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US TOO US TOO INTERNATIONAL, INCINTERNATIONAL, INC
US TOO GREATER QUAD US TOO GREATER QUAD CITIES PROSTATE CANCER CITIES PROSTATE CANCER
SUPPORT GROUPSUPPORT GROUP
STATISTICS:PROSTATE CANCERSTATISTICS:PROSTATE CANCER• The prostate is the #1 Cancer site in men
• 220K men are diagnosed each year
• The number of new prostate cancer cases will rise sharply as the “Baby Boomers” come of age
• 29K men die of prostate cancer each year (down from 40K men that used to die each year before DRE and PSA screenings were used
• AFRICAN-AMERICAN men have prostate cancer death rates over twice those of Caucasians (53.7/100K men VS. 24.1/10K)
• 1 in 6 men will develop Prostate Cancer
• Each person w/ Prostate CA is someone’s father, uncle, brother, son, etc.
• With early detection, prostate cancer has an 85-95% cure rate
• In early stages, treatments are far less traumatic
Relationship of the PSA Level to thePrevalence of Prostate Cancer and High-Grade Disease
PSA Level # of men Men with Men with hi-grade (N=2950) Prost. CA Prost. CA
(N=449) (N+67)
0 - 0.5 ng/ml 496 32(6.6) 4/32 (12.5)0.6-1.0 ng/ml 791 80 (10.1) 8/80 (10.0)1/1-2/0 ng/ml 998 170 (17.0) 20/170 (11.8)2.1-3.0 ng/ml 482 115 (23.9) 22/115 (19.1)3.1-4.0 ng/ml 193 52 (26.9) 13/52 (25.0)
*High-grade disease = Gleason score > 7. PSA < 4.0 ng/ml. Reproduced with permission from: Thompson, M, Pauler, DK, Goodman, PJ, et al. N
Engl J Med 2004; 350:2239. Copyright C 2004 Massachusetts Medical. Prevalence of prostate cancer among men with a prostate-specific antigen level >4.0 ng
Prostate cancer is NOTProstate cancer is NOT just an old man’s disease! just an old man’s disease!
• Literature on prostate cancer usually states that older men in their 60s or 70s are more likely to get the disease.
• More men in their late 40s and early 50s are being diagnosed with prostate cancer.
SYMPTOMS: PROSTATE CANCERSYMPTOMS: PROSTATE CANCER
• NO SYMPTOMS (EARLY STAGE CA)• Blood in urine• Pain or difficulty urinating• Increased frequency of urination, often at night• Increased urgency to urinate• Inability to urinate• Pain/discomfort in area of prostate (near rectum)• Unexplained weight loss• Unusual, persistent bone pain (usually spine)
PROSTATE CANCER:PROSTATE CANCER:THE GENETIC LINKTHE GENETIC LINK
• NO FAMILY HISTORY OF CANCER (CA)
• FAMILY HISTORY OF CA OTHER THEN PROSTATE
• BOTH PARENTS W/ CA OTHER THEN PROSTATE
• DAD w/ PROSTATE CA, MOM w/ OTHER CANCER
• FATHER AND UNCLES(S) WITH PROSTATE CA
• GRAMPA, DAD & UNCLE(S) HAD PROSTATE CA
• 1 in 9 (11.2%)
• 2 in 9 (18.9%)
• 2 in 5 (42.6%)
• 1 in 2 (53.1%)
• 3 in 5 (61,7%)
• 4 in 5 (86.3%)
WHO SHOULD BE SCREENED?WHO SHOULD BE SCREENED?
Men over 40 w/ risks: Annual DRE &PSA (African American or w/ family history)
All men by age 45: Annual DRE & PSA
THE BENEFITS OF SCREENINGTHE BENEFITS OF SCREENING
Peace of mind!
Catching prostate CA early
Improving your odds of surviving
Detecting CHANGES in PSA
PSA: WHAT YOU SHOULD KNOW PSA: WHAT YOU SHOULD KNOW
• PSA stands for Prostate Specific Antigen
• All men should get a baseline PSA by age 45, then annually thereafter
• All men should know their PSA number
• Men should keep track of changes in their PSA # over time
• Don’t accept this answer from your Dr: “Your PSA is normal”
WHAT IS A “GOOD” PSA READING?WHAT IS A “GOOD” PSA READING?
• One that stays CONSTANT!
• An increase of 25% in one year means you should get checked again in 6 months
• If PSA continues to rise sharply, get biopsy
PROSTATE CANCER PROSTATE CANCER TREATMENT OPTIONSTREATMENT OPTIONS
• RADICAL PROSTATECTOMY– Perineal
– Retropubic*
– Laproscopic*
*Nerve Sparing Procedures
PROSTATE CANCER PROSTATE CANCER TREATMENT OPTIONSTREATMENT OPTIONS
RADIATION THERAPY
• External Radiation
– IMRT: Intensity-Modulated Radiation Therapy– Conformal Radiation– 3-D Radiation– Proton Beam Radiation
PROSTATE CANCER PROSTATE CANCER TREATMENT OPTIONSTREATMENT OPTIONS
• BRACKYTHERAPY (Internal Radiation)
– Paladium Seeds
– Iodine Seeds
– High Dose Therapy
PROSTATE CANCER PROSTATE CANCER TREATMENT OPTIONSTREATMENT OPTIONS
• Hormone Therapy
• Cryotherapy
• Thermal Therapy
• Watchful Waiting
WHAT YOU NEED TO KNOW WHAT YOU NEED TO KNOW ABOUT PROSTATE CANCERABOUT PROSTATE CANCER
• If you have a family history, include DRE and PSA in your annual checkups
• Get to know your PSA numbers (make sure your PSA numbers are stable)