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Vaccine acceptance or refusal?: Individual choice vs societal needs or My risks vs “our” risks Heidi J. Larson The Vaccine Confidence Project Faculty of Epidemiology and Population Health LSHTM

Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

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Page 1: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Vaccine acceptance or refusal

Individual choice vs societal needs

or

My risks vs ldquoourrdquo risks

Heidi J Larson

The Vaccine Confidence Project

Faculty of Epidemiology and Population Health

LSHTM

Risk as feelings

(fast instinctive emotional )

Risk as analysis

(logic reason scientific)

Risk as Politics

Adapted from Slovic et al Risk Analysis 2004 24 (2) 311-22

So what do we need to do bull Scientists (and the Media) must not to treat fear

and reservation as ignorance and then try to destroy them with a blunt ldquorationalrdquo instrument

Pattison ndash BMJ 2001323838-840

In the 19th Century

bull Principles were not well understood

bull Vaccination is ineffective

bull Vaccination is not safe

bull Religious and philosophical concerns

bull Resistance to compulsory vaccination

In the 21st Century

bull Principles STILL not well understood

bull Perception that vaccination is not needed

bull Concerns about vaccine safety

bull Religious and philosophical concerns

bull Resistance to compulsory vaccination

Reasons for vaccine hesitancy and opposition

Heidilarsonlshtmacuk

Vaccine hesitancy and risk perception

heidilarsonlshtmacuk

WHO Guidance

But what about the perception of safety

Prompters of questions and risk perceptions

bull Adverse Event (AEFI) ndashlocal AEFI are usually stronger prompters of rumors but a distant event reported can also spread and provoke questions

bull New research reported

bull New recommendation or policy change

bull New product (introduction of new product or product packaging)

LarsonRestoring Public Trust

httpwwwgmofreeglobalorgenmission

Perceptions are also about motives

World Economic Forum Global Risks 2013

Heidilarsonlshtmacuk

OPPORTUNITY or

RISK

The role of social media

2013 Global Risks Report -World Economic Forum

Heidilarsonlshtmacuk

Report of the Independent Monitoring Board of the Global Polio Eradication Initiative November 2012

Result of 2003-2004 rumour-driven

vaccine boycott

Heidilarsonlshtmacuk

Herd immunity or Herd mentality

Wakefield Lancet Article

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 2: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Risk as feelings

(fast instinctive emotional )

Risk as analysis

(logic reason scientific)

Risk as Politics

Adapted from Slovic et al Risk Analysis 2004 24 (2) 311-22

So what do we need to do bull Scientists (and the Media) must not to treat fear

and reservation as ignorance and then try to destroy them with a blunt ldquorationalrdquo instrument

Pattison ndash BMJ 2001323838-840

In the 19th Century

bull Principles were not well understood

bull Vaccination is ineffective

bull Vaccination is not safe

bull Religious and philosophical concerns

bull Resistance to compulsory vaccination

In the 21st Century

bull Principles STILL not well understood

bull Perception that vaccination is not needed

bull Concerns about vaccine safety

bull Religious and philosophical concerns

bull Resistance to compulsory vaccination

Reasons for vaccine hesitancy and opposition

Heidilarsonlshtmacuk

Vaccine hesitancy and risk perception

heidilarsonlshtmacuk

WHO Guidance

But what about the perception of safety

Prompters of questions and risk perceptions

bull Adverse Event (AEFI) ndashlocal AEFI are usually stronger prompters of rumors but a distant event reported can also spread and provoke questions

bull New research reported

bull New recommendation or policy change

bull New product (introduction of new product or product packaging)

LarsonRestoring Public Trust

httpwwwgmofreeglobalorgenmission

Perceptions are also about motives

World Economic Forum Global Risks 2013

Heidilarsonlshtmacuk

OPPORTUNITY or

RISK

The role of social media

2013 Global Risks Report -World Economic Forum

Heidilarsonlshtmacuk

Report of the Independent Monitoring Board of the Global Polio Eradication Initiative November 2012

Result of 2003-2004 rumour-driven

vaccine boycott

Heidilarsonlshtmacuk

Herd immunity or Herd mentality

Wakefield Lancet Article

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 3: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

So what do we need to do bull Scientists (and the Media) must not to treat fear

and reservation as ignorance and then try to destroy them with a blunt ldquorationalrdquo instrument

Pattison ndash BMJ 2001323838-840

In the 19th Century

bull Principles were not well understood

bull Vaccination is ineffective

bull Vaccination is not safe

bull Religious and philosophical concerns

bull Resistance to compulsory vaccination

In the 21st Century

bull Principles STILL not well understood

bull Perception that vaccination is not needed

bull Concerns about vaccine safety

bull Religious and philosophical concerns

bull Resistance to compulsory vaccination

Reasons for vaccine hesitancy and opposition

Heidilarsonlshtmacuk

Vaccine hesitancy and risk perception

heidilarsonlshtmacuk

WHO Guidance

But what about the perception of safety

Prompters of questions and risk perceptions

bull Adverse Event (AEFI) ndashlocal AEFI are usually stronger prompters of rumors but a distant event reported can also spread and provoke questions

bull New research reported

bull New recommendation or policy change

bull New product (introduction of new product or product packaging)

LarsonRestoring Public Trust

httpwwwgmofreeglobalorgenmission

Perceptions are also about motives

World Economic Forum Global Risks 2013

Heidilarsonlshtmacuk

OPPORTUNITY or

RISK

The role of social media

2013 Global Risks Report -World Economic Forum

Heidilarsonlshtmacuk

Report of the Independent Monitoring Board of the Global Polio Eradication Initiative November 2012

Result of 2003-2004 rumour-driven

vaccine boycott

Heidilarsonlshtmacuk

Herd immunity or Herd mentality

Wakefield Lancet Article

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 4: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

In the 19th Century

bull Principles were not well understood

bull Vaccination is ineffective

bull Vaccination is not safe

bull Religious and philosophical concerns

bull Resistance to compulsory vaccination

In the 21st Century

bull Principles STILL not well understood

bull Perception that vaccination is not needed

bull Concerns about vaccine safety

bull Religious and philosophical concerns

bull Resistance to compulsory vaccination

Reasons for vaccine hesitancy and opposition

Heidilarsonlshtmacuk

Vaccine hesitancy and risk perception

heidilarsonlshtmacuk

WHO Guidance

But what about the perception of safety

Prompters of questions and risk perceptions

bull Adverse Event (AEFI) ndashlocal AEFI are usually stronger prompters of rumors but a distant event reported can also spread and provoke questions

bull New research reported

bull New recommendation or policy change

bull New product (introduction of new product or product packaging)

LarsonRestoring Public Trust

httpwwwgmofreeglobalorgenmission

Perceptions are also about motives

World Economic Forum Global Risks 2013

Heidilarsonlshtmacuk

OPPORTUNITY or

RISK

The role of social media

2013 Global Risks Report -World Economic Forum

Heidilarsonlshtmacuk

Report of the Independent Monitoring Board of the Global Polio Eradication Initiative November 2012

Result of 2003-2004 rumour-driven

vaccine boycott

Heidilarsonlshtmacuk

Herd immunity or Herd mentality

Wakefield Lancet Article

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 5: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Vaccine hesitancy and risk perception

heidilarsonlshtmacuk

WHO Guidance

But what about the perception of safety

Prompters of questions and risk perceptions

bull Adverse Event (AEFI) ndashlocal AEFI are usually stronger prompters of rumors but a distant event reported can also spread and provoke questions

bull New research reported

bull New recommendation or policy change

bull New product (introduction of new product or product packaging)

LarsonRestoring Public Trust

httpwwwgmofreeglobalorgenmission

Perceptions are also about motives

World Economic Forum Global Risks 2013

Heidilarsonlshtmacuk

OPPORTUNITY or

RISK

The role of social media

2013 Global Risks Report -World Economic Forum

Heidilarsonlshtmacuk

Report of the Independent Monitoring Board of the Global Polio Eradication Initiative November 2012

Result of 2003-2004 rumour-driven

vaccine boycott

Heidilarsonlshtmacuk

Herd immunity or Herd mentality

Wakefield Lancet Article

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 6: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

WHO Guidance

But what about the perception of safety

Prompters of questions and risk perceptions

bull Adverse Event (AEFI) ndashlocal AEFI are usually stronger prompters of rumors but a distant event reported can also spread and provoke questions

bull New research reported

bull New recommendation or policy change

bull New product (introduction of new product or product packaging)

LarsonRestoring Public Trust

httpwwwgmofreeglobalorgenmission

Perceptions are also about motives

World Economic Forum Global Risks 2013

Heidilarsonlshtmacuk

OPPORTUNITY or

RISK

The role of social media

2013 Global Risks Report -World Economic Forum

Heidilarsonlshtmacuk

Report of the Independent Monitoring Board of the Global Polio Eradication Initiative November 2012

Result of 2003-2004 rumour-driven

vaccine boycott

Heidilarsonlshtmacuk

Herd immunity or Herd mentality

Wakefield Lancet Article

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 7: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Prompters of questions and risk perceptions

bull Adverse Event (AEFI) ndashlocal AEFI are usually stronger prompters of rumors but a distant event reported can also spread and provoke questions

bull New research reported

bull New recommendation or policy change

bull New product (introduction of new product or product packaging)

LarsonRestoring Public Trust

httpwwwgmofreeglobalorgenmission

Perceptions are also about motives

World Economic Forum Global Risks 2013

Heidilarsonlshtmacuk

OPPORTUNITY or

RISK

The role of social media

2013 Global Risks Report -World Economic Forum

Heidilarsonlshtmacuk

Report of the Independent Monitoring Board of the Global Polio Eradication Initiative November 2012

Result of 2003-2004 rumour-driven

vaccine boycott

Heidilarsonlshtmacuk

Herd immunity or Herd mentality

Wakefield Lancet Article

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 8: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

httpwwwgmofreeglobalorgenmission

Perceptions are also about motives

World Economic Forum Global Risks 2013

Heidilarsonlshtmacuk

OPPORTUNITY or

RISK

The role of social media

2013 Global Risks Report -World Economic Forum

Heidilarsonlshtmacuk

Report of the Independent Monitoring Board of the Global Polio Eradication Initiative November 2012

Result of 2003-2004 rumour-driven

vaccine boycott

Heidilarsonlshtmacuk

Herd immunity or Herd mentality

Wakefield Lancet Article

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 9: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

World Economic Forum Global Risks 2013

Heidilarsonlshtmacuk

OPPORTUNITY or

RISK

The role of social media

2013 Global Risks Report -World Economic Forum

Heidilarsonlshtmacuk

Report of the Independent Monitoring Board of the Global Polio Eradication Initiative November 2012

Result of 2003-2004 rumour-driven

vaccine boycott

Heidilarsonlshtmacuk

Herd immunity or Herd mentality

Wakefield Lancet Article

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 10: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

2013 Global Risks Report -World Economic Forum

Heidilarsonlshtmacuk

Report of the Independent Monitoring Board of the Global Polio Eradication Initiative November 2012

Result of 2003-2004 rumour-driven

vaccine boycott

Heidilarsonlshtmacuk

Herd immunity or Herd mentality

Wakefield Lancet Article

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 11: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Report of the Independent Monitoring Board of the Global Polio Eradication Initiative November 2012

Result of 2003-2004 rumour-driven

vaccine boycott

Heidilarsonlshtmacuk

Herd immunity or Herd mentality

Wakefield Lancet Article

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 12: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Herd immunity or Herd mentality

Wakefield Lancet Article

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 13: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Wakefield Lancet Article

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 14: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

17

Determinants of vaccine hesitancy

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review

of published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 15: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Understanding vaccine hesitancy around vaccines and vaccination from a global perspective A systematic review of

published literature 2007-2012 Larson HJ Jarrett C Eckersberger E Smith DM Paterson P Vaccine 2014 Apr 1732(19)2150-2159

Articles about vaccine hesitancy by year and WHO region [n = 1164]

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 16: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Can we monitor public confidence in

vaccines

Heidilarsonlshtmacuk

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 17: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Heidilarsonlshtmacuk

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 18: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Tracking Anti-vaccination Sentiment in Eastern European Social Media Networks

UNICEF2013

Influences on risk perceptions are highly varied

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 19: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Tracking Anti-vaccination Sentiment in Eastern European

Social Media Networks UNICEF2013

Modes of communication differ by location

Heidilarsonlshtmacuk

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 20: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Perceptions of risk can have serious impacts

bull In the Philippines risk perceptions that

tetanus vaccines caused sterilization led to a

45 drop in coverage between 1994 and 1995

bull In 1998 Andrew Wakefieldrsquos publication linking MMR vaccine to bowel disease and autism caused public confidence to plummet MMR coverage rates in England dropped from nearly 93 in 1997 to 799 in 2003-04 due to risk perceptions

bull In Japan adverse events following HPV vaccination amplified by negative media and a highly vocal victim support group led the government to withdraw their HPV recommendation (despite no evidence of vaccine-link) and HPV vaccine uptake plummeted from over 70 to under 10 between 2013-2014

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 21: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Vaccine Risk Perceptions and Ad Hoc Risk Communication

An Empirical AssessmentDan M Kahan

Although perceptions may seem to not have an immediate impact they can have longer term impacts

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 22: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

NAIROBI MAY 2013 (25 years post-MMR Wakefield scaremdashrisk perceptions travel)

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 23: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

heidilarsonlshtmacuk

The nature of vaccine concerns also vary

Globally by vaccine and over time

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 24: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

heidilarsonlshtmacuk

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 25: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Larson et al Measuring Vaccine Confidence Lancet ID 2013

POSITIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 26: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

NEGATIVE SENTIMENT REPORTS

Heidilarsonlshtmacuk

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 27: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

New research shows

that trying to change

negative perceptions

can make things worse

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 28: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Source Peter Sandman httpwwwpsandmancomarticleszurichpdf

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 29: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Culture

Personal Beliefs

Politics

Society Scientific Evidence

Media

TRUST

TRUST and RESPECT can be the tipping point

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 30: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

Larson et al Drug Safety 2012 35(11)

Riskbenefit communication is only part of an

ongoing dynamic processhellip

wwwvaccineconfidenceorg

Page 31: Vaccine acceptance or refusal? - ema.europa.eu · Understanding vaccine hesitancy around vaccines and vaccination from a global perspective: A systematic review of published literature,

wwwvaccineconfidenceorg