sensory Research, 2001, 6, 55-76. Kihlman, T., Kropp, W., Öhrström, E., & Berglund, B. Soundscape support to health. A cross-disciplinary research program. In R. Boone (Ed.), Inter Noise 2001. The Hague, The Netherlands, 2001, Vol. 3, pp. 1237-1242. Nilsson, M.E. Loudness integration of simultaneous and successive traffic sounds. Archives of the Center for Sensory Research, 2001, 6(3), 105-117. Nilsson, M.E. & Berglund, B. Effects of noise from combinations of traffic sources. Archives of the Center for Sensory Research, 2001, 6(1), 1-59.

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Gerde, P., B. A. Muggenburg, et al. (2001). Epithelial penetration and clearance of particle-borne benzo(a)pyrene. Cambridge, Massachusetts, Health Effects Institute: 1-25. Berglund, B., Gidlöf Gunnarsson, A., & Nilsson, M.E. Weighted descriptor profiles as an alternative method to measure the sick building syndrome. In O. Seppänen & J. Säteri (Eds.), Healthy Buildings 2000, Vol. 1: Exposure, human responses and building investigations. Helsinki: SIY Air Information Oy, 2000, pp. 597-602. Berglund, B., Granström, N., Harju, E.-L., & Lindblom, U. Warmth and cold intensity functions over twenty neurologically critical body areas tested with thermorollers. In: Abstract Book of the 23rd Annual Meeting of the Scandinavian Association for the Study of Pain (SASP). Bergen, Norway: SASP, 2000, p. 50. Berglund, B., Hassmén, P., & Preis, A. Similarity and preferences in relation to annoyance of environmental sounds. In: Abstract Book of the 4th Japanese-Swedish Noise Symposium on Medical Effects, 2000. Gothenburg, Sweden: Göteborg University, p. 56. Berglund, B., & Nilsson, M.E. The potential of master scaling of perceptual attributes in social surveys. In D. Cassereau (Ed.), Inter Noise 2000. Bron, France: INRETS, 2000, Vol. 3, pp. 1593-1596. Berglund, B., & Nilsson, M.E. Total annoyance and perceptually discernible noise sources. In D. Cassereau (Ed.), Inter Noise 2000, Bron, France: INRETS, 2000, Vol. 6, pp. 3541-3544. Harju, E-L. Thermal sensitivity differ when assessed as perceived intensity and absolute threshold. In C. Bonnet (Ed.), Fechner Day 2000. Strasbourg, France: The International Society for Psychophysics, 2000, pp. 303-308. Lindblom, B. & Berglund, B. New methods for bedside assessment of temperature sensibility in pain patients. In: Pain in Europe III, Advances in Pain Research and Therapy. Nice, France: European Association for the Study of Pain [EASP], 2000, PS2/356, p. 359. Tuveson, B., Lindblom, U., & Fruhstorfer, H. Experimental muscle pain with referral provokes delayed alterations of thermal perception thresholds. In: Pain in Europe III, Advances in pain research and therapy. Nice, France: European Association for the Study of Pain [EASP], 2000, PS1/022, p. 210.

Lockne G, Dahlén S-E(eds): Allergi och annan överkänslighet i luftvägarna, Hjärt-Lungfondens Kvartalsskrift, Årgång 95, Häfte 2, 2000. Larsson K. Astmadiagnostik. In: Bäcklund L, Hedenstierna G, Hedenström H, editors. Lungfysiologi och diagnostik vid lungsjukdom. Lund: Studentlitteratur; 2000. p. 225-238. Larsson K. Astma och sport. Sollentuna: Orion Pharma AB; 2000. Larsson K, editor. Lungsjukdomar - motion och träning. Lund: Elander Skogs Grafiska; 2000. Larsson K. Ansträngningsutlöst bronkobstruktion vid astma. In: Larsson K, editor. Lungsjukdomar - motion och träning. Lund: Elander Skogs Grafiska; 2000. p. 32-45. Larsson K. Astma hos idrottsutövare. In: Larsson K, editor. Lungsjukdomar - motion och träning. Lund: Elander Skogs Grafiska; 2000. p. 70-75. Larsson K. Isocyanatexpoering. En riskfaktor i arbetslivet. Allergi i praksis 2000;3/2000:41-43. Larsson K. KOL, en onödig folksjukdom. Forskning och Framsteg 2001;2/01:24-28. Larsson K. Adrenerga och antikolinerga läkemedel vid behandling av KOL. Lungeforum 2001;11:20-24.