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Iron deficiency in childhood
Uijterschout, L.
Publication date2015Document VersionFinal published version
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Citation for published version (APA):Uijterschout, L. (2015). Iron deficiency in childhood.
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Download date:17 May 2021
Lieke Uijterschout
Iron deficiency in childhood
Lieke Uijterschout
Iron deficiency in childhood
Lieke Uijterschout
Iron deficiency in childhood
Iron deficiency in childhood
© L. Uijterschout2014 Den Haag
Vormgeving en opmaakDe VormCompagnie, Houten
DrukDR&DV Media Services, Amsterdam
De studies beschreven in dit proefschrift zijn mede mogelijk gemaakt door ontvangst van een unrestricted grant van het wetenschapsfonds van het HagaZiekenhuis, de non-profit stichting de ‘Stichting Vrienden van het JKZ’, Nutricia bv, en Chiemsi Pharmaceuticals bv.
Promotiereeks HagaZiekenhuis
Het HagaZiekenhuis van Den Haag is trots op medewerkers die fundamentele bijdragen leveren aan de wetenschap en stimuleert hen daartoe. Om die reden biedt het HagaZiekenhuis promovendi de mogelijkheid hun dissertatie te publiceren in een speciale Haga uitgave, die onderdeel is van de promotiereeks van het HagaZiekenhuis. Daarnaast kunnen promovendi in het wetenschaps magazine HagaScoop van het ziekenhuis aan het woord komen over hun promotieonderzoek.
AC A D E M I S C H P R O E F S C H R I F T
ter verkrijging van de graad van doctor
aan de Universiteit van Amsterdam
op gezag van de Rector Magnificus
prof. dr. D.C. van den Boom
ten overstaan van een door het College voor Promoties ingestelde
commissie, in het openbaar te verdedigen in de Agnietenkapel
op vrijdag 27 maart 2015, te 14:00 uur
door Lieke Uijterschout
geboren te Almelo
Lieke Uijterschout
Iron deficiency in childhood
Promotiecommissie:
Promotor: Prof. dr. J.B. van GoudoeverCopromotor: Dr. F. BrusOverige leden: Prof. dr. R.J.B.J. Gemke Prof. dr. D.W. Swinkels Prof. dr. W.M.C. van Aalderen Dr. E. Lopriore Prof. dr. R.A. Hira Sing Prof. dr. M. Boele van Hensbroek
Faculteit der Geneeskunde
Contents
Chapter 1 General introduction 8
Part I Iron deficiency in preterm infants born after 32 to 37 weeks of gestational age
34
Chapter 2 Iron deficiency in the first six months of age in infants born after 32 to 37 weeks of gestational age
36
Chapter 3 Serum hepcidin in infants born after 32 to 37 weeks of gestational age
52
Part II Iron deficiency in healthy, young children 72
Chapter 4 Prevalence and risk factors of iron deficiency in healthy young children in the Southwestern region of the Netherlands
74
Chapter 5 The value of RetHb and sTfR in the diagnosis of iron depletion in healthy, young children
92
Chapter 6 Serum hepcidin measured by immunochemical and massspectrometric methods and their correlation with iron status indicators in healthy children aged 0.5 to 3 years
108
Chapter 7 The influences of factors associated with decreased iron supply to the fetus during pregnancy on iron status in healthy children aged 0.5 to 3 years
128
Chapter 8 Dietary sources of iron in children aged 1 to 4 years visiting daycare
142
Part III Iron deficiency in children with cystic fibrosis 152
Chapter 9 Iron deficiency occurs frequently in children with Cystic Fibrosis
154
Chapter 10 The value of soluble transferrin receptor and hepcidin in the assessment of iron status in children with cystic fibrosis
168
Chapter 11 General discussion 186
Chapter 12 Summary 212
Samenvatting 221
Chapter 13 List of publications 228
Curriculum Vitae 232
Dankwoord 234
Addendum 236
